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Synthetic and Systems Biotechnology 封面图

Synthetic and Systems Biotechnology

IF4.4
论文数363
被引数1716
期刊论文 363
发表时间
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A modular in vitro multienzyme cascade for the sustainable synthesis of high-value vidarabine 5′-monophosphate from adenosine模块化体外多酶级联反应用于可持续合成高价值阿糖腺苷-5′-单磷酸酯
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-10-16
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deleteWeiwei Su; Xiaofan Zhang; Rongrong Li; Kaige Li; Xiaojia Guo; Xiaobei Liu; Zhenyu Wang; Hailei Wang; Yuxue Liu
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Screening a thermotolerant Komagataella phaffii strain with methanol cross-tolerance and the associated physiological and transcriptional responses筛选一株对甲醇存在交叉耐受的热耐受性Komagataella phaffii菌株及其相关的生理和转录响应
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-10-15
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deleteChaoyin Li; Tianzhi Jiang; Yesong Bo; Zhenghui Lu; Yuling Zhou; Guimin Zhang
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Plug-and-Play or Plug-and-Pray? Impact of random versus targeted integration on the linearity and orthogonality of synthetic gene circuits in CHO cells插即用还是插即祈祷？随机与靶向整合对CHO细胞中合成基因线路的线性和正交性的影响
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IF4.4
delete2026-10-15
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deleteSheryl Li Yan Lim; Lars K. Nielsen; Ioscani Jiménez del Val; Jesús Lavado-García
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A base-editing and auxotrophic selection platform for linking epigenetic regulators to silent biosynthetic gene clusters in Aspergillus nidulans基于碱基编辑和营养缺陷型筛选的平台，用于连接烟曲霉中的表观遗传调控因子与沉默的生物合成基因簇
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IF4.4
delete2026-10-13
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deleteMeng Pang; Donghui Guo; Yanling Li; Yuze Chen; Rumeng Du; Jiayang Liu; Jiahui Hu; Hang Li; Zhuofan Li; Guojun Pan; Yuan Tian; Fanglong Zhao
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Systems metabolic engineering of a plasmid-free Escherichia coli cell factory for high-level cytidine production质粒游离大肠杆菌细胞工厂的高水平胞苷生产系统代谢工程
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-09-22
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deleteRunze Zhao; Changgeng Li; Chaoye Xu; Zhichao Chen; Haibo Xiong; Zichen Yu; Tang’en Shi; Lanxiao Li; Meng Yuan; Ling Ma; Siyu Zhao; Hongyu Deng; Qingyang Xu
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Harnessing synthetic microbial communities for desert vegetation restoration利用合成微生物群落进行沙漠植被恢复
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-09-19
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deletePanpan Zhang; Haibing Wang; Xiaopeng Jia; Xiaopei Zhang
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A 6His-2Flag dual-tag strategy enables high-yield production of antimicrobial peptide N6 in Pichia pastoris to combat multidrug-resistant Klebsiella pneumonia6His-2Flag双标签策略实现抗菌肽N6在Pichia pastoris中的高产制备以对抗多药耐药Klebsiella pneumonia
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-09-18
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deleteYexuan Wang; Manli Cao; Mengyin Deng; Na Yang; Da Teng; Ya Hao; Keye Xu; Jianhua Wang; Ruoyu Mao
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Hijacking host RNA polymerase for processive in situ mutagenesis劫持宿主RNA聚合酶以进行高效的原位诱变
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IF4.4
delete2026-09-18
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deleteYuou Sheng; Huizhen Ni; Shihao Yang; Wenliang Hao; Chong Zhang
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Artificial gene clusters designed for simultaneous multi-gene expression enable reconstruction of metabolite biosynthesis pathways in Trichoderma reesei为同时多基因表达设计的合成基因簇使里氏木霉中代谢物生物合成途径的重建成为可能
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IF4.4
delete2026-09-17
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deleteLei Wang; Yaqi Dang; Chentao Luan; Zitong Yan; Xianjun Wang; Zhizhi Ma; Xia Zhang; Ruifang Ao; Bin Liu; Zhizhen Liu; Peng Shi; Jun Xie
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Genetic engineering of cyanophages for harmful cyanobacterial bloom treatment—A mini review利用基因工程改造蓝藻病毒以处理有害蓝藻水华——一篇小型综述
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IF4.4
delete2026-09-15
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deleteErin E. Peters; Ping Gong
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Directed biosynthesis of the designer peptidyl nucleoside antibiotics featuring a simplified azetidine-containing moiety设计肽核苷类抗生素的定向生物合成，其特征是含有简化的氮杂环丁烷基结构单元
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IF4.4
delete2026-09-08
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deleteRong Gong; Tianzhu Li; Liwei Zhou; Yuanyuan Liu; Tong Zhang; Yini Qin; Xinyue Zeng; Boyu Jin; Jiahong Wang; Zixin Deng; Xuemin Song; Wenqing Chen
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Biosynthesis of vanillin glucoside in Escherichia coli在大肠杆菌中合成香草醛葡糖苷
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IF4.4
delete2026-09-08
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deleteMingyu Tian; Jinyi Li; Yong Du; Xiaolin Shen; Jia Wang; Xinxiao Sun; Qipeng Yuan
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Ribosome engineering enhances genetic code expansion in Saccharomyces cerevisiae核糖体工程增强酿酒酵母中的遗传密码扩展
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-08-29
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deleteXiaoxu Chen; Wenlu Shen; Xianqing Chen; Fangfang Zhang; Bo Yang; Zhiyong Yue; Guanghou Zhao
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Deep learning-driven de novo design of ribosome binding sites in Paracoccus denitrificans深度学习驱动的反硝化假单胞菌核糖体结合位点从头设计
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IF4.4
delete2026-08-13
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deleteZhiping Zheng; Shenghu Zhou; Yu Deng
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Unlocking raw-corncob consolidated bioprocessing for malic acid production by DyP-enabled lignin deconstruction in Myceliophthora thermophila通过嗜热毛霉中DyP介导的木质素解聚技术，释放原始玉米芯整合生物加工生产苹果酸
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IF4.4
delete2026-08-08
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deleteYuying Zhang; Yuhan Zhang; Likun Han; Jia Liu; Defei Liu; Tao Sun; Depei Wang; Ming Li; Jingen Li; Chaoguang Tian
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Alternative splicing-induced thioesterase domain deficiency drives the production of natural orsellinic acid derivatives with a pantetheine moiety in nonreducing polyketide synthases可变剪接诱导的硫酯酶结构域缺陷驱动非还原型聚酮合酶中含泛酰巯基乙胺基团的天然奥塞林酸衍生物的产生
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-08-07
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deleteQingpei Liu; Liwei Zhou; Yifu Gong; Xinqiong Liu; Jiajie Ma; Wei Liu; Haiyan Fu; Xiaolong Yang
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Systematic evaluation of the DNA repair machinery facilitated the development of efficient genome editing tools for the red yeast Rhodotorula toruloides对红酵母Rhodotorula toruloides DNA修复机制的系统评价促进了高效基因组编辑工具的开发
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-08-06
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deleteQiongqiong Chen; Liting Lyu; Shuang Wang; Zongbao K. Zhao
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Toward engineered microbial chassis for growth–production balancing构建用于生长-生产平衡的工程微生物底盘
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IF4.4
delete2026-08-06
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deleteHuanghui Xia; Bingmei Wang; Feng Qi; Jianzhong Huang
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EINN: An enzyme-informed neural network guided by an enzyme-constrained genome-scale metabolic modelEINN：一种由酶约束的基因组规模代谢模型指导的酶信息神经网络
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IF4.4
delete2026-08-06
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deleteRay Steven; Kai Kimata; Denis Chegodaev; Lilies Handayani; Kenji Satou
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Characterization of two key cytochrome P450 enzymes in Isodon amethystoides and de novo production of 3a,15(3-dihydroxy-ent-kaurene in yeast青蒿中两种关键细胞色素P450酶的表征及在酵母中从头生产3a,15(3-二羟基-ent-贝壳杉烯
deleteSynthetic and Systems Biotechnology
IF4.4
delete2026-08-01
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deleteChen, Yanying; Song, Xinqi; Wang, Yanan; Han, Yang; Xia, Meng; Yuan, Shijun; Ma, Ying; Wang, Jian; Ma, Qing; Liu, Shuang; Su, Ping; Huang, Luqi
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