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ACS Chemical Neuroscience 封面图

ACS Chemical Neuroscience

IF3.9
论文数4637
被引数12933
期刊论文 4637
发表时间
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Mechanistic Characterization of NABi as a Selective Inhibitor of SOD1G93A Aggregation: Structural Basis and Therapeutic Implications for ALSNABi作为SOD1G93A聚集选择性抑制剂的机理表征：结构基础及其对ALS的治疗意义
deleteACS Chemical Neuroscience
IF3.9
delete2026-09-02
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PREAI
deleteMin-Kyung Nam; Yeram Oh; Yemi Choi; Jieun Lee; Gi Heon Jeong; Sangjun Park; Seung-Ah Yoo; Moonseok Kim; Seongman Kang; Hyangshuk Rhim
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Development of Novel Pegylated Imidazobenzodiazepines Targeting α5 GABAA Receptors for Anxiety: A Comparative Prodrug and Metabolite Study新型聚乙二醇化咪唑苯二氮䓬类靶向α5 GABAA受体抗焦虑药物的研发：一种比较前药和代谢物的研究
deleteACS Chemical Neuroscience
IF3.9
delete2026-09-02
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deleteMubaraq A. Toriola; Ethan T. Kowalczyk; Kayode M. Medubi; Michelle J. Meyer; Maya R. T. Fernando; Petra Scholze; Nethyanji Premananda; Shaun G. Harrington; Braden R. Barkley; Daniel A. Webb; Leggy A. Arnold
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Development and Preclinical Evaluation of a Novel PET Probe for Phosphodiesterase 7B Imaging in Brain新型磷二酯酶7B脑成像正电子发射断层扫描探针的开发与临床前评估
deleteACS Chemical Neuroscience
IF3.9
delete2026-09-02
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deleteTomoteru Yamasaki; Zhiwei Xiao; Masayuki Fujinaga; Wakana Mori; Yiding Zhang; Jian Rong; Katsushi Kumata; Zhendong Song; Yusuke Kurihara; Haofeng Shi; Masanao Ogawa; Jiyun Sun; Nobuki Nengaki; Taoqian Zhao; Tomomi Kokufuta; Kazui Nakamoto; Lin Xie; Yinlong Li; Steven H Liang; Ming-Rong Zhang
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Body Temperature and Discriminative Stimulus Effects of Nicotine and Menthol Aerosols in Male Rats: Role of α4β2 Nicotinic Acetylcholine Receptors体温和辨别性刺激效应：尼古丁和薄荷醇气溶胶在雄性大鼠中的作用——α4β2烟碱乙酰胆碱受体
deleteACS Chemical Neuroscience
IF3.9
delete2026-09-02
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deleteTae In Eom; Pill-Kyu Jang; Jiyun Nam; Suji Kim; Bong Hyo Lee; Suchan Chang; Hye Jin Cha; Jaesuk Yun; Chae Ha Yang; Sooyeun Lee; Seong Shoon Yoon
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Phage Display-Derived Cyclic Peptides Target TREM2 and Modulate Microglial Responses Under Amyloid Stress噬菌体展示衍生的环肽靶向TREM2并在淀粉样蛋白应激下调节小胶质细胞反应
deleteACS Chemical Neuroscience
IF3.9
delete2026-08-19
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PREAI
deleteNatalie Fuchs; Shaoren Yuan; Katarzyna Kuncewicz; Mohamed Atta Elhamouly; Farida El Gaamouch; Moustafa T. Gabr
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G2019S LRRK2 Kinase Inhibition in Heterozygous Mice Avoids Lung Phenotype Observed with Inhibition of WT LRRK2G2019S LRRK2激酶在杂合子小鼠中的抑制作用避免了与WT LRRK2抑制相关的肺表型
deleteACS Chemical Neuroscience
IF3.9
delete2026-08-05
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deleteAlbert W. Garofalo; Marcus D. Schonemann; Matteo Santoro; Jing Zhao; R. Jeremy Nichols; Thomas J. Montine
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Modulating Stress Granules via HDAC6 Inhibition: A Promising Strategy against Alzheimer’s Disease通过HDAC6抑制调节应激小体：一种对抗阿尔茨海默病的有前景策略
deleteACS Chemical Neuroscience
IF3.9
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deleteEmona Jagaselvan; Prasenjit Mondal; Can Zhang
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Serotonin Deficits Modulate Hippocampal Plasticity5-羟色胺缺乏调节海马可塑性
deleteACS Chemical Neuroscience
IF3.9
delete2026-07-08
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deleteRocío B. Foltran; Mariano Soiza-Reilly
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Structure–Property Relationship Analysis of α-Keto Ester Prodrugs of Monomethyl Fumarate as NRF2 Activatorsα-酮酸酯类单甲基富马酸前药作为NRF2激活剂的构效关系分析
deleteACS Chemical Neuroscience
IF3.9
delete2026-07-07
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deleteDamian L. Stachura; Fátima Rivera-Escalera; Dion J. L. Turner; Mohd S.U. Rasheed; David M. Ruiz; Thomas D. Avery; Anibal R. Davalos; R. Jason Herr; Peter M. Grace; Andrew D. Abell
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Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons发现VU6077564：一种选择性M1拮抗剂，可促进成年感觉神经元轴突生长
deleteACS Chemical Neuroscience
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deleteTomayo I. Berida; Cayden J. Dodd; Joshua C. Wilkinson; Darrell R. Smith; Sichen Chang; Christopher C. Presley; Li Peng; Snehal Sant; Srinivasan Krishnan; Irene Zagol-Ikapitte; Katherine J. Watson; Analisa Thompson Gray; Alice L. Rodriguez; Hyekyung P. Cho; Carrie K. Jones; Olivier Boutaud; Colleen M. Niswender; Darren W. Engers; Paul Fernyhough; Craig W. Lindsley; Elizabeth S. Childress
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The Effect of Cu2+ and Zn2+ Ions’ Nonbonded Interactions on the Aggregation of β-Amyloid 1–16 and 25–35 Fragments─A Molecular Dynamics Simulation StudyCu2+和Zn2+离子非键相互作用对β-淀粉样蛋白1–16和25–35片段聚集的影响─分子动力学模拟研究
deleteACS Chemical Neuroscience
IF3.9
delete2026-07-06
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deleteRayla Kelly Magalhães Costa; Felipe Rodrigues Souza; Rudielson dos Santos Silva; Nicolás A. Rey; Andre Silva Pimentel
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Coordinated Subpocket Engagement Underlies Nitazene Potency at the μ-Opioid Receptor协同亚口袋结合是氮杂吲哚类阿片类药物在μ-阿片受体上发挥作用的基础
deleteACS Chemical Neuroscience
IF3.9
delete2026-07-05
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deleteMargaret Jane Robinson; Li Chen; Abhishek Thakur; Kuo-Hao Lee; Lei Shi
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Quantitative Assessment of Neurometabolism by Deuterium and Proton NMR Spectroscopy Using [6; 6′-2H2]Glucose利用[6; 6′-2H2]葡萄糖通过氘和质子NMR波谱学对神经代谢进行定量评估
deleteACS Chemical Neuroscience
IF3.9
delete2026-07-02
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deleteAkila Ramesh; Ravinder Reddy; Anant Bahadur Patel
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NLX-112; a Selective 5-HT1A Receptor Agonist; Upregulates GDNF and is Neuroprotective Against MPTP-Induced Nigrostriatal Degeneration in a Mouse Model of Parkinson’s DiseaseNLX-112；一种选择性5-HT1A受体激动剂；上调GDNF，并在帕金森病小鼠模型中对抗MPTP诱导的黑质纹状体变性发挥神经保护作用
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deleteWilliam H. Powell; Lucy E. Annett; Ronan Depoortere; Adrian Newman-Tancredi; Mahmoud M. Iravani
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Bithiophene Scaffold for PET Imaging and Photosensitization as a Novel Theranostic Platform Targeting Amyloid-β Aggregates双噻吩骨架用于正电子发射断层成像和光敏化，作为靶向淀粉样β聚集的新型诊疗平台
deleteACS Chemical Neuroscience
IF3.9
delete2026-06-30
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deleteTakahiro Akasaka; Hiroyuki Watanabe; Masahiro Ono
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Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects低激动活性和平衡通路调节区分了一种缺乏胆碱能不良反应的M1毒蕈碱受体正向别构调节剂
deleteACS Chemical Neuroscience
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delete2026-06-30
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deleteHuong T. M. Nguyen; Elham Khajehali; Vi Pham; John W. Scott; Toby A. Dite; Laura F. Dagley; James M. Murphy; Geoff Thompson; Andrew B. Tobin; David M. Thal; Arthur Christopoulos; Emma T. van der Westhuizen; Celine Valant
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Imaging Synaptic Vesicle Protein SV2C with 18F-UCB-F: An In Vitro Autoradiography and In Vivo NHP PET Study使用18F-UCB-F成像突触囊泡蛋白SV2C：一项体外放射自显影和体内非人灵长类动物PET研究
deleteACS Chemical Neuroscience
IF3.9
delete2026-06-26
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deleteS. Nag; V. C. Sousa; R. Zou; A. F. Morén; P. Datta; Y. Khani; A. Valade; C. Vermeiren; P. Motte; J. Mercier; H. Ågren; C. Halldin; A. Varrone
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UBOX5 Modulates the Cognitive Dysfunction by Degrading HSP70 Protein in Sleep-Deprived Mice泛素结合域蛋白5通过降解热休克蛋白70调节睡眠剥夺小鼠的认知功能障碍
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IF3.9
delete2026-06-25
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deleteGuoshao Zhu; Changsheng Su; Zhenming Kang; Yangyi Li; Jianchuan Lin; Yadi Zhang
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Involvement of Raphe Nuclei in Depressive-like Behaviors and Short-Term Memory in an Animal Model of Parkinson’s Disease中缝核在帕金森病动物模型中抑郁样行为和短期记忆中的作用
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deleteDaniele C. Ramos; Jeane C. F. Vieira; Leonardo C. Souza; Mariza Bortolanza; Elaine Del Bel; Roberto Andreatini; Maria A. B. F. Vital
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Comprehensive Evaluation of Indazole-Based Synthetic Cannabinoid Receptor Agonists with Aliphatic Tail Groups: In Vitro Activities; Metabolic Stability; and In Vivo Pharmacokinetics基于吲唑的合成大麻素受体激动剂（含脂肪族尾基）的综合评价：体外活性、代谢稳定性和体内药代动力学
deleteACS Chemical Neuroscience
IF3.9
delete2026-06-24
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deleteThuy Nguyen; Vineetha Vasukuttan; Lucas Laudermilk; Dharshini Ganeshan; Elaine Gay; Katie Hale; Samuel Banister; Julie Marusich; Michelle Glass; Rangan Maitra; Yanan Zhang
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