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European Journal of Medicinal Chemistry Reports 封面图

European Journal of Medicinal Chemistry Reports

IF4.1
论文数371
被引数626
期刊论文 371
发表时间
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Affinity Selection-Mass Spectrometry Discovery of Small Molecule ILT3 (LILRB4) Binders and Pharmacological Characterization in Alzheimer’s Disease Models亲和选择-质谱法发现小分子ILT3（LILRB4）结合物及其在阿尔茨海默病模型中的药理学表征
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-10-28
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deleteSomaya A. Abdel-Rahman; Natarajan Arul Murugan; Moustafa T. Gabr
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Chemical modification of indirubin reveals a mitochondrial vulnerability and overcomes multidrug resistance in leukemia cells靛红红化学修饰揭示了白血病细胞中线粒体易损性并克服多药耐药性
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-10-26
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deleteJohanna Rueter; Franziska Bannwart; Sebastian Bieringer; Jennifer Witt; Jerico Frias; Corazon Frias; Holger N. Lode; Herbert Riepl; Aram Prokop
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Synthesis, α-glucosidase inhibition, and antidiabetic evaluation of 2-phenylquinoline-indole hydrazine hybrids: In vitro, in vivo, and computational studies2-苯基喹啉-吲哚酰肼类化合物的合成、α-葡糖苷酶抑制活性及抗糖尿病评价：体外、体内及计算研究
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-10-16
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deleteAshkan Khademi; Anahita Alimoradpour; Somayeh Mojtabavi; Hassan Mohammadi; Fahimeh Ghasemi; Bagher Larijani; Mohammad Mahdavi; Mina Saeedi
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Design, synthesis, and biological activity studies of novel iron-chelating hybrids targeting pathological pathways associated with Alzheimer's disease新型铁螯合杂化物的设计、合成及其针对与阿尔茨海默病相关病理通路生物学活性的研究
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-10-14
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deleteCamille Nguyen; Firas El Kadiry; Quentin Muziot; Marc Maresca; Cédric Spitz; Sylvia Pietri
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“Design, Synthesis, and Biological Evaluation of Novel Oxindole-Based Derivatives as Potent and Selective Antileukemic Agents.”“基于恶唑烷酮衍生物的设计、合成及其作为强效且选择性抗白血病剂的生物活性评价。”
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-10-07
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deleteMuhamad Mustafa; Aya Soudi; Petr Dzubak; Sona Gurska; Ivo Frydrych; Marian Hajduch; Burak Tüzün; Ibrahim M. Salem; Tarek S. Ibrahim; Michael Smietana; Jean-Yves Winum; Omar M. Aly; Taha F.S. Ali; El-Shimaa M.N. Abdelhafez
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Synthesis, structure, photophysical, photochemical, and biological properties of hybrid macrocyclic structures containing two naphthalene moieties and a tri(ethylene glycol) tether含两个萘基和一个三(乙二醇)连接基团的杂合大环结构的合成、结构、光物理、光化学和生物性质
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-09-17
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deleteMarco Paolino; Jacopo Venditti; Gabriele Manenti; Mario Saletti; Alessandro Donati; Claudia Bonechi; Germano Giuliani; Chiara Botta; Stefania Lamponi; Valerio Ciccone; Maria Frosini; Sandra Donnini; Lucia Morbidelli; Riccardo Carletti; Filippo Sacchetta; Andrea Cappelli
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Coumarin-based phytochemicals decursin, osthole, and scoparone as new lead compounds for cerebrovascular protection in ischemic stroke基于香豆素的植物化学物质 Decursin、Osthole 和 Scoparone 作为缺血性脑卒中脑血管保护的新先导化合物
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-09-15
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deleteMehdi Valipour
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Synthesis, anti-cancer activity, Pim-3 inhibitory potency and zebrafish larvae toxicity evaluation of indolopyrazolocarbazole derivatives吲哚吡唑咔唑衍生物的合成、抗肿瘤活性、Pim-3抑制活性和斑马鱼幼体毒性评价
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-09-02
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deleteThéo Frazier; Elisabeth Pereira; Reidun Aesoy; Andrea Trentani; Francis Giraud; Lars Herfindal; Fabrice Anizon; Pascale Moreau
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Pyrazoline- and Hydrazone-Linked Thiazole-Triazole Hybrids as Potent Dual-Stage Antileishmanial Agents with Antifolate Activity吡唑并-和肼基-连接的噻唑-三唑杂合物作为具有抗叶酸活性的强效双阶段抗利什曼原虫剂
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IF4.1
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deleteEsraa A. Abdelsalam; Wagdy M. Eldehna; Sherif F. Hammad; Nicolas Masurier; Tamer M. Ibrahim; Kikuko Amagase; Sherry N. Nasralla; Yara E. Mansour; Hatem A. Abdel-Aziz; Adnan A. Bekhit; Radwan El-Haggar
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The multifunctional therapeutic potential of Dermaseptin S4 and its analogs: A comprehensive review of structure, mechanisms, and biomedical applications德马杀菌肽S4及其类似物的多功能治疗潜力：结构、机制和生物医学应用的全面综述
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IF4.1
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deleteAlireza Neshani; Mehdi Nabati Moghaddam; Mohammad Sadegh Damavandi
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Small-molecule ferroptosis modulators in oncology: Design principles, evidence standards, and translational opportunities
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-08-12
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deleteTania Ciaglia; Valeria Napolitano; Francesca Di Matteo; Alessia Bertamino; Isabel Maria Gomez Monterrey
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Design, synthesis and antibacterial evaluation of amphiphilic 1,2,4-oxadiazole-based pyridinium salts两亲性1,2,4-噁二唑基吡啶盐的设计、合成及抗菌活性评价
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IF4.1
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deleteSara Amata; Virginia Talarico; Gaspare Crisà; Giuseppe Pizzolanti; Andrea Pace; Antonio Palumbo Piccionello; Cinzia Calà; Carla Rizzo
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Discovery and pharmacological evaluation of a novel series of chromenopyrazole-based GPR55 modulators in an androgen-driven model of female metabolic dysfunction基于色烯吡唑的新型GPR55调节剂的发现及药理学评价：在雄激素驱动的女性代谢功能障碍模型中
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IF4.1
delete2026-08-06
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deleteFrancisco J. Ponce-Díaz; Francisco Ruiz-Pino; Aitor Herraiz; Beatriz Romero; Laura Cerero-Tejero; Adela García-Martín; Simon Porzio-Gonzalez; Paula Morales; Miguel A. Sánchez-Garrido; Marina Pulido; Nadine Jagerovic; Manuel Tena-Sempere; Eduardo Muñoz
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Rational design of 3,4,5-trimethoxyphenyl-phenoxy-triazole derivatives as highly potent α-glucosidase inhibitors3,4,5-三甲氧基苯基-苯氧基-三唑衍生物的合理设计作为高活性α-葡萄糖苷酶抑制剂
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IF4.1
delete2026-08-05
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deleteShahab Kermaninia; Morteza Farina; Mohammad Mahdavi; Aida iraji
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Small-molecule antibacterials and resistance-modifying agents小分子抗菌剂和耐药性修饰剂
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
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PREAI
deleteZelisko, Nataliya; Kovalenko, Iryna; Lesyk, Danylo; Vilenskyi, Andrii; Lavryk, Galyna; Rumynska, Tetyana; Zubach, Olena; Lesyk, Roman
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Integrative in silico and experimental identification of non-covalent UBE2N inhibitors enhancing PARP inhibitor sensitivity通过计算和实验相结合的方法鉴定能够增强PARP抑制剂敏感性的非共价UBE2N抑制剂
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-07-30
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deleteCôme Ghadi; Shafi Ullah Khan; Léonie Ibazizene; Florian Schwalen; Charline Kieffer; Peggy Suzanne; Julie Jaouen; Hassiba Bouafia; Xavier Thuru; Marie Cornu; Cedric Lecoutey; Matthieu Meryet-Figuiere; Anne Sophie Voisin-Chiret; Louis-Bastien Weiswald; Jana Sopkova-de Oliveira Santos
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New C-30 secondary and tertiary amines of betulin with selective antiproliferative activity toward hematological malignancies - Synthesis and biological evaluation具有选择性抗增殖活性的桦木酸C-30仲胺和叔胺衍生物——合成与生物活性评价
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IF4.1
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deleteJan Bachořík; Ivo Frydrych; Soňa Gurská; Štěpán Dostál; Jan Pokorný; Adam Přibylka; Martina Medvedíková; Petr Džubák; Marián Hajdúch; Milan Urban
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Marine natural products for antifungal drug discovery: An updated review (2015–2025)海洋天然产物在抗真菌药物发现中的应用：更新综述（2015–2025）
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deleteSalma A. Haggag; Ahmed K. ElHady; Nardine Adel; Mirna Y. Abouomar; Abdelrhman M. Shoman; Ebaa M. El-Hossary; Ashraf H. Abadi; Usama Ramadan Abdelmohsen; Tsong-Long Hwang; Mohammad Abdel-Halim
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A MCC950 analogue inflammasome inhibitor reduces the foreign body reaction against neural implantsMCC950类似物炎症小体抑制剂减轻神经植入物的异物反应
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-07-10
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deleteJose Crugeiras; Chiara Bisquoli; María Rodríguez-Brañas; Bruno Rodríguez-Meana; Tiziano De Ventura; Neus Hernández; Jessica Jaramillo; Alice Honovich; Ignacio Delgado-Martínez; Natalia Lago; Hanna Karlsson-Fernberg; Maria Asplund; Stefano Carli; Claudio Trapella; Giulia Turrin; Xavier Navarro
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Beyond arginine count: Rational engineering of amphipathic macrocyclic CPPs with enhanced intracellular delivery and endosomal escape超越精氨酸计数：具有增强的细胞内递送和内涵体逃逸功能的两亲性大环CPPs的理性设计
deleteEuropean Journal of Medicinal Chemistry Reports
IF4.1
delete2026-07-04
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deleteDuc Tai Nguyen; Michael Desgagné; Ulrike Froehlich; Andréanne Laniel; Christine Lavoie; Pierre-Luc Boudreault
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