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Recent Patents on Anti-Cancer Drug Discovery

IF4.1
论文数21
被引数1149
期刊论文 21
发表时间
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CAIX-HIF-1α Inhibition by 2-(4-Chlorophenyl)-3-(4-Ethoxyphenyl) Thiazolidin-4-one (BCS12) Activates Caspase Cascade and PARP Cleavage, Driving Mitochondrial Apoptosis in Hypoxic Breast CancerCAIX-HIF-1α被2-(4-氯苯基)-3-(4-乙氧基苯基)噻唑烷-4-酮(BCS12)抑制后激活半胱天冬酶级联反应和PARP裂解，驱动缺氧乳腺癌的线粒体凋亡
deleteRecent Patents on Anti-Cancer Drug Discovery
IF4.1
delete2026-04-01
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PREAI
deleteRanjan, Gaurav; Pattanayak, Shakti Prasad; Sunita, Priyashree
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Synergistic Antitumor Activity of DA-10 and Niraparib by Overcoming Platinum Resistance in Ovarian CancerDA-10和Niraparib通过克服卵巢癌铂耐药性产生的协同抗肿瘤活性
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IF4.1
delete2026-03-01
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PREAI
deleteYu, Ruyuan; Xu, Yingru; Tang, Miaoling; Zhang, Shengyuan; Ke, Zunfu
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Advancements in Sotorasib: A Comprehensive Review of its Efficacy in Non-small Lung Cancer Treatment索托拉西布在非小细胞肺癌治疗中的疗效进展：综合评述
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IF4.1
delete2026-02-01
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PREAI
deleteTupe, Archana; Bhosale, Sachin; Shinde, Nirmala
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Resibufogenin and Oxaliplatin Synergistically Inhibit Diffuse Gastric Cancer by Inactivating the FAK/AKT/GSK3β/β-Catenin Signaling PathwayResibufogenin和奥沙利铂通过失活FAK/AKT/GSK3β/β-catenin信号通路协同抑制弥漫性胃癌
deleteRecent Patents on Anti-Cancer Drug Discovery
IF4.1
delete2026-01-01
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PREAI
deleteHu, Hui-Hui; Shang, Hai-Li; Ren, Yongjing; Lv, Hui-Fang; Tu, Shuiping; Wang, Jian-Zheng; Gong, Ya-Nan; Li, Zhi-Fei; Zhang, He; Li, Tiepeng; Wang, Yuhang; Chen, Bei-Bei; Wang, Sai-Qi; Chen, Xiao-Bing
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Differential Expression and Distribution of Slco4a1 and Slco1b2 in an Internal Environment Disorder-induced Hepatocellular Carcinoma Mouse ModelSlco4a1和Slco1b2在内环境紊乱诱导的肝癌小鼠模型中的差异表达与分布
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IF4.1
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deleteLuo, Haoxuan; Xie, Yang; Huang, Shan; Zhang, Yu
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Effect of Oral Posaconazole on Venetoclax Plasma Concentration and its Efficacy in Patients with Acute Myeloid Leukemia口服泊沙康唑对急性髓性白血病患者中维奈克拉血浆浓度及其疗效的影响
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IF4.1
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deleteGuo, Mengqi; He, Yingzhi; Du, Jingwen; Qiu, Dezhi; Qin, Yinjie; Huang, Yuxian
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Lactylation Plays a Novel Role in the Tumor Microenvironment and its Prognostic Implications for Breast Cancer乙酰乳酰化在肿瘤微环境中的作用及其对乳腺癌的预后意义
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IF4.1
delete2026-01-01
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PREAI
deleteGao, Lili; Yao, Hongfei; Li, Qing
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A Comprehensive Review of Genistein and Chitosan: Mechanistic Foundations, Regulatory Roadmap, and Future Research Directions大豆苷元和壳聚糖的综合综述：机制基础、监管路线图和未来研究方向
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IF4.1
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deleteAdhikari, Bishop; Venkatesh, D. Nagasamy; Puri, Vivek; Sharma, Ameya; Nayak, Prashant; Ahmed, Syed Suhaib
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Covalent Inhibitor Screening for Targeting LOXL2: Studied by Virtual Screening and Experimental Validation靶向LOXL2的共价抑制剂筛选：通过虚拟筛选和实验验证进行研究
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IF4.1
delete2026-01-01
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deleteLin, Lirui; Lin, Kai; Chen, Lichun; Wang, Yiwen; Xu, Li-Yan; Li, En-Min; Liu, Qingping; Zou, Haiying; Dong, Geng
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Patent Landscape and Technological Trajectory of Drug Delivery Systems for Overcoming Drug Resistance in Non-small Cell Lung Cancer非小细胞肺癌耐药性药物递送系统的专利格局与技术发展轨迹
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deleteWu, Feiyan; Tang, Xinglinzi; Luo, Xinyi; Li, Caizhi; Lai, Xin; Li, Danyang; Li, Hang
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Melanoma Metastasizing to the Breast: A Case Report黑色素瘤转移至乳腺：病例报告
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IF4.1
delete2026-01-01
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deletePan, Xiaocheng; Chen, Zichang; Chen, Junhong; Huang, Jiaxu; Chen, Ruipei; Luo, Gengcong; He, Junbing; Chen, Hongpeng
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Multi-omics Analysis Uncovers TFRC/HMOX1-dependent Ferroptosis Mediating Celastrol's Anti-invasive/Metastatic Effects on Esophageal Squamous Cell Carcinoma多组学分析揭示TFRC/HMOX1依赖性铁死亡介导雷公藤甲素对食管鳞状细胞癌的抗侵袭/抗转移作用
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IF4.1
delete2026-01-01
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PREAI
deleteZha, Yulong; Shen, Tao; Luo, Huayu; Zhang, Yu; Ren, Hongzheng
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Single-cell and Bulk RNA-Seq Analyses Reveal TOMM7-mediated Multi-cell Death Mechanisms Driving Muscle-invasive Bladder Cancer Progression单细胞和Bulk RNA-Seq分析揭示了TOMM7介导的多细胞死亡机制驱动肌肉浸润性膀胱癌进展
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IF4.1
delete2025-12-01
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deleteZhang, Jinge; Zheng, Li; Yu, Zhe; Chen, Yuwen; Jiang, Feifan; Zhang, Zicai; Li, Tanghua; Zhao, Hongfan; Li, Yaxian; Li, Fei
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Mir-338-3p Increases the Sensitivity to Oxaliplatin via Reversing Epithelial-mesenchymal Transition in Hepatocellular Carcinoma CellsMir-338-3p 通过逆转上皮-间质转化增加肝细胞癌细胞对奥沙利铂的敏感性
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IF4.1
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deleteHuang, Chuan; Huang, Zhenguang; Luo, Jun; Wu, Meiyi; Cai, Kaining; Zhao, Ruiqiang; Wen, Yan
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A Metastasis-competent CAF Subpopulation Defined by MFAP5+THY1+ Co-expression Drives Prostate Cancer Metastasis via EMT Activation由MFAP5+THY1+共表达定义的具有转移能力的CAF亚群通过激活EMT驱动前列腺癌转移
deleteRECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY
IF4.1
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deleteHuang, Yongqiang; Wang, Yu; Zhang, Wei; Wang, Wenfeng; Du, Leilei; Zhang, Xingming; Xu, Wenhao; Zheng, Jianghua; Shi, Guohai; Wang, Jianhua
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Mendelian Randomization Combined with Experimental Validation Identifies Prognostic Genes LMNB1 and PLXNB2 in the Immune Response in Multiple Myeloma孟德尔随机化结合实验验证在多发性骨髓瘤的免疫应答中识别出预后基因LMNB1和PLXNB2
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IF4.1
delete2025-10-01
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deleteZhang, Xiaofen; Kong, Qiuhong; Zhao, Jianhao; Qiao, Ruifang; Niu, Fei; Jia, Haipeng; Duan, Yanchao
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Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway京尼平通过HMGB1介导的PI3K/AKT/mTOR信号通路失活抑制肝癌
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IF4.1
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deleteLi, Weinan; Ma, Xuan; Mei, Yong; Peng, Cijun; Feng, Zanjie
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Tracing the Technological Trajectory of CAR-T Cell Therapy in Cancer Treatment through Patent Analysis
deleteRECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY
IF4.1
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deleteGuan, Yilan; Liu, Yunting; Sun, Yuxuan; Liu, Baijun; Yuan, Hongmei
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CAD is Associated with Cancer Prognosis and Promotes Enzalutamide Resistance in Prostate Cancer
deleteRECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY
IF4.1
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deleteMa, Bing-Xue; Mao, Yi-You; Zhang, Ze-Fan; Zeng, Xian-Zi; Xie, Xiao; Zhao, Hua; Li, Qin; Wen, Ying-Hao; Cai, Mao-Ping; Xie, Tao; Yu, Yu-Zhong; Zhao, Shan-Chao; Ren, Yang-Zi
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Advances in Artemisinin-based Therapies: Innovations in Synthesis, Drug Delivery, and Expanding Therapeutic Applications青蒿素类药物的进展：合成、药物递送及拓展治疗应用的创新
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IF4.1
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deleteThakur, Akshay; Thakur, Gaurav; Sharma, Vir Vikram; Singh, Kuldeep; Gupta, Jeetendra Kumar; Jain, Divya; Sharma, Mukesh Chandra
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