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Drug Development Research 封面图

Drug Development Research

IF4.2
论文数3276
被引数3628
期刊论文 3276
发表时间
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Exploiting Plasmodium Mitochondrial Pathways for Next-Generation Antimalarial Drug Development: Prospects and Updates利用 Plasmodium 线粒体通路开发下一代抗疟药物：前景与最新进展
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IF4.2
delete2026-10-24
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PREAI
deleteRohit Nehra; Kuldeep Singh; Himmat Singh; Praveen Kumar Bharti; Suman Dhanda
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Advancements of Emerging Thiazole-Based CDKs Inhibitors for Cancer Therapy: From Hits to Clinical Candidates新兴噻唑基CDKs抑制剂在癌症治疗中的进展：从先导化合物到临床候选药物
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IF4.2
delete2026-10-23
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PREAI
deleteMenglin Luo; Shuwang Jiang; Yufeng Ma; Peiliang Zhao
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Bavachin Attenuates Cognitive Impairment in Scopolamine‐Induced Amnesia: Behavioral, Biochemical and Molecular Insights补骨脂素减轻东莨菪碱诱导的记忆障碍：行为学、生物化学和分子机制研究
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IF4.2
delete2026-10-09
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PREAI
deleteMd. Shadin; Monisha Brati Barua; Talat Ali; Farha Farahim; Md. Ripon; Mehedi Hasan Linkon; Md. Shakil; Mohammed Alfaifi; Faisal H. Altemani; Abdullah H. Altemani; Faisal Alsenani; Muhammad Torequl Islam
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TEAD1 Knockdown Ameliorates Diabetic Erectile Dysfunction in Rats and Is Associated With Modulation of Calcium Signaling-Mediated Contractile MachineryTEAD1基因敲低可改善大鼠糖尿病勃起功能障碍，并与其调节钙信号介导的收缩机制相关
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IF4.2
delete2026-10-01
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PREAI
deleteTao Zhang; Chenxiao Wu; Youlong Lu; Weili Li; Huaru Zhang; Cheng Li
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Design, Synthesis and Molecular Docking Studies of Some Novel Hydrazone Derivatives Based on Trimetazidine as Selective and Potent AChE Inhibitors基于曲美他嗪的新型肼基化合物衍生物的设计、合成及分子对接研究：作为选择性且高效的乙酰胆碱酯酶抑制剂
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IF4.2
delete2026-10-01
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deleteMuhammed Oğuzhan Doğan; Begüm Nurpelin Sağlık Özkan; Abdullah Burak Karaduman; Sevgi Karakuş; Yusuf Özkay; Zafer Asım Kaplancıklı; Fatih Tok
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Solanaceae-Derived Spirostane Saponins Inhibit Dengue Virus Replication and Viral Protein Expression and Exhibit Activity Against Multiple Arboviruses茄科来源的螺甾烷皂苷抑制登革病毒复制和病毒蛋白表达，并对多种虫媒病毒表现出活性
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IF4.2
delete2026-10-01
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PREAI
deleteErika Vanessa Jimenez-Posada; Oscar Marino Mosquera-Martínez; Sara M. Robledo; Diego Durango; Wiston Quiñones; Samuel Vizcaíno-Páez; Marlen Martinez-Gutierrez
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Comprehensive Evaluation of Gastrointestinal Factors Influencing the Stability and Function of mRNA-Encapsulated Lipid Nanoparticles胃肠道因素对mRNA包封脂质纳米粒稳定性和功能影响的综合评价
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IF4.2
delete2026-10-01
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deleteToma Shinkai; Koki Ogawa; Mohamed S. Mohamed; Tetsuya Ozeki
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GRP78 Drives NSCLC Stemness and EMT via a SIX1/β-Catenin Signaling AxisGRP78通过SIX1/β-连环蛋白信号轴驱动NSCLC的干细胞特性和EMT
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IF4.2
delete2026-10-01
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PREAI
deleteGuoping Tong; Huanyu Qi
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Applications of Bioinorganic Nano-Based Delivery Systems—Diagnostics and Therapeutics生物无机纳米基递送系统的应用——诊断和治疗
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IF4.2
delete2026-10-01
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deleteFrank Ssengooba; Jubilee Andrew; Donald Fernandes
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Alternative Splicing in Cyclin-Dependent Kinase 4/6 Inhibitor Resistance in Estrogen Receptor-Positive Breast Cancer雌激素受体阳性乳腺癌中cyclin依赖性激酶4/6抑制剂耐药性的选择性剪接
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IF4.2
delete2026-10-01
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PREAI
deleteYuqiu Cui; Jia Xie; Jiale Cai; Yue Si; Hairong Huang; Shiyi Yu; Haibo Sun
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Molecular Design and Anticancer Activities of Small-Molecule BRAF Inhibitors: A Medicinal Chemistry Perspective小分子BRAF抑制剂的分子设计与抗癌活性：药物化学视角
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IF4.2
delete2026-09-23
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PREAI
deleteShuyu Jia; Jieman Lin; Janjun Wu; Hao Xu; Qingwei Zeng; Meipin Liu; Jiayi Shen
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Sphingosine-1-Phosphate Attenuates LPS-Induced Inflammatory Cardiac Injury in Association With RASGRP1–S100A9–NLRP3 Signaling鞘氨醇-1-磷酸通过RASGRP1–S100A9–NLRP3信号通路减轻LPS诱导的炎症性心脏损伤
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IF4.2
delete2026-09-23
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deleteChaofu Yue; Qiaolin Li; Chunyan Li; Taoxian Yang; Xian Huang; Feng Yue; Qiuyu Long; Rong Li; Rong Lei; Qingsong Ma; Caimei Hu; Qian Yang; Yongjun Yan; Yuan Liu; QinYong Yan; Mei Yang
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Statins as Repurposed Anticancer Agents: Regulated Cell Death, the Tumor Immune Microenvironment, and the Translational Evidence Gap他汀类药物作为再利用的抗肿瘤药物：调节性细胞死亡、肿瘤免疫微环境及转化证据差距
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IF4.2
delete2026-09-21
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PREAI
deleteXu Zhou; Yizhang Chen; Hanxiao Hua; Bo Shen; Shuai Liang; Dong Hua
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Comparative Evaluation of Plumbagin and Sorafenib in NDEA–TAA-Induced Hepatocellular Carcinoma: Effects on Hepatic Function, Redox Homeostasis and Histopathology比较评价铅丹和索拉非尼在NDEA–TAA诱导的肝细胞癌中的效果：对肝功能、氧化还原稳态和病理组织学的影响
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IF4.2
delete2026-09-20
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PREAI
deleteAkinade K. Adetola; Regina N. Ugbaja; Olubisi E. Adeyi; Funmilola C. Thomas; Johnson A. Adeyemo; Oluwafemi A. Odesola
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Synthesis of Tetrahydro-β-Carboline-Based Spirocyclic Peptides via Cascade N-Boc Deprotection and Pictet-Spengler Reaction of Tryptophan: Potent Anti-Inflammatory and Anti-Oxidant Activities通过色氨酸的级联N-Boc脱保护与Pictet-Spengler反应合成四氢-β-咔啉基螺环肽：具有显著的抗炎和抗氧化活性
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IF4.2
delete2026-09-17
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PREAI
deleteShravani Battula; Vaishnavi Kambhampati; Sai Balaji Andugulapati; Kiranmai Nayani
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Gypenosides Damulin A and Damulin B Inhibit Hepatocellular Carcinoma by Regulating Cholesterol Synthesis绞股蓝皂苷达莫林A和达莫林B通过调节胆固醇合成抑制肝细胞癌
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IF4.2
delete2026-09-17
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PREAI
deleteFang-Fang Li; Can Cui; Zhou-Juan Zheng; Man-Yu Xiao; Si Li; Peng Xie; Xiang-Lan Piao
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Design, Synthesis, In Vitro Biological Evaluation, and In Silico Studies of Novel Imidazo[4,5-b]Pyridine-Acrylonitrile-Based Derivatives as VEGFR-2 Inhibitors Against Breast Cancer and Hepatocellular Carcinoma新型咪唑[4,5-b]吡啶-丙烯腈基衍生物的设计、合成、体外生物评价及计算机模拟研究：作为抗乳腺癌和肝细胞癌的VEGFR-2抑制剂
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IF4.2
delete2026-09-16
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PREAI
deleteLamia W. Mohamed; Ahmed A. Saadeldin; Ayman B. Farag
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Advances in N- and S-Heterocycles as c-Jun-N-Terminal Kinase 3 Inhibitors for Alzheimer's Disease TreatmentN-和S-杂环在阿尔茨海默症治疗中作为c-Jun-N端激酶3抑制剂的进展
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IF4.2
delete2026-09-16
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PREAI
deleteParul Yadav; Deepak Mishra; Ram Singh
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Psychotropic Drugs: A Promising Non-Antibiotic Agent to Combat Multi-Drug-Resistant Microorganisms精神类药物：一种有前景的非抗生素药物，用于对抗多药耐药微生物
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IF4.2
delete2026-09-09
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PREAI
deleteIndu Singh; Haritima Singh; Divakar Sharma; Anushri Keshri; Naveen Gaurav; Megh Singh Dhakad; Mirza Masroor Ali Beg
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Anticancer Potential of Antimicrobial Peptides: Mechanisms, Clinical Application, Challenges, and Future Prospects抗菌肽的抗癌潜力：机制、临床应用、挑战与未来展望
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IF4.2
delete2026-09-08
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PREAI
deleteQiang Zhang; Shengjun Li; Zhen Wang; Xu Qiu; Xingmiao Yang; Shuai Li; Zheng Gong; Bin Wang; Bei Zhang; Li Zhang
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