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Artificial Intelligence in the Life Sciences

IF5.4
论文数26
被引数365
期刊论文 26
发表时间
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Reprogramming cancer therapeutics through artificial intelligence-guided drug repurposing: Computational innovation, experimental validation, and translational challenges通过人工智能指导的药物重定位重新编程癌症疗法：计算创新、实验验证和转化挑战
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IF5.4
delete2026-06-01
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deleteFawzy, Marola Paula; Nafie, Mohamed S.; Nabih, Nadine Wafik; Diab, Mohamed K.; Babker, Asaad; Mohamed, Hatem; Hassan, Hatem A. F. M.; Fahmy, Sherif Ashraf
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Can we reliably identify drug targets at the proteome scale using AlphaFold based docking or generative AI?能否可靠地利用AlphaFold基的对接或生成式AI在蛋白质组规模上识别药物靶点？
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IF5.4
delete2026-04-01
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PREAI
deleteXing, Xiaodong; Guo, Yi; Wang, Ting; Fu, Yuan
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PATHOS: Predicting variant pathogenicity by combining protein language models and biological featuresPATHOS: 结合蛋白质语言模型和生物学特征预测变异致病性
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IF5.4
delete2026-03-01
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deleteRadjasandirane, Ragousandirane; Cretin, Gabriel; Diharce, Julien; de Brevern, Alexandre G.; Gelly, Jean-Christophe
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The comfort of automation: why cognitive sovereignty matters in AI-driven life sciences自动化带来的舒适：人工智能驱动的生命科学中认知主权的重要性
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IF5.4
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deleteBranda, Francesco; Ciccozzi, Massimo
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Understanding biology with machine learning: compression, intelligibility, and dependency利用机器学习理解生物学：压缩、可解释性及依赖性
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deleteLawrence, Elsa; El-Shazly, Adham; Seal, Srijit; Joshi, Chaitanya K.; Lio, Pietro; Bender, Andreas; Singh, Shantanu; Sormanni, Pietro; Spjuth, Ola; Greenig, Matthew
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Long short-term memory-based chemical language models for bioactive molecular generation using tailored pre-training datasets基于长短期记忆网络的化学语言模型，使用定制预训练数据集进行生物活性分子生成
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deleteAbe, Ryuto; Miyao, Tomoyuki
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Drug sensitivity prediction across cancer cell lines with a focus on sarcoma肉瘤肿瘤细胞系中的药物敏感性预测
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deleteXerxa, Elena; Koch, Selina; Vanni, Silvia; De Vita, Alessandro; Bajorath, Jurgen
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Integrating clinical evidence for multi-condition care整合多病症护理的临床证据
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deleteGupta, Endri; Anand, Astha; Hofmann-Apitius, Martin; Jacobs, Marc
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CDTA: Consistency-based deep learning method for drug-target affinity prediction using sequential features from protein language modelCDTA：基于一致性的深度学习方法，利用蛋白质语言模型的序列特征进行药物-靶点亲和力预测
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deleteCader, Jiffriya Mohamed Abdul; Newton, M. A. Hakim; Sattar, Abdul
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CLOVER: A framework for benchmarking synthetic data generation methods balancing utility and privacy in healthcareCLOVER：一个用于平衡医疗保健领域效用与隐私的合成数据生成方法基准测试框架
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deleteQi, Yue; Herbault, Lorrie; Lautraite, Hadrien; Yu, Michael; Blanchet, Katleen; Vincelette, Christian; Mullie, Louis; Dumas, Guillaume; Rajotte, Jean-Francois; Gambs, Sebastien; Afzali, Kamran; Chasse, Michael
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Development of a deep neural network model for simultaneous analysis of extracellular analyte gradients for a population of cells开发用于同时分析细胞群体胞外分析物梯度分布的深度神经网络模型
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deleteAcosta-Ramirez, Ivon; Sadak, Ferhat; Das Choudhury, Sruti; Thomson, James; Perez-Rosero, Salome; Plange, Portia N. A.; Morales-Mendivelso, Sofia E.; Iverson, Nicole M.
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The time dimension matters: Improving mode of action classification with live-cell imaging☆时间维度很重要：利用活细胞成像改进作用模式分类
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deleteForsgren, Edvin; Rietdijk, Jonne; Holmberg, David; Juneblad, Julia; Migliori, Bianca; Johansson, Martin M.; Carreras-Puigvert, Jordi; Trygg, Johan; Lovell, Gillian; Spjuth, Ola; Jonsson, Par
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SynthFormer: Equivariant pharmacophore-based generation of synthesizable molecules for ligand-based drug designSynthFormer：基于等变药效团的合成分子生成方法，用于基于配体的药物设计
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deleteJocys, Zygimantas; Zhu, Zhanxing; Willems, Henriette M. G.; Farrahi, Katayoun
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A client-enhanced language model for interactive compound optimization guided by explainable artificial intelligence基于可解释人工智能引导的交互式化合物优化客户增强语言模型
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deleteYoshimori, Atsushi; Bajorath, Jurgen
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Implementing XAI in life sciences: Key challenges and pathways to solutions在生命科学中实现可解释人工智能：关键挑战与解决方案途径
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deleteKrejcar, Ondrej; Abdullah, Jamaluddin; Namazi, Hamidreza
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Leveraging artificial intelligence and koch snowflake fuzzy sets to optimize antibiotic development pathways利用人工智能和科赫雪花模糊集优化抗生素开发路径
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delete2025-12-01
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deleteEti, Serkan; Yuksel, Serhat; Eti, Secil Topaloglu; Dincer, Hasan; Eyupoglu, Ozan Emre
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Hallucinations in medical devices (vol 8, 100145, 2025)医疗设备中的幻觉 (vol 8, 100145, 2025)
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deleteGranstedt, Jason; Kc, Prabhat; Deshpande, Rucha; Garcia, Victor; Badano, Aldo
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A crossover-enhanced Marine Predators Algorithm for gene selection in microarray-based cancer classification一种交叉增强的Marine Predators Algorithm用于基于微阵列的癌症分类中的基因选择
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deleteMakhadmeh, Sharif Naser; Sanjalawe, Yousef; Al-Betar, Mohammed Azmi; Nasayreh, Ahmad; Aladaileh, Mohammad
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Unraveling the co-morbidity between COVID-19 and neurodegenerative diseases through multi-scale graph analysis: A systematic investigation of biological databases and text mining通过多尺度图分析揭示COVID-19与神经退行性疾病共病关系：一项对生物数据库和文本挖掘的系统研究
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deleteBabaiha, Negin Sadat; Geissler, Stefan; Nibart, Vincent; Guevenilir, Heval Atas; Bharadhwaj, Vinay Srinivas; Kodamullil, Alpha Tom; Klein, Juergen; Jacobs, Marc; Hofmann-Apitius, Martin
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Hallucinations in medical devices医疗器械中的幻觉
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delete2025-11-01
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deleteGranstedt, Jason; Kc, Prabhat; Deshpande, Rucha; Garcia, Victor; Badano, Aldo
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