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Chemical Biology and Drug Design 封面图

Chemical Biology and Drug Design

IF3.3
论文数3446
被引数6423
期刊论文 3446
发表时间
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Antidiabetic Evaluation of New Pyrimidine-Thiazoline Hybrids Endorsed With Enzyme Kinetic Studies and Computational Analysis抗糖尿病评价：新型嘧啶-噻唑啉杂化物的酶动力学研究及计算分析
deleteChemical Biology & Drug Design
IF3.3
delete2025-12-23
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deleteOAAI
deleteGobind Kumar; Pule Seboletswe; Neha Manhas; Safiyah Ghumran; Nontobeko Gcabashe; Gaurav Bhargava; Almahi Idris; Md. Shahidul Islam; Parvesh Singh
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Design, Synthesis, Computational Modeling and Biological Evaluation of Novel N-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)cinnamamides as Potential Covalent Inhibitors for Oncology设计、合成、计算建模及生物评价作为潜在共价抑制剂的 Novel N-(7H-吡咯并[2,3-d]嘧啶-4-基)肉桂酰胺类化合物用于肿瘤学
deleteChemical Biology & Drug Design
IF3.3
delete2025-12-06
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PREAI
deleteRameshwar S. Cheke; Prashant S. Kharkar
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Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole-Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs合成、细胞毒性活性及分子对接研究：含噻唑基的新型 indenopyridazine 衍生物作为潜在的抗增殖药物
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-11
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PREAI
deleteAlaa M. Alqahtani; Sultan I. Alkbaysi; Mariam Mojally; Amgad Albohy; Hussni Muathen
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Design of Hybrid Bioactive Peptides Derived From Cecropin and Cathepsin for Therapeutic Application基于Cecropin和Cathepsin的杂交生物活性肽的药物应用设计
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-07
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deleteGabriele Santos Cepinho; Bruna Vitória Scavassa; Gabrielle L. de Cena; Vitor Martins de Andrade; Luís Roberto F. Lima; André Zelanis; Montserrat Heras; Miguel A. R. B. Castanho; Katia Conceição
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Protein Kinase Inhibitors: Synthesis and Molecular Repurposing in Three-Dimensional Cancer Models PKI蛋白激酶抑制剂：合成与三维肿瘤模型中的分子重定位 PKI
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-06
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PREAI
deleteVladislav Lobanov; Natalia Rossomakhina; Elena Kazakova; Victoria Zherdeva; Vadim Makarov
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Madecassoside Induces Apoptosis and Inhibits Migration by Regulating ROS-Mediated Signaling Pathways in MDA-MB-231 Breast Cancer CellsMadecassoside 通过调节 ROS 介导的信号通路诱导 MDA-MB-231 乳腺癌细胞凋亡并抑制其迁移
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-06
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PREAI
deleteWen-Shuang Hou; Ying-Hua Luo; Nan Wu; Yan-Jun Tang; Yan-Zhi Liu; Yan-Liang Zhang; Cheng-Hao Jin
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Investigation Into the Inhibition of Ferroptosis by Praeruptorin-A in Sepsis Based on Network Pharmacology基于网络药理学探究Praeruptorin-A对脓毒症中铁死亡抑制作用的调查
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-06
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deleteYue-Ming Chen; Jing-Jing Pan; Fu-Ping Lyu; Ke-Ying Wu; Jia-Jie Jing; Qi-an He; Bo-Han yu; Yu-Hui Ma; Dong-Yang Guo
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Sulfonyl Hydrazone Derivatives Targeting Glutathione Reductase: A Potential Strategy for Redox Modulation in Cancer靶向谷胱甘肽还原酶的磺酰基 hydrazone 衍生物：癌症氧化还原调控的一种潜在策略
deleteChemical Biology & Drug Design
IF3.3
delete2025-11-04
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deleteErbay Kalay; Halide Sedef Karaman; Osman Nuri Aslan; Feyzi Sinan Tokalı; Muhammet Karaman; Musa Erdoğan
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Molecular Mechanism of Dexmedetomidine in Alzheimer's Disease: Machine Learning Identifies RGS7 as a Key Therapeutic Targe右美托咪定在阿尔茨海默病中的分子机制：机器学习识别RGS7为关键治疗靶点
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-31
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deleteYangliang Yang; Anjun Xu; Pengcheng Xie; Jingli Yang
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Synthesis and Molecular Modeling Studies of New Thiadiazole-Thiophene Compounds as Potent Antimicrobial Agents新型噻二唑-噻吩化合物的合成与分子建模研究及其作为强效抗菌剂的应用
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IF3.3
delete2025-10-31
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deleteNuha M. Halawani; Fatimah A. Alotaibi; Omer A. Azher; Arwa Alharbi; Nadiyah M. Alshammari; Asmaa L. Alanzy; Nawaa A. H. Alshammari; Nashwa M. El-Metwaly
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Antiproliferative Activity and Target Analysis of 18β-Glycyrrhetinic Acid Derivatives Modified With α, β-Unsaturated Carbonyl Groups18β-甘草次酸衍生物经α, β-不饱和羰基基团修饰后的抗增殖活性与靶点分析
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-31
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deleteChenmeng Xu; Yi Li; Na Wang; Rui Wang; Jianjun Huang; Deshang Li; Qianqian Wang; Jingyu Liu; Bo Wang; Ruofan Chen; Wim Dehaen; Qiyong Huai
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Design and Synthesis of 2-Aminopyrazolpyrimidopyridone Derivatives as RETV804M and RETG810C Kinase Inhibitors2-氨基吡唑嘧啶吡啶酮衍生物的设计与合成及其作为RETV804M和RETG810C激酶抑制剂的研发
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IF3.3
delete2025-10-31
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deleteJiayi Shen; Anzhi Li; Jieman Lin; Jihu Liu; Shuyu Jia; Xu Zhao; Sheng Chen; Yongdong Li
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Coumarin-Containing Aromatic Sulfonamides With Carbonic Anhydrase Inhibitory Properties Against Human and Fungal Isoforms含香豆素的芳香磺酰胺类化合物，具有抑制人源和真菌源碳酸酐酶异构体的性质
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-29
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deleteAndrea Angeli; Anthi Petrou; Victor Kartsev; Viviana De Luca; Clemente Capasso; Athina Geronikaki; Claudiu T. Supuran
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Ginkgolide B Combined With Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Alleviate Diabetic Nephropathy by Modulating the Nuclear Factor Erythroid-2-Related Factor 2/Heme Oxygenase 1 Pathway银杏内酯B与脐带间充质干细胞来源的外泌体通过调节核因子Erythroid-2相关因子2/血红素加氧酶1通路缓解糖尿病肾病
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-29
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PREAI
deleteFang Zhong; Wentong Zheng; Mingjian Peng
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Exploring the Mechanisms of Resveratrol in ARDS Treatment: From Network Pharmacology and Molecular Docking to In Vitro Validation探索白藜芦醇在ARDS治疗中的机制：从网络药理学和分子对接到体外验证
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-23
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PREAI
deleteZhili Zhang; Wanting Hu; Xixi Cong; Junjie Zhang; Siyu Sun; Meng Qin; Weiping Zhang; Ying Yu
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Potential Mechanism of Qiju Dihuang Pill in Treating Primary Sjogren's Syndrome Revealed by Network Pharmacology and Experimental Verification网络药理学及实验验证揭示的杞菊地黄丸治疗原发性舍格伦综合征的潜在机制
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-21
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deleteHuiying Wang; Hui Cheng; Mei Li; Xiaofang Zhu; Xiaobing Wang
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Deep Learning for Drug–Target Interaction Prediction: A Comprehensive Review深度学习方法用于药物-靶点相互作用预测：综述
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-21
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deleteYingjun Chen; Ding Luo; Weiwei Xue
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Skullcapflavone II Suppresses Colorectal Cancer by Inhibiting the HIF-1α-Glycolysis PathwaySkullcapflavone II通过抑制HIF-1α-糖酵解通路抑制结直肠癌
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-21
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PREAI
deleteShiwei Yang; Wenqi Hu; Xuezhi Xin; Guang Zhang
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Dl-3-n-Butylphthalide Inhibits Autophagy to Alleviate the Neuronal Apoptosis After Spinal Cord Injury by Elevating YAP via Inactivating the Hippo Signaling PathwayDL-3-n-丁基邻苯二甲酰亚胺通过失活Hippo信号通路升高YAP来抑制自噬，以缓解脊髓损伤后的神经元凋亡。
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-17
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PREAI
deleteShengsen Yang; Wenbo Gu; Zhongtang Ma; Ruobing Guo
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Advances in the Molecular Mechanism of Kappa Opioid Receptors Signaling and the Important Sampling Methods to Probe the Activation Landscape of GPCRsκ阿片受体信号传导的分子机制进展及探查GPCRs激活景观的重要采样方法
deleteChemical Biology & Drug Design
IF3.3
delete2025-10-14
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PREAI
deleteMingqiong Tong; Wan Sun; Pingxuan Dong; Jinghe Wang; Xiangling Gu; Zanxia Cao
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