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Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2 (vol 31, pg 1243, 2017) 铁氧还蛋白还原酶通过铁调节蛋白2（vol 31, pg 1243, 2017）对p53依赖性肿瘤抑制至关重要 Zhang, Yanhong; Qian, Yingjuan; Zhang, Jin; Yan, Wensheng; Jung, Yong-Sam; Chen, Mingyi; Huang, Eric; Lloyd, Kent; Duan, Yuyou; Wang, Jian; Liu, Gang; Chen, Xinbin 分享 收藏
Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness 白血病突变蛋白PHF6和PHIP形成一个染色质复合物，该复合物抑制急性髓系白血病干性。 Pawar, Aishwarya S.; Somers, Patrick; Alex, Aleena; Grana, Jason; Feist, Victoria K.; George, Subin S.; Jalnapurkar, Sapana S.; Antony, Charles; Verner, Roman; White-Brown, Sanese K.; Khera, Mohit; Mendoza-Figueroa, Maria Sarai; Liu, Kathy Fange; Morrissette, Jennifer J. D.; Gurbuxani, Sandeep; Paralkar, Vikram R. 分享 收藏
A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change 一项全基因组CRISPR筛选揭示了驱动脂肪细胞命运转变过程中翻译起始和泛素化新的需求。 Turn, Rachel E.; Hilgendorf, Keren I.; Johnson, Carl T.; Han, Kyuho; Aziz-Zanjani, Mohammad Ovais; Bollinger, Samuel Swails; Domizi, Pablo; Cheng, Ran; Rabiee, Atefeh; Zhu, Yingdi; Jiang, Zewen; Asthana, Anushweta; Demeter, Janos; Svensson, Katrin J.; Bassik, Michael C.; Jackson, Peter K. 分享 收藏
SUMO2 promotes histone pre-mRNA processing by stabilizing histone locus body interactions and facilitating U7 snRNP assembly SUMO2通过稳定组蛋白基因座体相互作用并促进U7 snRNP的组装来促进组蛋白前体mRNA的加工。 He, Shuying; Lyu, Pin; Skinner, Marnie W.; Desotell, Anthony; Foley, Brendan; McCaig, Chance M.; Wang, Wei; Qian, Jiang; Tong, Liang; Marzluff, William F.; Matunis, Michael J. 分享 收藏
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate 组蛋白载体与DNA复制和转录偶联，调控异质染色质元件以维持细胞命运 Franklin, Reuben; Zhang, Brian; Frazier, Jonah; Chen, Meijuan; Do, Brian T.; Padayao, Sally; Wu, Kun; Vander Heiden, Matthew G.; Vakoc, Christopher R.; Ninova, Maria; Murn, Jernej; Sykes, David B.; Cheloufi, Sihem 分享 收藏
CDK4 loss-of-function mutations cause microcephaly and short stature CDK4功能缺失突变导致小头畸形和身材矮小 Verdu Schlie, Aitana; Leitch, Andrea; Arismendi, Maria Izabel; Stok, Colin; Castro Leal, Andrea; Parry, David A.; Lerario, Antonio Marcondes; Harley, Margaret E.; Lucheze, Bruna; Carroll, Paula L.; Musialik, Kamila I.; Auer, Julia M. T.; Martin, Carol-Anne; Gerasimavicius, Lukas; Quigley, Alan J.; Correia-Deur, Joya Emilie de Menezes; Marsh, Joseph A.; Reijns, Martin A. M.; Lampe, Anne K.; Jackson, Andrew P.; Jorge, Alexander A. L.; Tamayo-Orrego, Lukas 分享 收藏
MRN-CtIP, EXO1, and DNA2-WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage MRN-CtIP、EXO1和DNA2-WRN/BLM在PARPi处理细胞中无链断裂的情况下，双向作用处理DNA间隙。 Seppa, Isabelle M.; Ceppi, Ilaria; Tennakoon, Mithila; Reginato, Giordano; Jackson, Jessica; Rouault, Celia D.; Agashe, Sumedha; Sviderskiy, Vladislav O.; Limbu, Mangsi; Lantelme, Erica; Meroni, Alice; Braunshier, Stefan; Borrello, Damiano; Verma, Priyanka; Cejka, Petr 分享 收藏
Cognition and behavior in neurofibromatosis type 1: report and perspective from the Cognition and Behavior in NF1 (CABIN) Task Force 神经纤维瘤病1型的认知与行为：Cognition and Behavior in NF1 (CABIN)工作组报告与展望 Gutmann, David H.; Anastasaki, Corina; Gupta, Aditi; Morris, Stephanie M.; Payne, Jonathan M.; Raber, Jacob; Tomchik, Seth M.; Van Aelst, Linda; Walker, James A.; Yohay, Kaleb H. 分享 收藏
Developmentally regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation MdfA和ClpCP介导的发育调控蛋白酶解作用调控枯草芽孢杆菌(Bacillus subtilis)芽孢形成过程中的代谢分化。 Riley, Eammon P.; Lyda, Jelani A.; Reyes-Matte, Octavio; Sugie, Joseph; Kasu, Iqra R.; Enustun, Eray; Armbruster, Emily G.; Ravishankar, Sumedha; Isaacson, Rivka L.; Camp, Amy H.; Lopez-Garrido, Javier; Pogliano, Kit 分享 收藏
MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore MdfA是一种新型的ClpC适配器蛋白，在发育中的*枯草芽孢杆菌*孢子中发挥作用。 Massoni, Shawn C.; Evans, Nicola J.; Hantke, Ingo; Fenton, Colleen; Torpey, James H.; Collins, Katherine M.; Krysztofinska, Ewelina M.; Muench, Janina H.; Thapaliya, Arjun; Martinez-Lumbreras, Santiago; Ferrell, Se Hart; Slater, Celia; Wang, Xinyue; Fekade, Ruth; Obwar, Sandra; Yin, Siyu; Vazquez, Alishba; Prior, Christopher B.; Turgay, Kuersad; Isaacson, Rivka L.; Camp, Amy H. 分享 收藏
Active telomere elongation by a subclass of cancer-associated POT1 mutations 由一类与癌症相关的POT1突变引起的端粒主动延长 Martin, Annika; Schabort, Johannes; Bartke-Croughan, Rebecca; Tran, Stella; Preetham, Atul; Lu, Robert; Ho, Richard; Gao, Jianpu; Jenkins, Shirin; Boyle, John; Ghanim, George E.; Jagota, Milind; Song, Yun S.; Li, Hanqin; Hockemeyer, Dirk 分享 收藏
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