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J

Journal of Pharmacological and Toxicological Methods

IF1.8
论文数103
被引数2295
期刊论文 103
发表时间
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The emerging use of artificial intelligence in safety pharmacology and toxicology人工智能在安全药理学和毒理学中的新兴应用
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-06-01
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PREAI
deleteMiller, Lutfiya; Treleaven, Ian; El Amrani, Abdel-Ilah; Rossman, Eric I.; Winters, Brett R.; Pugsley, Michael K.
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Special Issue of Journal of Pharmacological and Toxicological Methods: Cutting edge pharmacological and toxicological methods《药理学与毒理学方法杂志》特刊：前沿药理学与毒理学方法
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-03-01
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deleteTabrizchi, Reza; Daneshtalab, Noriko
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Analytical method development for detection and quantification of AMB-FUBINACA in mouse brain tissue using GC-MS/MS使用GC-MS/MS检测和定量小鼠脑组织中AMB-FUBINACA的分析方法开发
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-03-01
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PREAI
deleteAl-Qudsi, Jihad; Alghamdi, Malak; Bakdash, Abdulsallam; Abdelgadir, Elkhatim H.; Baggi, Tulsidas R.; Kumar, Sachil
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QbD-based, greenness and whiteness-assessed LC-MS/MS method for simultaneous determination of sodium phenylbutyrate and Taurursodiol with pharmacokinetic application基于QbD、绿色性和白度评估的LC-MS/MS方法同时测定苯基丁酸钠和Taurursodiol及其药代动力学应用
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
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deletePalla, Thirumalavasu; Maddala, Venkata Kanaka Srivani; Gandla, Kumaraswamy
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Streamlined dispersive solid phase extraction for determination of amitriptyline, cocaine, and benzoylecgonine in urine
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-03-01
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deleteGaletti, Isabela Nucci; Luz, Heloisa Peres; da Silva, Bruna Espindola; Perin, Maite; Marchioni, Camila
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Study on pharmacokinetic behaviors of colchicine sustained-release microspheres in beagle dogs and its relevance to toxicity mitigation via LC-MS/MS比格犬中秋水仙碱缓释微球的药代动力学行为研究及其通过LC-MS/MS降低毒性的相关性
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-02-01
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deleteYang, Chuyao; Wang, Jingtao; Zhang, Qiannan; Wang, Yuli; Wang, Lingchao; Zhang, Wenpeng; Xu, Jinghua; Zhuang, Xiaomei
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The chicken embryo model as a tool for investigating drug-induced acute kidney injury鸡胚模型作为研究药物诱导急性肾损伤的工具
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-01-01
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deleteBernardi, Murillo D. L.; den Ouden, Krista; Nieuwenhuijzen-Van de Kaa, Melanie; Nguyen, Vivian V. T.; Schutgens, Frans; Verhaar, Marianne C.; Rookmaaker, Maarten B.; van Balkom, Bas W. M.
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An accurate and reproducible method to measure snake venom anticoagulant activity一种准确且可重复的方法用于测量蛇毒抗凝活性
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2026-01-01
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deleteMurphy, Kate; Tasoulis, Theo; Isbister, Geoffrey K.
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Analytical method validation with development for the detection and quantification of kratom alkaloids using LC-MS/MSRashid, M.H.; O’Croinin, C.; Le, T.S.; Abdi, Z.; Loebenberg, R.; Davies, N.M. 采用LC–MS/MS技术检测和定量 kratom 碱类化合物的分析方法开发与验证。J. Pharmacol. Toxicol. Methods 2026, 137, 108409. [Google Scholar] [CrossRef]
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
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deleteRashid, Md Harunur; O'Croinin, Conor; Le, Tyson S.; Abdi, Zeinab; Loebenberg, Raimar; Davies, Neal M.
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Rapid quantification of CSF total protein via smartphone digital colorimetry: Enabling early diagnosis of central nervous system diseases通过智能手机数字比色法快速定量测定脑脊液总蛋白：实现中枢神经系统疾病的早期诊断
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deleteZhao, Yonghua; Liang, Dandan; Guo, Yufei; Li, Ziqi; Yang, Zehua
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An ex vivo zebrafish heart model for oxidative stress studies离体斑马鱼心脏模型用于氧化应激研究
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IF1.8
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deleteWu, Yong; Zhang, Huiqi; Sun, Fengnian; Zhang, Wantong; Jiang, Ziyun
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LC-MS/MS-based simultaneous quantification of chlorthalidone and cilnidipine in rat plasma: Pharmacokinetic evaluation, green analytical assessment, and DoE-driven optimization基于LC–MS/MS的氯噻酮和cilnidipine在大鼠血浆中的同时定量：药代动力学评价、绿色分析评估及DoE驱动的优化
deleteJournal of Pharmacological and Toxicological Methods
IF1.8
delete2025-12-01
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deleteGandu, Sravanthi; Gandla, Kumaraswamy; Repudi, Lalitha
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PolyCheck: A hybrid model for predicting polypharmacy-induced adverse drug reactions in tuberculosis treatment using heterogenous drug-target-ADR networks (vol 136, 108393, 2025)PolyCheck：一种利用异构药物-靶点-ADR网络预测结核病治疗中药物联合使用所致不良反应的混合模型（卷136，108393，2025）
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deleteGhafari, Ahmad Tamim; Zakaria, Yuslina; Hasan, Mizaton Hazizul; Majeed, Abu Bakar Abdul; Nazari, Qand Agha
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Effects of alendronate and vitamin D on plasma metabolomic profiles in a rat model of osteoporosis阿仑膦酸钠和维生素D对骨质疏松症大鼠模型血浆代谢组谱的影响
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deleteHamza, Amel; Wishart, David; Doschak, Michael R.
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A novel, flexible, and accessible method for the ex vivo induction and quantification of excitotoxicity一种新颖的、灵活的且易于操作的方法，用于体外的兴奋毒性诱导和定量分析
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IF1.8
delete2025-10-01
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deleteCarew, Samantha J.; Kennedy, Christiana M.; Greenland, Meghan L.; Parsons, Matthew P.
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Non-clinical cardiovascular safety testing: Current status, gaps and emerging trends
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IF1.8
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deleteHoffmann, Peter; Pugsley, Michael K.
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Regulatory safety pharmacology & toxicology assessment studies: Measurement of the ECG and hemodynamic parameters in nonrodent species安全性药理学与毒理学评价研究：非啮齿类物种的心电图和血流动力学参数测量
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IF1.8
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deleteValentina, Jean-Pierre; Bourcierb, Todd; Chib, Xuan; Delaunoisa, Annie; Foleyc, C. Michael; Hendersond, Kim A.; Laineee, Pierre; Leishmanf, Derek J.; Lig, Dingzhou Dean; Pawluka, Emma; Pugsleyh, Michael K.; Rajamanii, Sridharan; Reganj, Christopher P.; Rolfk, Michael G.; Rossmanl, Eric I.; Rossm, Rebecca; Tichenorn, Stephen D.; Vargasd, Hugo M.; Moask, Immaculada C.; Wisialowskig, Todd A.; Wub, Jean
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Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation重新评估ICH S7A核心组中的安全性药理学呼吸研究：一项多公司评估，评估其非临床效用和临床转化
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IF1.8
delete2025-09-01
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deleteKremer, John J.; Abernathy, Matt M.; Ackley, David; Clark, Matthew; Dasilva, Jamie K.; Foley, Michael C.; Greiter-Wilke, A.; Henderson-Park, Kim H.; Morimoto, Bruce H.; Paglialunga, Sabina; Pugsley, Michael K.; Regan, Chris P.; Rossman, Eric I.; Segretti, Jason A.; Traebert, Martin; Vargas, Hugo M.; Wisialowski, Todd A.; Friedrichs, Greg S.
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Advancing personalised treatment selection for atrial fibrillation: An in silico approach推进房颤个性化治疗方案选择：一种计算机模拟方法
deleteJOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
delete2025-09-01
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deleteMisghina, Semhar B.; Rauseo, Elisa; Lopez-Barrera, Carlos E.; Vigmond, Edward J.; Slabaugh, Gregory; Aung, Nay; Petersen, Steffen E.; Munroe, Patricia B.; Roney, Caroline H.
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PolyCheck: A hybrid model for predicting polypharmacy-induced adverse drug reactions in tuberculosis treatment using heterogenous drug-target-ADR networksPolyCheck：一种利用异构药物-靶点-ADR网络预测结核病治疗中药物联合使用引发的不良药物反应的混合模型
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IF1.8
delete2025-09-01
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deleteGhafari, Ahmad Tamim; Zakaria, Yuslina; Hasan, Mizaton Hazizul; Majeed, Abu Bakar Abdul; Nazari, Qand Agha
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