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Molecular Therapy Nucleic Acids

IF6.1
论文数1404
被引数13224
期刊论文 1404
发表时间
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Development of a G-Quadruplex-Forming DNA Aptamer Against EGFR-Driven Malignancies针对EGFR驱动的恶性肿瘤的G-四链体形成DNA适配体的开发
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-28
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deleteDeepa Singh; Vikas Kumar; Akash Kumar; Tushar Kushwaha; Than Dar Aung; Kamal Baswal; Rajkumar Kulandaisamy; Manoj Kumar; Saroj Kumar; Prabhat Singh Malik; Tailor Prafullakumar; Deepak Seghal; Tarun Kumar Sharma; Mohan Babu Appaiahgari; Krishna K. Inampudi
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Allele-selective and pan-allelic huntingtin lowering differentially affect neuronal homeostasis and BDNF transport选择性等位基因和全等位基因亨廷蛋白降低对神经元稳态和BDNF运输产生差异影响
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-27
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deleteRomane A. Lahaye; Aude Lemesle; Laurent Cotter; Donya El Akrouti; Virginie Redeker; Mathilde Louçã; Hélène Jean-Jacques; Yuanjing Liu; Abbie Maguire; Naoki Iwamoto; Michael Byrne; Chandra Vargeese; Sophie Lenoir; Frédéric Saudou; Anselme L. Perrier
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Engineered Lipid Nanoparticles Can Safely and Efficiently Deliver Plasmid DNA for Hemophilia A Gene Therapy工程化脂质纳米颗粒可安全高效地递送质粒DNA用于血友病A基因治疗
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-22
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deleteMeng-Ni Fan; Ting-Yen Chao; Xiaohe Cai; Carol H. Miao
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Polymeric Nanoparticles for a Localized In Vivo Production of Therapeutic Antibodies聚合物纳米粒子用于体内局部生产治疗性抗体
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-22
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deleteFrea Maddalena; Durigutto Paolo; Dal Bo Michele; Macor Paolo
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Targeting the provirus in HIV-1 latently infected cells with a cell-activation inducible CRISPR-Cas9 system: an in vitro proof of concept利用细胞激活诱导的CRISPR-Cas9系统靶向HIV-1潜伏感染细胞中的前病毒：体外概念验证
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-22
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deleteGloria Magro; Carolina Tarabella; Alfredo Garzino-Demo; Marta Trevisan; Giorgio Palù; Valentina Poletti; Roberto Galizi; Arianna Calistri; Cristina Parolin
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Development and validation of potent, chemically stabilized, PARP1-selective siRNAs for in vivo gene silencing开发并验证高活性、化学稳定且PARP1选择性的siRNA用于体内基因沉默
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-22
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deleteBruktawit Maru; Monika M. Kojic; Raymond Furgal; Ashley Summers; Kathryn Monopoli; Anastasia Khvorova; Hassan H. Fakih; Maureen McKeague
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Replicating vs. Non-Replicating RNA Therapeutics: Mechanisms, Trade-Offs, and Future Directions复制型与非复制型RNA治疗药物：机制、权衡与未来方向
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-21
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deleteMin-Hsuan Lin; David Harrich
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The LiCO Platform: A Novel Benzimidazole-Based Lipid Conjugate for Versatile and Sustained siRNA Delivery Beyond the LiverLiCO平台：一种基于苯并咪唑的脂质偶联物，用于肝脏外多种且持续的小干扰RNA递送
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-21
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deleteMoorim Kang; Zubao Gan; Qifeng Ding; Wei-Hsiang Lin; Jie Wang; Feifei Xu; Xiaojie Zhou; Ke Lu; Vera Huang; Long-Cheng Li
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Predicting the Impact of Phosphorothioate Chirality on the Structure and Function of Oligonucleotide Therapeutics预测硫代磷酸酯手性对寡核苷酸疗法结构和功能的影响
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-21
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deleteAkanksha Manghrani; Robert G. Brinson; Christina Bergonzo
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Development of a whole-blood assay for assessing innate immune activation induced by RNA-targeting therapeutics开发一种用于评估RNA靶向治疗药物诱导的固有免疫激活的全血检测方法
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-15
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deleteFederica Grasso; Agata Famà; Francesco Coppolino; Giuseppe Valerio De Gaetano; Luca Tavella; Annamaria Petrungaro; Eugenia Quartarone; Giuseppe Teti; Concetta Beninati; Germana Lentini
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Development of antiviral LNA gapmers targeting functional stem-loop structures in tick-borne flavivirus genomes靶向蜱传黄病毒基因组功能性茎环结构的抗病毒LNA Gapmer的开发
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-15
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deleteShunsuke Okamoto; Mizuki Fukuta; Yuji Fujii; Minato Hirano; Yusuke Echigoya; Kentaro Yoshii
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Preclinical sustained analgesia and translational potential of AAV-encoded CaV3.2 peptide aptamers for peripherally targeted pain therapyAAV编码的CaV3.2肽适体在靶向外周镇痛治疗中的临床前持续镇痛作用和转化潜力
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-14
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deleteSeung Min Shin; Brandon Itson-Zoske; Xiaolin Wu; Seung-Keun Hong; Yongsong Cai; Fan Fan; Hongwei Yu
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Messenger RNA Vaccines and Beyond: Molecular Design, Delivery Platforms, and Emerging Therapeutic Applications信使RNA疫苗及其应用：分子设计、递送平台及新兴治疗应用
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-14
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deleteKyung-Soo Lee; Jun-Young Park; Chang-Ung Kim
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Selection and Characterization of ssDNA Aptamers Targeting Tick-Borne Encephalitis Virus Particles靶向蜱传脑炎病毒颗粒的ssDNA适配体的选择与表征
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-12
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deleteYuji Fujii; Tomohiro Shinozaki; Minato Hirano; Mizuki Fukuta; Taiichi Sakamoto; Kentaro Yoshii
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Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage长链非编码RNA EPB41L4A-AS1的过表达诱导流产绒毛外细胞和胎盘组织中代谢重编程
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-09
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deleteYuanchang Zhu; Qing Liu; Meijian Liao; Lianghui Diao; Tonghua Wu; Weijie Liao; Ziqiang Wang; Bing Li; Shikuan Zhang; Songmao Wang; Weidong Xie; Yuyang Jiang; Naihan Xu; Yong Zeng; Burton B. Yang; Yaou Zhang
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Orthogonal spectroscopic assessment of higher-order structure of nucleic acids and its concentration-dependent polymorphism核酸高级结构及其浓度依赖性多态性的正交光谱评估
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-07
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deleteTaiji Oyama; Satoko Suzuki; Ken-ichi Akao; Kazunori Ikebukuro; Kohsaku Kawakami; Tomohiko Yamazaki
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LncRNA Lockd promotes cardiomyocyte proliferation via Eno1/beta-catenin/Myc axis长链非编码RNA Lockd通过Eno1/β-连环蛋白/Myc轴促进心肌细胞增殖
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IF6.1
delete2026-10-07
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deleteShakti Prakash; Samprikta Kundu; Ayushi Devendrasingh Chaudhary; Sakshi Chaudhary; Chandan Kumar; Sunaina Kumari; Sandhya Singh; Babita Yadav; Anuj Kumar; Vm Prajapati; Kumaravelu Jagavelu; Shailesh Kumar; Shashi Kumar Gupta
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Aptamers without SELEX: de novo design from protein structure in hours无SELEX的适配体：基于蛋白质结构的小时级de novo设计
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-07
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deleteVladislava A. Dolgusheva; Iosif V. Leibin; Natalia O. Kudryashova; Artem R. Mukanov; Ivan I. Kuznetsov; Artem L. Manasyan; Gleb A. Pavlyuk; Ivan V. Mishkorez; Anna M. Keremet; Pavel R. Podlesnyi; Alexey N. Kalinkin; Kirill S. Avdeev; Maxim D. Kuznetsov; Nikita O. Parfenov; Stanislav M. Gromov; Dmitry Ufaev; Shamsudin S. Nasaev
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Gene transfer of microRNA-181a alleviates senescence and apoptosis in tendinopathic tenocytesmicroRNA-181a基因转移减轻肌腱病成纤维细胞的衰老和凋亡
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-05
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deleteYuh-Ruey Kuo; Che-Chia Hsu; Han-Po Tseng; Jou-Hua Wang; I-Ming Jou; Shih-Yao Chen; Po-Ting Wu
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Gene Therapy Approaches for Hereditary Neuromuscular Diseases遗传性神经肌肉疾病的基因治疗策略
deleteMolecular Therapy Nucleic Acids
IF6.1
delete2026-10-05
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deleteXue Zhang; Jiahao Wu; Yanjiang Zheng; Yifei Li; Kaiyu Zhou
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