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Clinical Pharmacology and Therapeutics

IF5.5
论文数18350
被引数19410
期刊论文 18350
发表时间
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Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization基于生理学驱动的序贯性群体模型对白蛋白趋势和 vedolizumab 药代动力学的建模，用于妊娠期给药方案优化
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-12-14
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deleteOAAI
deleteZrinka Duvnjak; Robin Michelet; Casper Steenholdt; Ella S.K. Widigson; Cæcilie Skejø; João A. Abrantes; Wilhelm Huisinga; Mette Julsgaard; Charlotte Kloft
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Navigating the Genetic Risk of Chemotherapy-Induced Hearing Loss in the Stria Vascularis在血管纹中导航化疗诱导性听力损失的遗传风险
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-12-05
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deleteTara Lazetic; Deanne Nixie R. Miao; Britt I. Drögemöller; Alain Dabdoub; Julia M. Abitbol
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Real-World Effectiveness and Safety of Recombinant Human Follicle-Stimulating Hormone (rhFSH) in Infertile Women undergoing Assisted Reproductive Technology (ART): A Korean Nationwide Cohort Study重组人促卵泡激素（rhFSH）在不孕女性中接受辅助生殖技术（ART）治疗的真实世界有效性与安全性：一项韩国全国性队列研究
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-12-02
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deleteJoong Yeup Lee; Eun-Young Choi; Jung Ryeol Lee; Young Sik Choi; Ji Hyang Kim; Chang-Woo Choo; Yunju Choe; Hee-Jin Seo; Hyesung Lee; Yujeong Shin; Yejin Jeon; Ju-Young Shin; Hoon Kim
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Long-Read Sequencing Enhances Pharmacogenomic Profiling by Resolving Complex Haplotypes, Novel Star Alleles, and Structural Variants长读长测序通过解析复杂单倍型、新型星号等位基因和结构变异，增强了药物基因组学分析。
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-27
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PREAI
deleteSumudu Rangika Samarasinghe; Andrea Gaedigk; Jesse J. Swen; Henk-Jan Guchelaar; Shivashankar H. Nagaraj
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Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post-Kala-Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing利福平阿莫地喹在HIV阳性患者中的药代动力学和药效学：潜在影响和临床意义
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-25
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deleteWan-Yu Chu; Om Prakash Singh; Shyam Sundar; Dinesh Mondal; Krishna Pandey; Pradeep Das; Ignace C. Roseboom; Sheeraz Raja; Ana Torres; Eugenia Carrillo; Alwin D.R. Huitema; Fabiana Alves; Thomas P.C. Dorlo
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Endpoint Exposure-Response Analyses in the Presence of Concurrent Dose Modification During Clinical Trials终点暴露-反应分析：临床试验期间存在同期剂量调整的情况
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-25
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PREAI
deleteRui Zhong; Yanguang Cao
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Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers突破壁垒：作为健康志愿者中血管渗漏可控诱导的体内模型，皮内脂多糖挑战的特征描述
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-15
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deleteMarella Cornelia Elizabeth van Ruissen; Menno van Diemen; Liza Botros; Ingrid Tomljanovic; Hind Achbo; Dimitra Eleftheriou; Paul Willem Schenk; Naomi Bertine Klarenbeek; Derek William Gilroy; Manon Aleida Adriana Jansen; Matthijs Moerland
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Cystatin C-based eGFR better predicts renal vancomycin clearance than creatinine-based eGFR in patients with allogeneic stem cell transplantation基于Cystatin C的eGFR比基于肌酐的eGFR更能预测异基因干细胞移植患者的万古霉素清除率。
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-12
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deleteEva-Maria A. Wansing; Sebastian G. Wicha; Peter Bannas; Alexander Heitkamp; Adrin Dadkhah; Nicolaus M. Kröger; Isabel Molwitz; Claudia Langebrake
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Enhancing Severe Neutropenia Prediction: PKPD-Informed Labeling for Machine Learning Models Trained on Real-World Data增强严重中性粒细胞减少症预测：基于真实世界数据训练的机器学习模型的PKPD信息标记
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-10
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deleteConor J O’Hanlon; Jonas Denck; Elif Ozkirimli; Stefanie Bendels; Candice Jamois; Clarisse Chavanne; Dirk Fey; Kimmo Porkka; Oscar Brück; Ken Wang
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Home Is Where the Research Is: The Promise of Decentralized Clinical Trials家是研究的港湾：去中心化临床试验的潜力
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-09
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deleteSarah A. Holstein
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Drug-Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes药物诱导的QT间期延长：瑞典临床决策支持系统中风险分类与临床结局的关联
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-09
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deleteOla Nordqvist; Olof Björneld; Patrick Bergman; Björn Wettermark; Alisa Lincke; Marine L. Andersson; Tora Hammar
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Respiratory Disorders Associated with Antibody–Drug Conjugates: A Combined Analysis of the French and the WHO Pharmacovigilance Databases抗体偶联药物相关呼吸系统疾病：法国和WHO药物警戒数据库的联合分析
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-07
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PREAI
deleteVictor Mirleau; Alex Hlavaty; Etienne-Marie Jutant; Florence Hennegrave; Kévin Bihan; Romane Freppel; Clément Cholle; Delphine Bourneau-Martin; Claire Lafay-Chebassier; Julien Mahé; Matthieu Bainaud; Marion Allouchery
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Evolving Standards: Good Clinical Practice Insights from US FDA, MHRA UK, and Health Canada演变的标准：来自美国FDA、英国MHRA和加拿大卫生部的良好临床实践见解
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-05
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PREAI
deleteCheryl Grandinetti; Mandy Budwal-Jagait; Hocine Abid; Emily Gebbia; Elena Boley; LaKisha Williams; Andrew Fisher; Leigh Marcus; Laurie Muldowney; Jenn Sellers; Jason Wakelin-Smith; Kassa Ayalew
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Insights Into Aldosterone Regulation Through Pharmacokinetic–Pharmacodynamic Modeling of an Aldosterone Synthase Inhibitor通过醛固酮合成酶抑制剂的药代动力学–药效动力学建模探究醛固酮调控
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-05
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PREAI
deleteJaviera Cortés-Ríos; William J. Jusko
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Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease模型指导的深度Q网络在指导儿童克罗恩病英夫利昔单抗给药中的应用
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-05
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deleteKei Irie; Phillip Minar; Jack Reifenberg; Brendan M. Boyle; Joshua D. Noe; Jeffrey S. Hyams; Tomoyuki Mizuno
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Toward a More accurate, Evidence-Based Classification of CYP Inhibitors: A Critical Appraisal of Current Systems迈向更准确、基于证据的CYP抑制剂分类：对当前系统的批判性评估
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-04
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deleteJanne T. Backman
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Dual Minimal Physiologically Based Pharmacokinetic Model of Tenofovir Alafenamide and Its Metabolites in Humans人类中替诺福韦艾拉酚胺及其代谢物的双最小生理药代动力学模型
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-11-03
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PREAI
deleteWeihua Jiang; Sukyung Woo
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Model-Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia基于模型的新药研发支持在慢性肾病伴贫血患者中设计个体化给药方案（Daprodustat）
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-10-31
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deleteKelly M. Mahar; Shuying Yang; Brendan Johnson; Sandra A.G. Visser; Paul van den Berg; Martijn van Noort; Teun M. Post
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Biomarker Utilization for Regulatory Decision Making: A Landscape Analysis of Neurological Drug Products Approved by FDA (2008–2024)生物标志物在监管决策中的应用：FDA（2008–2024）批准的神经类药物产品分析综述
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-10-30
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PREAI
deleteDahee Jung; Sreedharan Sabarinath; Ramana Uppoor; Mehul Mehta; Yifei Zhang
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A Fast Path from Innovation to Safe and Effective Medicine从创新到安全有效药物的快速路径
deleteClinical Pharmacology & Therapeutics
IF5.5
delete2025-10-28
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deletePeter Arlett; Falk Ehmann; Ralf Herold; Evdokia Korakianiti; Pierpaolo Moscariello; Liese Barbier; Iordanis Gravanis; Frank Pétavy; Emmanuel Cormier; Andrew Thomson; Spiros Vamvakas; Steffen Thirstrup
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