Gladstone Institute

学者数39

论文数11

被引数0

关联论文 (11)

发表时间

Maintenance of nucleosome organization through replication and transcription counteracts aberrant coalescence of active chromatin 通过复制和转录维持核小体组织，对抗活性染色质的异常聚集

Molecular Cell

IF16.6

2026-08-17

OAAI

R. Ciaran MacKenzie Frater; Rikke Rejnholdt Jensen; Joaquim Ollé López; Valentin Flury; Jeroen van den Berg; Jonathan Humbert; Anton Bournonville; Nicolas Alcaraz; Simai Wang; Hannah J. Richter; Marty G. Yang; Qian Du; Alexander van Oudenaarden; Vijay Ramani; Nils Krietenstein; Anja Groth

Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice 人源iPSC来源的小胶质细胞移植可改善粒细胞缺乏小鼠的神经病理学和回路功能障碍

Molecular Neurodegeneration

IF17.5

2026-07-16

OAAI

Hayk Davtyan; Sarah Naguib; Yuliya Voskobiynyk; Jean Paul Chadarevian; Joia K. Capocchi; Jeannie L. Giacchino; Ghazaleh Eskandari-Sedighi; Vivianna DeNittis; Jeremy B. Ford; Ani Agababian; Jasmine Nguyen; Alina L. Chadarevian; Madison S. Sutherland; Sepideh Kiani Shabestari; Kayla Tran; Bret Holt; Alissa L. Nana; Jiasheng Zhang; Salvatore Spina; Man Ying Wong; Lea T. Grinberg; William W. Seeley; Eric Huang; Claire D. Clelland; Shiaoching Gong; Li Fan; Jeanne T. Paz; Mathew Blurton-Jones; Li Gan

Linkage disequilibrium and allelic heterogeneity explain variation in coronary artery disease risk at 9p21 across populations and reduced effect in Africans 连锁不平衡和等位基因异质性解释了9p21位点多个人群中冠状动脉疾病风险的差异以及非洲人群中的减弱效应

American Journal of Human Genetics

IF8.1

2026-07-01

PREAI

Hasan Alkhairo; Satoshi Koyama; Kruthika Iyer; Austin T. Hilliard; Pik Fang Kho; Shoa Clarke; Firdous M. Abdulwahab; Themistocles L. Assimes; Julie A. Lynch; Michèle Ramsay; Kyong-Mi Chang; Philip S. Tsao; Fowzan S. Alkuraya; Kaoru Ito; Neil Risch; Catherine Tcheandjieu

A focal ischemic stroke of the somatosensory thalamus produces persistent spontaneous pain–like behavior 丘脑躯体感觉区的局灶性缺血性卒中产生持续的自发性疼痛样行为

Neurobiology of Disease

IF5.6

2026-06-16

OAAI

Jeremy B. Ford; Olive Tambou Nzoutchoum; Jarret A. Weinrich; Debleena Chatterjee; Allan I. Basbaum; Jeanne T. Paz

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding 利用RNA触发的染色质降解靶向癌症特异性突变

Nature

IF48.5

2026-06-08

PREAI

Jingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna

Discovery of candidate therapeutic targets with Geneformer 使用Geneformer发现候选治疗靶点

Nature Protocols

IF16

2026-04-23

PREAI

Yujie Zhang; Madhavan S. Venkatesh; Christina V. Theodoris

Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering 使用跨物种retron介导的重组工程对系统发育不同的细菌进行基因组编辑

Nature Biotechnology

IF41.7

2026-04-23

PREAI

Alejandro González-Delgado; Laura Bonillo-Lopez; Milo S. Johnson; Nastassia Knödlseder; Ching-Chung Ko; Yassir Lekbach; Jee-Hwan Oh; Hemaa Selvakumar; Michael C. Wold; Zihan Yu; Virginia Aragón; Jeffrey A. Gralnick; Marc Güell; Graham F. Hatfull; Benjamin K. Keitz; Britt Koskella; Vivek K. Mutalik; Jan-Peter van Pijkeren; Seth L. Shipman

Scaling and quantization of large-scale foundation model enables resource-efficient predictions in network biology 大规模基础模型的缩放和量化可以实现网络生物学中的资源高效预测

Nature Computational Science

IF18.3

2026-03-27

OAAI

Han Chen; Madhavan S. Venkatesh; Javier Gόmez Ortega; Siddharth V. Mahesh; Tarak N. Nandi; Ravi K. Madduri; Karin Pelka; Christina V. Theodoris

REPLY 回复

jacc: basic to translational science

IF0

2026-03-23

OAAI

Tselmen Daria; Justin B. Echouffo-Tcheugui; Catherine Tcheandjieu

Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation SARS-CoV-2刺突蛋白在膜上的构象动力学揭示了 furin 裂解和 D614G 突变的空间效应

Science Advances

IF12.5

2026-03-20

OAAI

Sophie R. Shoemaker; Megan Luo; Kim-Marie A. Dam; John E. Pak; Magnus A. G. Hoffmann; Susan Marqusee

Mendelian Randomization Suggests a Causal Link Between Glycemic Traits and Thoracic Aortic Structures and Diseases 孟德尔随机化表明糖代谢性状与胸主动脉结构和疾病之间存在因果关系。

JACC: Basic to Translational Science

IF0

2025-10-31

OAAI

Tselmen Daria; Kruthika Iyer; Hasan Alkhairo; Pik Fang Kho; Ken Suzuki; Konstantinos Hatzikotoulas; Lorraine Southam; Henry J. Taylor; Xianyong Yin; Ravi Mandla; Alicia Huerta-Chagoya; William N. Rayner; Michael G. Levin; Scott M. Damrauer; Philip S. Tsao; James R. Priest; Derek Klarin; James Pirruccello; Justin B. Echouffo Tcheugui; Catherine Tcheandjieu