未登录A tiered secondary poisoning risk assessment approach to prevent unnecessary fish bioaccumulation testing of pharmaceuticals一种分层二级中毒风险评估方法,用于避免对药品进行不必要的鱼类生物累积测试
Janer, Gemma; Elmoznino, Joanne; Haner, Andreas; Maynard, Samuel K.; Reddy, Dermot; Perkins, Alison N.; Lee, Michael R.; Davidson, Todd; Li, Shibin; Nfon, Erick; Woelz, Jan; Malott, Kelli Fagan; Bramke, Irene
分享
收藏Establishment of germline-encoded antibodies during primary dengue infection初次登革热感染期间种系编码抗体的建立
Verdonckt, Thomas-Wolf; Sahulcik, Marek; Bouckaert, Johanna; Vermeersch, Anne-Sofie; Struyfs, Caroline; Van Nieuwerburgh, Filip; Waickman, Adam; Thomas, Stephen J.; Lagatie, Ole; Arien, Kevin K.
分享
收藏An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified target靶向多功能NS2A蛋白的正黄病毒抑制剂,一种此前未被识别的靶点
Borrenberghs, Doortje; Chan, Kitti Wing Ki; Van Brandt, Sven; Jaensch, Steffen; Choy, Milly Ming Ju; Geluykens, Peggy; Bouayadi, Asmae El; Lauwers, Dax; Bist, Pradeep; Stoops, Bart; van de Ven, Jeroen; Vermeulen, Peter; Megens, Sarah; Thys, Kim; Peeters, Danielle; Kaptein, Suzanne J. F.; Neyts, Johan; Vasudevan, Subhash G.; Koul, Anil; Goethals, Olivia
分享
收藏
分享
收藏Discovery of 5-Azaindole Inhibitors of O-GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies5-氮杂吲哚类O-GlcNAcase抑制剂的发现,用于治疗阿尔茨海默病及相关tau蛋白病
Bouton, Jakob; Bretteville, Alexis; Tresadern, Gary; Shaffer, Paul; Austin, Nigel; Buijnsters, Peter; Cedervall, E. Peder; Darville, Nicolas; Fonteyn, Ineke; Leenaerts, Joseph; Lamenca, Carolina Martinez; Mertens, Liesbeth; Peeters, Daniele; Velter, Adriana I.; Roosbroeck, Yves Van; Ebneth, Andreas; Bartolome, Jose Manuel; Trabanco, Andres A.; Oehlrich, Daniel
分享
收藏An Ad26-MVA-BN-based therapeutic vaccine targeting HPV16 and HPV18 related disease is immunogenic in preclinical models and in women with persistent HPV infections基于Ad26-MVA-BN的靶向HPV16和HPV18相关疾病的 therapeutic vaccine 在非临床模型和持续HPV感染女性中具有免疫原性
Khan, Selina; Boedhoe, Satish; Baert, Miranda; Serroyen, Jan; Verbinnen, Thierry; Volkmann, Ariane; Kalla, Markus; Weidner, Katrin; Gars, Mathieu Le; Sadoff, Jerry; Sarnecki, Michal; Vellinga, Jort; Custers, Jerome; Scheper, Gert; Schuitemaker, Hanneke; Zahn, Roland
分享
收藏A deep joint-learning proteomics model for diagnosis of six conditions associated with dementia一种用于诊断六种与痴呆相关疾病的深度联合学习蛋白质组学模型
An, Lijun; Pichet Binette, Alexa; Hristovska, Ines; Vilkaite, Gabriele; Xiao, Yu; Zendehdel, Romina; Dong, Zijian; Smets, Bart; Saloner, Rowan; Tasaki, Shinya; Xu, Ying; Krish, Varsha; Imam, Farhad; Janelidze, Shorena; van Westen, Danielle; Stomrud, Erik; Whelan, Christopher D.; Palmqvist, Sebastian; Ossenkoppele, Rik; Mattsson-Carlgren, Niklas; Hansson, Oskar; Vogel, Jacob W.
分享
收藏
分享
收藏
分享
收藏Assessing the diagnostic performance of clinical, serological and molecular approaches to improve dengue case detection in the Peruvian Amazon评估临床、血清学和分子方法在改善秘鲁亚马逊地区登革热病例检测中的诊断性能
Hauner, Anne; Aroni Sierra, Jaide; Merino, Xiomara; Villa, Carlos; Torres, Fiorella; Lagatie, Ole; Talledo, Michael; Arien, Kevin K.; Falconi-Agapito, Francesca
分享
收藏The socioeconomic impact of inherited retinal dystrophies (IRDs) in Belgium: A cost-of-illness study比利时遗传性视网膜变性疾病(IRDs)的社会经济影响:一项疾病负担研究
Vandersmissen, Ine; Geers, Janice; Denee, Tom; Oinasmaa, Salla; Hoeben, Dagmar; Zhang, Xinyi; Aydin, Burcak; Cheung, Simone; Billiet, Lorenzo; Joniau, Inge; Daly, Avril; Simoens, Steven; Leroy, Bart P.
分享
收藏A Thorough QT Study to Assess the Effects of Milvexian on Cardiac Repolarization in Healthy Participants一项全面评估Milvexian对健康受试者心脏复极化影响的QT研究
Zannikos, Peter; Park, JongHanne; Dari, Anna; Takhtoukh, Samiha; Levesque, Paul; Plotnikov, Alexei N.; Mitra, Amitava; Ajavon-Hartmann, Antoinette; Merali, Samira; Perez Ruixo, Juan Jose; Goyal, Navin
分享
收藏Hemolytic Disease of Fetus and Newborn: A 24-Year Nationwide Cohort Study on Incidence, Management, and Outcomes胎儿和新生儿溶血病:一项关于发病率、管理和结局的24年全国队列研究
Fallach, Noga; Fitzgibbon, Marie; Karmous, Wisam; Barthelmes, Norma; Iqbal, Sofia; Hoshen, Moshe; Gazit, Sivan; Segal, Yaakov; Borsi, Andras; Noel, Wim; Mandel, Dror; Yinon, Yoav
分享
收藏An Expedient Synthetic Route to the Long-Acting RSV Inhibitor JNJ-6231 via Stereoselective Enzymatic Amination and Regioselective Alkylation
Cao, Trung D. C.; Neufeld, Katharina; Zarate, Cayetana; Nichols, Christopher James; Lellek, Vit; Deidda, Riccardo; Conza, Matteo; Schleiss, Pascal; Rinderhagen, Heiko; Pye, Philip; Muuronen, Mikko; Chen, Wenyong; Tona, Veronica; Jouffroy, Lucile; Viereck, Peter; Matcha, Kiran
分享
收藏Impact of Disease Duration on Clinical and Endoscopic Responses at 1 Year in Patients with Crohn's Disease Treated with Guselkumab: Pooled Analysis of the GALAXI 2 & 3 Studies克罗恩病患者接受 guselkumab 治疗后1年内疾病持续时间对临床和内镜反应的影响:GALAXI 2 & 3研究的合并分析
Ferrante, M.; Fumery, M.; Atreya, R.; Van Rampelbergh, R.; Van Duijnhoven, W.; Bravata, I; Nazar, M.; Van Denderen, J.; Mccaffrey, V; Armuzzi, A.
分享
收藏
分享
收藏Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework
Cuyckens, Filip; Li, Wenying; Auclair, Adam M.; Cassidy, Kenneth C.; Cantalloube, Cathy; Collins, Gary; James, Alexander D.; Gibson, Chris; Glaenzel, Ulrike; Huth, Felix; Kang, Ping; Moliner, Patricia; Pedersen, Mette L.; Piel, Isabel; Brunetti, Pietro; Schieferstein, Hanno; Wagner, David; Walker, Gregory S.; Wang, Shuai; Yue, Qin; Boer, Jason; Khojasteh, Cyrus
分享
收藏
分享
收藏Talquetamab in Japanese patients with relapsed/refractory multiple myeloma in the MonumenTAL-1 studyTalquetamab在日本复发/难治性多发性骨髓瘤患者中的MonumenTAL-1研究
Ito, Shigeki; Kuroda, Yoshiaki; Sunami, Kazutaka; Matsue, Kosei; Imada, Kazunori; Tamura, Hideto; Fujikawa, Ei; Yamazaki, Hiroshi; Takamoto, Mikihiro; Pei, Lixia; Qin, Xiang; Masterson, Tara J.; Campagna, Michela; Vreys, Veronique; Lau, Bonnie W.; Takamatsu, Yasushi
分享
收藏18F-Radiopharmaceutical Diversification Enabled by Deaminative Cross-Electrophile Couplings通过脱氨基交叉-亲电体偶联实现18F-放射性药物多样化
Ogilvy, Isabella F.; Ford, Joseph; Ortalli, Sebastiano; Renders, Evelien; Hayes, Thomas R.; Liu, Shuanglong; Mortiers, Inne; Nikolopoulou, Anastasia; Sorlin, Alexandre M.; Trabanco, Andres A.; Tredwell, Matthew; Buijnsters, Peter J. J. A.; Salter, Rhys; Gouverneur, Veronique
分享
收藏