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Lhasa Limited

学者数166
论文数109
被引数1
关联论文 (108)
发表时间
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In silico prediction of Ames mutagenicity for organosilicon compounds: Exploring and enhancing chemical space boundaries基于计算机的有机硅化合物Ames致突变性预测：探索和增强化学空间边界
errRegulatory Toxicology and Pharmacology
IF3.5
err2026-09-29
err0
PREAI
errSchmitt, Barbara G.; Benfenati, Emilio; Foster, Robert S.; Kocks, Grace; Raitano, Giuseppa; Tennant, Rachael E.; Forlini, Carole; Gura, Eckart; Seidel, Shawn; Koraichi-Emeriau, Farah
err分享
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Applicability of the ICH M7 Guidelines for Assessing Less-than-Lifetime Exposure to Nitrosamine Impurities in Drug ProductsICH M7指导原则在评估药物产品中亚硝胺杂质低于一生暴露情况下的适用性
errRegulatory Toxicology and Pharmacology
IF3.5
err2026-09-11
err0
PREAI
errSusan P. Felter; Joel P. Bercu; Robert A. Jolly; Timothy J. McGovern; Yi Yang; Alejandra Trejo-Martin; Roland Froetschl; Bodo Haas; Kelly Brant; Alisa Vespa; David J. Ponting; Anthony Lynch; Ashley M. Mudd; Angela White; Andreas Zeller; Raechel Puglisi
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Toxicological assessment of potential leachables in parenteral drug products: Bioavailability adjustment considerations注射剂产品中潜在浸出物的毒理学评估：生物利用度调整考虑
errRegulatory Toxicology and Pharmacology
IF3.5
err2026-08-01
err0
PREAI
errBoobier, Samuel; Chilton, Martyn; Molnar, Lance; Parris, Patricia
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Industrial Genotoxicology Group: 38th Annual Meeting Report工业遗传毒理学组：第38届年会报告
errMutagenesis
IF4.3
err2026-07-09
err0
PREAI
errGrace Kocks; Fahima Begum; Peter Ceuppens; Robert S Foster; Paul Fowler; David Kirkland; Karen Philp; David J Ponting; Siret Saaremagi; Robert Smith; Benjamin P Thornton; Claudia Ventura; Abbie Williams; Amy Wilson
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Which carcinogenicity study should I use? Automated identification of reliable studies我应该使用哪种致癌性研究？可靠研究的自动识别
errRegulatory Toxicology and Pharmacology
IF3.5
err2026-06-01
err0
PREAI
errThresher, Andrew; Halliday, Jessica E.; Kocks, Grace; Odebamowo, Samuel; Silveira, Gabriela O.; Fowkes, Adrian; Barber, Christopher G.; Ponting, David J.
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Theoretical and Experimental Assessment of Nitrosamine Risk in Industrial Solvent Recovery工业溶剂回收中硝基亚胺风险的理论及实验评估
errACS Sustainable Chemistry & Engineering
IF0
err2026-05-21
err0
errOAAI
errPeter Ritzler; Holger Bauer; Michael Burns; Brunhilde Guessregen; Andrés González de Castilla; Stephanie Peper; Naiffer Romero; Joerg Schlingemann; Jonathan Stanway; Simone Tomasi
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err收藏
Nitrosamine Ames Data Review and Method Development: proceedings of a US FDA/HESI workshop亚硝胺Ames测试数据回顾与方法开发：美国FDA/HESI研讨会论文集
errMutagenesis
IF4.3
err2026-03-01
err0
PREAI
errAtrakchi, Aisar; Puglisi, Raechel; Bercu, Joel; Cheung, Jennifer; Czich, Andreas; Froestchl, Roland; Davis-Bruno, Karen; Heflich, Robert H.; Kobets, Tetyana; McGovern, Timothy J.; Lynch, Anthony; Selby, Max; Schuler, Maik; Silveira, Gabriela De Oliveira; Vespa, Alisa; Whomsley, Rhys; Chen, Connie L.
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Establishing Best Practice for N-Nitrosamine Read-Across and Surrogate Selection建立N-亚硝胺读跨和替代物选择的最佳实践
errRegulatory Toxicology and Pharmacology
IF3.5
err2025-12-20
err0
PREAI
errDavid J. Ponting; Gabriela de Oliveira Silveira; Philip Rowell; Crina I. Heghes; Adrian Fowkes; Christopher G. Barber
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Development of a Skin Sensitization Site-of-Contact Exposure Threshold (SoCET) for Botanicals and Natural Substances开发一种用于植物和天然物质的皮肤致敏接触部位暴露阈值（SoCET）
errFood and Chemical Toxicology
IF3.5
err2025-11-09
err0
PREAI
errYuan Gao; Martyn Chilton; Cindy A. Ryan; Spiro Stilianoudakis; Lori Reinsalu; Cristin Albertson; Petra S. Kern
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err收藏
Computational mechanistic study on N-nitrosation reaction of secondary amines二级胺N-亚硝化反应的计算机机制研究
errJOURNAL OF MOLECULAR MODELING
IF2.5
err2025-10-16
err0
PREAI
errKawamura, Meire Y.; Ponting, David J.; Barber, Chris G.; Burns, Michael J.
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Evaluating the ability of defined approaches to predict the human skin sensitisation potential of chemicals previously untested in New Approach Methodologies评估定义的方法预测先前未在新型方法学中测试的化学物质的人体皮肤致敏潜能的能力
errRegulatory Toxicology and Pharmacology
IF3.5
err2025-10-13
err0
PREAI
errMartyn L. Chilton; Tasha Jones; Adrian Fowkes; Donna S. Macmillan; Darren Kidd
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Nitrite Testing in Excipients – Industry Best Practices辅料中的亚硝酸盐测试——行业最佳实践
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-08-12
err0
errOAAI
errSebastian Hickert; Kevin Näf; Jinjian Zheng; Tamas Balogh; Chris D. Smith; Juan Manuel Pallicer; Tom van Wijk; Roy Akkermans; Stéphanie Thonne; Giorgio Blom; James Sabatowski; Emma Pata; Grace Kocks; Gemma Packer
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Industrial Case Studies Demonstrating Applicability of ICH M7 Control Options 3 and 4 for Nitrosamine Control
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2025-03-01
err0
PREAI
errUrquhart, Michael W.; Burns, Michael J.; Bernardoni, Frank; Clark, Hugh F.; Crochard, Jean-Philippe; De Benedetti, Alessandro; Dirat, Olivier; Fennell, Jared W.; Gall, Malcolm A. Y.; Galli, Marzia; Hildbrand, Stefan; Kallemeyn, Jeffrey M.; Kuhl, Nadine; Mack, Daniel J.; Moessner, Christian; Pascoe, David D.; Pozzoli, Alessandro; Risch, Philippe; Roberts, Alastair J.; Teasdale, Andrew; Thiel, Oliver R.; Tomlin, Paula; Whitehead, Andrew
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Comprehensive extractables and leachables sensitization analysis and practical application of a risk-based approach to sensitization assessment for parenteral drug products全面的可提取物和可浸出物敏化分析和基于风险的方法在肠胃外药物产品敏化评估中的实际应用
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2025-03-01
err0
PREAI
errParris, Patricia; Whelanb, Geraldine; Chilton, Martyn L.; Beaumonth, Claire; Burild, Anders; Bruen, Uma; Callis, Courtney; Graham, Jessica; Kovalovai, Natalia; Martin, Elizabeth A.; Masuda-Herrera, Melisa; Worsoek, Carsten; Alamil, Anissa; Bercuj, Joel; Doronm, Dvir; Dusenbury, Kristen; Fu, Qiang; Griffin, Troy; Hillegass, Jedd; Johann, Esther; Koenig, Agnes; Macho, Nina; Martirosyan, Alina; Oded, Kobi; Guarch, Constanca Porredon; Schmitz, Matthew; Stanard, Brad; Tien, Eric; Udovic, Erika; Xu, Haiyan; Cruz, Maureen T.; Nagao, Lee
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Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakes药物产品中N-亚硝胺杂质的控制: 推进当前CPCA框架并支持稳健化合物特定可接受摄入量的推导
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2025-02-01
err0
PREAI
errPonting, David J.; Czich, Andreas; Felter, Susan P.; Glowienke, Susanne; Harvey, James S.; Nudelman, Raphael; Schlingemann, Joerg; Simon, Stephanie; Smith, Graham F.; Teasdale, Andrew; Thomas, Robert
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Sort & Slice: a simple and superior alternative to hash-based folding for extended-connectivity fingerprintsSort & Slice: 用于扩展连接指纹的基于哈希的折叠的简单而优越的替代方案
errJOURNAL OF CHEMINFORMATICS
IF5.7
err2024-12-03
err0
errOAAI
errDablander, Markus; Hanser, Thierry; Lambiotte, Renaud; Morris, Garrett M.
err分享
err收藏
Reactivities of N-Nitrosamines against Common Reagents and Reaction ConditionsN-亚硝胺对常用试剂和反应条件的反应性
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2024-09-18
err2
errOAAI
errHodgin, George A.; Burns, Michael J.; Deadman, Benjamin J.; Roberts, Christopher S.; Hii, King Kuok Mimi; Nguyen, Bao N.
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A developmental and reproductive toxicity adverse outcome pathway network to support safety assessments
errCOMPUTATIONAL TOXICOLOGY
IF2.9
err2024-09-01
err1
PREAI
errMyden, Alun; Cayley, Alex; Davies, Robert; Jones, Jade; Kane, Steven; Newman, Daniel; Payne, Martin P.; Ude, Victor C.; Vessey, Jonathan D.; White, Emma; Fowkes, Adrian
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From model performance to decision support - The rise of computational toxicology in chemical safety assessments
errCOMPUTATIONAL TOXICOLOGY
IF2.9
err2024-09-01
err2
PREAI
errBarber, C.; Fowkes, A.; Hanser, T.; Heghes, C.
err分享
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Structuring expert review using AOPs: Enabling robust weight-of-evidence assessments for carcinogenicity under ICH S1B(R1)
errCOMPUTATIONAL TOXICOLOGY
IF2.9
err2024-09-01
err0
PREAI
errStalford, Susanne A.; Cayley, Alex N.; Fowkes, Adrian; de Oliveira, Antonio Anax F.; Xanthis, Ioannis; Barber, Christopher G.
err分享
err收藏