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D

David W. Holden

imperial college london

79H指数
247论文数
2.5W被引数
收录论文 57
发表时间
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MAP4Ks drive cell death in response to Salmonella SpvB-induced actin depolymerizationMAP4Ks驱动细胞死亡以响应沙门菌SpvB诱导的肌动蛋白去聚合
errmBio
IF4.7
err2026-05-01
err0
PREAI
errPallett, Mitchell A.; Tocci, Romina; Majstorovic, Andrea; Everatt, Elena; Panagi, Ioanna; Diaz-del-Olmo, Ines; Godlee, Camilla; Thurston, Teresa L. M.; Holden, David W.
err分享
err收藏
When Every Call Counts: Insights from an Outer Regional Cohort of Palliative Care Patients Using a Navigation Service in South Australia当每一次呼叫都至关重要：来自南澳大利亚外区域姑息治疗患者使用导航服务的队列研究洞察
errPalliative Medicine Reports
IF0
err2026-01-01
err0
PREAI
errSwetenham, Kate; Tieman, Jennifer; Holden, David; Bisset, Amber; Ricci, Mariana; Bahrami, Mohammad Amin
err分享
err收藏
Mammalian and Bacterial Adaptors Function as Co-Disinhibitory Pairs to Activate the E3 ubiquitin ligase WWP2哺乳动物和细菌适配器作为共去抑制对来激活E3泛素连接酶WWP2
errJournal of Biological Chemistry
IF3.9
err2025-10-22
err0
errOAAI
errSamkeliso V. Blundell; Mei Liu; Romina Tocci; Andrea Majstorovic; Solène Tsang; David W. Holden
err分享
err收藏
Effects of cladribine on intrathecal and peripheral B and plasma cells
errCLINICAL AND EXPERIMENTAL IMMUNOLOGY
IF3.8
err2024-12-12
err0
errOAAI
errAllen-Philbey, Kimberley; Stephenson, Sophie; Doody, Gina; Macdougall, Amy; Aboulwafaali, Mohammad; Ammoscato, Francesca; Andrews, Michael; Gnanapavan, Sharmilee; Giovannoni, Gavin; Grigoriadou, Sofia; Hickey, Alaco; Holden, David W.; Lock, Helen; Papachatzaki, Maria; Redha, Iman; Baker, David; Tooze, Reuben; Schmierer, Klaus
err分享
err收藏
Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex
errMBIO
IF4.7
err2024-07-17
err1
errOAAI
errYu, Xiu-Jun; Xie, Haixia; Li, Yan; Liu, Mei; Hou, Ruhong; Predeus, Alexander V.; Sepulveda, Blanca M. Perez; Hinton, Jay C. D.; Holden, David W.; Thurston, Teresa L. M.
err分享
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A phase 2a open-label clinical trial to determine the effect of famciclovir on EBV activity as measured by EBV shedding in the saliva of patients with multiple sclerosis
errMULTIPLE SCLEROSIS JOURNAL
IF5
err2023-12-22
err0
errOAAI
errDobson, Ruth; Holden, David; Vickaryous, Nicola; Bestwick, Jonathan; George, Katila; Sayali, Tatiana; Bianchi, Lucia; Wafa, Mohammad; Gold, Julian; Giovannoni, Gavin
err分享
err收藏
Abiotic Stress Mitigation: A Case Study from 21 Trials Using a Natural Organic Matter Based Biostimulant across Multiple Geographies非生物胁迫缓解: 来自21个试验的案例研究，使用基于天然有机物的生物刺激剂在多个地理位置
errAGRONOMY-BASEL
IF3.4
err2023-02-28
err9
errOAAI
errSleighter, Rachel L.; Hanson, Terry; Holden, David; Richards, Kristen M.
err分享
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The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments
errPLOS PATHOGENS
IF4.9
err2022-05-27
err7
errOAAI
errGodlee, Camilla; Cerny, Ondrej E.; Liu, Mei; Blundell, Samkeliso W.; Gallagher, Alanna M.; Shahin, Meriam M.; Holden, David M.
err分享
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CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD
errPLOS PATHOGENS
IF4.9
err2021-07-27
err18
errOAAI
errCerny, Ondrej; Godlee, Camilla; Tocci, Romina; Cross, Nancy E.; Shi, Haoran; Williamson, James C.; Alix, Eric; Lehner, Paul J.; Holden, David W.
err分享
err收藏
Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2021-06-01
err14
errOAAI
errMatthews-Palmer, Teige R. S.; Gonzalez-Rodriguez, Nayim; Calcraft, Thomas; Lagercrantz, Signe; Zachs, Tobias; Yu, Xiu-Jun; Grabe, Grzegorz J.; Holden, David W.; Nans, Andrea; Rosenthal, Peter B.; Rouse, Sarah L.; Beeby, Morgan
err分享
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CSF neurofilament light chain testing as an aid to determine treatment strategies in MS
errNEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
IF7.5
err2020-11-01
err13
errOAAI
errReyes, Saul; Smets, Ide; Holden, David; Carrillo-Loza, Karina; Christmas, Tatiana; Bianchi, Lucia; Ammoscato, Francesca; Turner, Benjamin; Marta, Monica; Schmierer, Klaus; Giovannoni, Gavin; Gnanapavan, Sharmilee
err分享
err收藏
Salmonella SPI-2 type III secretion system-dependent inhibition of antigen presentation and T cell functionSPI-2沙门菌III型分泌系统对抗原呈递和T细胞功能的依赖性抑制
errIMMUNOLOGY LETTERS
IF2.8
err2019-11-01
err17
errOAAI
errCerny, Ondrej; Holden, David W.
err分享
err收藏
Type II Toxin-Antitoxin Systems and Persister CellsII型毒素-抗毒素系统和持久细胞
errMBIO
IF4.7
err2018-11-07
err28
errOAAI
errHolden, David W.; Errington, Jeff
err分享
err收藏
SsaV Interacts with SsaL to Control the Translocon-to-Effector Switch in the Salmonella SPI-2 Type Three Secretion System
errMBIO
IF4.7
err2018-11-07
err29
errOAAI
errYu, Xiu-Jun; Grabe, Grzegorz J.; Liu, Mei; Mota, Luis Jaime; Holden, David W.
err分享
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The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2016-12-01
err45
errOAAI
errGrabe, Grzegorz J.; Zhang, Yue; Przydacz, Michal; Rolhion, Nathalie; Yang, Yi; Pruneda, Jonathan N.; Komander, David; Holden, David W.; Hare, Stephen A.
err分享
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The new bacteriology
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2016-11-05
err0
errOAAI
errCossart, Pascale; Holden, David; Busby, Stephen
err分享
err收藏
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
errNATURE COMMUNICATIONS
IF15.7
err2016-11-03
err111
errOAAI
errThurston, Teresa L. M.; Matthews, Sophie A.; Jennings, Elliott; Alix, Eric; Shao, Feng; Shenoy, Avinash R.; Birrell, Mark A.; Holden, David W.
err分享
err收藏
Salmonella Effectors SseF and SseG Interact with Mammalian Protein ACBD3 (GCP60) To Anchor Salmonella-Containing Vacuoles at the Golgi Network
errMBIO
IF4.7
err2016-09-07
err56
errOAAI
errYu, Xiu-Jun; Liu, Mei; Holden, David W.
err分享
err收藏
Cytosolic Replication of Group A Streptococcus in Human Macrophages (vol 7, e00020-16, 2016)
errMBIO
IF4.7
err2016-07-06
err1
errOAAI
errO'Neill, Alan M.; Thurston, Teresa L. M.; Holden, David W.
err分享
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The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases
errMOLECULAR CELL
IF16.6
err2016-07-01
err126
errOAAI
errPruneda, Jonathan N.; Durkin, Charlotte H.; Geurink, Paul P.; Ovaa, Huib; Santhanam, Balaji; Holden, David W.; Komander, David
err分享
err收藏

研究方向

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合作学者
合作期刊
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Rino Rappuoli
H 指数: 143 · 论文数: 1.3K
J
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P
Pascale Cossart
H 指数: 125 · 论文数: 604
J
John Trowsdale
H 指数: 115 · 论文数: 549
S
Samuel I. Miller
H 指数: 109 · 论文数: 303
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