未登录 分享 收藏
分享 收藏
分享 收藏
A novel long-acting relaxin-2 fusion, AZD3427, improves cardiac performance in non-human primates with cardiac dysfunction 一种新型的长效松弛素-2融合蛋白AZD3427能够改善心脏功能不全的非人灵长类动物的心脏功能。 Papworth, Monika; Kulkarni, Spoorthy; Antonsson, Madeleine; Sermadiras, Isabelle; Hovdal, Daniel; Connolly, Kathleen; Olsson, Jan; Shukla, Animesh; Cotton, Peter; Althage, Magnus; Paterson, Judy; Martin, Esther; Wolny, Marcin; Ferraro, Franco; Sadowska, Agnieszka; Hao, Weidong; Larsson, Niklas; Backmark, Anna; Marlow, Tom; Perez, Rosario; Jermutus, Lutz; Omar, Sami; George, Richard T.; Gabrielsen, Anders; Pettersen, Daniel; Jennbacken, Karin 分享 收藏
First-in-human study to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of RBD4059, a GalNAc-siRNA drug targeting coagulation factor XI (FXI), in healthy subjects Gabrielsen, A.; Feng, Z.; Fu, J.; Ueckert, S.; Egnell, L.; Wikstrom, J.; Wei, W.; Chen, G.; Friend, R.; Zhan, H.; Liang, Z.; Gao, S.; Gan, L. 分享 收藏
Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study Connolly, Kathleen; George, Richard; Omar, Sami; Matsson, Elin; Astrand, Magnus; Althage, Magnus; Pettersen, Daniel; Mohamed, Esha; Fang, Kelly; Lima, Joao A. C.; Kujacic, Mirjana; Odesjo, Helena; Turton, Michelle; Johannesson, Petra; Gabrielsen, Anders; Ufnal, Marcin 分享 收藏
Degree of multilingual engagement modulates resting state oscillatory activity across the lifespan 多语言参与程度在整个生命周期中调节静息状态的振荡活动 Voits, Toms; Deluca, Vincent; Hao, Jiuzhou; Elin, Kirill; Abutalebi, Jubin; Dunabeitia, Jon Andoni; Berglund, Gaute; Gabrielsen, Anders; Rook, Janine; Thomsen, Hilde; Waagen, Philipp; Rothman, Jason 分享 收藏
Safety, Tolerability, and Pharmacodynamics of AZD3366 (Optimized Human CD39L3 Apyrase) Alone and in Combination With Ticagrelor and Acetylsalicylic Acid: A Phase 1, Randomized, Placebo-Controlled Study Kardassis, Dimitris; Egnell, Ann-Charlotte; Astrand, Magnus; Daniels, Samuel J.; Whatling, Carl; Fjellstrom, Ola; Gabrielsen, Anders 分享 收藏
Balcinrenone plus dapagliflozin in patients with heart failure and chronic kidney disease: Results from the phase 2b MIRACLE trial Balcinrenone联合dapagliflozin治疗心力衰竭和慢性肾病患者: 2b期奇迹试验的结果 Lam, Carolyn S. P.; Kober, Lars; Kuwahara, Koichiro; Lund, Lars H.; Mark, Patrick B.; Mellbin, Linda G.; Schou, Morten; Pizzato, Patricia Ely; Gabrielsen, Anders; Gasparyan, Samvel B.; Ghiretti, Alessandro; Hartleib-Geschwindner, Judith; Housler, Greggory J.; Fanti, Paolo; Leonsson-Zachrisson, Maria; McMurray, John J. V.; Solomon, Scott D. 分享 收藏
Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction CD39L3的重组人可溶性结构域和替格瑞洛: 实验性心肌梗死的心脏保护作用 Vilahur, Gemma; Radike, Monika; Sutelman, Pablo; Ben-Aicha, Soumaya; Gutierrez, Manuel; Casani, Laura; Hovdal, Daniel; Ongstad, Emily L.; Gabrielsen, Anders; Hidalgo, Alberto; Fjellstrom, Ola; Carlsson, Leif; Badimon, Lina 分享 收藏
Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results Lam, Carolyn S. P.; Lund, Lars H.; Shah, Sanjiv J.; Voors, Adriaan A.; Erlinge, David; Saraste, Antti; Pirazzi, Carlo; Grove, Erik L.; Barasa, Anders; Schou, Morten; Aziz, Ahmed; Svedlund, Sara; van Wijngaarden, Jan; Lindstedt, Eva-Lotte; Gustavsson, Andreas; Nelander, Karin; Garkaviy, Pavlo; Gan, Li-Ming; Gabrielsen, Anders 分享 收藏
Rationale and design of ENDEAVOR: A sequential phase 2b-3 randomized clinical trial to evaluate the effect of myeloperoxidase inhibition on symptoms and exercise capacity in heart failure with preserved or mildly reduced ejection fraction Lund, Lars H.; Lam, Carolyn S. P.; Pizzato, Patricia E.; Gabrielsen, Anders; Michaelsson, Erik; Nelander, Karin; Ericsson, Hans; Holden, Julie; Folkvaljon, Folke; Mattsson, Andrea; Collen, Anna; Aurell, Malin; Whatling, Carl; Baldus, Stephan; Drelich, Grzegorz; Goudev, Assen; Merkely, Bela; Bergh, Niklas; Shah, Sanjiv J. 分享 收藏
Safety and efficacy of the 5-lipoxygenase-activating protein inhibitor AZD5718 in patients with recent myocardial infarction: The phase 2a FLAVOUR study Prescott, Eva; Angeras, Oskar; Erlinge, David; Grove, Erik L.; Hedman, Marja; Jensen, Lisette O.; Pernow, John; Saraste, Antti; Akerblom, Axel; Svedlund, Sara; Rudvik, Anna; Knochel, Jane; Lindstedt, Eva-Lotte; Garkaviy, Pavlo; Gan, Li-Ming; Gabrielsen, Anders 分享 收藏
Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial Squire, Iain B.; Gabrielsen, Anders; Greasley, Peter J.; Wernevik, Linda; Hartleib-Geschwindner, Judith; Holden, Julie; Johansson, Susanne; Rudvik, Anna; Sanchez, Jose; Bamberg, Krister; Melin, Johanna; Whittaker, Andrew 分享 收藏
Arginase 1 is upregulated at admission in patients with ST-elevation myocardial infarction Tengbom, John; Cederstrom, Sofia; Verouhis, Dinos; Bohm, Felix; Eriksson, Per; Folkersen, Lasse; Gabrielsen, Anders; Jernberg, Tomas; Lundman, Pia; Persson, Jonas; Saleh, Nawzad; Settergren, Magnus; Sorensson, Peder; Tratsiakovich, Yahor; Tornvall, Per; Jung, Christian; Pernow, John 分享 收藏
Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques Endothelin-1通过ETB受体增加精氨酸酶2的表达和活性，并在人动脉粥样硬化斑块中与精氨酸酶2共表达 Rafnsson, Arnar; Matic, Ljubica Perisic; Lengquist, Mariette; Mahdi, Ali; Shemyakin, Alexey; Paulsson-Berne, Gabrielle; Hansson, Goran K.; Gabrielsen, Anders; Hedin, Ulf; Yang, Jiangning; Pernow, John 分享 收藏
New candidate genes for ST-elevation myocardial infarction Cederstrom, S.; Lundman, P.; Folkersen, L.; Paulsson-Berne, G.; Karadimou, G.; Eriksson, P.; Caidahl, K.; Gabrielsen, A.; Jernberg, T.; Persson, J.; Tornvall, P. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
