David R. Greaves - Publications, H-index & Citations

David R. Greaves

south parks road

75H指数

288论文数

2.1W被引数

收录论文 93

发表时间

Steric control of signaling bias in the immunometabolic receptor GPR84 GPR84免疫代谢受体信号偏倚的立体控制

Nature Communications

IF15.7

2026-09-05

OAAI

Pinqi Wang; Xuan Zhang; Abdul-Akim Guseinov; Laura Jenkins; Carl von Hallerstein; Jonathan D. Colburn; Rowan Ives; Vincent B. Luscombe; Sara Marsango; Listiana Oktavia; Arun Raja; David R. Greaves; Philip C. Biggin; Graeme Milligan; Cheng Zhang; Irina G. Tikhonova; Angela J. Russell

Cardiac lymphatics retain LYVE-1-dependent macrophages during neonatal mouse heart regeneration 心脏淋巴管在新生小鼠心脏再生期间保留LYVE-1依赖性巨噬细胞

cardiovascular research

IF10.8

2025-09-17

OAAI

Benjamin G. Chapman; Konstantinos Klaourakis; Carla de Villiers; Mala Gunadasa-Rohling; Maria-Alexa Cosma; Susanna T. E. Cooper; Kshitij Mohan; Michael Weinberger; Carolyn A. Carr; David R. Greaves; David G. Jackson; Daniela Pezzolla; Robin P. Choudhury; Joaquim M. Vieira; Paul R. Riley

Exposure to elevated cholesterol results in a non-reversible epigenetic and metabolic shift in macrophages associated with increased residual inflammatory risk

EUROPEAN HEART JOURNAL

IF35.6

2024-10-28

PREAI

Purvis, G.; Tom, T.; Jiang, J.; Greaves, D. R.; O'callaghan, C.; Channon, K. M.

Ly6Chi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

CELLS

IF5.2

2024-05-26

OAAI

Purvis, Gareth S. D.; Mcneill, Eileen; Wright, Benjamin; Channon, Keith M.; Greaves, David R.

Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2024-04-01

OAAI

Chaffey, Laura E.; Roberti, Annabell; Bowman, Amelia; O'Brien, Conan J. O.; Som, Liliana; Purvis, Gareth S. D.; Greaves, David R.

Integrating isolation using label-independent microfluidics and advanced staining for comprehensive Circulating Tumor Cell Analysis

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-03-01

PREAI

Ciccioli, M.; Greaves, D.; Young, A.; Cottingham, A.; Bourne, R.; Pailhes-Jimenez, A. S.

Deficiency of factor- inhibiting HIF creates a tumor- promoting immune microenvironment 抑制因子HIF的缺乏会产生促进肿瘤的免疫微环境

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-02-29

OAAI

Ma, Jingyi; Al Moussawi, Khatoun; Lou, Hantao; Chan, Hok Fung; Wang, Yihua; Chadwick, Joseph; Phetsouphanh, Chansavath; Slee, Elizabeth A.; Zhong, Shan; Leissing, Thomas M.; Roth, Andrew; Qin, Xiao; Chen, Shuo; Yin, Jie; Ratnayaka, Indrika; Hu, Yang; Louphrasitthiphol, Pakavarin; Taylor, Lewis; Bettencourt, Paulo J. G.; Muers, Mary; Greaves, David R.; Mcshane, Helen; Goldin, Robert; Soilleux, Elizabeth J.; Coleman, Mathew L.; Ratcliffe, Peter J.; Lu, Xin

Biased agonists of GPR84 and insights into biological control GPR84的偏向性激动剂和对生物防治的见解

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-01-23

OAAI

Luscombe, Vincent B.; Wang, Pinqi; Russell, Angela J.; Greaves, David R.

Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-12-26

OAAI

Wang, Pinqi; Raja, Arun; Luscombe, Vincent B.; Bataille, Carole J. R.; Lucy, Daniel; Rogga, Vanessa V.; Greaves, David R.; Russell, Angela J.

Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-10-01

OAAI

Luscombe, Vincent B.; Baena-Lopez, Luis Alberto; Bataille, Carole J. R.; Russell, Angela J.; Greaves, David R.

MafB is essential for renal development and F4/80 expression in macrophages

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

193

OAAI

Moriguchi, Takashi; Hamada, Michito; Morito, Naoki; Terunuma, Tsumoru; Hasegawa, Kazuteru; Zhang, Chuan; Yokomizo, Tomomasa; Esaki, Ritsuko; Kuroda, Etsushi; Yoh, Keigyou; Kudo, Takashi; Nagata, Michio; Greaves, David R.; Engel, James Douglas; Yamamoto, Masayuki; Takahashi, Satoru

CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

CELL REPORTS

IF6.9

2023-03-01

OAAI

Devi, Savita; Indramohan, Mohanalaxmi; Jager, Elisabeth; Carriere, Jessica; Chu, Lan H.; de Almeida, Lucia; Greaves, David R.; Stehlik, Christian; Dorfleutner, Andrea

Assaying Macrophage Chemotaxis Using Fluid-Walled Microfluidics

ADVANCED MATERIALS TECHNOLOGIES

IF6.2

2022-07-19

OAAI

Deroy, Cyril; Rumianek, Agata N.; Wheeler, James H. R.; Nebuloni, Federico; Cook, Peter R.; Greaves, David R.; Walsh, Edmond J.

A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-06

OAAI

Rumianek, Agata N.; Davies, Ben; Channon, Keith M.; Greaves, David R.; Purvis, Gareth S. D.

Bruton's TK regulates myeloid cell recruitment during acute inflammation

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2022-03-15

OAAI

Purvis, Gareth S. D.; Aranda-Tavio, Haidee; Channon, Keith M.; Greaves, David R.

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

DEVELOPMENT

IF3.6

2021-02-03

OAAI

Cahill, Thomas J.; Sun, Xin; Ravaud, Christophe; Villa del Campo, Cristina; Klaourakis, Konstantinos; Lupu, Irina-Elena; Lord, Allegra M.; Browne, Cathy; Jacobsen, Sten Eirik W.; Greaves, David R.; Jackson, David G.; Cowley, Sally A.; James, William; Choudhury, Robin P.; Miguel Vieira, Joaquim; Riley, Paul R.

How Have Leukocyte In Vitro Chemotaxis Assays Shaped Our Ideas about Macrophage Migration?

BIOLOGY-BASEL

IF3.5

2020-12-02

OAAI

Rumianek, Agata N.; Greaves, David R.

X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure 没有功能性布鲁顿酪氨酸激酶的X连锁免疫缺陷小鼠免受败血症诱导的多器官功能衰竭

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-10-07

OAAI

O'Riordan, Caroline E.; Purvis, Gareth S. D.; Collotta, Debora; Krieg, Nadine; Wissuwa, Bianka; Sheikh, Madeeha H.; Ferreira Alves, Gustavo; Mohammad, Shireen; Callender, Lauren A.; Coldewey, Sina M.; Collino, Massimo; Greaves, David R.; Thiemermann, Christoph

Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-08-26

OAAI

Purvis, Gareth S. D.; Collino, Massimo; Aranda-Tavio, Haidee; Chiazza, Fausto; O'Riordan, Caroline E.; Zeboudj, Lynda; Mohammad, Shireen; Collotta, Debora; Verta, Roberta; Guisot, Nicolas E. S.; Bunyard, Peter; Yaqoob, Magdi M.; Greaves, David R.; Thiemermann, Christoph

Single Cell Transcriptomics Reveals How Hyperlipidaemia Alters Monocyte/macrophage Differentiation At Sites Of Inflammation

FASEB JOURNAL

IF4.2

2020-04-16

OAAI

Purvis, Gareth; McNeill, Eileen; Wright, Benjamin; Lockstone, Helen; Channon, Keith; Greaves, David

研究方向