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R

Ronald M. Evans

Salk Institute for Biological Studies
H指数:211
被引数:18.9万

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Gemcitabine and nab-paclitaxel with or without the VDR agonist paricalcitol for metastatic pancreatic cancer: a randomized, multiarm, run-in phase trial

吉西他滨和nab-紫杉醇联合或不联合VDR激动剂帕立骨化醇治疗转移性胰腺癌: 一项随机，多臂，磨合期试验

Nature Cancer
IF28.5
2026-05-250
PRE
Kimberly J. Perez; Andressa Dias Costa; Alexander Jordan; Thomas B. Karasic; Dalia Elganainy; Suryun Kim; Chen Yuan; Dan Y. Gui; Runzi Tan; Sung Chul Hong; Xi Wang; Simona Cristea; Emma Coleman; Morgan Truitt; Tae Gyu Oh; Hui Zheng; C. Sloane Furniss; Lauren Brais; Alexandra Bird; Josh Remland; Vasilena Gocheva; Jennifer S. Thalappillil; Mark Anderson; James M. Cleary; Andrea Enzinger; Marios Giannakis; Kimmie Ng; Douglas A. Rubinson; Benjamin Schlechter; Rishi Surana; Harshabad Singh; Thomas Abrams; Ursina Teitelbaum; Natallia Izgur; Eliezer Allen; Peter S. Winter; Srivatsan Raghavan; Jen Jen Yeh; Daniel Von Hoff; Christopher Liddle; Michael Downes; Ronald M. Evans; Peter O’Dwyer; Andrew Aguirre; Jonathan A. Nowak; Brian M. Wolpin
Targeting Wnt/β-catenin and circadian regulator restores PRC2/EZH2-controlled chromatin bivalency and suppresses cell state diversity

靶向Wnt/β-catenin和昼夜节律调节因子恢复PRC2/EZH2调控的染色质双相性并抑制细胞状态多样性

Journal of Clinical Investigation
IF13.6
2026-05-010
PRE
Yang, Yatian; Zhang, Xiong; Venkadakrishnan, Varadha Balaji; Zou, Hongye; Zheng, Xingling; Guo, Shiyao; Chen, Christopher Z.; Borowsky, Alexander D.; Corey, Eva; Evans, Ronald M.; Gao, Allen C.; Dall'Era, Marc A.; Zoubeidi, Amina; Lara, Primo N.; Kung, Hsing-Jien; Chen, Xinbin; Beltran, Himisha; Chen, Hong-Wu
Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice

多层级转录调控糖原代谢，协调雄性小鼠白色脂肪细胞的产热重塑。

Nature Communications
IF15.7
2025-12-160
OAAI
Haipeng Fu; Seoyeon Lee; Nathan R. Zemke; Weiwei Fan; Yunqing Wang; James Garza; David Tin; Bryce Villao; Bichen Zhang; Xianda Ma; Jinyang Zhang; Tangran Dong; Yuyao Ren; Michael Downes; Ronald M. Evans; Bing Ren; Alan R. Saltiel
Neutrophils preserve energy storage in sympathetically activated adipocytes

中性粒细胞维持交感神经激活的脂肪细胞中的能量储存

Nature
IF48.5
2025-12-100
PRE
Seunghwan Son; Cindy Xu; Haipeng Fu; Churaibhon Wisessaowapak; Joseph M. Valentine; Garam An; Janice Jang; Maddox Dinh; Yang Dai; Weiwei Fan; Ruth T. Yu; Michael Downes; Wei Ying; Yuliya Skorobogatko; Ronald M. Evans; Alan R. Saltiel
Adipocyte Heparan Sulfate Determines Type 2 Diabetes Susceptibility in Mice via FGF1-Mediated Glucose Regulation.

脂肪细胞硫酸乙酰肝素通过FGF1介导的葡萄糖调节确定小鼠2型糖尿病易感性。

Molecular Metabolism
IF6.6
2025-10-080
OAAI
Chung-Jui Yu; Ariane R. Pessentheiner; Sihao Liu; Sarah Wax; Marissa L. Maciej-Hulme; Chelsea D. Painter; Bastian Ramms; Daniel R. Sandoval; Anthony Quach; Natalie DeForest; G.Michelle Ducasa; Chiara Tognaccini; Caroline Labib; Norah Al-Azzam; Friederike Haumann; Greg Trieger; Patrick Secrest; Amit Majithia; Aaron C. Petrey; Kamil Godula; Annette R. Atkins; Michael Downes; Ronald M. Evans; Philip L.S.M. Gordts
Antibody–bottlebrush prodrug conjugates for targeted cancer therapy
Nature Biotechnology
IF41.7
2025-09-090
PRE
Bin Liu; Hung V.-T. Nguyen; Yivan Jiang; Aiden X. Wang; Valerie Lensch; Zehao Sun; Zane H. Boyer; Philip A. Raftopoulos; Yutong Dai; Piper L. MacNicol; Yuyan Wang; Nidhi Jyotsana; Wencong Wang; Sachin Bhagchandani; Sanjana Hemdev; Peyton Shieh; Samantha L. Kristufek; Magalie Boucher; Michael Downes; Ronald M. Evans; David W. C. MacMillan; Jeremiah A. Johnson
Estrogen- related receptors regulate innate and adaptive muscle mitochondrial energetics through cooperative and distinct actions

雌激素相关受体通过协同和独特的作用调节先天性和适应性肌肉线粒体能量代谢。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-05-120
OA
Fan, Weiwei; Oh, Tae Gyu; Wang, Hui J.; Crossley, Lillian; He, Mingxiao; Robbins, Hunter; Koopari, Chandra; Dai, Yang; Truitt, Morgan L.; Liddle, Christopher; Yu, Ruth T.; Atkins, Annette R.; Downes, Michael; Evans, Ronald M.
CAnceR IN PreGnancy (CARING) - a retrospective study of cancer diagnosed during pregnancy in the United Kingdom
BRITISH JOURNAL OF CANCER
IF6.8
2024-02-211
OA
Baxter, M. A.; Denholm, M.; Kingdon, S. J.; Kathirgamakarthigeyan, S.; Parikh, S.; Shakir, R.; Johnson, R.; Martin, H.; Walton, M.; Yao, W.; Swan, A.; Samuelson, C.; Ren, X.; Cooper, A.; Gray, H-L; Clifton, S.; Ball, J.; Gullick, G.; Anderson, M.; Dodd, L.; Hayhurst, H.; Salama, M.; Shotton, R.; Britton, F.; Christodoulou, T.; Abdul-Hamid, A.; Eichholz, A.; Evans, R. M.; Wallroth, P.; Gibson, F.; Poole, K.; Rowe, M.; Harris, J.
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
NATURE METABOLISM
IF20.8
2024-01-2919
OAAI
Xia, Wenmin; Veeragandham, Preethi; Cao, Yu; Xu, Yayun; Rhyne, Torrey E.; Qian, Jiaxin; Hung, Chao-Wei; Zhao, Peng; Jones, Ying; Gao, Hui; Liddle, Christopher; Yu, Ruth T.; Downes, Michael; Evans, Ronald M.; Ryden, Mikael; Wabitsch, Martin; Wang, Zichen; Hakozaki, Hiroyuki; Schoneberg, Johannes; Reilly, Shannon M.; Huang, Jianfeng; Saltiel, Alan R.
Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function
CIRCULATION
IF38.6
2024-01-167
PRE
Xu, Weiyi; Billon, Cyrielle; Li, Hui; Wilderman, Andrea; Qi, Lei; Graves, Andrea; Rideb, Jernie Rae Dela Cruz; Zhao, Yuanbiao; Hayes, Matthew; Yu, Keyang; Losby, McKenna; Hampton, Carissa S.; Adeyemi, Christiana M.; Hong, Seok Jae; Nasiotis, Eleni; Fu, Chen; Oh, Tae Gyu; Fan, Weiwei; Downes, Michael; Welch, Ryan D.; Evans, Ronald M.; Milosavljevic, Aleksandar; Walker, John K.; Jensen, Brian C.; Pei, Liming; Burris, Thomas; Zhang, Lilei
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation

TLR4/TRAF6-dependent信号通路介导NCoR共激活因子复合物形成促进炎症基因激活

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-01-023
OAAI
Abe, Yohei; Kofman, Eric R.; Ouyang, Zhengyu; Cruz-Becerra, Grisel; Spann, Nathanael J.; Seidman, Jason S.; Troutman, Ty D.; Stender, Joshua D.; Taylor, Havilah; Fan, Weiwei; Link, Verena M.; Shen, Zeyang; Sakai, Juro; Downes, Michael; Evans, Ronald M.; Kadonaga, James T.; Rosenfeld, Michael G.; Glass, Christopher K.

研究方向

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M
Michael Downes
H 指数:83论文数:318被引数:3.8万
R
Ruth T. Yu
H 指数:70论文数:155被引数:2.5万
A
Annette R. Atkins
H 指数:45论文数:108被引数:1.2万
C
Christopher Liddle
H 指数:72论文数:251被引数:2.1万
W
Weiwei Fan
H 指数:38论文数:102被引数:6,206
T
Tae Gyu Oh
H 指数:23论文数:84被引数:2,324
G
Grant D. Barish
H 指数:39论文数:61被引数:9,310
J
Jerrold M. Olefsky
H 指数:147论文数:672被引数:9.2万
N
Nasun Hah
H 指数:26论文数:47被引数:6,459
C
Chih‐Hao Lee
H 指数:48论文数:375被引数:1.2万