未登录Design and Synthesis of Pyrazolomorphinan Derivatives as Novel Delta Opioid Receptor Agonists
Fujii, Hideaki; Iwamatsu, Chiharu; Ishizaki, Saki; Nakamura, Hideki; Yamada, Daisuke; Yamada, Shuma; Niwa, Junichi; Yoshioka, Toshinori; Liu, Pengfei; Shirakura, Shintaro; Karaki, Fumika; Hirayama, Shigeto; Saitoh, Akiyoshi .png)
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收藏SEX DIFFERENCES IN THE REDUCTION OF HOPELESSNESS IN M OPIOID RECEPTOR DEFICIENT MICE BY ADDITIVE EFFECTS OF Δ OPIOID RECEPTOR AGONISTS绝望感的减少在M阿片受体缺陷小鼠中通过δ阿片受体激动剂的附加效应所表现的性别差异Moriya, Yuki; Kasahara, Yoshiyuki; Shimada, Masafumi; Sakakibara, Yasufumi; Fujii, Hideaki; Nagase, Hiroshi; Ide, Soichiro; Ikeda, Kazutaka; Hall, Frank Scott; Uhl, George R.; Sora, Ichiro 分享 收藏 分享 收藏 SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted NeurogenesisIwai, Takashi; Mishima, Rei; Hirayama, Shigeto; Nakajima, Honoka; Oyama, Misa; Watanabe, Shun; Fujii, Hideaki; Tanabe, Mitsuo 分享 收藏 Anti-Schistosomal activity and ADMET properties of 1,2,5-oxadiazinane-containing compound synthesized by visible-light photoredox catalysisItoh, Kennosuke; Nakahara, Hiroki; Takashino, Atsushi; Hara, Aya; Katsuno, Akiho; Abe, Yuriko; Mizuguchi, Takaaki; Karaki, Fumika; Hirayama, Shigeto; Nagai, Kenichiro; Seki, Reiko; Sato, Noriko; Okuyama, Kazuki; Hashimoto, Masashi; Tokunaga, Ken; Ishida, Hitoshi; Mikami, Fusako; Kwofie, Kofi Dadzie; Kawada, Hayato; Lin, Bangzhong; Nunomura, Kazuto; Kanai, Toshio; Hatta, Takeshi; Tsuji, Naotoshi; Haruta, Junichi; Fujii, Hideaki 分享 收藏 Discovery of 7-Azanorbornane-Based Dual Agonists for the Delta and Kappa Opioid Receptors through an In Situ Screening ProtocolKaraki, Fumika; Takamori, Taro; Kawakami, Koumei; Sakurai, Sae; Hidaka, Kyoko; Ishii, Kei; Oki, Tomoya; Sato, Noriko; Atsumi, Nao; Ashizawa, Karin; Taguchi, Ai; Ura, Asuka; Naruse, Toko; Hirayama, Shigeto; Nonaka, Miki; Miyano, Kanako; Uezono, Yasuhito; Fujii, Hideaki 分享 收藏 Role for μ-opioid receptor in antidepressant effects of 8-opioid receptor agonist KNT-127Moriya, Yuki; Kasahara, Yoshiyuki; Shimada, Masafumi; Sakakibara, Yasufumi; Fujii, Hideaki; Nagase, Hiroshi; Ide, Soichiro; Ikeda, Kazutaka; Hall, F. Scott; Uhl, George R.; Sora, Ichiro 分享 收藏 Visible-light-Induced synthesis of imidazolidines through formal [3+2] cycloaddition of aromatic imines with N,N,N', N'-tetramethyldiaminomethaneItoh, Kennosuke; Ishii, Nanase; Takashino, Atsushi; Hara, Aya; Kon, Satoshi; Mizuguchi, Takaaki; Karaki, Fumika; Hirayama, Shigeto; Shibagaki, Yoshio; Nagai, Kenichiro; Sato, Noriko; Tokunaga, Ken; Suzuki, Mitsuaki; Hashimoto, Masashi; Fujii, Hideaki 分享 收藏 Evaluation of the Intracellular Signaling Activities of κ-Opioid Receptor Agonists, Nalfurafine Analogs; Focusing on the Selectivity of G-Protein- and β-Arrestin-Mediated PathwaysYamaguchi, Masahiro; Miyano, Kanako; Hirayama, Shigeto; Karasawa, Yusuke; Ohshima, Kaori; Uezono, Eiko; Komatsu, Akane; Nonaka, Miki; Fujii, Hideaki; Yamaguchi, Keisuke; Iseki, Masako; Hayashida, Masakazu; Uezono, Yasuhito 分享 收藏 Prognostic value of machine learning for acute heart failureShimizu, M.; Miyazaki, H.; Cho, S.; Misu, Y.; Tateishi, R.; Yamaguchi, M.; Yamakami, Y.; Shimada, H.; Manno, T.; Isshiki, A.; Kimura, S.; Fujii, H.; Suzuki, M.; Nishizaki, M.; Sasano, T. 分享 收藏 分享 收藏 In Vitro Analyses of Spinach-Derived Opioid Peptides, Rubiscolins: Receptor Selectivity and Intracellular Activities through G Protein- and β-Arrestin-Mediated PathwaysKarasawa, Yusuke; Miyano, Kanako; Fujii, Hideaki; Mizuguchi, Takaaki; Kuroda, Yui; Nonaka, Miki; Komatsu, Akane; Ohshima, Kaori; Yamaguchi, Masahiro; Yamaguchi, Keisuke; Iseki, Masako; Uezono, Yasuhito; Hayashida, Masakazu 分享 收藏 Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not δ-Opioid Receptors in the G Protein Signaling PathwayMiyano, Kanako; Yoshida, Yuki; Hirayama, Shigeto; Takahashi, Hideki; Ono, Haruka; Meguro, Yoshiyuki; Manabe, Sei; Komatsu, Akane; Nonaka, Miki; Mizuguchi, Takaaki; Fujii, Hideaki; Higami, Yoshikazu; Narita, Minoru; Uezono, Yasuhito 分享 收藏 分享 收藏 Visible-Light-Induced Synthesis of 1,2,3,4-Tetrahydroquinolines through Formal [4+2] Cycloaddition of Acyclic α,β-Unsaturated Amides and Imides with N,N-DialkylanilinesItoh, Kennosuke; Nagao, Shun-ichi; Tokunaga, Ken; Hirayama, Shigeto; Karaki, Fumika; Mizuguchi, Takaaki; Nagai, Kenichiro; Sato, Noriko; Suzuki, Mitsuaki; Hashimoto, Masashi; Fujii, Hideaki 分享 收藏 The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis (vol 10, 625, 2020)Miyano, Kanako; Eto, Moeko; Hitomi, Suzuro; Matsumoto, Takashi; Hasegawa, Seiya; Hirano, Ayane; Nagabuchi, Kaori; Asai, Noriho; Uzu, Miaki; Nonaka, Miki; Omiya, Yuji; Kaneko, Atsushi; Ono, Kentaro; Fujii, Hideaki; Higami, Yoshikazu; Kono, Toru; Uezono, Yasuhito 分享 收藏 分享 收藏 Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 ReceptorsMiyano, Kanako; Ohshima, Kaori; Suzuki, Nozomi; Furuya, Saho; Yoshida, Yuki; Nonaka, Miki; Higami, Yoshikazu; Yoshizawa, Kazumi; Fujii, Hideaki; Uezono, Yasuhito 分享 收藏 The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis日本草药hangeshashto可增强口腔角质形成细胞的迁移，以促进化疗引起的口腔溃疡性粘膜炎的愈合Miyano, Kanako; Eto, Moeko; Hitomi, Suzuro; Matsumoto, Takashi; Hasegawa, Seiya; Hirano, Ayane; Nagabuchi, Kaori; Asai, Noriho; Uzu, Miaki; Nonaka, Miki; Omiya, Yuji; Kaneko, Atsushi; Ono, Kentaro; Fujii, Hideaki; Higami, Yoshikazu; Kono, Toru; Uezono, Yasuhito 分享 收藏 A New Lead Identification Strategy: Screening an sp3-rich and Lead-like Compound Library Composed of 7-Azanorbornane DerivativesKaraki, Fumika; Umemoto, Sho; Ashizawa, Karin; Oki, Tomoya; Sato, Noriko; Ogino, Takumi; Ishibashi, Naoto; Someya, Ryoto; Miyano, Kanako; Hirayama, Shigeto; Uezono, Yasuhito; Fujii, Hideaki 分享 收藏 
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