Nicole A. de Weerd - Publications, H-index & Citations

Nicole A. de Weerd

Hudson Institute of Medical Research

20H指数

74论文数

2.8K被引数

收录论文 23

发表时间

Type I interferon signaling controls the early hematopoietic expansion in response to R-glucan I型干扰素信号通路调控机体对R-葡聚糖的早期造血扩增

ISCIENCE

IF4.1

2025-05-01

OAAI

Xu, Yangsong; Lee, Man K. S.; Weerd, Nicole A. de; Fu, Ziyue; Veiga, Camilla Bertuzzo; Dragoljevic, Dragana; Sviridov, Dmitri; Hertzog, Paul J.; Fleetwood, Andrew J.; Murphy, Andrew J.

A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity 显性人类IFNAR1缺乏症的常见形式会损害ifn-α 和-ω，但不会损害ifn-β 依赖性免疫

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-12-16

OAAI

Al Qureshah, Fahd; Le Pen, Jeremie; de Weerd, Nicole A.; Moncada-Velez, Marcela; Materna, Marie; Lin, Daniel C.; Milisavljevic, Baptiste; Vianna, Fernanda; Bizien, Lucy; Lorenzo, Lazaro; Lecuit, Marc; Pommier, Jean-David; Keles, Sevgi; Ozcelik, Tayfun; Pedraza-Sanchez, Sigifredo; de Prost, Nicolas; El Zein, Loubna; Hammoud, Hassan; Ng, Lisa F. P.; Halwani, Rabih; Saheb Sharif-Askari, Narjes; Lau, Yu Lung; Tam, Anthony R.; Singh, Neha; Bhattad, Sagar; Berkun, Yackov; Chantratita, Wasun; Aguilar-Lopez, Raul; Shahrooei, Mohammad; Abel, Laurent; Bastard, Paul; Jouanguy, Emmanuelle; Beziat, Vivien; Zhang, Peng; Rice, Charles M.; Cobat, Aurelie; Zhang, Shen-Ying; Hertzog, Paul J.; Casanova, Jean-Laurent; Zhang, Qian

A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer

NATURE IMMUNOLOGY

IF27.6

2024-11-21

PREAI

Guanizo, Aleks C.; Luong, Quinton; Jayasekara, W. Samantha N.; de Geus, Eveline D.; Inampudi, Chaitanya; Xue, Vincent Senyang; Chen, Jasmine; de Weerd, Nicole A.; Matthews, Antony Y.; Gantier, Michael P.; Balic, Jesse J.; Arulananda, Surein; Garama, Daniel J.; Hertzog, Paul J.; Ganju, Vinod; Watkins, D. Neil; Cain, Jason E.; Gough, Daniel J.

Structure-function of type I and III interferons

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2024-02-01

PREAI

de Weerd, Nicole A.; Kurowska, Aleksandra K.; Mendoza, Juan L.; Schreiber, Gideon

Interferon-epsilon is a novel regulator of NK cell responses in the uterus

EMBO MOLECULAR MEDICINE

IF8.3

2024-01-23

OAAI

Mayall, Jemma R.; Horvat, Jay C.; Mangan, Niamh E.; Chevalier, Anne; McCarthy, Huw; Hampsey, Daniel; Donovan, Chantal; Brown, Alexandra C.; Matthews, Antony Y.; de Weerd, Nicole A.; de Geus, Eveline D.; Starkey, Malcolm R.; Kim, Richard Y.; Daly, Katie; Goggins, Bridie J.; Keely, Simon; Maltby, Steven; Baldwin, Rennay; Foster, Paul S.; Boyle, Michael J.; Tanwar, Pradeep S.; Huntington, Nicholas D.; Hertzog, Paul J.; Hansbro, Philip M.

Epithelially Restricted Interferon Epsilon Protects Against Colitis

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2024-01-01

OAAI

de Geus, Eveline D.; Volaric, Jennifer S.; Matthews, Antony Y.; Mangan, Niamh E.; Chang, Janet; Ooi, Joshua D.; de Weerd, Nicole A.; Giles, Edward M.; Hertzog, Paul J.

Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization

CELL REPORTS

IF6.9

2022-04-01

OAAI

Lee, Kevin Ming-Chin; Achuthan, Adrian A.; De Souza, David P.; Lupancu, Tanya J.; Binger, Katrina J.; Lee, Man K. S.; Xu, Yangsong; McConville, Malcolm J.; de Weerd, Nicole A.; Dragoljevic, Dragana; Hertzog, Paul J.; Murphy, Andrew J.; Hamilton, John A.; Fleetwood, Andrew J.

Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML 浆细胞样DCs的表观遗传激活驱动AML的IFNAR依赖性治疗分化

CANCER DISCOVERY

IF33.3

2022-03-21

OAAI

Salmon, Jessica M.; Todorovski, Izabela; Stanley, Kym L.; Bruedigam, Claudia; Kearney, Conor J.; Martelotto, Luciano G.; Rossello, Fernando; Semple, Timothy; Arnau, Gisela Mir; Zethoven, Magnus; Bots, Michael; Bjelosevic, Stefan; Cluse, Leonie A.; Fraser, Peter J.; Litalien, Veronique; Vidacs, Eva; McArthur, Kate; Matthews, Antony Y.; Gressier, Elise; de Weerd, Nicole A.; Lichte, Jens; Kelly, Madison J.; Hogg, Simon J.; Hertzog, Paul J.; Kats, Lev M.; Vervoort, Stephin J.; De Carvalho, Daniel D.; Scheu, Stefanie; Bedoui, Sammy; Kile, Benjamin T.; Lane, Steven W.; Perkins, Andrew C.; Wei, Andrew H.; Dominguez, Pilar M.; Johnstone, Ricky W.

Structural integrity with functional plasticity: what type I IFN receptor polymorphisms reveal

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2020-08-26

OAAI

de Weerd, Nicole A.; Vivian, Julian P.; Lim, San S.; Huan, Stephanie U-Shane; Hertzog, Paul J.

A structural star in interferon gamma signaling

IMMUNOLOGY AND CELL BIOLOGY

IF3

2019-05-26

OAAI

Hertzog, Paul J.; de Weerd, Nicole A.

Auto-phosphorylation Represses Protein Kinase R Activity

SCIENTIFIC REPORTS

IF3.9

2017-03-10

OAAI

Wang, Die; de Weerd, Nicole A.; Willard, Belinda; Polekhina, Galina; Williams, Bryan R. G.; Sadler, Anthony J.

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling 干扰素 α/β 受体亚基1 (IFNAR1) 的热点支持其与干扰素-β 的相互作用并决定信号传导

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-03-01

OAAI

de Weerd, Nicole A.; Matthews, Antony Y.; Pattie, Phillip R.; Bourke, Nollaig M.; Lim, San S.; Vivian, Julian P.; Rossjohn, Jamie; Hertzog, Paul J.

Interferon epsilon promotes HIV restriction at multiple steps of viral replication

IMMUNOLOGY AND CELL BIOLOGY

IF3

2017-01-03

PREAI

Garcia-Minambres, Albert; Eid, Sahar G.; Mangan, Niamh E.; Pade, Corinna; Lim, San S.; Matthews, Antony Y.; de Weerd, Nicole A.; Hertzog, Paul J.; Mak, Johnson

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

NATURE IMMUNOLOGY

IF27.6

2013-07-21

241

PREAI

de Weerd, Nicole A.; Vivian, Julian P.; Nguyen, Thao K.; Mangan, Niamh E.; Gould, Jodee A.; Braniff, Susie-Jane; Zaker-Tabrizi, Leyla; Fung, Ka Yee; Forster, Samuel C.; Beddoe, Travis; Reid, Hugh H.; Rossjohn, Jamie; Hertzog, Paul J.

Fine structural and functional characterization of a unique IFNβ/Ifnar1 signaling axis

CYTOKINE

IF3.7

2012-09-01

PREAI

De Weerd, N.; Nguyen, T.; Vivian, J.; Mangan, N. E.; Gould, J. A.; Noppert, S.; Zaker-Tabrizi, L.; Beddoe, T.; Reid, H. H.; Rossjohn, J.; Hertzog, P. J.

The interferons and their receptors-distribution and regulation

IMMUNOLOGY AND CELL BIOLOGY

IF3

2012-03-13

436

OAAI

de Weerd, Nicole A.; Thao Nguyen

SOCS1 selectively regulates type I IFN signaling

CYTOKINE

IF3.7

2011-10-01

PREAI

Piganis, Rebecca; de Weerd, Nicole; Gould, Jodee; Scott, Bernadette; Forster, Sam; Nicholson, Sandra; Hertzog, Paul

Characterization of a novel type I Interferon, IFNε

CYTOKINE

IF3.7

2011-10-01

PREAI

Stifter, Sebastian A.; Fung, Kayee; Mangan, Niamh; de Weerd, Nicole; Hertzog, Paul

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-09-01

164

OAAI

Piganis, Rebecca A. R.; De Weerd, Nicole A.; Gould, Jodee A.; Schindler, Christian W.; Mansell, Ashley; Nicholson, Sandra E.; Hertzog, Paul J.

Structure-function characterization of type I interferon receptor signaling regulation

CYTOKINE

IF3.7

2008-09-01

PREAI

de Weerd, Nicole A.; Piganis, Rebecca; Zaker-Tabrizi, Leyla; Reid, Hugh; Fenner, Jennifer; Noppert, Susie; Gould, Jodee; Scott, Bernadette; Rossjohn, Jamie; Zhao, W.; Lee, C.; Plumlee, C.; Schindler, Christian; Hertzog, Paul J.

研究方向