Michael O. Hottiger - Publications, H-index & Citations

Michael O. Hottiger

department of molecular mechanisms of disease

72H指数

236论文数

2.0W被引数

收录论文 137

发表时间

From Bench to Clinic: The 2024 FASEB Scientific Research Conference on NAD Metabolism and Signaling 从实验室到临床：2024年FASEB科学研討会关于NAD代谢与信号传导

Molecular Medicine

IF6.4

2025-10-31

OAAI

Shin-ichiro Imai; Eija Pirinen; Michael N. Sack; Jonas T. Treebak; Charalampos Tzoulis; Santina Bruzzone; Andreas H. Guse; Michael O. Hottiger; Xiaolu A. Cambronne

Unleashing viral mimicry: A combinatorial strategy to enhance the efficacy of PARP7 inhibitors 释放病毒模仿: 增强PARP7抑制剂疗效的组合策略

BIOESSAYS

IF2.7

2024-11-06

OAAI

Manetsch, Patrick; Hottiger, Michael O.

Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation

BIOMEDICINES

IF3.9

2024-07-20

OAAI

Bohi, Flurina; Hottiger, Michael O.

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency

EMBO REPORTS

IF6.2

2024-02-08

OAAI

Rupasinghe, Meneka; Bersaglieri, Cristiana; Pedrioli, Deena M. Leslie; Pedrioli, Patrick G. A.; Panatta, Martina; Hottiger, Michael O.; Cinelli, Paolo; Santoro, Raffaella

Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex

CELL REPORTS

IF6.9

2024-02-01

OAAI

Zhang, Qinxin; Xian, Wei; Li, Zilin; Lu, Qian; Chen, Xindi; Ge, Jinli; Tang, Zhiheng; Liu, Bohao; Chen, Zhe; Gao, Xiang; Hottiger, Michael; Zhang, Peipei; Qiu, Jiazhang; Shao, Feng; Liu, Xiaoyun

Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation

NATURE COMMUNICATIONS

IF15.7

2024-01-02

OAAI

Schwarz, Simon D.; Xu, Jianming; Gunasekera, Kapila; Schurmann, David; Vagbo, Cathrine B.; Ferrari, Elena; Slupphaug, Geir; Hottiger, Michael O.; Schaer, Primo; Steinacher, Roland

PARP7-mediated ADP- ribosylation of FRA1 promotes cancer cell growth by repressing IRF1-and IRF3-dependent apoptosis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-11-27

OAAI

Manetsch, Patrick; Boehi, Flurina; Nowak, Kathrin; Pedrioli, Deena M. Leslie; Hottiger, Michael O.

Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma PARP和MAPK抑制剂的联合治疗克服了晚期黑色素瘤中表型转换驱动的耐药性

CANCER RESEARCH

IF16.6

2023-09-20

PREAI

Ferretti, Lorenza P.; Bohi, Flurina; Pedrioli, Deena M. Leslie; Cheng, Phil F.; Ferrari, Elena; Baumgaertner, Petra; Alvarado-Diaz, Abdiel; Sella, Federica; Cereghetti, Alessandra; Turko, Patrick; Wright, Roni H.; De Bock, Katrien; Speiser, Daniel E.; Ferrari, Roberto; Levesque, Mitchell P.; Hottiger, Michael O.

Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-17

OAAI

Gueldenpfennig, Anka; Hopp, Ann-Katrin; Muskalla, Lukas; Manetsch, Patrick; Raith, Fabio; Hellweg, Lars; Doerdelmann, Cyril; Pedrioli, Deena M. Leslie; Johnsson, Kai; Superti-Furga, Giulio; Hottiger, Michael O.

Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development

CELLS

IF5.2

2023-08-16

OAAI

Kamaletdinova, Tatiana; Zong, Wen; Urbanek, Pavel; Wang, Sijia; Sannai, Mara; Grigaravicius, Paulius; Sun, Wenli; Fanaei-Kahrani, Zahra; Mangerich, Aswin; Hottiger, Michael O.; Li, Tangliang; Wang, Zhao-Qi

Altered cytoplasmic and nuclear ADP-ribosylation levels analyzed with an improved ADP-ribose binder are a prognostic factor in renal cell carcinoma

JOURNAL OF PATHOLOGY CLINICAL RESEARCH

IF3.7

2023-03-31

OAAI

Schraml, Peter; Aimi, Fabio; Zoche, Martin; Aguilera-Garcia, Domingo; Arnold, Fabian; Moch, Holger; Hottiger, Michael O.

SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

294

OAAI

Rajamohan, Senthilkumar B.; Pillai, Vinodkumar B.; Gupta, Madhu; Sundaresan, Nagalingam R.; Birukov, Konstantin G.; Samant, Sadhana; Hottiger, Michael O.; Gupta, Mahesh P.

ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Minotti, Roberta; Andersson, Anneli; Hottiger, Michael O.

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death Tankyrase介导的ADP-核糖基化是TNF诱导的死亡的调节剂

SCIENCE ADVANCES

IF12.5

2022-05-13

OAAI

Liu, Lin; Sandow, Jarrod J.; Pedrioli, Deena M. Leslie; Samson, Andre L.; Silke, Natasha; Kratina, Tobias; Ambrose, Rebecca L.; Doerflinger, Marcel; Hu, Zhaoqing; Morrish, Emma; Chau, Diep; Kueh, Andrew J.; Fitzibbon, Cheree; Pellegrini, Marc; Pearson, Jaclyn S.; Hottiger, Michael O.; Webb, Andrew, I; Lalaoui, Najoua; Silke, John

Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses

CELL DISCOVERY

IF12.5

2021-11-02

OAAI

Boehi, Flurina; Manetsch, Patrick; Hottiger, Michael O.

ADP-ribosyltransferases, an update on function and nomenclature ADP-核糖基转移酶，功能和命名的更新

FEBS JOURNAL

IF4.2

2021-09-13

188

OAAI

Luscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan; Bai, Peter; Chang, Paul; Cohen, Michael; Corda, Daniela; Dantzer, Francoise; Daugherty, Matthew D.; Dawson, Ted M.; Dawson, Valina L.; Deindl, Sebastian; Fehr, Anthony R.; Feijs, Karla L. H.; Filippov, Dmitri V.; Gagne, Jean-Philippe; Grimaldi, Giovanna; Guettler, Sebastian; Hoch, Nicolas C.; Hottiger, Michael O.; Korn, Patricia; Kraus, W. Lee; Ladurner, Andreas; Lehtio, Lari; Leung, Anthony K. L.; Lord, Christopher J.; Mangerich, Aswin; Matic, Ivan; Matthews, Jason; Moldovan, George-Lucian; Moss, Joel; Natoli, Gioacchino; Nielsen, Michael L.; Niepel, Mario; Nolte, Friedrich; Pascal, John; Paschal, Bryce M.; Pawlowski, Krzysztof; Poirier, Guy G.; Smith, Susan; Timinszky, Gyula; Wang, Zhao-Qi; Yelamos, Jose; Yu, Xiaochun; Zaja, Roko; Ziegler, Mathias

Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-08-24

OAAI

Leutert, Mario; Duan, Yinghui; Winzer, Riekje; Menzel, Stephan; Tolosa, Eva; Magnus, Tim; Hottiger, Michael O.; Koch-Nolte, Friedrich; Rissiek, Bjoern

Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers

MODERN PATHOLOGY

IF5.5

2021-08-01

OAAI

Aimi, Fabio; Moch, Holger; Schraml, Peter; Hottiger, Michael O.

Establishment of a Mass-Spectrometry-Based Method for the Identification of the In Vivo Whole Blood and Plasma ADP-Ribosylomes

JOURNAL OF PROTEOME RESEARCH

IF3.6

2021-05-25

OAAI

Luthi, Stephanie C.; Howald, Anna; Nowak, Kathrin; Graage, Robert; Bartolomei, Giody; Neupert, Christine; Sidler, Xaver; Pedrioli, Deena Leslie; Hottiger, Michael O.

Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight

CELLS

IF5.2

2021-03-19

OAAI

Hopp, Ann-Katrin; Hottiger, Michael O.

研究方向