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A

Alexis Courbet

Howard Hughes Medical Institute
H指数:16
被引数:4,735

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荣誉奖项

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Membrane protein solubilization and structure determination using de novo–designed proteins

使用从头设计的蛋白质进行膜蛋白增溶和结构测定

Science
IF45.8
2026-07-020
PRE
Ljubica Mihaljević; David E. Kim; Pooja D. Bandawane; Helen E. Eisenach; Andrew J. Borst; Alexis Courbet; Connor Weidle; Kenneth D. Carr; Everton Bettin; Qiushi Liu; Aldo T. Trejos; Sagardip Majumder; Surabhi Kokane; Alexander Stevens; Edin Muratspahić; Thomas Schlichthaerle; Marc Expòsit; Xinting Li; Mila Lamb; Analisa Nicole Azcárraga Murray; Rashmi Ravichandran; Elizabeth C. Williams; Shuyuan Hu; Lynda Stuart; Linda Grillová; Nicholas R. Thomson; Michael Landreh; Pengxiang Chang; Lorenzo Giacani; Melissa J. Caimano; Kelly L. Hawley; Neil P. King; David Baker
The past, present and future of de novo protein design

从头蛋白质设计的过去、现在与未来

Nature
IF48.5
2026-04-290
PRE
Wei Yang; Shunzhi Wang; Gyu Rie Lee; Jason Z. Zhang; Alexis Courbet; David Juergens; Xinru Wang; Thomas Schlichthaerle; Mohamad Abedi; Robert Ragotte; Linna An; Indrek Kalvet; Sam Pellock; Ljubica Mihaljevic; Cameron Glasscock; Arvind Pillai; Adam Broerman; Nathan Ennist; Ella Haefner; Nora McNamara-Bordewick; Ian Haydon; Lance Stewart; Gaurav Bhardwaj; David Baker
Accurate computational design of three-dimensional protein crystals
NATURE MATERIALS
IF38.5
2023-10-1621
OA
Li, Zhe; Wang, Shunzhi; Nattermann, Una; Bera, Asim K.; Borst, Andrew J.; Yaman, Muammer Y.; Bick, Matthew J.; Yang, Erin C.; Sheffler, William; Lee, Byeongdu; Seifert, Soenke; Hura, Greg L.; Nguyen, Hannah; Kang, Alex; Dalal, Radhika; Lubner, Joshua M.; Hsia, Yang; Haddox, Hugh; Courbet, Alexis; Dowling, Quinton; Miranda, Marcos; Favor, Andrew; Etemadi, Ali; Edman, Natasha I.; Yang, Wei; Weidle, Connor; Sankaran, Banumathi; Negahdari, Babak; Ross, Michael B.; Ginger, David S.; Baker, David
De novo design of protein structure and function with RFdiffusion

具有RFdiffusion的蛋白质结构和功能的从头设计

Nature
IF48.5
2023-07-110
OAAI
Joseph L. Watson; David Juergens; Nathaniel R. Bennett; Brian L. Trippe; Jason Yim; Helen E. Eisenach; Woody Ahern; Andrew J. Borst; Robert J. Ragotte; Lukas F. Milles; Basile I. M. Wicky; Nikita Hanikel; Samuel J. Pellock; Alexis Courbet; William Sheffler; Jue Wang; Preetham Venkatesh; Isaac Sappington; Susana Vázquez Torres; Anna Lauko; Valentin De Bortoli; Emile Mathieu; Sergey Ovchinnikov; Regina Barzilay; Tommi S. Jaakkola; Frank DiMaio; Minkyung Baek; David Baker
Top-down design of protein architectures with reinforcement learning

基于强化学习的蛋白质结构自顶向下设计

Science
IF45.8
2023-01-010
OAAI
Isaac D. Lutz; Shunzhi Wang; Christoffer Norn; Alexis Courbet; Andrew J. Borst; Yan Ting Zhao; Annie M. Dosey; Longxing Cao; Jinwei Xu; Elizabeth M. Leaf; Catherine Treichel; Patrisia Litvicov; Zhe Li; Alex Goodson; Paula Rivera-Sánchez; Ana-Maria Bratovianu; Minkyung Baek; Neil P. King; Hannele Ruohola‐Baker; David A. Baker
Hallucinating symmetric protein assemblies

幻觉对称蛋白组装

Science
IF45.8
2022-01-010
OAAI
Basile I. M. Wicky; Lukas F. Milles; Alexis Courbet; Robert J. Ragotte; Justas Dauparas; Elias S. Kinfu; Samuel W. K. Tipps; Ryan D. Kibler; Minkyung Baek; Frank DiMaio; Xinting Li; Lauren P. Carter; Alex Kang; Hannah Nguyen; Asim K. Bera; D. Baker
Robust deep learning–based protein sequence design using ProteinMPNN

使用ProteinMPNN进行基于深度学习的鲁棒蛋白质序列设计

Science
IF45.8
2022-01-010
OAAI
Justas Dauparas; Ivan V. Anishchenko; Nathaniel R. Bennett; Hua Bai; Robert J. Ragotte; Lukas F. Milles; Basile I. M. Wicky; Alexis Courbet; Robbert J. de Haas; Neville P. Bethel; Philip J. Y. Leung; Timothy F. Huddy; Samuel J. Pellock; Doug Tischer; F. Chan; Brian Koepnick; Hannah Nguyen; Alex Kang; Banumathi Sankaran; Asim K. Bera; Neil P. King; David A. Baker
Generation of ordered protein assemblies using rigid three-body fusion

使用刚性三体融合生成有序蛋白质组装体

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-05-3126
OA
Vulovic, Ivan; Yao, Qing; Park, Young-Jun; Courbet, Alexis; Norris, Andrew; Busch, Florian; Sahasrabuddhe, Aniruddha; Merten, Hannes; Sahtoe, Danny D.; Ueda, George; Fallas, Jorge A.; Weaver, Sara J.; Hsia, Yang; Langan, Robert A.; Plueckthun, Andreas; Wysocki, Vicki H.; Veesler, David; Jensen, Grant J.; Baker, David

研究方向

暂未获取到该数据
D
David Baker
H 指数:0论文数:65被引数:68
A
Andrew J. Borst
H 指数:24论文数:79被引数:3,534
A
Asim K. Bera
H 指数:38论文数:264被引数:7,784
F
Franck Molina
H 指数:36论文数:150被引数:5,637
B
Basile I. M. Wicky
H 指数:20论文数:52被引数:5,844
R
Robert J. Ragotte
H 指数:19论文数:44被引数:5,214
A
Alex Kang
H 指数:33论文数:123被引数:6,046
É
Éric Renard
H 指数:66论文数:553被引数:2.2万
L
Lukas F. Milles
H 指数:24论文数:72被引数:6,031
C
Connor Weidle
H 指数:16论文数:55被引数:1,184