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The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament 人类脊柱后纵韧带骨化患者中ENPP1缺乏的患病率以及ENPP1酶疗法在鼠类脊柱后纵韧带骨化模型中的前期疗效 Srivastava, Shivani; Kato, Hajime; Von Kroge, Simon; Weise, Keith; Stabach, Paul; Lopez, Sam G.; O'brien, Kevin; Lester, Ethan R.; Kim, Hana; Ishaq, Tayyaba; Dammen-Brower, Kris; Schinke, Thorsten; Kimura, Soichiro; Miyahara, Junya; Doi, Toru; Oshima, Yasushi; Yarema, Kevin J.; Carpenter, Thomas O.; Sabbagh, Yves; Tommasini, Steven M.; Ito, Nobuaki; Oheim, Ralf; Braddock, Demetrios T. 分享 收藏
Dual Pathway Inhibition Triggers Glioblastoma Metabolic Collapse 双通路抑制触发胶质母细胞瘤代谢崩溃 Michaelides, Loizos; Gil, Beatriz Fernandez; de Llano, Juan Pablo Navarro-Garcia; Weil, Raegan; Morales-Gallel, Raquel; Dammen-Brower, Kris; Aafreen, Safiya; Ulloa-Navas, Maria Jose; Garcia-Verdugo, Jose Manuel; Yarema, Kevin; Quinones-Hinojosa, Alfredo 分享 收藏
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Production of site-specific antibody conjugates using metabolic glycoengineering and novel Fc glycovariants Bernstein, Zachary J.; Gierke, Taylor R.; Dammen-Brower, Kris; Tzeng, Stephany Y.; Zhu, Stanley; Chen, Sabrina S.; Wilson, D. Scott; Green, Jordan J.; Yarema, Kevin J.; Spangle, Jamine B. 分享 收藏
A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models Stabach, Paul R.; Sims, Dominique; Gomez-Banuelos, Eduardo; Zehentmeier, Sandra; Dammen-Brower, Kris; Bernhisel, Andrew; Kujawski, Sophia; Lopez, Sam G.; Petri, Michelle; Goldman, Daniel W.; Lester, Ethan R.; Le, Quan; Ishaq, Tayyaba; Kim, Hana; Srivastava, Shivani; Kumar, Deepika; Pereira, Joao P.; Yarema, Kevin J.; Koumpouras, Fotios; Andrade, Felipe; Braddock, Demetrios T. 分享 收藏
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Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway Saeui, Christopher T.; Shah, Sagar R.; Fernandez-Gil, Beatriz I. .; Zhang, Cissy; Agatemor, Christian; Dammen-Brower, Kris; Mathew, Mohit P.; Buettner, Matthew; Gowda, Prateek; Khare, Pratik; Otamendi-Lopez, Andrea; Yang, Shuang; Zhang, Hui; Le, Anne; Quinones-Hinojosa, Alfredo; Yarema, Kevin J. 分享 收藏
A versatile design platform for glycoengineering therapeutic antibodies Ludwig, Seth D.; Bernstein, Zachary J.; Agatemor, Christian; Dammen-Brower, Kris; Ruffolo, Jeffrey; Rosas, Jonah M.; Post, Jeremy D.; Cole, Robert N.; Yarema, Kevin J.; Spangler, Jamie B. 分享 收藏
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Comparison of Three Glycoproteomic Methods for the Analysis of the Secretome of CHO Cells Treated with 1,3,4-O-Bu3ManNAc Mertz, Joseph L.; Sun, Shisheng; Yin, Bojiao; Hu, Yingwei; Bhattacharya, Rahul; Bettenbaugh, Michael J.; Yarema, Kevin J.; Zhang, Hui 分享 收藏
Improving the Pharmacodynamics and In Vivo Activity of ENPP1-Fc Through Protein and Glycosylation Engineering Stabach, Paul R.; Zimmerman, Kristin; Adame, Aaron; Kavanagh, Dillon; Saeui, Christopher T.; Agatemor, Christian; Gray, Shawn; Cao, Wenxiang; de la Cruz, Enrique M.; Yarema, Kevin J.; Braddock, Demetrios T. 分享 收藏
Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression Saeui, Christopher T.; Cho, Kyung-cho; Dharmarha, Vrinda; Nairn, Alison; Galizzi, Melina; Shah, Sagar R.; Gowda, Prateek; Park, Marian; Austin, Melissa; Clarke, Amelia; Cai, Edward; Buettner, Matthew J.; Ariss, Ryan; Moremen, Kelley W.; Zhang, Hui; Yarema, Kevin J. 分享 收藏
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Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production Wang, Qiong; Chung, Cheng-Yu; Yang, Weiming; Yang, Ganglong; Chough, Sandra; Chen, Yiqun; Yin, Bojiao; Bhattacharya, Rahul; Hu, Yingwei; Saeui, Christopher T.; Yarema, Kevin J.; Betenbaugh, Michael J.; Zhang, Hui 分享 收藏
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