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J

Jennifer R. Keeffe

California Institute of Technology
H指数:24
被引数:2,935

个人简介

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教育背景

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工作经历

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荣誉奖项

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Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design

通过两步机制诱导广谱中和HIV抗体为疫苗设计提供信息

Science
IF45.8
2026-05-070
PRE
Ashwin N. Skelly; Harry B. Gristick; Hui Li; Edem Gavor; Andrew J. Connell; Edward F. Kreider; Lorie Marchitto; Michael P. Hogarty; Maddy L. Newby; Joel D. Allen; Weimin Liu; Anthony P. West; Kasirajan Ayyanathan; Mary S. Campion; Kaitlyn Winters; Colette G. Gordon; Rebecca A. Osbaldeston; Macy J. Akeley; Emily Lewis; Yingying Li; Ajay Singh; Kendra Cruickshank; Younghoon Park; Chengyan Zhao; Xuduo Li; Khaled Amereh; Elizabeth Van Itallie; John W. Carey; Amie Albertus; Andrew T. DeLaitsch; Jennifer R. Keeffe; Melinda G. Lituchy; Agnes A. Walsh; Daniel J. Morris; Rumi Habib; Frederic Bibollet-Ruche; Nitesh Mishra; Gabriel Avillion; Nicholas S. Koranda; Samantha J. Plante; Christian L. Martella; Jinery Lora; Eric J. D. Wang; Mark G. Lewis; Malcolm A. Martin; Michel C. Nussenzweig; Michael S. Seaman; Darrell J. Irvine; Kevin J. Wiehe; Barton F. Haynes; Kshitij Wagh; Bette Korber; Raiees Andrabi; Max Crispin; Drew Weissman; Pamela J. Bjorkman; Beatrice H. Hahn; George M. Shaw
Single administration of mosaic-8b RBD-nanoparticle vaccine prepared using atomic layer deposition elicits broad anti-sarbecovirus responses

单次给予通过原子层沉积制备的mosaic-8b RBD-纳米颗粒疫苗可诱导广谱抗sarbecovirus反应

iScience
IF4.1
2025-09-250
OAAI
Alexander A. Cohen; Jennifer R. Keeffe; Annie V. Rorick; Semi Rho; Ange-Celia Priso Fils; Lusineh Manasyan; Han Gao; Priyanthi N.P. Gnanapragasam; Hans H. Funke; Theodore W. Randolph; Robert L. Garcea; Pamela J. Bjorkman
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses

墨西哥和巴西的人类抗体中和蜱传黄病毒

CELL REPORTS
IF6.9
2024-06-010
OA
Rincon, Tomas Cervantes; Kapoor, Tania; Keeffe, Jennifer R.; Simonelli, Luca; Hoffmann, Hans -Heinrich; Agudelo, Marianna; Jurado, Andrea; Peace, Avery; Lee, Yu E.; Gazumyan, Anna; Guidetti, Francesca; Cantergiani, Jasmine; Cena, Benedetta; Bianchini, Filippo; Tamagnini, Elia; Moro, Simone G.; Svoboda, Pavel; Costa, Federico; Reis, Mitermayer G.; Ko, Albert I.; Fallon, Brian A.; Avila-Rios, Santiago; Reyes-Teran, Gustavo; Rice, Charles M.; Nussenzweig, Michel C.; Bjorkman, Pamela J.; Ruzek, Daniel; Varani, Luca; Macdonald, Margaret R.; Robbiani, Davide F.
Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses
NATURE NANOTECHNOLOGY
IF34.9
2024-05-065
OAAI
Hills, Rory A.; Tan, Tiong Kit; Cohen, Alexander A.; Keeffe, Jennifer R.; Keeble, Anthony H.; Gnanapragasam, Priyanthi N. P.; Storm, Kaya N.; Rorick, Annie V.; West Jr, Anthony P.; Hill, Michelle L.; Liu, Sai; Gilbert-Jaramillo, Javier; Afzal, Madeeha; Napier, Amy; Admans, Gabrielle; James, William S.; Bjorkman, Pamela J.; Townsend, Alain R.; Howarth, Mark R.
CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals
SCIENCE IMMUNOLOGY
IF16.3
2023-02-035
OAAI
Gristick, Harry B.; Hartweger, Harald; Loewe, Maximilian; van Schooten, Jelle; Ramos, Victor; Oliveira, Thiago Y.; Nishimura, Yoshiaki; Koranda, Nicholas S.; Wall, Abigail; Yao, Kai -Hui; Poston, Daniel; Gazumyan, Anna; Wiatr, Marie; Horning, Marcel; Keeffe, Jennifer R.; Hoffmann, Magnus A. G.; Yang, Zhi; Abernathy, Morgan E.; Dam, Kim-Marie A.; Gao, Han; Gnanapragasam, Priyanthi N. P.; Kakutani, Leesa M.; Pavlovitch-Bedzyk, Ana Jimena; Seaman, Michael S.; Howarth, Mark; Mcguire, Andrew T.; Stamatatos, Leonidas; Martin, Malcolm A.; West Jr, Anthony P.; Nussenzweig, Michel C.; Bjorkman, Pamela J.
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
NATURE COMMUNICATIONS
IF15.7
2023-01-1922
OAAI
Huang, Kuan-Ying A.; Chen, Xiaorui; Mohapatra, Arpita; Nguyen, Hong Thuy Vy; Schimanski, Lisa; Tan, Tiong Kit; Rijal, Pramila; Vester, Susan K. K.; Hills, Rory A. A.; Howarth, Mark; Keeffe, Jennifer R. R.; Cohen, Alexander A. A.; Kakutani, Leesa M. M.; Wu, Yi-Min; Shahed-Al-Mahmud, Md; Chou, Yu-Chi; Bjorkman, Pamela J. J.; Townsend, Alain R. R.; Ma, Che
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

在动物模型中，镶嵌RBD纳米颗粒可防止各种sarbecovirus的挑战

Science
IF45.8
2022-01-010
OA
Alexander A. Cohen; Neeltje van Doremalen; Allison J. Greaney; Hanné Andersen; Ankur Sharma; Tyler N. Starr; Jennifer R. Keeffe; Chengcheng Fan; Jonathan E. Schulz; Priyanthi N.P. Gnanapragasam; Leesa M. Kakutani; Anthony P. West; Greg A. Saturday; Yu Erica Lee; Han Gao; Claudia A. Jette; Mark G. Lewis; Tiong Kit Tan; Alain Townsend; Jesse D. Bloom; Vincent Jacobus Munster; Pamela J. Björkman
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-11-2432
OA
Escolano, Amelia; Gristick, Harry B.; Gautam, Rajeev; DeLaitsch, Andrew T.; Abernathy, Morgan E.; Yang, Zhi; Wang, Haoqing; Hoffmann, Magnus A. G.; Nishimura, Yoshiaki; Wang, Zijun; Koranda, Nicholas; Kakutani, Leesa M.; Gao, Han; Gnanapragasam, Priyanthi N. P.; Raina, Henna; Gazumyan, Ana; Cipolla, Melissa; Oliveira, Thiago Y.; Ramos, Victor; Irvine, Darrell J.; Silva, Murillo; West, Anthony P., Jr.; Keeffe, Jennifer R.; Barnes, Christopher O.; Seaman, Michael S.; Nussenzweig, Michel C.; Martin, Malcolm A.; Bjorkman, Pamela J.
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York
NATURE COMMUNICATIONS
IF15.7
2021-08-0942
OAAI
West, Anthony P., Jr.; Wertheim, Joel O.; Wang, Jade C.; Vasylyeva, Tetyana, I; Havens, Jennifer L.; Chowdhury, Moinuddin A.; Gonzalez, Edimarlyn; Fang, Courtney E.; Di Lonardo, Steve S.; Hughes, Scott; Rakeman, Jennifer L.; Lee, Henry H.; Barnes, Christopher O.; Gnanapragasam, Priyanthi N. P.; Yang, Zhi; Gaebler, Christian; Caskey, Marina; Nussenzweig, Michel C.; Keeffe, Jennifer R.; Bjorkman, Pamela J.
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2021-04-0832
OAAI
Agudelo, Marianna; Palus, Martin; Keeffe, Jennifer R.; Bianchini, Filippo; Svoboda, Pavel; Salat, Jiri; Peace, Avery; Gazumyan, Anna; Cipolla, Melissa; Kapoor, Tania; Guidetti, Francesca; Yao, Kai-Hui; Elsterova, Jana; Teislerova, Dana; Chrdle, Ales; Honig, Vaclav; Oliveira, Thiago; West, Anthony P., Jr.; Lee, Yu E.; Rice, Charles M.; MacDonald, Margaret R.; Bjorkman, Pamela J.; Ruzek, Daniel; Robbiani, Davide F.; Nussenzweig, Michel C.

研究方向

暂未获取到该数据
P
Pamela J. Björkman
H 指数:107论文数:526被引数:5.4万
M
Michel C. Nussenzweig
H 指数:183论文数:628被引数:11.8万
P
Priyanthi N.P. Gnanapragasam
H 指数:26论文数:82被引数:3,940
Y
Yu E. Lee
H 指数:15论文数:31被引数:3,690
A
Alexander A. Cohen
H 指数:16论文数:45被引数:1,938
A
Anthony P. West
H 指数:68论文数:202被引数:3.1万
D
Davide F. Robbiani
H 指数:53论文数:109被引数:2.0万
H
Harry B. Gristick
H 指数:21论文数:64被引数:4,880
C
Charles M. Rice
H 指数:166论文数:723被引数:10.1万
M
Mark Howarth
H 指数:45论文数:166被引数:1.2万