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M

Michel C. Nussenzweig

Howard Hughes Medical Institute
H指数:183
被引数:11.7万

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Broadly neutralizing antibodies in adult males living with HIV undergoing analytical treatment interruption: secondary and exploratory outcomes of the phase II randomized controlled RIO trial

在HIV感染者男性接受分析性治疗中断期间的中和抗体：RIO试验II期随机对照试验的次要和探索性结局

Nature Medicine
IF50
2026-09-150
OAAI
Marcilio J. Fumagalli; Anna Kaczynska; Marius Allombert; Ágata Lopes-Ribeiro; Mariângela de Oliveira Silva; Brianna J. Hernandez; Christy Lavine; Sebastian M. Espinosa; Helen Brown; Hanna Box; Emanuela Falaschetti; Louise-Rae Cherrill; Tamara Elliott; Ming Lee; Julie Fox; Sarah Pett; Amanda Clarke; Alison Uriel; Ole Sogaard; Rebecca Sutherland; Marta Boffito; Sabine Kinloch-Loes; Chloe Orkin; Simon Collins; Panagiota Zacharopoulou; Nicola Robison; Cintia Bittar; Thiago Oliveira; Anna Gazumyan; Mila Jankovic; Michael S. Seaman; John Frater; Marina Caskey; Sarah Fidler; Michel C. Nussenzweig
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design

通过两步机制诱导广谱中和HIV抗体为疫苗设计提供信息

Science
IF45.8
2026-05-070
PRE
Ashwin N. Skelly; Harry B. Gristick; Hui Li; Edem Gavor; Andrew J. Connell; Edward F. Kreider; Lorie Marchitto; Michael P. Hogarty; Maddy L. Newby; Joel D. Allen; Weimin Liu; Anthony P. West; Kasirajan Ayyanathan; Mary S. Campion; Kaitlyn Winters; Colette G. Gordon; Rebecca A. Osbaldeston; Macy J. Akeley; Emily Lewis; Yingying Li; Ajay Singh; Kendra Cruickshank; Younghoon Park; Chengyan Zhao; Xuduo Li; Khaled Amereh; Elizabeth Van Itallie; John W. Carey; Amie Albertus; Andrew T. DeLaitsch; Jennifer R. Keeffe; Melinda G. Lituchy; Agnes A. Walsh; Daniel J. Morris; Rumi Habib; Frederic Bibollet-Ruche; Nitesh Mishra; Gabriel Avillion; Nicholas S. Koranda; Samantha J. Plante; Christian L. Martella; Jinery Lora; Eric J. D. Wang; Mark G. Lewis; Malcolm A. Martin; Michel C. Nussenzweig; Michael S. Seaman; Darrell J. Irvine; Kevin J. Wiehe; Barton F. Haynes; Kshitij Wagh; Bette Korber; Raiees Andrabi; Max Crispin; Drew Weissman; Pamela J. Bjorkman; Beatrice H. Hahn; George M. Shaw
B lymphocyte protein factories produced by hematopoietic stem cell gene editing

造血干细胞基因编辑产生的B淋巴细胞蛋白质工厂

Science
IF45.8
2026-04-160
PRE
Harald Hartweger; Chiara Ruprecht; Kai-Hui Yao; Philippe Laffont; Gabriella Lima Dos Reis; Pengcheng Zhou; Thomas Hägglöf; Laurine Binet; Maximilian Loewe; Jun P. Hong; Tianli Xiao; Esen Sefik; Brianna Hernandez; Anna Gazumyan; Mila Jankovic; Michael S. Seaman; Giulia Costa; Sean A. Nelson; Jordan Clark; Sachie Kanatani; Patrick C. Wilson; Florian Krammer; Elena A. Levashina; Jean-Philippe Julien; Hedda Wardemann; Photini Sinnis; Leonidas Stamatatos; Richard A. Flavell; Michel C. Nussenzweig
Autologous neutralizing antibodies and polyfunctional T cells contribute to long-term HIV-1 post-intervention control

自体中和抗体和多功能T细胞有助于长期HIV-1干预后控制

Nature Immunology
IF27.6
2026-03-030
OA
Katie Fisher; Mauro A. Garcia; Giacomo S. Frattari; Chloé Naasz; Junlin Zhuo; Miriam Rosás-Umbert; Lisa L. Dietz; Anna Karina Juhl; Emma Falling Iversen; Rikke Olesen; Mariane H. Schleimann; Marie H. Pahus; Isik S. Johansen; Merle Henderson; Leah Carrere; Isabelle Roseto; Ce Gao; Xu G. Yu; Emily J. Fray; Beril Aydin; Donald Lubbeck; Jun Lai; Francesco R. Simonetti; Ali Danesh; Itzayana Miller; Pilar Mendoza; Julia Niessl; Christian Gaebler; Michael S. Seaman; Daniel E. Kaufmann; Clara Lehmann; Henning Gruell; Florian Klein; Marina Caskey; Michel C. Nussenzweig; Martin Tolstrup; R. Brad Jones; Jesper D. Gunst; Janet D. Siliciano; Mathias Lichterfeld; Robert F. Siliciano; Ole S. Søgaard
CD8+ T cell stemness precedes post-intervention control of HIV viremia

CD8+ T细胞干性先于干预后对HIV病毒血症的控制

Nature
IF48.5
2025-12-010
PRE
Zahra Kiani; Jonathan M. Urbach; Hannah Wisner; Mpho J. Olatotse; Daniel Y. Chang; Joshua A. Acklin; Alicja Piechocka-Trocha; Nathalie Bonheur; Ashok Khatri; Mathias Lichterfeld; Jesper D. Gunst; Ole S. Søgaard; Marina Caskey; Michel C. Nussenzweig; Bruce D. Walker; David R. Collins
Correlates of HIV-1 control after combination immunotherapy

HIV-1控制与联合免疫治疗的相关因素

Nature
IF48.5
2025-12-010
PRE
M. J. Peluso; D. A. Sandel; A. N. Deitchman; S. J. Kim; T. Dalhuisen; H. P. Tummala; R. Tibúrcio; L. Zemelko; G. M. Borgo; S. S. Singh; K. Schwartz; M. Deswal; M. C. Williams; R. Hoh; M. Shimoda; S. Narpala; L. Serebryannyy; M. Khalili; E. Vendrame; D. SenGupta; L. S. Whitmore; J. Tisoncik-Go; M. Gale; R. A. Koup; J. I. Mullins; B. K. Felber; G. N. Pavlakis; J. D. Reeves; C. J. Petropoulos; D. V. Glidden; M. H. Spitzer; L. Gama; M. Caskey; M. C. Nussenzweig; K. W. Chew; T. J. Henrich; S. A. Yukl; L. B. Cohn; S. G. Deeks; R. L. Rutishauser
Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates

灵长类动物中，生发中心克隆扩增和记忆B细胞对加强免疫接种的应答及其多样性

Cell Reports
IF6.9
2025-08-120
OA
Lachlan P. Deimel; Yoshiaki Nishimura; Gabriela S. Silva Santos; Viren A. Baharani; Brianna Hernandez; Thiago Y. Oliveira; Andrew J. MacLean; Marie Canis; Sadman Shawraz; Anna Gazumyan; Harald Hartweger; Paul D. Bieniasz; Theodora Hatziioannou; Malcolm A. Martin; Michel C. Nussenzweig
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses

墨西哥和巴西的人类抗体中和蜱传黄病毒

CELL REPORTS
IF6.9
2024-06-010
OA
Rincon, Tomas Cervantes; Kapoor, Tania; Keeffe, Jennifer R.; Simonelli, Luca; Hoffmann, Hans -Heinrich; Agudelo, Marianna; Jurado, Andrea; Peace, Avery; Lee, Yu E.; Gazumyan, Anna; Guidetti, Francesca; Cantergiani, Jasmine; Cena, Benedetta; Bianchini, Filippo; Tamagnini, Elia; Moro, Simone G.; Svoboda, Pavel; Costa, Federico; Reis, Mitermayer G.; Ko, Albert I.; Fallon, Brian A.; Avila-Rios, Santiago; Reyes-Teran, Gustavo; Rice, Charles M.; Nussenzweig, Michel C.; Bjorkman, Pamela J.; Ruzek, Daniel; Varani, Luca; Macdonald, Margaret R.; Robbiani, Davide F.
Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV
PHARMACEUTICS
IF5.5
2024-04-273
OAAI
Mayer, Bryan T.; Zhang, Lily; Decamp, Allan C.; Yu, Chenchen; Sato, Alicia; Angier, Heather; Seaton, Kelly E.; Yates, Nicole; Ledgerwood, Julie E.; Mayer, Kenneth; Caskey, Marina; Nussenzweig, Michel; Stephenson, Kathryn; Julg, Boris; Barouch, Dan H.; Sobieszczyk, Magdalena E.; Edupuganti, Srilatha; Kelley, Colleen F.; Mcelrath, M. Juliana; Gelderblom, Huub C.; Pensiero, Michael; McDermott, Adrian; Gama, Lucio; Koup, Richard A.; Gilbert, Peter B.; Cohen, Myron S.; Corey, Lawrence; Hyrien, Ollivier; Tomaras, Georgia D.; Huang, Yunda
Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Subvariant Neutralization Following a Primary Vaccine Series of NVX-CoV2373 and BNT162b2 Monovalent Booster Vaccine
OPEN FORUM INFECTIOUS DISEASES
IF3.8
2024-01-031
OAAI
Babu, Tara M.; Shen, Xiaoying; Mcclelland, R. Scott; Wang, Zijun; Selke, Stacy; Wilkens, Chloe; Hauge, Kirsten A.; Mcclurkan, Christopher L.; Goecker, Erin; Laing, Kerry J.; Koelle, David M.; Greninger, Alexander L.; Nussenzweig, Michel C.; Montefiori, David C.; Corey, Lawrence; Wald, Anna
Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques
Science
IF45.8
2024-01-010
OA
So‐Yon Lim; Jina Lee; Christa Elyse Osuna; Pratik P. Vikhe; Dane R. Schalk; Elsa Chen; Emily J. Fray; Mithra R. Kumar; NANCY J. SCHULTZ‐DARKEN; Eva G. Rakasz; Saverio Capuano; Ruby A. Ladd; Hwi Min Gil; David T. Evans; Emily K. Jeng; Michael S. Seaman; Malcolm A. Martin; Christiaan Hendrik van Dorp; Alan S. Perelson; Hing C. Wong; Janet D'Angelo Siliciano; Robert F. Siliciano; Jeffrey T. Safrit; Douglas F. Nixon; Patrick Soon‐Shiong; Michel C. Nussenzweig; James B. Whitney
Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant- specific neutralizing antibodies
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-12-141
OAAI
Zang, Trinity; Kuffour, Edmund Osei; Baharani, Viren A.; Canis, Marie; Schmidt, Fabian; Da Silva, Justin; Lercher, Alexander; Chaudhary, Pooja; Hoffmann, Hans- Heinrich; Gazumyan, Anna; Miranda, Ileana C.; MacDonald, Margaret R.; Rice, Charles M.; Nussenzweig, Michel C.; Hatziioannou, Theodora; Bieniasz, Paul D.

研究方向

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M
Marina Caskey
H 指数:69论文数:171被引数:2.3万
A
Anna Gazumyan
H 指数:62论文数:134被引数:2.0万
T
Thiago Y. Oliveira
H 指数:59论文数:158被引数:2.1万
P
Pamela J. Björkman
H 指数:107论文数:526被引数:5.4万
M
Michael S. Seaman
H 指数:104论文数:426被引数:4.1万
M
Mila Janković
H 指数:49论文数:100被引数:1.2万
D
Davide F. Robbiani
H 指数:53论文数:109被引数:2.0万
C
Christian Gaebler
H 指数:57论文数:149被引数:1.9万
V
Víctor Ramos
H 指数:32论文数:80被引数:1.0万
P
Paul D. Bieniasz
H 指数:99论文数:334被引数:4.2万