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C

Christopher D. Scharer

Emory University School of Medicine

36H指数
225论文数
5.8K被引数
收录论文 103
发表时间
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Maternal HIV Exposure Is Associated With Transient Transcriptional Changes in Monocytes and Natural Killer Cells in Early Infancy母体HIV暴露与婴儿早期单核细胞和自然杀伤细胞的暂时性转录变化相关
errThe Journal of Infectious Diseases
IF0
err2026-09-22
err0
errOAAI
errChristopher D Scharer; Jaclyn N Escudero; Sakeenah L Hicks; Loren E Sasser; Arijita Subuddhi; Lisa Marie Cranmer; Wendy E Whatney; Jerphason Mecha; John Kinuthia; Jeremy M Boss; Sylvia M LaCourse; Grace C John-Stewart; Cheryl L Day; null
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Selective control of HLA-DRB1 and HLA-DQA1 transcription through DR/DQ super enhancer microelements通过DR/DQ超增强子微元件选择性调控HLA-DRB1和HLA-DQA1转录
errCell Reports
IF6.9
err2026-09-09
err0
errOAAI
errParimal Majumder; Joshua Lee; Royce Butler; Christopher D. Scharer; Jeremy M. Boss
err分享
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Xist RNA dependent and independent mechanisms regulate dynamic X chromosome inactivation in B lymphocytesXist RNA依赖和非依赖机制调控B淋巴细胞中X染色体失活的动态过程
errCell Reports
IF6.9
err2026-04-09
err0
errOAAI
errNatalie E. Toothacre; Kiara L. Rodríguez-Acevedo; Keenan J. Wiggins; Christopher D. Scharer; Montserrat C. Anguera
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Early-life B cell memory is archived in the mouse B-1 cell compartment and drives chronic lymphocytic leukemia-like disease早期B细胞记忆存储于小鼠B-1细胞群中，并驱动慢性淋巴细胞白血病样疾病。
errCell Reports
IF6.9
err2026-03-25
err0
errOAAI
errNiklas Segrén; Stefano Vergani; Joan Escrivà-Font; Giorgia Montano; Elena Boldrin; Selene Sodini; Konjit Getachew Muleta; Shamit Soneji; Christopher D. Scharer; Camila Rosat Consiglio; Joan Yuan
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Human lung CD8+ tissue-resident memory T cell-derived interferon-γ orchestrates subset-specific antiviral programming in airway epithelial cells人肺CD8+组织驻留记忆T细胞衍生的干扰素-γ调控气道上皮细胞中特定亚型的抗病毒程序
errImmunity
IF26.3
err2025-11-26
err0
errOAAI
errCameron L.R. Mattingly; Ariana R. Jimenez; M. Elliott Williams; Kirsten N. Kost; Laurel A. Lawrence; Thien Duy Chen; Sarah E. Michalets; Jenna L. Lobby; Yixel Soto-Vázquez; Kathryn M. Moore; Sakeenah L. Hicks; Shamika Danzy; Jennifer L. Elliott; Christopher D. Scharer; Alison Swaims-Kohlmeier; Anice C. Lowen; Aneesh Mehta; Jacob E. Kohlmeier
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Heterogeneity of in vitro generated primary human antibody secreting cells of Systemic Lupus Erythematosus (SLE) patients
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errDenslow, Ashley J.; Rosenberg, Alexander; Scharer, Christopher; Nguyen, Doan; Chen, Suki; Zhou, Fen; Jenks, Scott; Sanz, Ignacio; Lee, Frances Eun-Hyung; Lund, Frances E.; Zumaquero-Martinez, Esther C.
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Obesity disrupts cholesterol homeostasis to dysregulate VAT Treg subsets
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errLi, Chaoran; Elkins, Cody; Ye, Chengyu; Barragan, Luisa Cervantes; Wu, Tuoqi; Au-Yeung, Byron B.; Scharer, Christopher; Ford, Mandy L.; Kissick, Haydn
err分享
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Naturally occurring polymorphisms reveal the cis-regulatory architecture priming marginal zone B cell differentiation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errScharer, Christopher; Roman, Carly J.; Gupta, Mansi; Hicks, Sakeenah L.; George-Alexander, Lou-Ella
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ABC signature in partial recombination activating gene (RAG) deficiency and chronic TLR stimulation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errToth, Marta; Scharer, Christopher; van der Burg, Mirjam; Nagy, Laszlo; Czimmerer, Zsolt; Walter, Jolan E.
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Dissecting the transcriptional and epigenetic landscape of human antibody-secreting cells in blood and bone marrow long-lived plasma cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errAnis, Hira; Cabrera-Mora, Monica; Scharer, Christopher; Sanz, Ignacio; Gibson, Greg; Lee, Frances Eun-Hyung
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Irf1 regulates the homeostasis of pathogenic age-associated B cells (ABC) and antibody secreting cells (ASC) subsets in autoimmunity and inflammaging
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errOwiredu, Eddie-Williams; Peel, Jessica N.; Zumaquero-Martinez, Esther C.; Foote, Jeremy B.; Scharer, Christopher; Lund, Frances E.
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CXCR5 Signals Fine-Tune Dendritic Cell Transcription and Regulate TH2 DevelopmentCXCR5信号微调树突状细胞转录并调控TH2发育
errVaccines 2025, Vol. 13, Page 943
IF3.4
err2025-09-04
err0
errOAAI
errMiranda L. Curtiss; Natalia Ballesteros Benavides; Alexander F. Rosenberg; Christopher D. Scharer; Beatriz León; Frances E. Lund
err分享
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Single-Cell Transcriptomics Reveals Depletion and Dysregulation of Mycobacterium tuberculosis-Specific Th1 and Th17 Cells Early After Acquisition of Human Immunodeficiency Virus单细胞转录组学揭示人类免疫缺陷病毒获得后早期，结核分枝杆菌特异性Th1和Th17细胞的耗竭与失调。
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2025-07-01
err1
PREAI
errPearson, Rachel A.; Krish, Krista N.; Whatney, Wendy E.; Jaoko, Walter; Mandaliya, Kishor; Overbaugh, Julie; Graham, Susan M.; Mcclelland, R. Scott; Hicks, Sakeenah L.; Maurer, Jeffrey; Scharer, Christopher D.; Day, Cheryl L.
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Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets转录因子T-bet调节淋巴结和肺效应记忆B细胞亚群的维持和分化潜能。
errImmunity
IF26.3
err2025-06-21
err0
PREAI
errChristopher A. Risley; Michael D. Schultz; S. Rameeza Allie; Shanrun Liu; Jessica N. Peel; Anoma Nellore; Christopher F. Fucile; Christopher D. Scharer; Jeremy M. Boss; Troy D. Randall; Alexander F. Rosenberg; Frances E. Lund
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MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulationMHCII的减少不足以保护小鼠免受α-突触核蛋白诱导的退行性变化，且帕金森病的HLA基因座表现出表观遗传调控。
errSCIENTIFIC REPORTS
IF3.9
err2025-04-21
err0
errOAAI
errKline, Elizabeth M.; Jernigan, Janna E.; Scharer, Christopher D.; Maurer, Jeffrey; Hicks, Sakeenah L.; Herrick, Mary K.; Wallings, Rebecca L.; Kelly, Sean D.; Chang, Jianjun; Menees, Kelly B.; McFarland, Nikolaus R.; Boss, Jeremy M.; Tansey, Malu Gamez; Joers, Valerie
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Fgl2 regulates FcγRIIB+CD8+ T cell responses during infectionFgl2调节感染期间FcγRIIB+CD8+ T细胞的应答
errJCI INSIGHT
IF6.1
err2025-04-08
err0
errOAAI
errMorris, Anna B.; Adelman, Max W.; Bennion, Kelsey B.; Martinez, Catherine D.; McCook, Kem-Maria; Woodworth, Michael H.; Langelier, Charles R.; Rouphael, Nadine; Scharer, Christopher D.; Maier, Cheryl L.; Kraft, Colleen S.; Ford, Mandy L.
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The Microbial Metabolite δ-Valerobetaine Strengthens the Gut Epithelial Barrier微生物代谢物δ-缬草丙氨酸加强了肠道上皮屏障
erramerican journal of pathology
IF0
err2025-03-22
err0
PREAI
errLauren C. Askew; C. Anthony Gacasan; Maria E. Barbian; Jaclyn Weinberg; Liping Luo; Brian S. Robinson; Dean P. Jones; Christopher D. Scharer; Rheinallt M. Jones
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err收藏
An early precursor CD8+ T cell that adapts to acute or chronic viral infection适应急性或慢性病毒感染的早期前体CD8+ T细胞
errNATURE
IF48.5
err2025-01-08
err5
PREAI
errMcmanus, Daniel T.; Valanparambil, Rajesh M.; Medina, Christopher B.; Scharer, Christopher D.; Mcguire, Donald J.; Sobierajska, Ewelina; Hu, Yinghong; Chang, Daniel Y.; Wieland, Andreas; Lee, Judong; Nasti, Tahseen H.; Hashimoto, Masao; Ross, James L.; Prokhnevska, Nataliya; Cardenas, Maria A.; Gill, Amanda L.; Clark, Elisa C.; Abadie, Kathleen; Kumar, Arjun J.; Au-Yeung, Byron B.; Kueh, Hao Yuan; Kissick, Haydn T.; Ahmed, Rafi
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Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE (NOV, 10.1038/s41590-024-02010-9, 2024)
errNATURE IMMUNOLOGY
IF27.6
err2024-12-02
err0
errOAAI
errFaliti, Caterina E.; Van, Trinh T. P.; Anam, Fabliha A.; Cheedarla, Narayanaiah; Williams, M. Elliott; Mishra, Ashish Kumar; Usman, Sabeena Y.; Woodruff, Matthew C.; Kraker, Geoff; Runnstrom, Martin C.; Kyu, Shuya; Sanz, Daniel; Ahmed, Hasan; Ghimire, Midushi; Morrison-Porter, Andrea; Quehl, Hannah; Haddad, Natalie S.; Chen, Weirong; Cheedarla, Suneethamma; Neish, Andrew S.; Roback, John D.; Antia, Rustom; Hom, Jennifer; Tipton, Christopher M.; Lindner, John M.; Ghosn, Eliver; Khurana, Surender; Scharer, Christopher D.; Khosroshahi, Arezou; Lee, F. Eun-Hyung; Sanz, Ignacio
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Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα plus intraepithelial T cells膳食纤维促进肠上皮细胞抗原递呈及小肠CD4 CD8αα + 上皮内T细胞的发育
errMUCOSAL IMMUNOLOGY
IF7.6
err2024-12-01
err0
errOAAI
errRodriguez-Marino, Naomi; Royer, Charlotte J.; Rivera-Rodriguez, Dormarie E.; Seto, Emma; Gracien, Isabelle; Jones, Rheinallt M.; Scharer, Christopher D.; Gracz, Adam D.; Cervantes-Barragan, Luisa
err分享
err收藏

研究方向

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