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I

Igñacio Sanz

Emory University
H指数:46
被引数:1.0万

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Multi-omics profiling of primary human B cells activated via distinct stimuli

通过不同刺激激活的原代人类B细胞的多组学分析

Nature Communications
IF15.7
2026-10-230
OAAI
Vitor R. C. Aguiar; Marcella E. Franco; Nada Abdel Aziz; Daniela Fernandez-Salinas; Marcos Chiñas; Mariasilvia Colantuoni; Qian Xiao; Nicolaj Hackert; Yifei Liao; Rodrigo Cervantes-Diaz; Marc Todd; Brian Wauford; Alex Wactor; Vaishali Prahalad; Raquel Laza-Briviesca; Roxane Darbousset; Qiang Wang; Scott Jenks; Kevin S. Cashman; Esther Zumaquero; Zhu Zhu; Junning Case; Paloma Cejas; Miguel Gomez; Hannah Ainsworth; Miranda Marion; Mehdi Benamar; Pui Lee; Lauren Henderson; Margaret H. Chang; Kevin Wei; Henry Long; Carl D. Langefeld; Ashley D. Sanders; Benjamin E. Gewurz; Ignacio Sanz; Jeffrey A. Sparks; Esra Meidan; Peter A. Nigrovic; Maria Gutierrez-Arcelus
Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells

针对IGHV4-34 b细胞受体的嵌合抗原受体T细胞特异性消除肿瘤性和自身免疫性b细胞

Science Translational Medicine
IF14.6
2026-02-040
PRE
Ivan J. Cohen; Audrey C. Bochi-Layec; Jean Lemoine; Scott Jenks; Pedram Bayat; Ki Hyun Kim; Huiwu Zhao; Ositadimma Ugwuanyi; Federico Stella; Guido Ghilardi; Giulia Gabrielli; Sarah McCuaig; Anastasia Iatrou; Elisavet Vlachonikola; Maria Karipidou; Eleni Bouziani; David Espie; Ranjani Ramasubramanian; Andreas Agathangelidis; Aditya Bhosale; Luca Paruzzo; Giovanni Medico; Bronte Kolar; Regina Bugrovsky; Puneeth Guruprasad; Li-Ping Wang; Jaryse Harris; Evgeny Arons; Yunlin Zhang; Raymone Pajarillo; Portia A. Kreiger; Chi-Ping Day; S. Cenk Sahinalp; Chih Hao Wu; Alessia Santi; Bria Fulmer; Marcos Cases; Matthew B. Palmer; Patrizia Porazzi; E. John Wherry; Robert J. Kreitman; Enrico Tiacci; Sokratis A. Apostolidis; Edward M. Behrens; Vijay Bhoj; Ignacio Sanz; Giorgio Inghirami; Stephen J. Schuster; Paolo Ghia; Kostas Stamatopoulos; Marco Ruella
Transient nasal anti-interferon autoantibodies predict better outcomes in COVID-19 infection
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Babcock, Benjamin R.; Kosters, Astrid; Eddins, Devon James; Sophia, Maria; Donaire, Baluyot; Sarvadhavabhatla, Sannidhi; Pae, Vivian; Beltran, Fiona; Murray, Victoria W.; Gill, Gurjot; Xie, Guorui; Dobosh, Brian S.; Giacalone, Vincent D.; Tirouvanziam, Rabindra M.; Ramonell, Richard Paul; Jenks, Scott; Sanz, Ignacio; Lee, Frances Eun-Hyung; Roan, Nadia R.; Lee, Sulggi A.; Ghosn, Eliver Eid Bou
A multiomics resource of B cell activation helps decipher disease pathogenesis
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Aguiar, Vitor R. C.; Franco, Marcella E.; Fernandez-Salinas, Daniela; Chinas, Marcos; Xiao, Qian; Hackert, Nicolaj; Colantuoni, Mariasilvia; Aziz, Nada Abdel; Todd, Marc; Wauford, Brian; Wactor, Alexandra; Prahalad, Vaishali; Laza Briviesca, Raquel; Darbousset, Roxane; Wang, Qiang; Banasiak, Emily; Jenks, Scott; Cashman, Kevin; Zumaquero-Martinez, Esther C.; Zhu, Zhu; Case, Junning; Cejas, Paloma; Gomez, Miguel; Benamar, Mehdi; Lee, Pui; Henderson, Lauren; Chang, Margaret H.; Wei, Kevin; Long, Henry; Langefeld, Carl; Sanz, Ignacio; Sparks, Jeffrey; Meidan, Esra; Nigrovic, Peter; Gutierrez-Arcelus, Maria
A roadmap for defining “extrafollicular” B cell responses

“extrafollicular” B细胞反应的定义路线图

Immunity
IF26.3
2025-09-220
PRE
Stephanie C. Eisenbarth; Facundo Batista; Jason Cyster; Rebecca Elsner; Garnett Kelsoe; Frances E. Lund; Shiv Pillai; Ignacio Sanz; Mark Shlomchik; Kai-Michael Toellner; Carola Vinuesa; Nicole Baumgarth
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE (NOV, 10.1038/s41590-024-02010-9, 2024)
NATURE IMMUNOLOGY
IF27.6
2024-12-020
OAAI
Faliti, Caterina E.; Van, Trinh T. P.; Anam, Fabliha A.; Cheedarla, Narayanaiah; Williams, M. Elliott; Mishra, Ashish Kumar; Usman, Sabeena Y.; Woodruff, Matthew C.; Kraker, Geoff; Runnstrom, Martin C.; Kyu, Shuya; Sanz, Daniel; Ahmed, Hasan; Ghimire, Midushi; Morrison-Porter, Andrea; Quehl, Hannah; Haddad, Natalie S.; Chen, Weirong; Cheedarla, Suneethamma; Neish, Andrew S.; Roback, John D.; Antia, Rustom; Hom, Jennifer; Tipton, Christopher M.; Lindner, John M.; Ghosn, Eliver; Khurana, Surender; Scharer, Christopher D.; Khosroshahi, Arezou; Lee, F. Eun-Hyung; Sanz, Ignacio
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE
NATURE IMMUNOLOGY
IF27.6
2024-11-121
OAAI
Faliti, Caterina E.; Van, Trinh T. P.; Anam, Fabliha A.; Cheedarla, Narayanaiah; Williams, M. Elliott; Mishra, Ashish Kumar; Usman, Sabeena Y.; Woodruff, Matthew C.; Kraker, Geoff; Runnstrom, Martin C.; Kyu, Shuya; Sanz, Daniel; Ahmed, Hasan; Ghimire, Midushi; Morrison-Porter, Andrea; Quehl, Hannah; Haddad, Natalie S.; Chen, Weirong; Cheedarla, Suneethamma; Neish, Andrew S.; Roback, John D.; Antia, Rustom; Hom, Jennifer; Tipton, Christopher M.; Lindner, John M.; Ghosn, Eliver; Khurana, Surender; Scharer, Christopher D.; Khosroshahi, Arezou; Lee, F. Eun-Hyung; Sanz, Ignacio
Transient anti-interferon autoantibodies in the airways are associated with recovery from COVID-19
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-11-060
PRE
Babcock, Benjamin R.; Kosters, Astrid; Eddins, Devon J.; Donaire, Maria Sophia Baluyot; Sarvadhavabhatla, Sannidhi; Pae, Vivian; Beltran, Fiona; Murray, Victoria W.; Gill, Gurjot; Xie, Guorui; Dobosh, Brian S.; Giacalone, Vincent D.; Tirouvanziam, Rabindra M.; Ramonell, Richard P.; Jenks, Scott A.; Sanz, Ignacio; Lee, F. Eun-Hyung; Roan, Nadia R.; Lee, Sulggi A.; Ghosn, Eliver E. B.
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination

mRNA疫苗接种后，SARS-CoV-2-specific浆细胞无法在骨髓长寿命区室中持久建立

NATURE MEDICINE
IF50
2024-09-272
OAAI
Nguyen, Doan C.; Hentenaar, Ian T.; Morrison-Porter, Andrea; Solano, David; Haddad, Natalie S.; Castrillon, Carlos; Runnstrom, Martin C.; Lamothe, Pedro A.; Andrews, Joel; Roberts, Danielle; Lonial, Sagar; Sanz, Ignacio; Lee, F. Eun-Hyung
Autoantibodies inhibit Plasmodium falciparum growth and are associated with protection from clinical malaria
IMMUNITY
IF26.3
2024-08-012
PRE
Hagadorn, Kelly A.; Peterson, Mary E.; Kole, Hemanta; Scott, Bethany; Skinner, Jeff; Diouf, Ababacar; Takashima, Eizo; Ongoiba, Aissata; Doumbo, Safiatou; Doumtabe, Didier; Li, Shanping; Sekar, Padmapriya; Yan, Mei; Zhu, Chengsong; Nagaoka, Hikaru; Kanoi, Bernard N.; Li, Quan-Zhen; Long, Carole; Long, Eric O.; Kayentao, Kassoum; Jenks, Scott A.; Sanz, Ignacio; Tsuboi, Takafumi; Traore, Boubacar; Bolland, Silvia; Miura, Kazutoyo; Crompton, Peter D.; Hopp, Christine S.
Factors associated with immune responses to SARS-CoV-2 vaccination in individuals with autoimmune diseases
JCI INSIGHT
IF6.1
2024-06-041
OA
Anderson, Erik; Powell, Michael; Yang, Emily; Kar, Ananya; Leung, Tung Ming; Sison, Cristina; Steinberg, Rebecca; Mims, Raven; Choudhury, Ananya; Espinosa, Carlo; Zelmanovich, Joshua; Okoye, Nkemakonam C.; Choi, Eun Jung; Marder, Galina; Narain, Sonali; Gregersen, Peter K.; Mackay, Meggan; Diamond, Betty; Levy, Todd; Zanos, Theodoros P.; Khosroshahi, Arezou; Sanz, Ignacio; Prak, Eline T. Luning; Bar-Or, Amit; Merrill, Joan; Arriens, Cristina; Pardo, Gabriel; Guthridge, Joel; James, Judith; Payne, Aimee; Utz, Paul J.; Boss, Jeremy M.; Aranow, Cynthia; Davidson, Anne
Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus
Nature Communications
IF15.7
2024-03-010
OAAI
Weirong Chen; So-Hee Hong; Scott A. Jenks; Fabliha A. Anam; Christopher M. Tipton; Matthew C. Woodruff; Jennifer R. Hom; Kevin S. Cashman; Caterina Elisa Faliti; Xiaoqian Wang; Shuya Kyu; Chungwen Wei; Christopher D. Scharer; Tian Mi; Sakeenah Hicks; Louise Hartson; Doan C. Nguyen; Arezou Khosroshahi; Saeyun Lee; Youliang Wang; Regina Bugrovsky; Yusho Ishii; F. Eun-Hyung Lee; Ignacio Sanz
Patients on mepolizumab, benralizumab, or dupilumab have diminished post-vaccination antibody and B cell responses to SARS-CoV-2.
EUROPEAN RESPIRATORY JOURNAL
IF21
2023-10-270
PRE
Lamothe, Pedro; Runnstrom, Martin; Faliti, Katia; Cheedrala, Narayanaiah; Moreno, Alberto; Suthar, Mehul; Nahata, Rishika; Ravindran, Mayuran; Morrison-Porter, Andrea; Ramonell, Richard; Woodruff, Matthew; Swerlick, Robert; Swenson, Colin; Polito, Carmen; Neveu, Wendy; Smirnova, Natalia; Kim, Caroline; Hentenaar, Ian; Kyu, Shuya; Guo, Zhenxing; Wu, Hao; Haddad, Natalie; Park, Jiwon; Daiss, John; Cheedarla, Suneetha; Neish, Andrew; Roback, John; Sharma, Sunita; Holguin, Fernando; Sanz, Ignacio; Lee, Frances Eun-Hyung
Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID
NATURE COMMUNICATIONS
IF15.7
2023-07-1449
OAAI
Woodruff, Matthew C.; Bonham, Kevin S.; Anam, Fabliha A.; Walker, Tiffany A.; Faliti, Caterina E.; Ishii, Yusho; Kaminski, Candice Y.; Ruunstrom, Martin C.; Cooper, Kelly Rose; Truong, Alexander D.; Dixit, Adviteeya N.; Han, Jenny E.; Ramonell, Richard P.; Haddad, Natalie S.; Rudolph, Mark E.; Yalavarthi, Srilakshmi; Betin, Viktoria; Natoli, Ted; Navaz, Sherwin; Jenks, Scott A.; Zuo, Yu; Knight, Jason S.; Khosroshahi, Arezou; Lee, F. Eun-Hyung; Sanz, Ignacio
Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses

通过单细胞分析了解人骨髓浆细胞成熟和存活途径的异质性

CELL REPORTS
IF6.9
2023-07-0117
OAAI
Duan, Meixue; Nguyen, Doan C.; Joyner, Chester J.; Saney, Celia L.; Tipton, Christopher M.; Andrews, Joel; Lonial, Sagar; Kim, Caroline; Hentenaar, Ian; Kosters, Astrid; Ghosn, Eliver; Jackson, Annette; Knechtle, Stuart; Maruthamuthu, Stalinraja; Chandran, Sindhu; Martin, Tom; Rajalingam, Raja; Vincenti, Flavio; Breeden, Cynthia; Sanz, Ignacio; Gibson, Greg; Lee, F. Eun-Hyung

研究方向

暂未获取到该数据
F
F. Eun‐Hyung Lee
H 指数:30论文数:104被引数:4,807
S
Scott A. Jenks
H 指数:24论文数:55被引数:5,240
M
Matthew C. Woodruff
H 指数:27论文数:95被引数:5,798
D
Doan C. Nguyen
H 指数:26论文数:64被引数:3,880
C
Christopher M. Tipton
H 指数:30论文数:76被引数:6,353
K
Kevin S. Cashman
H 指数:19论文数:43被引数:3,768
C
Christopher D. Scharer
H 指数:36论文数:227被引数:6,065
C
Chungwen Wei
H 指数:28论文数:44被引数:5,913
N
Natalie S. Haddad
H 指数:13论文数:55被引数:2,632
J
Jeremy M. Boss
H 指数:75论文数:299被引数:1.8万