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D

Daesik Kim

Sungkyunkwan University School of Medicine

37H指数
173论文数
1.1W被引数
收录论文 57
发表时间
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Structure-guided engineering of AI-derived adenine base editors for nuclear and mitochondrial DNA editing基于结构的AI衍生腺嘌呤碱基编辑器在核DNA和线粒体DNA编辑中的工程设计
errNucleic Acids Research
IF13.1
err2026-07-20
err0
errOAAI
errHye-Yeon Hwang; Nabukenya Mariam; Jiyeon Kweon; Hwalin Yi; Gayoung Jang; Jiyoo Roh; Kayeong Lim; Jae-Hyun Park; Yongsub Kim; Daesik Kim; null
err分享
err收藏
Metanephrine-secreting adrenocortical carcinoma in a dog with clinical and biochemical features suggestive of pheochromocytoma犬肾上腺皮质癌分泌去甲肾上腺素，具有提示嗜铬细胞瘤的临床和生化特征
errJournal of Veterinary Internal Medicine
IF2.2
err2026-05-01
err0
PREAI
errKim, Daesik; Park, Seol-Gi; Moon, Joungsun; O, I-se; Kim, Min Su
err分享
err收藏
Herpes simplex virus 1 harboring poly(T) DNA sequences as a key ligand for AIM2 inflammasome activation and host defense单纯疱疹病毒1携带聚(T) DNA序列作为AIM2炎性体活化和宿主防御的关键配体
errNature Communications
IF15.7
err2026-04-13
err0
errOAAI
errSuHyeon Oh; Jueun Oh; Kyeongchan Im; Tae Hyoung Kim; Jihye Lee; Kihye Shin; Nabukenya Mariam; Cheong Seok; Jaewoo Park; GyeongJu Yu; Hayeon Kim; Suhyun Kim; Seyun Shin; Jinwoo Gil; Sehee Park; Yoon-Seok Chung; Daesik Kim; Young Ki Choi; Eui Tae Kim; Joo Sang Lee; SangJoon Lee
err分享
err收藏
eVLP-Mediated Cas9 Delivery for Preventing IBMIR in Islet TransplantationeVLP介导的Cas9递送以预防胰岛移植中的IBMIR
errSmall
IF12.1
err2025-11-18
err0
errOAAI
errManju Shrestha; Yeonji Kim; Subin Park; Hu-Lin Jiang; Jae-Young Lee; Daesik Kim; Jee-Heon Jeong
err分享
err收藏
AIM2 drives inflammatory cell death and monkeypox pathogenesisAIM2驱动炎症性细胞死亡和猴痘致病过程
errCellular & Molecular Immunology
IF19.8
err2025-11-12
err0
errOAAI
errJueun Oh; Yun-Ho Hwang; Jihye Lee; Cheong Seok; SuHyeon Oh; Hye Yoon Kim; Nabukenya Mariam; Jaeyoung Ahn; GyeongJu Yu; Jaewoo Park; Hayeon Kim; Suhyun Kim; Seyun Shin; Min-Chul Jung; Jinwoo Gil; Joo Sang Lee; Young Ki Choi; Dokeun Kim; Daesik Kim; You-Jin Kim; SangJoon Lee
err分享
err收藏
Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration工程化病毒样颗粒组装的Vegfa靶向Cas9核糖核蛋白治疗减轻了湿性年龄相关性黄斑变性中的新生血管形成
errGenome Biology
IF9.4
err2025-10-11
err0
errOAAI
errJun Wu; Hyewon Jang; Hyunjong Kwak; Minchae Son; Weiyan Jiang; Hye-Yeon Hwang; Dong Hyun Jo; Daesik Kim; Hyongbum Henry Kim; Jeong Hun Kim
err分享
err收藏
Single-Cell RNA Analysis Reveals Reduced Frequency and Activity of CXCR5+ Atypical Memory B Cells in Islet Xenotransplantation Treated With Clinically Applicable Immunosuppressants Including Belimumab单细胞RNA分析揭示：在经临床适用免疫抑制剂（包括Belimumab）治疗的小鼠胰岛异种移植中，CXCR5+非典型记忆B细胞的频率和活性降低。
errXenotransplantation
IF4.1
err2025-09-18
err0
errOAAI
errYuji Lee; Ji Hwan Moon; Hyun Je Kim; Daesik Kim; Yong-Hee Kim; Jong-Min Kim; Chung-Gyu Park
err分享
err收藏
High−efficiency base editing for nuclear and mitochondrial DNA with an optimized DYW−like deaminase高效碱基编辑用于核DNA和线粒体DNA，并使用优化的DYW−like脱氨酶
errMolecular Therapy
IF12
err2025-08-08
err0
errOAAI
errJiyeon Kweon; Soomin Park; Mi Yeon Jeon; Kayeong Lim; Gayoung Jang; An-Hee Jang; Minyoung Lee; Cheong Seok; Chaeyeon Lee; Subin Park; Jiseong Ahn; JiYoon Jang; Naheun Kim; Young Hoon Sung; Daesik Kim; Yongsub Kim
err分享
err收藏
Four germline POLH variants, including two found in skin tumors, impair DNA polymerase η function and cellular tolerance to UV radiation and cisplatin四种生殖系POLH变异，包括在皮肤肿瘤中发现的两种，损害DNA聚合酶η功能以及细胞对紫外线辐射和顺铂的耐受性。
errCHEMICO-BIOLOGICAL INTERACTIONS
IF5.4
err2025-05-27
err0
PREAI
errHong, Jin-Kyung; Yeom, Mina; Hwang, Hye-Yeon; Mun, Eunji; Woo, Jae-Hyeon; Kim, Yeho; Shin, Joo-Ho; Lee, Yunjong; Kim, Daesik; Guengerich, F. Peter; Choi, Jeong-Yun
err分享
err收藏
In vivo adenine base editing rescues adrenoleukodystrophy in a humanized mouse model
errMOLECULAR THERAPY
IF12
err2024-07-01
err1
PREAI
errGopalappa, Ramu; Lee, MinYoung; Kim, Globinna; Jung, Eul Sik; Lee, Hanahrae; Hwang, Hye-Yeon; Lee, Jong Geol; Kim, Su Jung; Yoo, Hyun Ju; Sung, Young Hoon; Kim, Daesik; Baek, In-Jeoung; Kim, Hyongbum Henry
err分享
err收藏
CRISPR-based editing strategies to rectify EYA1 complex genomic rearrangement linked to haploinsufficiency基于CRISPR的编辑策略可纠正与单倍体不足相关的EYA1复杂基因组重排
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2024-06-01
err2
errOAAI
errYi, Hwalin; Yun, Yejin; Choi, Won Hoon; Hwang, Hye-Yeon; Cha, Ju Hyuen; Seok, Heeyoung; Song, Jae-Jin; Lee, Jun Ho; Lee, Sang-Yeon; Kim, Daesik
err分享
err收藏
Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-04-25
err0
errOAAI
errHwang, Hye-Yeon; Gim, Dongmin; Yi, Hwalin; Jung, Hyewon; Lee, Jaecheol; Kim, Daesik
err分享
err收藏
Advancing therapeutic interventions for NUT carcinoma: Orchestrating the precision of CRISPR/Cas9-mediated NUTM1 suppression and synergistic ADC strategies
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errChoi, Juyoung; Yi, Hwa Lin; Park, Hee Geon; Lee, Misook; Kim, Daesik; Hong, Sung Youl; Shin, Young Kee; Choi, Yoon-la
err分享
err收藏
β-arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4
errCELL DEATH & DISEASE
IF9.6
err2023-07-13
err10
errOAAI
errKim, Ji Young; Shin, Ji Hye; Kim, Mi-Jeong; Kang, Yeeun; Lee, Ji Su; Son, Juhee; Jeong, Soo-Kyung; Kim, Daesik; Kim, Duk-Hwan; Chun, Eunyoung; Lee, Ki-Young
err分享
err收藏
FFAR2 antagonizes TLR2-and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB
errCELL AND BIOSCIENCE
IF6.2
err2023-06-07
err9
errOAAI
errKim, Mi-Jeong; Kim, Ji Young; Shin, Ji Hye; Kang, Yeeun; Lee, Ji Su; Son, Juhee; Jeong, Soo-Kyung; Kim, Daesik; Kim, Duk-Hwan; Chun, Eunyoung; Lee, Ki-Young
err分享
err收藏
A 17.6-Bit 800-SPS Energy-Efficient Read-Out IC With Input Impedance Boosting
errIEEE SENSORS JOURNAL
IF4.5
err2023-05-01
err4
PREAI
errPark, Junyoung; Kim, Wooyoung; Kim, Daesik; Lee, Dongkeon; Hong, Yongtaek; Kim, Suhwan; Rhee, Jooyeol
err分享
err收藏
DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-04-28
err12
errOAAI
errSeo, Jung Hwa; Shin, Jeong Hong; Lee, Junwon; Kim, Daesik; Hwang, Hye-Yeon; Nam, Bae-Geun; Lee, Jinu; Kim, Hyongbum Henry; Cho, Sung-Rae
err分享
err收藏
Targeted genomic translocations and inversions generated using a paired prime editing strategy
errMOLECULAR THERAPY
IF12
err2023-01-01
err26
errOAAI
errKweon, Jiyeon; Hwang, Hye-Yeon; Ryu, Haesun; Jang, An-Hee; Kim, Daesik; Kim, Yongsub
err分享
err收藏
Expanded targeting scope of LbCas12a variants allows editing of multiple oncogenic mutations
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2022-12-01
err10
errOAAI
errChoi, Eunyoung; Hwang, Hye-Yeon; Kwon, Eunji; Kim, Daesik; Koo, Taeyoung
err分享
err收藏
Electronic Skin Based on a Cellulose/Carbon Nanotube Fiber Network for Large-Area 3D Touch and Real-Time 3D Surface Scanning
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2021-10-28
err22
PREAI
errKim, Daesik; Lee, Dong Keon; Yoon, Jinsu; Hahm, Donghyo; Lee, Byeongmoon; Oh, Eunho; Kim, Geonhee; Seo, Jiseok; Kim, Hanul; Hong, Yongtaek
err分享
err收藏

研究方向

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合作学者
合作期刊
F
F. Peter Guengerich
H 指数: 140 · 论文数: 1.2K
S
Seung Up Kim
H 指数: 99 · 论文数: 1.2K
J
Jin‐Soo Kim
H 指数: 89 · 论文数: 614
M
Matthias Schlesner
H 指数: 72 · 论文数: 448
Y
Yoon‐La Choi
H 指数: 71 · 论文数: 507
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