D. Michiel Pegtel - Publications, H-index & Citations

D. Michiel Pegtel

amsterdam umc location vrije universiteit amsterdam

50H指数

172论文数

2.8W被引数

收录论文 69

发表时间

Small and Large Extracellular Vesicles in Circulation of Diffuse Large B-Cell Lymphoma Patients Originate From Different Cell Types of the Tumor Microenvironment 弥漫性大B细胞淋巴瘤患者循环中的小型和大型外泌体源自肿瘤微环境中的不同细胞类型

Journal of Extracellular Vesicles

IF14.5

2026-03-26

OAAI

Filippo Maltoni; Steven Wang; Mischa. F. B. Steketee; Cristina A. Gómez-Martín; Esther E. E. Drees; Federica Morelli; Leontien Bosch; Monique van Eijndhoven; Gert Jan Timmers; Ilse Houtenbos; Josée M. Zijlstra; Xiaofei Ye; Qiang Pan-Hammarström; Martine E. D. Chamuleau; Pier Luigi Zinzani; Yongsoo Kim; Lucia Catani; Dirk Michiel Pegtel

Mesenchymal Colorectal Cancers Secrete Vesicles With Unique Cargo That Can Be Used for Liquid Biopsy Based Diagnostics 间充质结直肠癌分泌含有独特负载的囊泡，可用于基于液体活检的诊断。

Journal of Extracellular Vesicles

IF14.5

2025-10-30

OAAI

Paris J. Asif; Lauri H. Borghuis; Sander R. van Hooff; Anita E. Grootemaat; Monique A. J. van Eijndhoven; Johan de Rooij; Nils J. Groenewegen; Jennifer Perez Boza; Onno Kranenburg; Inne H. M. Borel Rinkes; Cristina Gómez-Martín; Hans F. M. Pruijt; Nicole N. van der Wel; Arezo Torang; Tineke E. Buffart; D. Michiel Pegtel; Jan Paul Medema

Matrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI Kapustin, A.N.; Tsakali, S.S.; Whitehead, M.; Chennell, G.; Wu, M.Y.; Molenaar, C.; Kutikhin, A.; Chen, Y.; Ahmad, S.; Bogdanov, L.; et al. 矩阵相关细胞外囊泡通过呈现胶原VI调节人平滑肌细胞的黏附和方向性。Elife 2025, 12, RP90375. [Google Scholar] [CrossRef] [PubMed]

ELIFE

IF0

2025-09-30

PREAI

Kapustin, Alexander N.; Tsakali, Sofia Serena; Whitehead, Meredith; Chennell, George; Wu, Meng-Ying; Molenaar, Chris; Kutikhin, Anton; Chen, Yimeng; Ahmad, Sadia; Bogdanov, Leo; Sinitsky, Maxim; Rubina, Kseniya; Clayton, Aled; Verweij, Frederik J.; Pegtel, Dirk Michiel; Zingaro, Simona; Lobov, Arseniy; Zainullina, Bozhana; Owen, Dylan; Parsons, Maddy; Cheney, Richard E.; Warren, Derek T.; Humphries, Martin James; Iskratsch, Thomas; Holt, Mark; Shanahan, Catherine M.

Circulating extracellular vesicle isomiR signatures predict therapy response in patients with multiple myeloma 循环外泌体异构miRNA特征可预测多发性骨髓瘤患者的治疗反应

Cell Reports Medicine

IF10.6

2025-09-16

OAAI

Cristina Gómez-Martín; Esther E.E. Drees; Monique A.J. van Eijndhoven; Nils J. Groenewegen; Steven Wang; Sandra A.W.M. Verkuijlen; Jan R.T. van Weering; Ernesto Aparicio-Puerta; Leontien Bosch; Kris A. Frerichs; Christie P.M. Verkleij; Marie J. Kersten; Josée M. Zijlstra; Daphne de Jong; Catharina G.M. Groothuis-Oudshoorn; Michael Hackenberg; Johan R. de Rooij; Niels W.C.J. van de Donk; D. Michiel Pegtel

Integrating Clinical Variables, Radiomics, and Tumor-derived Cell-Free DNA for Enhanced Prediction of Resectable Esophageal Adenocarcinoma Outcomes 整合临床变量，放射组学和肿瘤衍生的细胞游离DNA，以增强可切除食管腺癌预后的预测

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2025-03-01

OAAI

van den Ende, Tom; Kuijper, Steven C.; Widaatalla, Yousif; Noortman, Wyanne A.; van Velden, Floris H. P.; Woodruff, Henry C.; van der Pol, Ymke; Moldovan, Norbert; Pegtel, D. Michiel; Derks, Sarah; Bijlsma, Maarten F.; Mouliere, Florent; de Geus-Oei, Lioe-Fee; Lambin, Philippe; van Laarhoven, Hanneke W. M.

Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes 缺氧和tnf-α 调节人诱导多能干细胞来源心肌细胞的胞外囊泡释放

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2024-11-07

OAAI

Viola, Margarida; Bebelman, Maarten P.; Maas, Renee G. C.; de Voogt, Willemijn S.; Verweij, Frederik J.; Seinen, Cor S.; de Jager, Saskia C. A.; Vader, Pieter; Pegtel, Dirk Michiel; Sluijter, Joost Petrus Gerardus

Turning the tide in aggressive lymphoma: liquid biopsy for risk-adapted treatment strategies

Trends in Molecular Medicine

IF13.8

2024-07-01

PREAI

Wang, Steven; Mouliere, Florent; Pegtel, D. Michiel; Chamuleau, Martine E. D.

Multi-modal cell-free DNA genomic and fragmentomic patterns enhance cancer survival and recurrence analysis

CELL REPORTS MEDICINE

IF10.6

2024-01-01

OAAI

Moldovan, Norbert; Pol, Ymke van der; Ende, Tom van den; Boers, Dries; Verkuijien, Sandra; Creemers, Aafke; Ramaker, Jip; Vu, Trang; Bootsma, Sanne; Lenos, Kristiaan J.; Vermeulen, Louis; Fransen, Marieke F.; Pegtel, Michiel; Bahce, Idris; van Laarhoven, Hanneke; Mouliere, Florent

Real-time analysis of the cancer genome and fragmentome from plasma and urine cell-free DNA using nanopore sequencing 使用纳米孔测序实时分析血浆和尿液中无细胞DNA的癌症基因组和片段组

EMBO MOLECULAR MEDICINE

IF8.3

2023-11-09

OAAI

van Der Pol, Ymke; Tantyo, Normastuti Adhini; Evander, Nils; Hentschel, Anouk E.; Wever, Birgit M. M.; Ramaker, Jip; Bootsma, Sanne; Fransen, Marieke F.; Lenos, Kristiaan J.; Vermeulen, Louis; Schneiders, Famke L.; Bahce, Idris; Nieuwenhuijzen, Jakko A.; Steenbergen, Renske D. M.; Pegtel, D. Michiel; Moldovan, Norbert; Mouliere, Florent

The landscape of cell-free mitochondrial DNA in liquid biopsy for cancer detection

GENOME BIOLOGY

IF9.4

2023-10-12

OAAI

van der Pol, Ymke; Moldovan, Norbert; Ramaker, Jip; Bootsma, Sanne; Lenos, Kristiaan J.; Vermeulen, Louis; Sandhu, Shahneen; Bahce, Idris; Pegtel, D. Michiel; Wong, Stephen Q.; Dawson, Sarah-Jane; Chandrananda, Dineika; Mouliere, Florent

Genome-wide and panel-based cell-free DNA characterization of patients with resectable esophageal adenocarcinoma

JOURNAL OF PATHOLOGY

IF5.2

2023-08-24

OAAI

van den Ende, Tom; van der Pol, Ymke; Creemers, Aafke; Moldovan, Norbert; Boers, Dries; van Berge Henegouwen, Mark, I; Hulshof, Maarten C. C. M.; Cillessen, Saskia A. G. M.; van Grieken, Nicole C. T.; Pegtel, D. Michiel; Derks, Sarah; Bijlsma, Maarten F.; Mouliere, Florent; van Laarhoven, Hanneke W. M.

NORMSEQ: a tool for evaluation, selection and visualization of RNA-Seq normalization methods

NUCLEIC ACIDS RESEARCH

IF13.1

2023-05-22

OAAI

Scheepbouwer, Chantal; Hackenberg, Michael; van Eijndhoven, Monique A. J.; Gerber, Alan; Pegtel, Michiel; Gomez-Martin, Cristina

Reassessment of miRNA variant (isomiRs) composition by small RNA sequencing

CELL REPORTS METHODS

IF4.5

2023-05-01

OAAI

Gomez-Martin, Cristina; Aparicio-Puerta, Ernesto; Eijndhoven, Monique A. J. van; Medina, Jose M.; Hackenberg, Michael; Pegtel, Michiel

Platelet removal from human blood plasma improves detection of extracellular vesicle-associated miRNA

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2023-02-14

OAAI

Bracht, Jillian W. P.; Los, Mandy; van Eijndhoven, Monique A. J.; Bettin, Britta; van der Pol, Edwin; Pegtel, D. Michiel; Nieuwland, Rienk

ER membrane contact sites support endosomal small GTPase conversion for exosome secretion

JOURNAL OF CELL BIOLOGY

IF6.4

2022-09-22

OAAI

Verweij, Frederik J.; Bebelman, Maarten P.; George, Anna E.; Couty, Mickael; Becot, Anais; Palmulli, Roberta; Heiligenstein, Xavier; Sires-Campos, Julia; Raposo, Graca; Pegtel, Dirk Michiel; van Niel, Guillaume

Blood-based Monitoring of Relapsed/Refractory Hodgkin Lymphoma Patients Predict Responses to Anti-PD-1 Treatment

HEMASPHERE

IF14.6

2022-07-01

OAAI

Drees, Esther E. E.; Jauw, Yvonne W. S.; van Dijk, Erik; Borchmann, Sven; Verkuijlen, Sandra A. W. M.; Stathi, Phylicia; Groenewegen, Nils J.; Hijmering, Nathalie J.; Berry, Daniella R. A. I.; Meershoek, Eric J.; Hoogmoed, Danielle; Kwakman, Anne; Molenaar, Tessa J.; Pegtel, Dirk M.; Ylstra, Bauke; de Jong, Daphne; Zijlstra, Josee M.; Roemer, Margaretha G. M.

sRNAbench and sRNAtoolbox 2022 update: accurate miRNA and sncRNA profiling for model and non-model organisms

NUCLEIC ACIDS RESEARCH

IF13.1

2022-05-12

OAAI

Aparicio-Puerta, Ernesto; Gomez-Martin, Cristina; Giannoukakos, Stavros; Maria Medina, Jose; Scheepbouwer, Chantal; Garcia-Moreno, Adrian; Carmona-Saez, Pedro; Fromm, Bastian; Pegtel, Michiel; Keller, Andreas; Antonio Marchal, Juan; Hackenberg, Michael

The Effect of Preanalytical and Physiological Variables on Cell-Free DNA Fragmentation

CLINICAL CHEMISTRY

IF6.3

2022-03-16

OAAI

van der Pol, Ymke; Moldovan, Norbert; Verkuijlen, Sandra; Ramaker, Jip; Boers, Dries; Onstenk, Wendy; de Rooij, Johan; Bahce, Idris; Pegtel, D. Michiel; Mouliere, Florent

PCR-Free Shallow Whole Genome Sequencing for Chromosomal Copy Number Detection from Plasma of Cancer Patients Is an Efficient Alternative to the Conventional PCR-Based Approach

JOURNAL OF MOLECULAR DIAGNOSTICS

IF3.4

2021-11-01

OAAI

Beagan, Jamie J.; Drees, Esther E. E.; Stathi, Phylicia; Eijk, Paul P.; Meulenbroeks, Laura; Kessler, Floortje; Middeldorp, Jaap M.; Pegtel, D. Michiel; Zijlstra, Josee M.; Sie, Daoud; Heideman, Danielle A. M.; Thunnissen, Erik; Smit, Linda; de Jong, Daphne; Mouliere, Florent; Ylstra, Bauke; Roemer, Margaretha G. M.; van Dijk, Erik

In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin's lymphoma and facilitates ultrasensitive residual disease detection

MED

IF11.8

2021-10-01

OAAI

Sobesky, Sophia; Mammadova, Laman; Cirillo, Melita; Drees, Esther E. E.; Mattlener, Julia; Doerr, Helge; Altmueller, Janine; Shi, Zhiyuan; Broeckelmann, Paul J.; Weiss, Jonathan; Kreissl, Stefanie; Sasse, Stephanie; Ullrich, Roland T.; Reinke, Sarah; Klapper, Wolfram; Gerhard-Hartmann, Elena; Rosenwald, Andreas; Roemer, Margaretha G. M.; Nuernberg, Peter; Hagenbeek, Anton; Zijlstra, Josee M.; Pegtel, Dirk Michiel; Engert, Andreas; Borchmann, Peter; von Tresckow, Bastian; Borchmann, Sven

研究方向