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T

Todd R. Golub

broad institute
H指数:176
被引数:26.7万

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Author Correction: Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors

作者更正：基因组规模的空间映射揭示霍奇金淋巴瘤微环境中的肿瘤细胞存活因子

Nature Communications
IF15.7
2026-05-290
OAAI
Vignesh Shanmugam; Neriman Tokcan; Daniel Chafamo; Sean Sullivan; Mehdi Borji; Haley Martin; Gail Newton; Naeem Nadaf; Saoirse Hanbury; Irving Barrera; Dylan Cable; Jackson Weir; Orr Ashenberg; Geraldine Pinkus; Scott Rodig; Caroline Uhler; Evan Macosko; Margaret Shipp; Abner Louissaint; Fei Chen; Todd R. Golub
Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity

唾液酸化的CD43形成一种糖免疫屏障，该屏障可抑制抗白血病免疫。

Science
IF45.8
2026-04-090
PRE
Jooho Chung; Mounica Vallurupalli; Sarah Noel; Gail Schor; Sofia Mrowka; Ilario Scapozza; Zelalem Demere; Sachin V. Kammula; Margaret Hu; Sarah Y. Kim; YuhJong Liu; Celeste Nobrega; Jonathan J. Perera; Ewa Wrona; Collins K. Cheruiyot; Yunkang Lin; David W. Wu; Maria Saberi; Aidan Cruickshank; Elliot C. Woods; Cun Lan Chuong; Filippo Birocchi; Ashwin V. Kammula; Omar I. Avila; Nelson Knudsen; Mustafa Kocak; John G. Doench; Dean Procter; Lindsey Thornton; Andrew M. Brunner; Eric Winer; Daniel J. DeAngelo; Jacqueline S. Garcia; Richard M. Stone; Russell W. Jenkins; Marcela V. Maus; Timothy A. Graubert; Kathleen B. Yates; Todd R. Golub; Robert T. Manguso
Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors

基因组规模的空间图谱绘制揭示了霍奇金淋巴瘤微环境中的肿瘤细胞存活因子

Nature Communications
IF15.7
2025-12-200
OAAI
Vignesh Shanmugam; Neriman Tokcan; Daniel Chafamo; Sean Sullivan; Mehdi Borji; Haley Martin; Gail Newton; Naeem Nadaf; Saoirse Hanbury; Irving Barrera; Dylan Cable; Jackson Weir; Orr Ashenberg; Geraldine Pinkus; Scott Rodig; Caroline Uhler; Evan Macosko; Margaret Shipp; Abner Louissaint; Fei Chen; Todd R. Golub
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models
NATURE CANCER
IF28.5
2024-08-233
OAAI
Rauh, Ulrike; Wei, Guo; Serrano-Wu, Michael; Kosmidis, Georgios; Kaulfuss, Stefan; Siegel, Franziska; Thede, Kai; Mcfarland, James; Lemke, Christopher T.; Werbeck, Nicolas; Nowak-Reppel, Katrin; Pilari, Sabine; Menz, Stephan; Ocker, Matthias; Zhang, Weiqun; Davis, Kyle; Poncet-Montange, Guillaume; Roth, Jennifer; Daniels, Douglas; Kaushik, Virendar K.; Hubbard, Brian; Ziegelbauer, Karl; Golub, Todd R.
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

启动剂瞬时降低无细胞DNA的清除率以改善液体活检

Science
IF45.8
2024-01-010
OAAI
Carmen Martin-Alonso; Shervin Tabrizi; Kan Xiong; Timothy Blewett; Sainetra Sridhar; Andjela Crnjac; Sahil Patel; Zhenyi An; Ahmet Bekdemir; Douglas Shea; Shih‐Ting Wang; Sergio A. Rodriguez‐Aponte; Christopher A. Naranjo; Justin Rhoades; Jesse D. Kirkpatrick; Heather E. Fleming; Ava P. Amini; Todd R. Golub; John Christopher Love; Sangeeta N. Bhatia; Viktor A. Adalsteinsson
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
MOLECULAR CELL
IF16.6
2024-01-0115
OAAI
Hofman, Damon A.; Ruiz-Orera, Jorge; Yannuzzi, Ian; Murugesan, Rakesh; Brown, Adam; Clauser, Karl R.; Condurat, Alexandra L.; van Dinter, Jip T.; Engels, Sem A. G.; Goodale, Amy; van der Lugt, Jasper; Abid, Tanaz; Wang, Li; Zhou, Kevin N.; Vogelzang, Jayne; Ligon, Keith L.; Phoenix, Timothy N.; Roth, Jennifer A.; Root, David E.; Hubner, Norbert; Golub, Todd R.; Bandopadhayay, Pratiti; van Heesch, Sebastiaan; Prensner, John R.
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

PTPN2/PTPN1抑制剂ABBV-CLS-484释放有效的抗肿瘤免疫力

Nature
IF48.5
2023-10-040
OAAI
Christina K. Baumgartner; Hakimeh Ebrahimi-Nik; Arvin Iracheta-Vellve; Keith M. Hamel; Kira E. Olander; Thomas G. R. Davis; Kathleen A. McGuire; Geoff T. Halvorsen; Omar I. Avila; Chirag H. Patel; Sarah Y. Kim; Ashwin V. Kammula; Audrey J. Muscato; Kyle Halliwill; Prasanthi Geda; Kelly L. Klinge; Zhaoming Xiong; Ryan Duggan; Liang Mu; Mitchell D. Yeary; James C. Patti; Tyler M. Balon; Rebecca Mathew; Carey Backus; Domenick E. Kennedy; Angeline Chen; Kenton Longenecker; Joseph T. Klahn; Cara L. Hrusch; Navasona Krishnan; Charles W. Hutchins; Jax P. Dunning; Marinka Bulic; Payal Tiwari; Kayla J. Colvin; Cun Lan Chuong; Ian C. Kohnle; Matthew G. Rees; Andrew Boghossian; Melissa Ronan; Jennifer A. Roth; Meng-Ju Wu; Juliette S. M. T. Suermondt; Nelson H. Knudsen; Collins K. Cheruiyot; Debattama R. Sen; Gabriel K. Griffin; Todd R. Golub; Nabeel El-Bardeesy; Joshua H. Decker; Yi Yang; Magali Guffroy; Stacey Fossey; Patricia Trusk; Im-Meng Sun; Yue Liu; Wei Qiu; Qi Sun; Marcia N. Paddock; Elliot P. Farney; Mark A. Matulenko; Clay Beauregard; Jennifer M. Frost; Kathleen B. Yates; Philip R. Kym; Robert T. Manguso
Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030

TBCRC 030中三阴性乳腺癌新辅助化疗后循环肿瘤DNA与残余肿瘤负荷的关系

ANNALS OF ONCOLOGY
IF65.4
2023-10-0113
OAAI
Parsons, H. A.; Blewett, T.; Chu, X.; Sridhar, S.; Santos, K.; Xiong, K.; Abramson, V. G.; Patel, A.; Cheng, J.; Brufsky, A.; Rhoades, J.; Force, J.; Liu, R.; Traina, T. A.; Carey, L. A.; Rimawi, M. F.; Miller, K. D.; Stearns, V.; Specht, J.; Falkson, C.; Burstein, H. J.; Wolff, A. C.; Winer, E. P.; Tayob, N.; Krop, I. E.; Markrigiorgos, G. M.; Golub, T. R.; Mayer, E. L.; Adalsteinsson, V. A.
BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

BAF复杂扰动作为H3K27M小儿神经胶质瘤的新治疗机会

NEURO-ONCOLOGY
IF13.4
2023-06-120
OAAI
Panditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh; Hoffman, Samantha; Kugener, Guillaume; Shaw, McKenzie; Hack, Olivia; Dempster, Joshua; Lareau, Caleb; Quezada, Michael; Stanton, Ann-Catherine; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John; Root, David; Anastas, Jamie; Jones, Kristen; Conway, Amy; Stopka, Sylwia; Regan, Michael; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Mathewson, Nathan; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Nguyen, Quang-De; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity
NATURE GENETICS
IF31.8
2023-04-2724
OAAI
Bae, Jin H. H.; Liu, Ruolin; Roberts, Eugenia; Nguyen, Erica; Tabrizi, Shervin; Rhoades, Justin; Blewett, Timothy; Xiong, Kan; Gydush, Gregory; Shea, Douglas; An, Zhenyi; Patel, Sahil; Cheng, Ju; Sridhar, Sainetra; Liu, Mei Hong; Lassen, Emilie; Skytte, Anne-Bine; Gronska-Peski, Marta; Shoag, Jonathan E. E.; Evrony, Gilad D. D.; Parsons, Heather A. A.; Mayer, Erica L. L.; Makrigiorgos, G. Mike; Golub, Todd R. R.; Adalsteinsson, Viktor A. A.
ANJ810 is a highly selective novel MCL1 inhibitor with optimized in vivo clearance showing robust efficacy in preclinical solid and hematological tumor models
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Rauh, Ulrike; Wei, Guo; Serrano-Wu, Michael; Kosmidis, Georgios; Kaulfuss, Stefan; Siegel, Franziska; Thede, Kai; McFarland, James; Lemke, Christopher; Werbeck, Nicolas; Nowak-Reppel, Katrin; Pillari, Sabine; Menz, Stephan; Ocker, Matthias; Hubbard, Brian; Kaushik, Virendar; Ziegelbauer, Karl; Golub, Todd

研究方向

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