Andrew P. Hinck - Publications, H-index & Citations

Andrew P. Hinck

university of pittsburgh

41H指数

213论文数

5.7K被引数

收录论文 53

发表时间

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators 解析寄生虫TGFβ拮抗剂的作用机制启发细胞类型特异性TGFβ调节剂的创制

Advanced Science

IF14.1

2026-04-20

OAAI

Maarten van Dinther; Tristin Schwartze; Jiying Zhang; Kun Fan; Gerard van der Zon; Luke Power; Cynthia S. Hinck; Claire Ciancia; Ananya Mukundan; Roman Gonzalez-Prieto; Peter van Veelen; Rick M. Maizels; Andrew P. Hinck; Peter ten Dijke

Molecular Engineering of the Helminth TGF-β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF-β Signaling in Fibroblasts 蠕虫TGF-β模拟物TGM1和TGM4的分子工程改造揭示了成纤维细胞中TGF-β信号通路的一种新型拮抗剂

the faseb journal

IF0

2026-03-31

OAAI

Kyle T. Cunningham; Claire Ciancia; Tiffany Campion; Maarten van Dinther; Nadia Davis; Anja Duffy; Anna L. L. Heawood; Luke Power; Anna Sanders; Shashi P. Singh; Danielle J. Smyth; Elizabeth Thompson; Ruby White; Andrew P. Hinck; Peter ten Dijke; Rick M. Maizels

Improved protein binder design using β-pairing targeted RFdiffusion 利用β-配对靶向RFdiffusion改进蛋白质结合剂设计

Nature Communications

IF15.7

2026-01-10

OAAI

Isaac Sappington; Martin Toul; David S. Lee; Stephanie A. Robinson; Inna Goreshnik; Clara McCurdy; Tung Ching Chan; Nic Buchholz; Buwei Huang; Dionne Vafeados; Mariana Garcia-Sanchez; Nicole Roullier; Matthias Glögl; Christopher J. Kim; Joseph L. Watson; Susana Vázquez Torres; Koen H. G. Verschueren; Kenneth Verstraete; Cynthia S. Hinck; Melisa Benard-Valle; Brian Coventry; Jeremiah Nelson Sims; Green Ahn; Xinru Wang; Andrew P. Hinck; Timothy P. Jenkins; Hannele Ruohola-Baker; Steven M. Banik; Savvas N. Savvides; David Baker

Structural and functional analysis of the TGF-β mimic, TGM-2: an immunomodulatory helminth protein TGF-β模拟物TGM-2的结构与功能分析：一种免疫调节性蠕虫蛋白

Genes & Immunity

IF0

2025-12-18

OAAI

Emmaculate Yaah Ntang; Kyle T. Cunningham; Shashi P. Singh; Claire Ciancia; Anna Sanders; Sergio Lilla; Ananya Mukundan; Stephen M. Ghogomu; Andrew P. Hinck; Rick M. Maizels

Th1 differentiation and function are inhibited in neonates following human metapneumovirus infection Th1分化及功能在新生儿中于人呼吸道合胞病毒感染后受到抑制

JOURNAL OF IMMUNOLOGY

IF3.4

2025-04-25

OAAI

Brown, Emma; Lan, Jie; Parks, Olivia B.; Hinck, Cynthia S.; Hinck, Andrew P.; Williams, John, V; Eddens, Taylor

Molecular Basis of Interchain Disulfide Bond Formation in BMP-9 and BMP-10 BMP-9和BMP-10中链间二硫键形成的分子基础

JOURNAL OF MOLECULAR BIOLOGY

IF4.5

2025-02-01

OAAI

Schwartze, Tristin A.; Morosky, Stefanie A.; Rosato, Teresa L.; Henrickson, Amy; Lin, Guowu; Hinck, Cynthia S.; Taylor, Alexander B.; Olsen, Shaun K.; Calero, Guillermo; Demeler, Borries; Roman, Beth L.; Hinck, Andrew P.

The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding

EMBO REPORTS

IF6.2

2024-11-28

PREAI

Singh, Shashi P.; Smyth, Danielle J.; Cunningham, Kyle T.; Mukundan, Ananya; Byeon, Chang-Hyeock; Hinck, Cynthia S.; White, Madeleine P. J.; Ciancia, Claire; Wasowska, Natalia; Sanders, Anna; Jin, Regina; White, Ruby F.; Lilla, Sergio; Zanivan, Sara; Schoenherr, Christina; Inman, Gareth J.; van Dinther, Maarten; ten Dijke, Peter; Hinck, Andrew P.; Maizels, Rick M.

Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway

LIFE SCIENCES

IF5.1

2024-11-01

OAAI

Zheng, Guixi; Wu, Lianqiu; Bouamar, Hakim; Cserhati, Matyas; Chiu, Yu-Chiao; Hinck, Cinthia S.; Wieteska, Lukasz; Torrez, Carla R. Zeballos; Hu, Ruolei; Easley, Acarizia; Chen, Yidong; Hinck, Andrew P.; Cigarroa, Francisco G.; Sun, Lu-Zhe

Betaglycan sustains HGF/Met signaling in lung cancer and endothelial cells promoting cell migration and tumor growth Betaglycan在肺癌和内皮细胞中维持HGF/Met信号传导，促进细胞迁移和肿瘤生长

HELIYON

IF3.6

2024-05-01

OAAI

Cervantes-Villagrana, Rodolfo Daniel; Mendoza, Valentin; Hinck, Cynthia S.; de la Fuente-Leon, Rosa Luz; Hinck, Andrew P.; Reyes-Cruz, Guadalupe; Vazquez-Prado, Jose; Lopez-Casillas, Fernando

Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells

CELLS

IF5.2

2024-02-05

OAAI

Cheng, Ya-Wen; Anzell, Anthony R.; Morosky, Stefanie A.; Schwartze, Tristin A.; Hinck, Cynthia S.; Hinck, Andrew P.; Roman, Beth L.; Davidson, Lance A.

CD44 acts as a coreceptor for cell- specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-17

OAAI

van Dinther, Maarten; Cunningham, Kyle T.; Singh, Shashi Prakash; White, Madeleine P. J.; Campion, Tiffany; Ciancia, Claire; van Veelen, Peter A.; de Ru, Arnoud H.; Gonzalez-Prieto, Roman; Mukundan, Ananya; Byeon, Chang- Hyeock; Staggers, Sophia R.; Hinck, Cynthia S.; Hinck, Andrew P.; ten Dijke, Peter; Maizels, Rick M.

An oncolytic virus-delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2023-08-08

OAAI

Depeaux, Kristin; Rivadeneira, Dayana B.; Lontos, Konstantinos; Dean, Victoria G.; Gunn, William G.; Watson, McLane J.; Yao, Tianhong; Wilfahrt, Drew; Hinck, Cynthia; Wieteska, Lukasz; Thorne, Stephen H.; Hinck, Andrew P.; Delgoffe, Greg M.

Computational modeling of TGF-?2:T?RI:T?RII receptor complex assembly as mediated by the TGF-? coreceptor betaglycan

BIOPHYSICAL JOURNAL

IF3.1

2023-04-01

OAAI

Madamanchi, Aasakiran; Ingle, Michelle; Hinck, Andrew P.; Umulis, David M.

TGFβ carrying exosomes in plasma: potential biomarkers of cancer progression in patients with head and neck squamous cell carcinoma 血浆中携带tgf β 的外泌体: 头颈部鳞状细胞癌患者癌症进展的潜在生物标志物

BRITISH JOURNAL OF CANCER

IF6.8

2023-02-21

OAAI

Ludwig, Nils; Yerneni, Saigopalakrishna S.; Harasymczuk, Malgorzata; Szczepanski, Miroslaw J.; Gluszko, Alicja; Kukwa, Wojciech; Jordan, Theresa; Spanier, Gerrit; Taxis, Juergen; Spoerl, Steffen; Meier, Johannes K.; Hinck, Cynthia S.; Campbell, Phil G.; Reichert, Torsten E.; Hinck, Andrew P.; Whiteside, Theresa L.

TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro-angiogenic phenotype 来自头颈部鳞状细胞癌细胞的tgf β 小细胞外囊泡将巨噬细胞重新编程为促血管生成表型

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2022-12-20

OAAI

Ludwig, Nils; Yerneni, Saigopalakrishna S.; Azambuja, Juliana H.; Pietrowska, Monika; Widlak, Piotr; Hinck, Cynthia S.; Gluszko, Alicja; Szczepanski, Miroslaw J.; Karmer, Teresa; Kallinger, Isabella; Schulz, Daniela; Bauer, Richard J.; Spanier, Gerrit; Spoerl, Steffen; Meier, Johannes K.; Ettl, Tobias; Razzo, Beatrice M.; Reichert, Torsten E.; Hinck, Andrew P.; Whiteside, Theresa L.

On 'Deuterium exchange of poly-dl-alanine in aqueous solution' by Arieh Berger and K. Linderstrom-Lang

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2022-09-01

PREAI

Hinck, Andrew P.

Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-06-01

OAAI

Mukundan, Ananya; Byeon, Chang-Hyeock; Hinck, Cynthia S.; Cunningham, Kyle; Campion, Tiffany; Smyth, Danielle J.; Maizels, Rick M.; Hinck, Andrew P.

TGFBR3L is an inhibin B co-receptor that regulates female fertility

SCIENCE ADVANCES

IF12.5

2021-12-17

OAAI

Brule, Emilie; Wang, Ying; Li, Yining; Lin, Yeu-Farn; Zhou, Xiang; Ongaro, Luisina; Alonso, Carlos A., I; Buddle, Evan R. S.; Schneyer, Alan L.; Byeon, Chang-Hyeock; Hinck, Cynthia S.; Mendelev, Natalia; Russell, John P.; Cowan, Mitra; Boehm, Ulrich; Ruf-Zamojski, Frederique; Zamojski, Michel; Andoniadou, Cynthia L.; Sealfon, Stuart C.; Harrison, Craig A.; Walton, Kelly L.; Hinck, Andrew P.; Bernard, Daniel J.

RESISTANCE TO ONCOLYTIC VACCINIA CAN BE REVERSED BY TARGETING REGULATORY T CELLS WITH VACCINIA-DIRECTED DELIVERY OF A TGFβ INHIBITOR

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

DePeaux, Kristin; Rivadeneira, Dayana; Watson, McLane; Hinck, Andrew; Thorne, Stephen; Delgoffe, Greg

Novel TGFβ Inhibitors Ameliorate Oral Squamous Cell Carcinoma Progression and Improve the Antitumor Immune Response of Anti-PD-L1 Immunotherapy

MOLECULAR CANCER THERAPEUTICS

IF5.5

2021-04-13

OAAI

Ludwig, Nils; Wieteska, Lukasz; Hinck, Cynthia S.; Yerneni, Saigopalakrishna S.; Azambuja, Juliana H.; Bauer, Richard J.; Reichert, Torsten E.; Hinck, Andrew P.; Whiteside, Theresa L.

研究方向