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J

Jan Steyaert

vrije universiteit brussel

69H指数
586论文数
2.4W被引数
收录论文 149
发表时间
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Molecular arrangement and modulation of extrasynaptic αβδ GABAA receptors突触外αβδ GABAA受体的分子排列与调节
errNature Communications
IF15.7
err2026-08-18
err0
errOAAI
errStephanie A. Nestorow; Wan-Na Chen; Daniel Bertrand; Ayla A. Wahid; Caroline E. Wyatt; Martin Mortensen; Thomas Clairfeuille; Michael Reutlinger; Gregoire Friz; Els Pardon; Jan Steyaert; Graham Ladds; Giuseppe Cecere; Trevor G. Smart; Maria-Clemencia Hernandez; Lisa Joedicke; Paul S. Miller
err分享
err收藏
Structural basis for activation and potentiation in a human α5β3 GABAA receptor人α5β3 GABAA受体激活和增强的分子结构基础
errNature Communications
IF15.7
err2026-06-15
err0
errOAAI
errJohn Cowgill; Chen Fan; Jan Steyaert; Rebecca J. Howard; Erik Lindahl
err分享
err收藏
Structural and functional characterisation of the Crimean-Congo haemorrhagic fever virus RNA dependent RNA polymerase克里米亚-刚果出血热病毒RNA依赖性RNA聚合酶的结构与功能表征
errNature Communications
IF15.7
err2026-06-09
err0
errOAAI
errAdrian Deng; Rory Cunnison; Loïc Carrique; Franziska Günl; Els Pardon; Jan Steyaert; David Nguyen Duc; Jonathan M. Grimes; Nicole Robb; Jeremy R. Keown
err分享
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Nanobody-mediated control of long RSH Rel and RelA catalysis by restriction of their conformational landscape纳米抗体介导的长RSH Rel和RelA催化作用通过限制其构象景观进行控制
errNature Communications
IF15.7
err2026-05-13
err0
errOAAI
errKatleen Van Nerom; Andres Ainelo; Kyo Coppieters ‘t Wallant; Ariel Talavera-Perez; Dannele Echemendia-Blanco; Sarah Peeters; Brahim El Khalfaoui Oulali; Hedvig Tamman; Tatsuaki Kurata; Mohammad Roghanian; Chloé Martens; Els Pardon; Jan Steyaert; Vasili Hauryliuk; Abel Garcia-Pino
err分享
err收藏
Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development结构独特的Teneurin复合物调控早期皮质发育中的不同程序
errNature Communications
IF15.7
err2026-04-16
err0
errOAAI
errMiguel Berbeira-Santana; Claudia Peregrina; Kosuke Okuda; Jin Chuan Zhou; Maria Carrasquero-Ordaz; Amy V. Roberts; Anne E. Thomas; Evert Haanappel; Matthieu Chavent; Kamel el Omari; Lindsay A. Baker; Daniel T. Pederick; Els Pardon; Jan Steyaert; U. Valentin Nägerl; Daniel del Toro; Elena Seiradake
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A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardiaβ1AR的正性别构调节剂，具有儿茶酚胺敏感性多形性室性心动过速的拮抗活性
errJournal of Clinical Investigation
IF13.6
err2025-12-15
err0
errOAAI
errGrogan, Alyssa; Perelli, Robin M.; Ahn, Seungkirl; Jiang, Haoran; Jyothidasan, Arun; Sood, Damini; You, Chongzhao; Israel, David I.; Shaginian, Alex; Chen, Qiuxia; Liu, Jian; Wang, Jialu; Steyaert, Jan; Kahsai, Alem W.; Landstrom, Andrew P.; Lefkowitz, Robert J.; Rockman, Howard A.
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Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP铜绿假单胞菌透性酶LysP介导特异性赖氨酸转运的结构基础
errNature Communications
IF15.7
err2025-12-04
err0
errOAAI
errDeniz Bicer; Rei Matsuoka; Aurélien F. A. Moumbock; Preethi Sukumar; Albert Suades; Harish Cheruvara; Andrew Quigley; David Drew; Els Pardon; Jan Steyaert; Peter J. F. Henderson; Martin Caffrey; Julia J. Griese; Emmanuel Nji
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Correction: A nanobody-based microfluidic chip for fast and automated purification of protein complexes更正：一种基于纳米抗体的微流控芯片，用于蛋白质复合物的快速和自动化纯化
errlab on a chip
IF0
err2025-09-20
err0
errOAAI
errPhebe De Keyser; Mitch de Waard; Ignaas S. M. Jimidar; Sandrien Verloy; Steven Janvier; Valentina Kalichuk; Thomas Zögg; Alexandre Wohlkönig; Els Pardon; Jan Steyaert; Gert Desmet
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Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetamsSV2A蛋白的结构揭示了破伤风神经毒素和抗癫痫螺环类化合物的结合模式
errNATURE COMMUNICATIONS
IF15.7
err2025-05-05
err0
errOAAI
errSchenck, Stephan; Laeremans, Toon; Steyaert, Jan; Brunner, Janine D.
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err收藏
Molecular basis of pyruvate transport and inhibition of the human mitochondrial pyruvate carrier丙酮酸转运和人类线粒体丙酮酸载体抑制的分子基础
errSCIENCE ADVANCES
IF12.5
err2025-04-18
err1
errOAAI
errSichrovsky, Maximilian; Lacabanne, Denis; Ruprecht, Jonathan J.; Rana, Jessica J.; Stanik, Klaudia; Dionysopoulou, Mariangela; Sowton, Alice P.; King, Martin S.; Jones, Scott A.; Cooper, Lee; Hardwick, Steven W.; Paris, Giulia; Chirgadze, Dimitri Y.; Ding, Shujing; Fearnley, Ian M.; Palmer, Shane M.; Pardon, Els; Steyaert, Jan; Forrest, Lucy R.; Tavoulari, Sotiria; Kunji, Edmund R. S.
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A biosensor-based phage display selection method for automated, high-throughput Nanobody discovery一种基于生物传感器的噬菌体展示选择方法，用于自动，高通量的纳米抗体发现
errBIOSENSORS & BIOELECTRONICS
IF10.5
err2025-03-01
err0
PREAI
errDe Keyser, Phebe; Kalichuk, Valentina; Zogg, Thomas; Wohlkonig, Alexandre; Schenck, Stephan; Brunner, Janine; Pardon, Els; Steyaert, Jan
err分享
err收藏
Allosteric modulation of protein-protein interactions in signal transduction with Nanobodies
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2025-03-01
err0
PREAI
errPardon, Els; Wohlkoenig, Alex; Steyaert, Jan
err分享
err收藏
Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector
errPATHOGENS
IF3.3
err2025-02-02
err0
errOAAI
errZhang, Jingjing; Wang, Mengfei; Wang, Dan; Zhang, Xiangyi; Ma, Yue; Pardon, Els; Steyaert, Jan; Abskharon, Romany; Wang, Fei; Ma, Jiyan
err分享
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The conserved lysine residue in transmembrane helix 5 is pivotal for the cytoplasmic gating of the L-amino acid transporters
errPNAS NEXUS
IF3.8
err2025-01-02
err0
errOAAI
errFort, Joana; Nicolas-Arago, Adria; Maggi, Luca; Martinez-Molledo, Maria; Kapiki, Despoina; Gonzalez-Novoa, Paula; Gomez-Gejo, Patricia; Zijlstra, Niels; Bodoy, Susanna; Pardon, Els; Steyaert, Jan; Llorca, Oscar; Orozco, Modesto; Cordes, Thorben; Palacin, Manuel
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Functional modulation of RAGE activation by multimeric S100B using single-domain antibodies
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-12-01
err0
errOAAI
errSimoes, Margarida C.; Cristovao, Joana S.; Pardon, Els; Steyaert, Jan; Fritz, Guenter; Gomes, Claudio M.
err分享
err收藏
Structural basis of antimicrobial membrane coat assembly by human GBP1
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-10-11
err0
errOAAI
errKuhm, Tanja; Taisne, Clemence; Pinto, Cecilia de Agrela; Gross, Luca; Giannopoulou, Evdokia A.; Huber, Stefan T.; Pardon, Els; Steyaert, Jan; Tans, Sander J.; Jakobi, Arjen J.
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Structural basis of μ-opioid receptor targeting by a nanobody antagonist
errNATURE COMMUNICATIONS
IF15.7
err2024-10-09
err0
errOAAI
errYu, Jun; Kumar, Amit; Zhang, Xuefeng; Martin, Charlotte; Van Holsbeeck, Kevin; Raia, Pierre; Koehl, Antoine; Laeremans, Toon; Steyaert, Jan; Manglik, Aashish; Ballet, Steven; Boland, Andreas; Stoeber, Miriam
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Structural basis of thiamine transport and drug recognition by SLC19A3SLC19A3对硫胺素转运和药物识别的结构基础
errNATURE COMMUNICATIONS
IF15.7
err2024-10-02
err0
errOAAI
errGabriel, Florian; Spriestersbach, Lea; Fuhrmann, Antonia; Jungnickel, Katharina E. J.; Mostafavi, Siavash; Pardon, Els; Steyaert, Jan; Loew, Christian
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err收藏
Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-10-01
err1
errOAAI
errLi, Chenyao; Willegems, Katrien; Uchanski, Tomasz; Pardon, Els; Steyaert, Jan; Efremov, Rouslan G.
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err收藏
Design and Implementation of a Proof-of-Concept Robotic-Microfluidic Interface to Bridge Spatial Comprehensive Three-Dimensional Liquid Chromatography with Mass Spectrometry
errANALYTICAL CHEMISTRY
IF6.7
err2024-09-26
err0
PREAI
errAmini, Ali; Themelis, Thomas; Janvier, Steven; Steyaert, Jan; De Vos, Jelle; Eeltink, Sebastiaan
err分享
err收藏

研究方向

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合作学者
合作期刊
R
Robert J. Lefkowitz
H 指数: 213 · 论文数: 858
J
Joseph Schlessinger
H 指数: 174 · 论文数: 719
R
Robert G. Parton
H 指数: 149 · 论文数: 705
B
Brian K. Kobilka
H 指数: 140 · 论文数: 520
D
David Eisenberg
H 指数: 139 · 论文数: 744
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