Friedrich W. Herberg - Publications, H-index & Citations

Friedrich W. Herberg

university of kassel

50H指数

242论文数

7.2K被引数

收录论文 98

发表时间

Aortic disease-linked mutations reveal unexpected convergent allosteric mechanisms of protein kinase G misregulation 主动脉疾病相关突变揭示了蛋白激酶G失调的意外趋同别构机制

Science Advances

IF12.5

2026-09-02

OAAI

Karla Martinez Pomier; Leopold Jahn; Bryan VanSchouwen; Hebatallah Mohamed; Madoka Akimoto; Sun Woo Jung; Daniela Bertinetti; Johannes Mehringer; Leonardo Della Libera; Friederike Cuello; Friedrich W. Herberg; Giuseppe Melacini

A small molecule reduces both parkinsonism and l-dopa–induced dyskinesia in animal models of Parkinson’s disease 一种小分子在帕金森病动物模型中同时降低帕金森症状和左旋多巴诱导的运动障碍

Science Translational Medicine

IF14.6

2026-07-15

PREAI

Aarash Bordbar; Bernard Bloem; Colton Lloyd; Tom H. Johnston; Jay S. Schneider; Erwan Bezard; Elsa Pioli; Qin Li; Caesar Tawfeeq; Nathan Vu Pham; Gary Huber; Jian Wu; Michael P. Hill; Jonathan M. Brotchie; J. Andrew McCammon; Friedrich W. Herberg; Susan Taylor; David M. Weiner; Kalpana Merchant; Iman Famili

Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway Hedgehog通路中非典型GPCR信号传导的结构机制

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-04-01

PREAI

Steiner, William P.; Iverson, Nathan; Liu, Guibing; Venkatakrishnan, Varun; Wu, Jian; Stepniewski, Tomasz Maciej; Michaelson, Zachary; Brockel, Jan W.; Zhu, Ju-Fen; Bruystens, Jessica G. H.; Lee, Annabel; Nelson, Isaac; Bertinetti, Daniela; Arveseth, Corvin D.; Tan, Gerald; Spaltenstein, Paul; Xu, Jiewei; Huttenhain, Ruth; Kay, Michael S.; Herberg, Friedrich W.; Cao, Erhu; Selent, Jana; Anand, Ganesh S.; Dunbrack Jr, Roland L.; Taylor, Susan S.; Myers, Benjamin R.

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation 蛋白激酶A调节亚基Iβ变体的功能分化：N3A基序在PKA调控中的重要性

FEBS JOURNAL

IF4.2

2025-12-01

OAAI

Wallbott, Maximilian; Weng, Jui-Hung; Pane, Valeria; Ma, Yuliang; Wu, Jian; Taylor, Susan S.; Herberg, Friedrich W.

Autophosphorylation of conserved yeast and human casein kinase 1 isozymes regulates Elongator-dependent tRNA modifications 保守酵母和人类酪蛋白激酶1同工酶的自身磷酸化调节Elongator依赖性的tRNA修饰

NUCLEIC ACIDS RESEARCH

IF13.1

2025-09-23

OAAI

Landrock, Maria Friederike; Krutyholowa, Roscislaw; Bohnert, Pauline; Mazur, Jaroslaw; Honc, Malgorzata; Hammermeister, Alexander; Bessler, Larissa; Scherf, David; Elms, Anna; Radczuk, Natalia; Skupien-Rabian, Bozena; Jankowska, Urszula; Herberg, Friedrich W.; Helm, Mark; Klassen, Roland; Glatt, Sebastian; Schaffrath, Raffael

Non-covalent and covalent binding of proteins on ultrananocrystalline diamond films with different surface terminations 蛋白质在具有不同表面终止基团的超纳米晶体金刚石薄膜上的非共价键和共价键结合

DIAMOND AND RELATED MATERIALS

IF5.1

2025-06-01

PREAI

Ghasemitabesh, Rezvaneh; Merker, Daniel; Broeckel, Jan W.; Bertinetti, Daniela; Zakaria, Yahya; Welle, Alexander; Herberg, Friedrich W.; Popov, Cyril

Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA, a neurodegenerative disease in which the PRKAR1B L50R variant is expressed NLPD-PKA患者中蛋白激酶A的别构调控，NLPD-PKA是一种神经退行性疾病，在该疾病中表达PRKAR1B L50R变异体

FEBS JOURNAL

IF4.2

2025-04-17

PREAI

Tal Benjamin-Zukerman; Valeria Pane; Rania Safadi-Safa; Meir Solomon; Varda Lev-Ram; Mohammad Aboraya; Anwar Dakwar; Daniela Bertinetti; Andrew Hoy; Merel O. Mol; John van Swieten; Rodrigo Maillard; Friedrich W. Herberg; Ronit Ilouz

LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains (vol 20, e3001427, 2022)LRRK2动力学分析确定了其催化结构域间串扰的别构调控（vol 20, e3001427, 2022）

PLOS BIOLOGY

IF7.2

2025-02-03

OAAI

Weng, Jui-Hung; Aoto, Phillip C.; Lorenz, Robin; Wu, Jian; Schmidt, Sven H.; Manschwetus, Jascha T.; Kaila-Sharma, Pallavi; Silletti, Steve; Torres-Paris, Constanza; Mathea, Sebastian; Chatterjee, Deep; Knapp, Stefan; Herberg, Friedrich W.; Taylor, Susan S.

RedOx regulation of LRRK2 kinase activity by active site cysteines

NPJ PARKINSONS DISEASE

IF8.2

2024-04-03

OAAI

Trilling, Chiara R.; Weng, Jui-Hung; Sharma, Pallavi Kaila; Nolte, Viktoria; Wu, Jian; Ma, Wen; Boassa, Daniela; Taylor, Susan S.; Herberg, Friedrich W.

Role of the leucine-rich repeat protein kinase 2 C-terminal tail in domain cross-talk

BIOCHEMICAL JOURNAL

IF4.3

2024-02-19

OAAI

Sharma, Pallavi Kaila; Weng, Jui-Hung; Manschwetus, Jascha T.; Wu, Jian; Ma, Wen; Herberg, Friedrich W.; Taylor, Susan S.

Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW

BIOCHEMICAL JOURNAL

IF4.3

2023-06-12

OAAI

Stoermer, Eliza; Weng, Jui-Hung; Wu, Jian; Bertinetti, Daniela; Sharma, Pallavi Kaila; Ma, Wen; Herberg, Friedrich W.; Taylor, Susan S.

Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Chiorini, JA; Zimmermann, B; Yang, L; Smith, RH; Ahearn, A; Herberg, F; Kotin, RM

Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A Edmond Fischer的激酶遗产: 蛋白激酶抑制剂和蛋白激酶A的历史

IUBMB LIFE

IF3.2

2023-02-28

OAAI

Taylor, Susan S.; Herberg, Friedrich W.; Veglia, Gianluigi; Wu, Jian

Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage

CIRCULATION

IF38.6

2022-12-06

OAAI

Ercu, Maria; Muecke, Michael B.; Pallien, Tamara; Marko, Lajos; Sholokh, Anastasiia; Schaechterle, Carolin; Aydin, Atakan; Kidd, Alexa; Walter, Stephan; Esmati, Yasmin; McMurray, Brandon J.; Lato, Daniella F.; Yumi Sunaga-Franze, Daniele; Dierks, Philip H.; Flores, Barbara Isabel Montesinos; Walker-Gray, Ryan; Gong, Maolian; Merticariu, Claudia; Zuehlke, Kerstin; Russwurm, Michael; Liu, Tiannan; Batolomaeus, Theda U. P.; Pautz, Sabine; Schelenz, Stefanie; Taube, Martin; Napieczynska, Hanna; Heuser, Arnd; Eichhorst, Jenny; Lehmann, Martin; Miller, Duncan C.; Diecke, Sebastian; Qadri, Fatimunnisa; Popova, Elena; Langanki, Reika; Movsesian, Matthew A.; Herberg, Friedrich W.; Forslund, Sofia K.; Mueller, Dominik N.; Borodina, Tatiana; Maass, Philipp G.; Baehring, Sylvia; Huebner, Norbert; Bader, Michael; Klussmann, Enno

Investigating the molecular disease mechanisms of the human p.G592R PRKD1 mutation in human induced pluripotent stem cell-derived cardiomyocytes

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2022-12-01

PREAI

Orth, Julia; Witthoff, Fabian; Raabe, Janice; Stathopoulou, Konstantina; Pietsch, Niels; Carrier, Lucie; Henning, Philipp; Herberg, Friedrich W.; Cuello, Friederike

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-10-06

OAAI

Happ, John T.; Arveseth, Corvin D.; Bruystens, Jessica; Bertinetti, Daniela; Nelson, Isaac B.; Olivieri, Cristina; Zhang, Jingyi; Hedeen, Danielle S.; Zhu, Ju-Fen; Capener, Jacob L.; Brockel, Jan W.; Vu, Lily; King, C. C.; Ruiz-Perez, Victor L.; Ge, Xuecai; Veglia, Gianluigi; Herberg, Friedrich W.; Taylor, Susan S.; Myers, Benjamin R.

An auto-inhibited state of protein kinase G and implications for selective activation 蛋白激酶G的自动抑制状态及其对选择性激活的影响

ELIFE

IF0

2022-08-05

OAAI

Sharma, Rajesh; Kim, Jeong Joo; Qin, Liying; Henning, Philipp; Akimoto, Madoka; VanSchouwen, Bryan; Kaur, Gundeep; Sankaran, Banumathi; MacKenzie, Kevin R.; Melacini, Giuseppe; Casteel, Darren E.; Herberg, Friedrich W.; Kim, Choel

The Forgotten PKAs: New Insights Revealed by the First Crystal Structure of a PKA C Beta Splice Variant, Cβ4ab

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Bruystens, Jessica H.; Wu, Jian; Wallbott, Maximilian; Bertinetti, Daniela; Herberg, Friedrich W.; Taylor, Susan S.

The Tails of Protein Kinase A

MOLECULAR PHARMACOLOGY

IF3

2022-04-01

OAAI

Taylor, Susan S.; Soberg, Kristoffer; Kobori, Evan; Wu, Jian; Pautz, Sabine; Herberg, Friedrich W.; Skalhegg, Bjorn Steen

Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2 纳米抗体作为帕金森病相关LRRK2的变构调节剂

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-02-25

OAAI

Singh, Ranjan K.; Soliman, Ahmed; Guaitoli, Giambattista; Stoermer, Eliza; von Zweydorf, Felix; Dal Maso, Thomas; Oun, Asmaa; Van Rillaer, Laura; Schmidt, Sven H.; Chatterjee, Deep; David, Joshua A.; Pardon, Els; Schwartz, Thomas U.; Knapp, Stefan; Kennedy, Eileen J.; Steyaert, Jan; Herberg, Friedrich W.; Kortholt, Arjan; Gloeckner, Christian Johannes; Versees, Wim

研究方向