Michael Costanzo - Publications, H-index & Citations

Michael Costanzo

University of Bonn

54H指数

155论文数

1.4W被引数

收录论文 71

发表时间

Towards the construction of a virtual yeast 构建虚拟酵母

Nature

IF48.5

2026-07-01

PREAI

Liujia Qian; Zizhuo Zhou; Peijie Zhou; Zhen Dong; Xudong Zhang; Zhenwu Dai; Zhangyang Gao; Siqi Sun; Kevin R. Roy; Shuaiyao Wang; Nicola Zamboni; Charles Boone; Michael Costanzo; Jianzhe Li; Gianni Liti; Jia-Xing Yue; Markus Ralser; Evan Williams; Mattia Zampieri; Heng Jiang; Tailin Wu; Yalin Wang; Feiran Li; Joseph Schacherer; Rui Sun; Zhaoxing Li; Yaming Deng; Yi Chen; Zhiping Xie; Huiqiang Lou; Xiaowen Wang; Linhai Xie; Han Wen; Liangyi Chen; Kai Lei; George Rosenberger; Xue Cai; Yingrui Wang; Qi Xiao; Huaizong Shen; Gaowen Liu; Lei Ma; Brenda Andrews; Hui Lu; Kiryl Piatkevich; Yi Zhu; Lei Bai; Yizhi Cai; Yuping Chen; Weinan E; Ge Gao; Fuchu He; Luonan Chen; Stan Z. Li; Hongwu Ma; Liang Qiao; Lars M. Steinmetz; Leihan Tang; Tang Tang; Xiaofan Zhang; Jing Yang; Yifan Yang; Kaicheng Yu; Jianyang Zeng; Yefeng Zheng; Bowen Zhou; Tiannan Guo

Orobas: A computational approach for scoring and analysis of quantitative chemical-genetic interactions from CRISPR-Cas9 screens Orobas：一种用于对来自CRISPR-Cas9筛选的定量化学生物学相互作用进行评分和分析的计算方法

STAR Protocols

IF1.3

2026-05-01

PREAI

Hassan, Arshia Z.; Zhang, Xiang; Ward, Henry N.; Billmann, Maximilian; Bajjali, Salem; Brown, Kevin R.; Bhojoo, Urvi; Chan, Katherine; Lin, Kevin; Costanzo, Michael; Andrews, Brenda; Boone, Charles; Moffat, Jason; Myers, Chad L.

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles 人类细胞的全球遗传互作网络绘制了保守原则并指导基因共必需性谱的功能解释

Cell

IF42.5

2026-04-27

PREAI

Maximilian Billmann; Michael Costanzo; Xiang Zhang; Arshia Z. Hassan; Mahfuzur Rahman; Kevin R. Brown; Katherine S. Chan; Amy Hin Yan Tong; Carles Pons; Henry N. Ward; Catherine Ross; Jolanda van Leeuwen; Michael Aregger; Keith A. Lawson; Barbara Mair; Amy F. Roth; Nesli E. Sen; Duncan T. Forster; Guihong Tan; Patricia Mero

LLP1 is a pyrophosphatase involved in homeostasis/quality control of dolichol-linked oligosaccharide LLP1是一种焦磷酸酶，参与 dolichol-连接寡糖的稳态/质量控制。

JOURNAL OF CELL BIOLOGY

IF6.4

2025-09-29

PREAI

Li, Sheng-Tao; Kamada, Katsuhiko; Honda, Akinobu; Seino, Junichi; Matsuda, Tsugiyo; Suzuki, Takehiro; Dohmae, Naoshi; Shichino, Yuichi; Iwasaki, Shintaro; Noda, Yoichi; Costanzo, Michael; Boone, Charles; Suzuki, Tadashi

A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds

SCIENTIFIC REPORTS

IF3.9

2024-01-30

OAAI

Lin, Kevin; Chang, Ya-Chu; Billmann, Maximilian; Ward, Henry N.; Le, Khoi; Hassan, Arshia Z.; Bhojoo, Urvi; Chan, Katherine; Costanzo, Michael; Moffat, Jason; Boone, Charles; Bielinsky, Anja-Katrin; Myers, Chad L.

N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

NATURE COMMUNICATIONS

IF15.7

2023-10-27

OAAI

Varland, Sylvia; Silva, Rui Duarte; Kjosas, Ine; Faustino, Alexandra; Bogaert, Annelies; Billmann, Maximilian; Boukhatmi, Hadi; Kellen, Barbara; Costanzo, Michael; Drazic, Adrian; Osberg, Camilla; Chan, Katherine; Zhang, Xiang; Tong, Amy Hin Yan; Andreazza, Simonetta; Lee, Juliette J.; Nedyalkova, Lyudmila; Usaj, Matej; Whitworth, Alexander J.; Andrews, Brenda J.; Moffat, Jason; Myers, Chad L.; Gevaert, Kris; Boone, Charles; Martinho, Rui Goncalo; Arnesen, Thomas

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2023-09-01

OAAI

Mishra, Prashant K.; Au, Wei-Chun; Castineira, Pedro G.; Ali, Nazrin; Stanton, John; Boeckmann, Lars; Takahashi, Yoshimitsu; Costanzo, Michael; Boone, Charles; Bloom, Kerry S.; Thorpe, Peter H.; Basrai, Munira A.

Reproducibility metrics for context-specific CRISPR screens

CELL SYSTEMS

IF7.7

2023-05-01

OAAI

Billmann, Maximilian; Ward, Henry N.; Aregger, Michael; Costanzo, Michael; Andrews, Brenda J.; Boone, Charles; Moffat, Jason; Myers, Chad L.

G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Costanzo, M; Schub, O; Andrews, B

Repression of essential cell cycle genes increases cellular fitness

PLOS GENETICS

IF3.7

2022-08-29

OAAI

Conti, Michelle M.; Ghizzoni, Julie M.; Gil-Bona, Ana; Wang, Wen; Costanzo, Michael; Li, Rui; Flynn, Mackenzie J.; Zhu, Lihua Julie; Myers, Chad L.; Boone, Charles; Andrews, Brenda J.; Benanti, Jennifer A.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

JOURNAL OF CELL BIOLOGY

IF6.4

2021-11-05

OAAI

Nsamba, Emmanuel T.; Bera, Abesh; Costanzo, Michael; Boone, Charles; Gupta, Mohan L., Jr.

Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase

MOLECULAR CELL

IF16.6

2021-06-01

OAAI

Kong, Ka-Yiu Edwin; Fischer, Bernd; Meurer, Matthias; Kats, Ilia; Li, Zhaoyan; Ruehle, Frank; Barry, Joseph D.; Kirrmaier, Daniel; Chevyreva, Veronika; San Luis, Bryan-Joseph; Costanzo, Michael; Huber, Wolfgang; Andrews, Brenda J.; Boone, Charles; Knop, Michael; Khmelinskii, Anton

A method for benchmarking genetic screens reveals a predominant mitochondrial bias 一种对遗传筛选进行基准测试的方法揭示了主要的线粒体偏见

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2021-05-20

OAAI

Rahman, Mahfuzur; Billmann, Maximilian; Costanzo, Michael; Aregger, Michael; Tong, Amy H. Y.; Chan, Katherine; Ward, Henry N.; Brown, Kevin R.; Andrews, Brenda J.; Boone, Charles; Moffat, Jason; Myers, Chad L.

Reduced gene dosage of histone H4 prevents CENP-A mislocalization and chromosomal instability in Saccharomyces cerevisiae 降低组蛋白H4的基因剂量可防止酿酒酵母中的cenp-a错误定位和染色体不稳定性

GENETICS

IF5.1

2021-03-05

OAAI

Eisenstatt, Jessica R.; Ohkuni, Kentaro; Au, Wei-Chun; Preston, Olivia; Gliford, Loran; Suva, Evelyn; Costanzo, Michael; Boone, Charles; Basrai, Munira A.

τ-SGA: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast

NATURE PROTOCOLS

IF16

2021-01-18

OAAI

Kuzmin, Elena; Rahman, Mahfuzur; VanderSluis, Benjamin; Costanzo, Michael; Myers, Chad L.; Andrews, Brenda J.; Boone, Charles

Discovering genetic interactions bridging pathways in genome-wide association studies

NATURE COMMUNICATIONS

IF15.7

2019-09-19

OAAI

Fang, Gang; Wang, Wen; Paunic, Vanja; Heydari, Hamed; Costanzo, Michael; Liu, Xiaoye; Liu, Xiaotong; VanderSluis, Benjamin; Oately, Benjamin; Steinbach, Michael; Van Ness, Brian; Schadt, Eric E.; Pankratz, Nathan D.; Boone, Charles; Kumar, Vipin; Myers, Chad L.

Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase

microbial cell factories

IF3.9

2019-06-03

OAAI

Corcoles-Saez, Isaac; Ferat, Jean-Luc; Costanzo, Michael; Boone, Charles M.; Cha, Rita S.

Integrating genetic and protein-protein interaction networks maps a functional wiring diagram of a cell

CURRENT OPINION IN MICROBIOLOGY

IF7.5

2018-10-01

OAAI

VanderSluis, Benjamin; Costanzo, Michael; Bilmann, Maximilian; Ward, Henry N.; Myers, Chad L.; Andrews, Brenda J.; Boone, Charles

Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis

DEVELOPMENTAL CELL

IF8.7

2018-08-01

OAAI

Corcoles-Saez, Isaac; Dong, Kangzhen; Johnson, Anthony L.; Waskiewicz, Erik; Costanzo, Michael; Boone, Charles; Cha, Rita S.

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

GENETICS

IF5.1

2018-07-16

OAAI

Ciftci-Yilmaz, Sultan; Au, Wei-Chun; Mishra, Prashant K.; Eisenstatt, Jessica R.; Chang, Joy; Dawson, Anthony R.; Zhu, Iris; Rahman, Mahfuzur; Bilke, Sven; Costanzo, Michael; Baryshnikova, Anastasia; Myers, Chad L.; Meltzer, Paul S.; Landsman, David; Baker, Richard E.; Boone, Charles; Basrai, Munira A.

研究方向