Christoph A. Merten

ecole polytechnique federale de lausanne

29H指数

75论文数

5.0K被引数

收录论文 42

发表时间

Revealing therapeutic single-cell transcriptomic signatures using a simple classifier 利用简单分类器揭示治疗性单细胞转录组学特征

Cell Reports Methods

IF4.5

2026-09-18

OAAI

Xiaoli Ma; Yu Fen Samantha Seah; David Gfeller; Christoph A. Merten

Recovery of phenotypically sorted cells using droplet-digital microfluidics 使用液滴数字微流控技术回收表型分选细胞

lab on a chip

IF0

2025-07-23

OAAI

Zhiyang Deng; James M. Perry; Marian Weiss; Robert Genth; Alexis Autour; Christoph A. Merten; Steve C. C. Shih

Targeted barcoding of variable antibody domains and individual transcriptomes of the human B-cell repertoire using Link-Seq 使用link-seq对人类b细胞库的可变抗体结构域和单个转录组进行靶向条形码化

PNAS NEXUS

IF3.8

2025-01-09

OAAI

Hu, Hongxing; Zhou, Fan; Ma, Xiaoli; Brokstad, Karl Albert; Kolmar, Leonie; Girardot, Charles; Benes, Vladimir; Cox, Rebecca J.; Merten, Christoph A.

Fluorescence- activated droplet sequencing (FAD- seq) directly provides sequences of screening hits in antibody discovery

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-09-06

OAAI

Autour, Alexis; Merten, Christoph A.

Transcriptomics-based drug screening in 3D ex vivo patientderived breast cancer model and patient biopsy for personalized therapy

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Zhang, Yueyun; Ronchi, Carlos Henrique Venturi; Ambrosini, Giovanna; Liu, Yuanlong; Aouad, Patrick; Matvienko, Daria; Merten, Christoph; Brisken, Cathrin

Screening for drivers of SARS-CoV-2 uptake

NATURE BIOMEDICAL ENGINEERING

IF26.6

2023-12-29

PREAI

Autour, Alexis; Merten, Christoph A.

iSort enables automated complex microfluidic droplet sorting in an effort to democratize technology

CELL REPORTS METHODS

IF4.5

2023-05-01

OAAI

Panwar, Jatin; Utharala, Ramesh; Fennelly, Laura; Frenzel, Daniel; Merten, Christoph A.

Design and construction of a microfluidics workstation for high-throughput multi-wavelength fluorescence and transmittance activated droplet analysis and sorting

NATURE PROTOCOLS

IF16

2023-01-27

PREAI

Panwar, Jatin; Autour, Alexis; Merten, Christoph A.

Fluorescence crosstalk reduction by modulated excitation-synchronous acquisition for multispectral analysis in high-throughput droplet microfluidics

LAB ON A CHIP

IF5.4

2023-01-01

OAAI

Panwar, Jatin; Merten, Christoph A. A.

Large scale microfluidic CRISPR screening for increased amylase secretion in yeast

LAB ON A CHIP

IF5.4

2023-01-01

OAAI

Johansson, S. Andreas; Dulermo, Thierry; Jann, Cosimo; Smith, Justin D.; Pryszlak, Anna; Pignede, Georges; Schraivogel, Daniel; Colavizza, Didier; Desfougeres, Thomas; Rave, Christophe; Farwick, Alexander; Merten, Christoph A.; Roy, Kevin R.; Wei, Wu; Steinmetz, Lars M.

Technological and computational advances driving high-throughput oncology

TRENDS IN CELL BIOLOGY

IF18.1

2022-11-01

OAAI

Kolmar, Leonie; Autour, Alexis; Ma, Xiaoli; Vergier, Blandine; Eduati, Federica; Merten, Christoph A.

A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets

NATURE PROTOCOLS

IF16

2022-10-19

PREAI

Utharala, Ramesh; Grab, Anna; Vafaizadeh, Vida; Peschke, Nicolas; Ballinger, Martine; Turei, Denes; Tuechler, Nadine; Ma, Wenwei; Ivanova, Olga; Ortiz, Alejandro Gil; Saez-Rodriguez, Julio; Merten, Christoph A.

Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets Combi-seq用于在单细胞液滴中使用确定性条形码对药物组合进行基于转录组的多重分析

NATURE COMMUNICATIONS

IF15.7

2022-08-01

OAAI

Mathur, L.; Szalai, B.; Du, N. H.; Utharala, R.; Ballinger, M.; Landry, J. J. M.; Ryckelynck, M.; Benes, V; Saez-Rodriguez, J.; Merten, C. A.

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics

CELL REPORTS METHODS

IF4.5

2022-01-01

OAAI

Pryszlak, Anna; Wenzel, Tobias; Seitz, Kiley West; Hildebrand, Falk; Kartal, Ece; Cosenza, Marco Raffaele; Benes, Vladimir; Bork, Peer; Merten, Christoph A.

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies (vol 16, e8664, 2020)

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2020-06-16

OAAI

Eduati, Federica; Jaaks, Patricia; Wappler, Jessica; Cramer, Thorsten; Merten, Christoph A.; Garnett, Mathew J.; Saez-Rodriguez, Julio

Targeted Perturb-seq enables genome-scale genetic screens in single cells

NATURE METHODS

IF32.1

2020-06-01

139

OAAI

Schraivogel, Daniel; Gschwind, Andreas R.; Milbank, Jennifer H.; Leonce, Daniel R.; Jakob, Petra; Mathur, Lukas; Korbel, Jan O.; Merten, Christoph A.; Velten, Lars; Steinmetz, Lars M.

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies 来自癌症活检筛查的信号通路的患者特异性逻辑模型，以优先考虑个性化联合治疗

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2020-02-19

OAAI

Eduati, Federica; Jaaks, Patricia; Wappler, Jessica; Cramer, Thorsten; Merten, Christoph A.; Garnett, Mathew J.; Saez-Rodriguez, Julio

Microfluidics as an Enabling Technology for Personalized Cancer Therapy

SMALL

IF12.1

2019-11-20

OAAI

Mathur, Lukas; Ballinger, Martine; Utharala, Ramesh; Merten, Christoph A.

Microfluidics as an Emerging Precision Tool in Developmental Biology

DEVELOPMENTAL CELL

IF8.7

2019-02-01

OAAI

Sonnen, Katharina F.; Merten, Christoph A.

A microfluidics platform for combinatorial drug screening on cancer biopsies

NATURE COMMUNICATIONS

IF15.7

2018-06-22

188

OAAI

Eduati, Federica; Utharala, Ramesh; Madhavan, Dharanija; Neumann, Ulf Peter; Longerich, Thomas; Cramer, Thorsten; Saez-Rodriguez, Julio; Merten, Christoph A.

研究方向