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Simone Difilippantonio

Frederick National Laboratory for Cancer Research
H指数:30
被引数:5,016

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Therapeutic NAMPT inhibition reveals a targetable metabolic vulnerability in neuroblastoma

治疗性NAMPT抑制揭示了神经母细胞瘤中可靶向的代谢易损性

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2026-08-050
OAAI
Sophia Varriano; Amy Yu; Abantika Chakraborty; Ariana E. Nelson; Amy James; Kristine Isanogle; Nimit Patel; Caleb Kim; Unsun Lee; Victor J. Collins; Grace B. McKay-Corkum; Ye Yang; Xiaohu Zhang; Crystal McKnight; Kelli Wilson; Carleen Klumpp-Thomas; Michele Ceribelli; David Holland; Ming Sun; Gitanjali Asampille; Ying Wu; Krithika Bhuvaneshwar; Brad Gouker; Donna Butcher; Bhushan L. Thakur; Arnulfo Mendoza; Sameer H. Issaq; Mirit I. Aladjem; Baktiar O. Karim; Jack F. Shern; Parthav Jailwala; Simone Difilippantonio; Craig J. Thomas; Daniel R. Crooks; Rosa Nguyen; Carol J. Thiele; Christine M. Heske
The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC

Cyclin C-CDK8/19介导激酶模块调控PRCC-TFE3驱动的肾上皮细胞衰老及TFE3-RCC中的肿瘤发生。

Neoplasia
IF7.7
2026-03-160
OAAI
Shoichiro Kuroda; Shintaro Funasaki; Hidekazu Nishizawa; Laura S. Schmidt; Ryoma Kurahashi; Takaaki Ito; Yuichiro Arima; Miwa Tanaka; Atsuya Kitada; Amy M. James; Hisashi Hasumi; Ryosuke Jikuya; Kazuhide Makiyama; Daisuke Kurotaki; Takashi Minami; Simone Difilippantonio; W. Marston Linehan; Yuichi Oike; Tomohiro Sawa; Yasuhito Tanaka
Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral-Like Immunomodulatory Responses and Potent Adjuvant Activity
ADVANCED FUNCTIONAL MATERIALS
IF19
2026-01-010
OAAI
Panigaj, Martin; Newton, Hannah S.; Wang, Jian; Pandey, Laxmi; Avilla, Yelixza I.; Nguyen, Phong; Chandler, Morgan; Halman, Justin; Radwan, Yasmine; Smith, Stephanie; Edmondson, Elijah; Difilippantonio, Simone; Sanders, Chelsea; Tran, Bao; Zhao, Yongmei; Xie, Shaojun; Cedrone, Edward; Neun, Barry W.; Wanunu, Meni; Dokholyan, Nikolay V.; Dobrovolskaia, Marina A.; Afonin, Kirill A.
A CSF-1R inhibitor both prevents and treats triple-negative breast cancer brain metastases in hematogenous preclinical models

一种CSF-1R抑制剂在血液传播的预临床模型中既可预防又可治疗三阴性乳腺癌脑转移瘤

Clinical & Experimental Metastasis
IF3.2
2025-08-040
OAAI
Wei Zhang; Samiur Rahman; Alex M. L. Wu; Kristine Isanogle; Christina Robinson; Dinesh Kumar; Imran Khan; Debbie Wei; Alexandra S. Zimmer; Takeo Fujii; Simone Difilippantonio; Stanley Lipkowitz; Patricia Steeg
Immune profile diversity is achieved with synthetic TLR4 agonists combined with the RG1-VLP vaccine in mice

通过合成TLR4激动剂与RG1-VLP疫苗联合使用，可在小鼠中实现免疫谱系多样性。

VACCINE
IF3.5
2025-01-011
OAAI
Matthews, Rebecca L.; Khan, Nazneen; Beckman, Bradley; Sharma, Simran; Dietz, Zackary; Picking, William D.; Izmirlian, Grant; Sanders, Chelsea; Stocks, Stacy M.; Difilippantonio, Simone; Kirnbauer, Reinhard; Roden, Richard B.; Pinto, Ligia A.; Shoemaker, Robert H.; Ernst, Robert K.; Marshall, Jason D.
Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-10-231
OAAI
Hoyt, Scott B.; Finocchio, Chris J.; Croll, Elizabeth; Tawa, Gregory J.; Li, Huixu; Ma, Li; Li, Kaikai; Liu, Li; Li, Ranran; Zhang, Xiaohu; Wilson, Kelli; Xu, Xin; Shah, Pranav; Williams, Jordan; Fang, Yuhong; Bolanos, Lyndsey C.; Gracia-Maldonado, Gabriel; Kolt, Amal; Robinson, Christina; Free, Jessica; Edmondson, Elijah F.; Difilippantonio, Simone; Jones, LaQuita M.; Culver-Cochran, Ashley E.; Rosenbaum, Jan S.; Starczynowski, Daniel T.; Thomas, Craig J.
Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the Novel NAMPT Inhibitor OT-82
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-10-120
PRE
Najera, Susana S.; Ricketts, Christopher J.; Schmidt, Laura S.; Medina, Julia I.; Saito, Keita; Ileva, Lilia; Brender, Jeffrey R.; James, Amy M.; Peer, Cody J.; Gouker, Brad; Karim, Baktiar O.; Chernova, Olga; Wells, Catherine; Wei, Ming-Hui; Yang, Youfeng; Zhang, Xiaohu; Klumpp-Thomas, Carleen; Travers, Jameson; Chen, Lu; Wilson, Kelli M.; Issaq, Sameer H.; Figg, William D.; Difilippantonio, Simone; Kalen, Joseph D.; Krishna, Murali C.; Thomas, Craig J.; Ceribelli, Michele; Heske, Christine M.; Crooks, Daniel R.; Meier, Jordan L.
Toward a CRISPR- based mouse model of Vhl- deficient clear cell kidney cancer: Initial experience and lessons learned
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-10-040
OAAI
Stransky, Laura A.; Gao, Wenhua; Schmidt, Laura S.; Bi, Kevin; Ricketts, Christopher J.; Ramesh, Vijyendra; James, Amy; Difilippantonio, Simone; Ileva, Lilia; Kalen, Joseph D.; Karim, Baktiar; Jeon, Albert; Morgan, Tamara; Warner, Andrew C.; Turan, Sevilay; Unite, Joanne; Tran, Bao; Choudhari, Sulbha; Zhao, Yongmei; Linn, Douglas E.; Yun, Changhong; Dhandapani, Sripriya; Parab, Vaishali; Pinheiro, Elaine M.; Morris, Nicole; He, Lixia; Vigeant, Sean M.; Pignon, Jean- Christophe; Ivins, Maura Sticco --; Signoretti, Sabina; Allen, Eliezer M. Van; Linehan, W. Marston; Kaelin, William G.
Gα13 restricts nutrient driven proliferation in mucosal germinal centers
NATURE IMMUNOLOGY
IF27.6
2024-07-180
OAAI
Nguyen, Hang T.; Li, Moyi; Vadakath, Rahul; Henke, Keirstin A.; Tran, Tam C.; Li, Huifang; Yamadi, Maryam; Darbha, Sriranjani; Yang, Yandan; Kabat, Juraj; Albright, Anne R.; Centeno, Enoc Granados; Phelan, James D.; Roulland, Sandrine; Huang, Da Wei; Kelly, Michael C.; Young, Ryan M.; Pittaluga, Stefania; Difilippantonio, Simone; Muppidi, Jagan R.
Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+brain metastases of breast cancer

trastuzumab，人IgG和biocytin-tmr在实验性乳腺癌HER2脑转移中的不同摄取和消除特征

NEURO-ONCOLOGY
IF13.4
2024-02-132
OA
Silvestri, Vanesa L.; Tran, Andy D.; Chung, Monika; Chung, Natalie; Gril, Brunilde; Robinson, Christina; Difilippantonio, Simone; Wei, Debbie; Kruhlak, Michael J.; Peer, Cody J.; Figg, W. Douglas; Khan, Imran; Steeg, Patricia S.
Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
CELL REPORTS
IF6.9
2023-12-0110
OAAI
Feng, Yang; Lee, Jaewon; Yang, Liping; Hilton, Mary Beth; Morris, Karen; Seaman, Steven; Edupuganti, Veera V. Shivaji R.; Hsu, Kuo-Sheng; Dower, Christopher; Yu, Guojun; So, Daeho; Bajgain, Pradip; Zhu, Zhongyu; Dimitrov, Dimiter S.; Patel, Nimit L.; Robinson, Christina M.; Difilippantonio, Simone; Dyba, Marzena; Corbel, Amanda; Basuli, Falguni; Swenson, Rolf E.; Kalen, Joseph D.; Suthe, Sreedhar Reddy; Hussain, Myer; Italia, James S.; Souders, Colby A.; Gao, Ling; Schnermann, Martin J.; Croix, Brad St.
Organoids and metastatic orthotopic mouse model for mismatch repair-deficient colorectal cancer

错配修复缺陷型结直肠癌的类器官和转移性原位小鼠模型

FRONTIERS IN ONCOLOGY
IF3.3
2023-09-082
OAAI
Song, Yurong; Kerr, Travis D.; Sanders, Chelsea; Dai, Lisheng; Baxter, Shaneen S.; Somerville, Brandon; Baugher, Ryan N.; Mellott, Stephanie D.; Young, Todd B.; Lawhorn, Heidi E.; Plona, Teri M.; Xu, Bingfang; Wei, Lei; Hu, Qiang; Liu, Song; Hutson, Alan; Karim, Baktiar; Burkett, Sandra; Difilippantonio, Simone; Pinto, Ligia; Gebert, Johannes; Kloor, Matthias; Lipkin, Steven M.; Sei, Shizuko; Shoemaker, Robert H.

研究方向

暂未获取到该数据
C
Christina M. Robinson
H 指数:14论文数:119被引数:1,171
P
Patricia S. Steeg
H 指数:86论文数:591被引数:3.2万
B
Baktiar Karim
H 指数:31论文数:249被引数:4,506
A
Amy James
H 指数:7论文数:82被引数:131
C
Chelsea Sanders
H 指数:13论文数:52被引数:902
A
André Nussenzweig
H 指数:86论文数:388被引数:3.5万
N
Nimit L. Patel
H 指数:19论文数:65被引数:1,750
J
Joseph D. Kalen
H 指数:19论文数:104被引数:1,521
K
Kristine A. Isanogle
H 指数:6论文数:104被引数:252
L
Lígia A. Pinto
H 指数:48论文数:259被引数:8,034