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S

Shannon Coy

Brigham and Women's Hospital
H指数:23
被引数:6,278

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工作经历

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荣誉奖项

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Meningioma microenvironment harbors a rich immune landscape that evolves with biological state

脑膜瘤微环境富集一个随生物学状态演变的丰富免疫景观

Neuro-Oncology
IF13.4
2026-03-010
PRE
Guo, Xiaopeng; Moynihan, Zachary A.; Driver, Joseph; Patel, Ruchit, V; Bhave, Varun M.; Maury, Eduardo A.; Knelson, Erik H.; Guo, Hong; Lin, Jia-Ren; Coy, Shannon M.; Wang, Anthony; Gupta, Saksham; Hoffman, Samantha E.; Dunn, Ian F.; Dunn, Gavin P.; Petti, Allegra; Choi, Bryan D.; Choudhury, Abrar; Raleigh, David R.; Wei, Kevin; Reardon, David A.; Barbie, David; Lederer, James A.; Santagata, Sandro; Bi, Wenya Linda
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
Science Translational Medicine
IF14.6
2026-01-210
PRE
Erica M. Pimenta; Amanda E. Garza; Sabrina Y. Camp; Jihye Park; Samantha E. Hoffman; Laura Valderrábano; Jingxin Fu; Kevin Bi; Maximilian T. Carson; Julie Karam; Breanna M. Titchen; Sofia Medjahed; Melin J. Khandekar; Erin Shannon; Yun Jee Kang; Shannon Coy; Jia-Ren Lin; Anwesha Nag; Aaron R. Thorner; William J. Gibson; Sandro Santagata; Chandrajit P. Raut; Jason L. Hornick; Priscilla Merriam; Nicole L. Solimini; Suzanne George; George D. Demetri; Eliezer M. Van Allen
Integrated multiomic profiling identifies genomic and immune microenvironmental changes as candidate resistance mechanisms to PD-1 blockade in high-grade meningiomas

整合多组学分析鉴定出基因组改变和免疫微环境变化为高级别脑膜瘤对PD-1阻断治疗的候选耐药机制

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Gritsch, David; Jia-Ren, Lin; Haehnel, Philipp; Coy, Shannon; Zhang, Britney; Sullivan, Emily; Nayyar, Naema; Cahill, Daniel P.; Barker, Fred G.; Gerstner, Elizabeth R.; Santagata, Sandro; Brastianos, Priscilla K.
Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Kader, Tanjina; Lin, Jia-Ren; Coy, Shannon; Hug, Clemens; Chen, Yu-An; Pelletier, Roxanne J.; Leon, Mariana; Lee, John; Xu, Yi-Lin; Yapp, Clarence; Shih, Natalie; Mingo, Gabriel; Jung, Euihye; Rathore, Srishti; Agudo, Judith; Drescher, Charles; Sorger, Peter K.; Drapkin, Ronny; Santagata, Sandro
High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers

高度复杂的免疫荧光成像和相同组织切片的传统组织学，用于发现基于图像的生物标志物

NATURE CANCER
IF28.5
2023-06-2240
OAAI
Lin, Jia-Ren; Chen, Yu-An; Campton, Daniel; Cooper, Jeremy; Coy, Shannon; Yapp, Clarence; Tefft, Juliann B.; McCarty, Erin; Ligon, Keith L.; Rodig, Scott J.; Reese, Steven; George, Tad; Santagata, Sandro; Sorger, Peter K.
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma
NATURE COMMUNICATIONS
IF15.7
2022-08-1635
OAAI
Coy, Shannon; Wang, Shu; Stopka, Sylwia A.; Lin, Jia-Ren; Yapp, Clarence; Ritch, Cecily C.; Salhi, Lisa; Baker, Gregory J.; Rashid, Rumana; Baquer, Gerard; Regan, Michael; Khadka, Prasidda; Cole, Kristina A.; Hwang, Jaeho; Wen, Patrick Y.; Bandopadhayay, Pratiti; Santi, Mariarita; De Raedt, Thomas; Ligon, Keith L.; Agar, Nathalie Y. R.; Sorger, Peter K.; Touat, Mehdi; Santagata, Sandro
Copper induces cell death by targeting lipoylated TCA cycle proteins

铜通过靶向脂化TCA循环蛋白诱导细胞死亡

Science
IF45.8
2022-01-010
OA
Peter Tsvetkov; Shannon Coy; Boryana Petrova; Margaret B. Dreishpoon; Ana Verma; Mai Abdusamad; Jordan Rossen; Lena M. Joesch-Cohen; Ranad Humeidi; Ryan D. Spangler; John K. Eaton; Evgeni M. Frenkel; Mustafa Kocak; Steven M. Corsello; Svetlana Lutsenko; Naama Kanarek; Sandro Santagata; Todd R. Golub
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma
NATURE COMMUNICATIONS
IF15.7
2019-06-0338
OAAI
Bandopadhayay, Pratiti; Piccioni, Federica; O'Rourke, Ryan; Ho, Patricia; Gonzalez, Elizabeth M.; Buchan, Graham; Qian, Kenin; Gionet, Gabrielle; Girard, Emily; Coxon, Margo; Rees, Matthew G.; Brenan, Lisa; Dubois, Frank; Shapira, Ofer; Greenwald, Noah F.; Pages, Melanie; Iniguez, Amanda Balboni; Paolella, Brenton R.; Meng, Alice; Sinai, Claire; Roti, Giovanni; Dharia, Neekesh V.; Creech, Amanda; Tanenbaum, Benjamin; Khadka, Prasidda; Tracy, Adam; Tiv, Hong L.; Hong, Andrew L.; Coy, Shannon; Rashid, Rumana; Lin, Jia-Ren; Cowley, Glenn S.; Lam, Fred C.; Goodale, Amy; Lee, Yenarae; Schoolcraft, Kathleen; Vazquez, Francisca; Hahn, William C.; Tsherniak, Aviad; Bradner, James E.; Yaffe, Michael B.; Milde, Till; Pfister, Stefan M.; Qi, Jun; Schenone, Monica; Carr, Steven A.; Ligon, Keith L.; Kieran, Mark W.; Santagata, Sandro; Olson, James M.; Gokhale, Prafulla C.; Jaffe, Jacob D.; Root, David E.; Stegmaier, Kimberly; Johannessen, Cory M.; Beroukhim, Rameen

研究方向

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S
Sandro Santagata
H 指数:90论文数:719被引数:3.2万
J
Jia‐Ren Lin
H 指数:39论文数:294被引数:1.4万
P
Peter K. Sorger
H 指数:117论文数:869被引数:5.4万
R
Rumana Rashid
H 指数:23论文数:127被引数:2,578
K
Keith L. Ligon
H 指数:113论文数:1,205被引数:5.0万
K
Kimon Bekelis
H 指数:37论文数:198被引数:4,475
M
Mark W. Kieran
H 指数:93论文数:559被引数:3.0万
W
Wenya Linda Bi
H 指数:59论文数:438被引数:1.5万
C
Clarence Yapp
H 指数:39论文数:204被引数:6,620
S
Symeon Missios
H 指数:36论文数:179被引数:3,707