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J

Jia-Ren Lin

Harvard University
H指数:39
被引数:1.4万

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Single-cell and spatial mapping reveals GCLC+ mesenchymal tumor cells linked with favorable outcomes in TNBC

单细胞和空间图谱揭示GCLC+间充质肿瘤细胞与TNBC良好预后的关联

Communications Biology
IF5.1
2026-10-230
OAAI
Nomeda Girnius; Tuulia Vallius; Wenqing Chen; Inga-Maria Launonen; Sara Palomino-Echeverria; Jia-Ren Lin; Caitlin E. Mills; Silja Kauppila; Pauliina Kronqvist; Antti Ellonen; Merja Perala; Eloise Withnell; Yu-An Chen; Maria Secrier; Sandro Santagata; Peter K. Sorger; Anniina Färkkilä
RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation

RNF43 p.G659fs通过PI3K/AKT/mTOR信号通路和HLA-E上调导致MSI-high结直肠癌中自然杀伤细胞功能障碍

Science Advances
IF12.5
2026-09-230
OA
Pushpamali De Silva; Samantha Fitzgerald; Jules Cazaubiel; Kristin Qian; Matan Hofree; Jia-Ren Lin; Roxanne Pelletier; Mariana Lopez Leon; Phuong Vu Mai Ho; Yasutoshi Takashima; Juha P Väyrynen; Kosuke Matsuda; Tomotaka Ugai; Dane Ford-Roshon; Pratyusha Bala; Nir Hacohen; Kimmie Ng; Jonathan A. Nowak; Shuji Ogino; Peter K. Sorger; Marios Giannakis
Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial

奥拉帕尼与尼沃鲁单抗联合治疗微卫星稳定型结直肠癌：一项1/2期临床试验

Nature Communications
IF15.7
2026-07-230
OA
Eric S. Christenson; Jeremiah A. Wala; Rose Parkinson; Natalie B. Collins; Christopher Jakubowski; Jia-Ren Lin; Kristin Qian; Jiayun Lu; Hao Wang; Won Jin Ho; Sabrina Chan; Ewa Kulikowicz; Rachel Klein; Yvette Cetasaan; Emma Johnson; Maureen Berg; Jeffrey A. Meyerhardt; Dung T. Le; Benjamin L. Schlechter; Ilene Browner; Lei Zheng; Harshabad Singh; Ross Donehower; Elizabeth M. Jaffee; Peter K. Sorger; Marios Giannakis; Nilofer Azad
Live-cell Pick-Seq (LiP-Seq): Interrogating ultra-rare mantle cell lymphoma persistent cells after CART19 therapy

活细胞Pick-Seq (LiP-Seq)：CART19疗法后检测超罕见套细胞淋巴瘤持续性细胞

Blood Advances
IF7.1
2026-03-230
OAAI
Ran Xu; Gongwei Wu; Siobhan Rice; Matthew Booker; Jenalyn Weekes; Hayden Bell; Yifei Gao; Ajit J. Nirmal; Huiyun Liu; Zoe Ciantra; Qingyu Luo; Amanda Fortune; Karley Whalen; Timothy Guanci; Yifei Wan; Abner Louissaint; Joshua J. Nordberg; Jia-Ren Lin; Michael Hemann; Scott R. Manalis
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
Science Translational Medicine
IF14.6
2026-01-210
PRE
Erica M. Pimenta; Amanda E. Garza; Sabrina Y. Camp; Jihye Park; Samantha E. Hoffman; Laura Valderrábano; Jingxin Fu; Kevin Bi; Maximilian T. Carson; Julie Karam; Breanna M. Titchen; Sofia Medjahed; Melin J. Khandekar; Erin Shannon; Yun Jee Kang; Shannon Coy; Jia-Ren Lin; Anwesha Nag; Aaron R. Thorner; William J. Gibson; Sandro Santagata; Chandrajit P. Raut; Jason L. Hornick; Priscilla Merriam; Nicole L. Solimini; Suzanne George; George D. Demetri; Eliezer M. Van Allen
Immune profiling in a living human recipient of a gene-edited pig kidney

在基因编辑的猪肾的活人类受体中进行免疫分析

Nature Medicine
IF50
2026-01-080
OAAI
Guilherme T. Ribas; André F. Cunha; Jonathan P. Avila; Alessia Giarraputo; Leela Morena; Karina Lima; Rodrigo B. Gassen; Jia-Yun Chen; Jia-Ren Lin; Sandro Santagata; Claire T. Avillach; Birgitta A. Ryback; Martin S. Lindner; Sivan Bercovici; Ivy A. Rosales; Tatsuo Kawai; Helder I. Nakaya; Robert B. Colvin; Thiago J. Borges; Leonardo V. Riella
Spatial Profiling of Elements through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging

基质辅助激光解吸电离质谱成像技术对元素的时空分布表征

ANALYTICAL CHEMISTRY
IF6.7
2025-11-010
PRE
Stopka, Sylwia A.; Bodineau, Clement; Baquer, Gerard; Lin, Jia-Ren; Hossain, Md Amin; Martinez, Camilla J.; Regan, Michael S.; Ruiz, Daniela; Fletcher, Stecia-Marie; Pourquie, Olivier; Lutsenko, Svetlana; Payne, Connor N.; Agar, Jeffrey N.; Mazitschek, Ralph; Mcdannold, Nathan J.; Sorger, Peter K.; Santagata, Sandro; Agar, Nathalie Y. R.
Integrated multiomic profiling identifies genomic and immune microenvironmental changes as candidate resistance mechanisms to PD-1 blockade in high-grade meningiomas

整合多组学分析鉴定出基因组改变和免疫微环境变化为高级别脑膜瘤对PD-1阻断治疗的候选耐药机制

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Gritsch, David; Jia-Ren, Lin; Haehnel, Philipp; Coy, Shannon; Zhang, Britney; Sullivan, Emily; Nayyar, Naema; Cahill, Daniel P.; Barker, Fred G.; Gerstner, Elizabeth R.; Santagata, Sandro; Brastianos, Priscilla K.
Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa

HS患者三级淋巴样结构中皮肤免疫-间质细胞间的相互作用促进了自身免疫病的发生发展。

IMMUNITY
IF26.3
2024-12-013
PRE
Yu, Wei-Wen; Barrett, Joy N. P.; Tong, Jie; Lin, Meng-Ju; Marohn, Meaghan; Devlin, Joseph C.; Herrera, Alberto; Remark, Juliana; Levine, Jamie; Liu, Pei-Kang; Fang, Victoria; Zellmer, Abigail M.; Oldridge, Derek A.; Wherry, E. John; Lin, Jia-Ren; Chen, Jia-Yun; Sorger, Peter; Santagata, Sandro; Krueger, James G.; Ruggles, Kelly, V; Wang, Fei; Su, Chang; Koralov, Sergei B.; Wang, Jun; Chiu, Ernest S.; Lu, Catherine P.
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

AKT和EZH2抑制剂通过劫持退化机制杀死TNBCs

Nature
IF48.5
2024-10-090
OAAI
Amy E. Schade; Naiara Perurena; Yoona Yang; Carrie L. Rodriguez; Anjana Krishnan; Alycia Gardner; Patrick Loi; Yilin Xu; Van T. M. Nguyen; G. M. Mastellone; Natalie F. Pilla; Marina Watanabe; Keiichi Ota; Rachel A. Davis; Kaia Mattioli; Dongxi Xiang; Jason J. Zoeller; Jia-Ren Lin; Stefania Morganti; Ana C. Garrido-Castro; Sara M. Tolaney; Zhe Li; David A. Barbie; Peter K. Sorger; Kristian Helin; Sandro Santagata; Simon R. V. Knott; Karen Cichowski
Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
CANCER DISCOVERY
IF33.3
2024-08-120
OAAI
Loi, Patrick; Schade, Amy E.; Rodriguez, Carrie L.; Krishnan, Anjana; Perurena, Naiara; Nguyen, Van T. M.; Xu, Yilin; Watanabe, Marina; Davis, Rachel A.; Gardner, Alycia; Pilla, Natalie F.; Mattioli, Kaia; Popow, Olesja; Gunduz, Nuray; Lannagan, Tamsin R. M.; Fitzgerald, Samantha; Sicinska, Ewa T.; Lin, Jia-Ren; Tan, William; Brais, Lauren K.; Haigis, Kevin M.; Giannakis, Marios; Ng, Kimmie; Santagata, Sandro; Helin, Kristian; Sansom, Owen J.; Cichowski, Karen
Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Kader, Tanjina; Lin, Jia-Ren; Coy, Shannon; Hug, Clemens; Chen, Yu-An; Pelletier, Roxanne J.; Leon, Mariana; Lee, John; Xu, Yi-Lin; Yapp, Clarence; Shih, Natalie; Mingo, Gabriel; Jung, Euihye; Rathore, Srishti; Agudo, Judith; Drescher, Charles; Sorger, Peter K.; Drapkin, Ronny; Santagata, Sandro
Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer
NPJ BREAST CANCER
IF7.6
2024-01-022
OA
Guerriero, Jennifer L.; Lin, Jia-Ren; Pastorello, Ricardo G.; Du, Ziming; Chen, Yu-An; Townsend, Madeline G.; Shimada, Kenichi; Hughes, Melissa E.; Ren, Siyang; Tayob, Nabihah; Zheng, Kelly; Mei, Shaolin; Patterson, Alyssa; Taneja, Krishan L.; Metzger, Otto; Tolaney, Sara M.; Lin, Nancy U.; Dillon, Deborah A.; Schnitt, Stuart J.; Sorger, Peter K.; Mittendorf, Elizabeth A.; Santagata, Sandro
Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer
CANCER RESEARCH
IF16.6
2023-07-142
OAAI
Hermida-Prado, Francisco; Xie, Yingtian; Sherman, Shira; Nagy, Zsuzsanna; Russo, Douglas; Akhshi, Tara; Chu, Zhengtao; Feit, Avery; Campisi, Marco; Chen, Minyue; Nardone, Agostina; Guarducci, Cristina; Lim, Klothilda; Font-Tello, Alba; Lee, Irene; Garcia-Pedrero, Juana; Canadas, Israel; Agudo, Judith; Huang, Ying; Sella, Tal; Jin, Qingchun; Tayob, Nabihah; Mittendorf, Elizabeth A.; Tolaney, Sara M.; Qiu, Xintao; Long, Henry; Symmans, William F.; Lin, Jia-Ren; Santagata, Sandro; Bedrosian, Isabelle; Yardley, Denise A.; Mayer, Ingrid A.; Richardson, Edward T.; Oliveira, Giacomo; Wu, Catherine J.; Schuster, Eugene F.; Dowsett, Mitch; Welm, Alana L.; Barbie, David; Metzger, Otto; Jeselsohn, Rinath

研究方向

暂未获取到该数据
P
Peter K. Sorger
H 指数:117论文数:869被引数:5.4万
S
Sandro Santagata
H 指数:90论文数:719被引数:3.2万
B
Benjamin Izar
H 指数:46论文数:292被引数:1.8万
G
Gregory J. Baker
H 指数:23论文数:107被引数:3,001
S
Shannon Coy
H 指数:23论文数:113被引数:6,278
E
Elizabeth A. Mittendorf
H 指数:82论文数:1,176被引数:2.9万
C
Clarence Yapp
H 指数:39论文数:204被引数:6,620
Z
Zoltan Maliga
H 指数:33论文数:106被引数:6,968
S
Shaolin Mei
H 指数:12论文数:54被引数:3,331
D
Deborah Dillon
H 指数:46论文数:321被引数:8,886