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K

Kaat Durinck

faculty of medicine & health sciences

22H指数
108论文数
1.7K被引数
收录论文 45
发表时间
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Converting lysosomes into photothermal organelles enables nanoparticle-free tumor ablation via intracellular vapor bubbles将溶酶体转化为光热细胞器通过细胞内蒸汽泡实现无纳米粒子的肿瘤消融
errScience Advances
IF12.5
err2026-09-25
err0
errOAAI
errTao Lu; Cristina Muntean; Félix Sauvage; Deep Punj; Herlinde De Keersmaecker; Femke Baeke; Riet De Rycke; Kelly Lemeire; Philippe Tummers; Weiran Li; Chloë De Clercq; Bernd Vanmeerhaeghe; Kaat Durinck; Olivier De Wever; Katrien Remaut; Kevin Braeckmans; Stefaan C. De Smedt; Koen Raemdonck
err分享
err收藏
A functional landscape for chromosome 17q in neuroblastoma: balancing replication stress and genomic stability17号染色体长臂17q在神经母细胞瘤中的功能景观：平衡复制应激与基因组稳定性
errBritish Journal of Cancer
IF6.8
err2026-08-07
err0
errOAAI
errElien Hilgert; Lisa Depestel; Nadine Van Roy; Stephen Roberts; Kaat Durinck; Frank Speleman
err分享
err收藏
Beyond the gap: moonlighting functions of connexins in cancer超越缝隙：连接蛋白在癌症中的兼职功能
errCell Communication and Signaling
IF8.9
err2026-08-04
err0
errOAAI
errCarolien Van Damme; Lisa Depestel; Sven Eyckerman; Kaat Durinck
err分享
err收藏
A living biobank of sarcoma patient-derived cell cultures reveals multi-omic and functional insights that capture disease heterogeneity肉瘤患者来源细胞培养物的活体生物银行揭示可捕捉疾病异质性的多组学和功能见解
errClinical and Translational Medicine
IF6.8
err2026-07-30
err0
errOAAI
errStefanie Gijsels; Suzanne Fischer; David Creytens; Sándor Dedeyne; Felix De Vuyst; Cláudio Pinheiro; Fleur Cordier; Sarah-Lee Bekaert; Nadine Van Roy; Kaat Durinck; Jarne Pauwels; Kris Gevaert; Pieter Mestdagh; Jo Vandesompele; Pekka Rappu; Jyrki Heino; An Hendrix; Gabrielle H. van Ramshorst; Gwen Sys; Olivier De Wever
err分享
err收藏
RUVBL1 and RUVBL2 are druggable MYC effector regulators in neuroblastoma cellsRUVBL1和RUVBL2是神经母细胞瘤细胞中可成药性的MYC效应物调控因子
erriScience
IF4.1
err2026-04-17
err0
errOAAI
errSiaw, Joachim Tetteh; Claeys, Arne; Lai, Wei-Yun; Borenas, Marcus; Hilgert, Elien; Bekaert, Sarah-Lee; Sanders, Ellen; Kaya, Irem; Van Dorpe, Jo; Speleman, Frank; Durinck, Kaat; Hallberg, Bengt; Palmer, Ruth H.; Van den Eynden, Jimmy
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Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors通过利用第二代RRM2和CHK1抑制剂的协同潜力靶向神经母细胞瘤的复制应激
errCell Death & Disease
IF9.6
err2026-02-25
err0
errOAAI
errIris H. Nelen; Soetkin Leys; Sarah-Lee Bekaert; Fanny De Vloed; Fien Martens; Ellen Sanders; Angeline Praveena Enton Raj; Annika Jeschke; Shunya Ohmura; Thomas G. P. Grünewald; Liselot M. Mus; Tim Lammens; Nadine Van Roy; Bram De Wilde; Frank Speleman; Annelies Van Hemelryk; Lisa Depestel; Kaat Durinck
err分享
err收藏
Dual lipid modulation overcomes ferroptosis resistance in high-risk neuroblastoma双重脂质调控克服高危神经母细胞瘤的铁死亡抵抗
errCell Death & Differentiation
IF0
err2025-11-26
err0
errOAAI
errIne Koeken; Magali Walravens; Roberto Fernández-Acosta; Ruben Van Hoyweghen; Iuliana Vintea; Yingyi Kong; Bianka Golba; Jonas Dehairs; Ali Talebi; Johannes V. Swinnen; Kaat Durinck; Adriana Mañas; Shinya Toyokuni; Gerben Menschaert; Maria Fedorova; Bruno G. De Geest; Behrouz Hassannia; Tom Vanden Berghe
err分享
err收藏
Second-Generation AURKA-Targeting PROTACs: Structural Optimization toward in Vivo Degradation in Neuroblastoma第二代AURKA靶向PROTACs：神经母细胞瘤体内降解的结构优化
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errKrols, Simon; Rishfi, Muhammad; Martens, Fien; Van Hauwermeiren, Anouk; Sanders, Ellen; De Sutter, Pieter-Jan; Vermeulen, An; De Wever, Kaat; Bekaert, Sarah-Lee; Dolman, M. Emmy M.; Tax, Gabor; Kamili, Alvin; Fletcher, Jamie I.; Depestel, Lisa; De Wilde, Bram; Durinck, Kaat; Van Calenbergh, Serge
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err收藏
A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemiaPSIP1/LEDGF在T细胞急性淋巴细胞白血病中的双重作用
errSCIENCE ADVANCES
IF12.5
err2024-11-01
err1
errOAAI
errDemoen, Lisa; Matthijssens, Filip; Reunes, Lindy; Palhais, Bruno; Lintermans, Beatrice; T'Sas, Sara; Fijalkowski, Igor; Taminau, Joachim; Akele, Muluembet Z.; Van Belle, Siska; Taghon, Tom; Deforce, Dieter; Van Nieuwerburgh, Filip; Berx, Geert; Ntziachristos, Panagiotis; Debyser, Zeger; Durinck, Kaat; Pieters, Tim; Goossens, Steven; Van Vlierberghe, Pieter
err分享
err收藏
Post-operative minimal residual disease models to study metastatic relapse in soft-tissue sarcoma patient-derived xenografts
errCLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
err2023-06-06
err2
errOAAI
errFischer, Suzanne; Creytens, David; De Geyter, Sofie; De Vlieghere, Elly; Pattyn, Piet; Bekaert, Sarah-Lee; Durinck, Kaat; Van Roy, Nadine; Hendrix, An; Lapeire, Lore; Sys, Gwen; De Wever, Olivier
err分享
err收藏
Targeted AURKA degradation: Towards new therapeutic agents for neuroblastoma靶向AURKA降解: 神经母细胞瘤的新治疗药物
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-02-01
err14
errOAAI
errRishfi, Muhammad; Krols, Simon; Martens, Fien; Bekaert, Sarah-Lee; Sanders, Ellen; Eggermont, Aline; De Vloed, Fanny; Goulding, Joshua Robert; Risseeuw, Martijn; Molenaar, Jan; De Wilde, Bram; Van Calenbergh, Serge; Durinck, Kaat
err分享
err收藏
Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA来自肿瘤异种移植小鼠模型的液体活检的全转录组分析可以特异性监测肿瘤来源的细胞外RNA
errNAR CANCER
IF3.2
err2022-11-28
err6
errOAAI
errVermeirssen, Vanessa; Deleu, Jill; Morlion, Annelien; Everaert, Celine; De Wilde, Jilke; Anckaert, Jasper; Durinck, Kaat; Nuytens, Justine; Rishfi, Muhammad; Speleman, Frank; Van Droogenbroeck, Hanne; Verniers, Kimberly; Baietti, Maria Francesca; Albersen, Maarten; Leucci, Eleonora; Post, Edward; Best, Myron G.; Van Maerken, Tom; De Wilde, Bram; Vandesompele, Jo; Decock, Anneleen
err分享
err收藏
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
errSCIENCE ADVANCES
IF12.5
err2022-07-15
err13
errOAAI
errNunes, Carolina; Depestel, Lisa; Mus, Liselot; Keller, Kaylee M.; Delhaye, Louis; Louwagie, Amber; Rishfi, Muhammad; Whale, Alex; Kara, Neesha; Andrews, Simon R.; Dela Cruz, Filemon; You, Daoqi; Siddiquee, Armaan; Cologna, Camila Takeno; De Craemer, Sam; Dolman, Emmy; Bartenhagen, Christoph; De Vloed, Fanny; Sanders, Ellen; Eggermont, Aline; Bekaert, Sarah-Lee; Van Loocke, Wouter; Bek, Jan Willem; Dewyn, Givani; Loontiens, Siebe; Van Isterdael, Gert; Decaesteker, Bieke; Tilleman, Laurentijn; Van Nieuwerburgh, Filip; Vermeirssen, Vanessa; Van Neste, Christophe; Ghesquiere, Bart; Goossens, Steven; Eyckerman, Sven; De Preter, Katleen; Fischer, Matthias; Houseley, Jon; Molenaar, Jan; De Wilde, Bram; Roberts, Stephen S.; Durinck, Kaat; Speleman, Frank
err分享
err收藏
From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma
errJOURNAL OF PERSONALIZED MEDICINE
IF3
err2021-12-03
err2
errOAAI
errDecaesteker, Bieke; Durinck, Kaat; Van Roy, Nadine; De Wilde, Bram; Van Neste, Christophe; Van Haver, Stephane; Roberts, Stephen; De Preter, Katleen; Vermeirssen, Vanessa; Speleman, Frank
err分享
err收藏
MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells
errSCIENTIFIC REPORTS
IF3.9
err2021-07-14
err8
errOAAI
errZanotti, Sofia; Vanhauwaert, Suzanne; Van Neste, Christophe; Olexiouk, Volodimir; Van Laere, Jolien; Verschuuren, Marlies; Van der Meulen, Joni; Mus, Liselot M.; Durinck, Kaat; Tilleman, Laurentijn; Deforce, Dieter; Van Nieuwerburgh, Filip; Hogarty, Michael D.; Decaesteker, Bieke; De Vos, Winnok H.; Speleman, Frank
err分享
err收藏
Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
errGENES CHROMOSOMES & CANCER
IF2.8
err2021-01-09
err4
errOAAI
errMus, Liselot M.; Van Haver, Stephane; Popovic, Mina; Trypsteen, Wim; Lefever, Steve; Zeltner, Nadja; Ogando, Yudelca; Jacobs, Eva Z.; Denecker, Geertrui; Sanders, Ellen; Van Neste, Christophe; Vanhauwaert, Suzanne; Decaesteker, Bieke; Deforce, Dieter; Van Nieuwerburgh, Filip; Mestdagh, Pieter; Vandesompele, Jo; Menten, Bjorn; De Preter, Katleen; Studer, Lorenz; Heindryckx, Bjorn; Durinck, Kaat; Roberts, Stephen; Speleman, Frank
err分享
err收藏
Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes
errBLOOD ADVANCES
IF7.1
err2020-12-01
err38
errOAAI
errBuratin, Alessia; Paganin, Maddalena; Gaffo, Enrico; Dal Molin, Anna; Roels, Juliette; Germano, Giuseppe; Siddi, Maria Teresa; Serafin, Valentina; De Decker, Matthias; Gachet, Stephanie; Durinck, Kaat; Speleman, Frank; Taghon, Tom; te Kronnie, Geertruij; Van Vlierberghe, Pieter; Bortoluzzi, Stefania
err分享
err收藏
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models
errLEUKEMIA
IF13.4
err2020-06-26
err7
errOAAI
errLoontiens, Siebe; Vanhauwaert, Suzanne; Depestel, Lisa; Dewyn, Givani; Van Loocke, Wouter; Moore, Finola E.; Garcia, Elaine G.; Batchelor, Lance; Borga, Chiara; Squiban, Barbara; Malone-Perez, Megan; Volders, Pieter-Jan; Olexiouk, Volodimir; Van Vlierberghe, Pieter; Langenau, David M.; Frazer, J. Kimble; Durinck, Kaat; Speleman, Frank
err分享
err收藏
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
errEMBO REPORTS
IF6.2
err2020-04-07
err27
errOAAI
errDolens, Anne-Catherine; Durinck, Kaat; Lavaert, Marieke; Van der Meulen, Joni; Velghe, Imke; De Medts, Jelle; Weening, Karin; Roels, Juliette; De Mulder, Katrien; Volders, Pieter-Jan; De Preter, Katleen; Kerre, Tessa; Vandekerckhove, Bart; Leclercq, Georges; Vandesompele, Jo; Mestdagh, Pieter; Van Vlierberghe, Pieter; Speleman, Frank; Taghon, Tom
err分享
err收藏
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
errSCIENTIFIC REPORTS
IF3.9
err2020-01-14
err20
errOAAI
errMus, Liselot M.; Lambertz, Irina; Claeys, Shana; Kumps, Candy; Van Loocke, Wouter; Van Neste, Christophe; Umapathy, Ganesh; Vaapil, Marica; Bartenhagen, Christoph; Laureys, Genevieve; De Wever, Olivier; Bexell, Daniel; Fischer, Matthias; Hallberg, Bengt; Schulte, Johannes; De Wilde, Bram; Durinck, Kaat; Denecker, Geertrui; De Preter, Katleen; Speleman, Frank
err分享
err收藏

研究方向

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