Ashley M. Buckle - Publications, H-index & Citations

Ashley M. Buckle

biomedicine discovery institute and department of biochemistry and molecular biology

50H指数

240论文数

9.7K被引数

收录论文 76

发表时间

Prostate cancer risk-associated single-nucleotide polymorphisms impact the conformational dynamics of prostate-specific antigen 前列腺癌风险相关单核苷酸多态性影响前列腺特异性抗原的构象动力学

BMC Biology

IF4.5

2025-12-17

OAAI

Srilakshmi Srinivasan; Brooke K. Hayes; Mauricio G. S. Costa; Blake T. Riley; Emily Wilson; Emilia M. Marijanovic; Itamar Kass; Hannu Koistinen; David E. Hoke; Judith Clements; Ashley M. Buckle; Jyotsna Batra

Allosteric Anti-KLK4 Antibody Development for Targeted Anti-cancer Effects in Ovarian Carcinoma 别构抗KLK4抗体开发用于卵巢癌靶向抗肿瘤效应

Journal of Molecular Biology

IF4.5

2025-03-26

PREAI

Nikolaos A. Afratis; Blake T. Riley; Peter G. Chandler; Ashley M. Buckle; Irit Sagi

Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity

THYROID

IF6.7

2024-05-01

PREAI

Iwasaki, Hajime; Suwanai, Hirotsugu; Yakou, Fumiyoshi; Sakai, Hiroyuki; Ishii, Keitaro; Hara, Natsuko; Buckle, Ashley M.; Kanekura, Kohsuke; Miyagi, Tamami; Narumi, Satoshi; Suzuki, Ryo

Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2023-06-09

OAAI

Bai, Xiyuan; Schountz, Tony; Buckle, Ashley M.; Talbert, Janet L.; Sandhaus, Robert A.; Chan, Edward D.

α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages

JOURNAL OF IMMUNOLOGY

IF3.4

2022-11-01

OAAI

Bai, Xiyuan; Bai, An; Tomasicchio, Michele; Hagman, James R.; Buckle, Ashley M.; Gupta, Arnav; Kadiyala, Vineela; Bevers, Shaun; Serban, Karina A.; Kim, Kevin; Feng, Zhihong; Spendier, Kathrin; Hagen, Guy; Fornis, Lorelenn; Griffith, David E.; Dzieciatkowska, Monika; Sandhaus, Robert A.; Gerber, Anthony N.; Chan, Edward D.

A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-07-01

OAAI

Webb, Chaille T.; Yang, Wei; Riley, Blake T.; Hayes, Brooke K.; Sivaraman, Komagal Kannan; Malcolm, Tess R.; Harrop, Stephen; Atkinson, Sarah C.; Kass, Itamar; Buckle, Ashley M.; Drinkwater, Nyssa; McGowan, Sheena

Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19 (vol 12, 5207, 2022)

SCIENTIFIC REPORTS

IF3.9

2022-04-19

OAAI

Bai, Xiyuan; Buckle, Ashley M.; Vladar, Eszter K.; Janoff, Edward N.; Khare, Reeti; Ordway, Diane; Beckham, David; Fornis, Lorelenn B.; Majluf-Cruz, Abraham; Fugit, Randolph V.; Freed, Brian M.; Kim, Soohyun; Sandhaus, Robert A.; Chan, Edward D.

Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

SCIENTIFIC REPORTS

IF3.9

2022-03-25

OAAI

Bai, Xiyuan; Buckle, Ashley M.; Vladar, Eszter K.; Janoff, Edward N.; Khare, Reeti; Ordway, Diane; Beckham, David; Fornis, Lorelenn B.; Majluf-Cruz, Abraham; Fugit, Randolph, V; Freed, Brian M.; Kim, Soohyun; Sandhaus, Robert A.; Chan, Edward D.

Polymer End Group Control through a Decarboxylative Cobalt-Mediated Radical Polymerization: New Avenues for Synthesizing Peptide, Protein, and Nanomaterial Conjugates

JACS AU

IF8.7

2021-11-30

OAAI

Ayurini, Meri; Chandler, Peter G.; O'Leary, Paul D.; Wang, Ruoxin; Rudd, David; Milewska, Karen D.; Malins, Lara R.; Buckle, Ashley M.; Hooper, Joel F.

Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen

BIOCHEMICAL JOURNAL

IF4.3

2021-09-14

OAAI

Crowther, Jennifer M.; Gilmour, Letitia H.; Porebski, Benjamin T.; Heath, Sarah G.; Pattinson, Neil R.; Owen, Maurice C.; Fredericks, Rayleen; Buckle, Ashley M.; Fee, Conan J.; Gobl, Christoph; Dobson, Renwick C. J.

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily Serpin超家族的全面系统发育分析

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2021-03-21

OAAI

Spence, Matthew A.; Mortimer, Matthew D.; Buckle, Ashley M.; Minh, Bui Quang; Jackson, Colin J.

Mutational and biophysical robustness in a prestabilized monobody

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Chandler, Peter G.; Tan, Li Lynn; Porebski, Benjamin T.; Green, James S.; Riley, Blake T.; Broendum, Sebastian S.; Hoke, David E.; Falconer, Robert J.; Munro, Trent P.; Buckle, Malcolm; Jackson, Colin J.; Buckle, Ashley M.

Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-08-27

OAAI

Burnett, Deborah L.; Schofield, Peter; Langley, David B.; Jackson, Jennifer; Bourne, Katherine; Wilson, Emily; Porebski, Benjamin T.; Buckle, Ashley M.; Brink, Robert; Goodnow, Christopher C.; Christ, Daniel

Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

CELLS

IF5.2

2020-03-04

OAAI

Chandler, Peter G.; Buckle, Ashley M.

Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease

ENDOCRINOLOGY

IF3.3

2020-02-05

OAAI

Williams, Daniel E.; Le, Sarah N.; Hoke, David E.; Chandler, Peter G.; Gora, Monika; Godlewska, Marlena; Banga, J. Paul; Buckle, Ashley M.

Ribosome Evolution and Structural Capacitance

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2019-11-14

OAAI

Buckle, Ashley M.; Buckle, Malcolm

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

NATURE IMMUNOLOGY

IF27.6

2019-09-18

PREAI

Zammit, Nathan W.; Siggs, Owen M.; Gray, Paul E.; Horikawa, Keisuke; Langley, David B.; Walters, Stacey N.; Daley, Stephen R.; Loetsch, Claudia; Warren, Joanna; Yap, Jin Yan; Cultrone, Daniele; Russell, Amanda; Malle, Elisabeth K.; Villanueva, Jeanette E.; Cowley, Mark J.; Gayevskiy, Velimir; Dinger, Marcel E.; Brink, Robert; Zahra, David; Chaudhri, Geeta; Karupiah, Gunasegaran; Whittle, Belinda; Roots, Carla; Bertram, Edward; Yamada, Michiko; Jeelall, Yogesh; Enders, Anselm; Clifton, Benjamin E.; Mabbitt, Peter D.; Jackson, Colin J.; Watson, Susan R.; Jenne, Craig N.; Lanier, Lewis L.; Wiltshire, Tim; Spitzer, Matthew H.; Nolan, Garry P.; Schmitz, Frank; Aderem, Alan; Porebski, Benjamin T.; Buckle, Ashley M.; Abbott, Derek W.; Ziegler, John B.; Craig, Maria E.; Benitez-Aguirre, Paul; Teo, Juliana; Tangye, Stuart G.; King, Cecile; Wong, Melanie; Cox, Murray P.; Phung, Wilson; Tang, Jia; Sandoval, Wendy; Wertz, Ingrid E.; Christ, Daniel; Goodnow, Christopher C.; Grey, Shane T.

The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome

SCIENTIFIC REPORTS

IF3.9

2019-07-19

OAAI

Fodor, James; Riley, Blake T.; Kass, Itamar; Buckle, Ashley M.; Borg, Natalie A.

Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments

ANALYTICAL CHEMISTRY

IF6.7

2019-05-22

PREAI

Islam, Jiaul; Riley, Blake T.; Fercher, Christian; Jones, Martina L.; Buckle, Ashley M.; Howard, Christopher B.; Cox, Rosalind P.; Bell, Toby D. M.; Mahler, Stephen; Corrie, Simon R.

Protein engineering: the potential of remote mutations

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2019-03-22

OAAI

Wilding, Matthew; Hong, Nansook; Spence, Matthew; Buckle, Ashley M.; Jackson, Colin J.

研究方向