Christopher C. Goodnow

Garvan Institute of Medical Research

H指数:104

被引数:4.4万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function

白细胞中人E3泛素连接酶CBL的体细胞缺陷会损害b细胞，但不会损害T细胞的发育和功能

Nature Immunology

IF27.6

2026-01-150

OAAI

Taja Vatovec; Anna-Lena Neehus; Katherine J. L. Jackson; Danielle T. Avery; Ivan Bagarić; Lucia Erazo; Carlos A. Arango-Franco; Masato Ogishi; Syed F. Ahmed; Axel Cederholm; Amanda J. Russell; Erika Della Mina; Dena Al-Rifai; Rowena Bull; Lori Buetow; Steicy Sobrino; Allison Zhang; Lara Wahlster; Marine Michelet; Nima Parvaneh; Jessica Peel; Federica Barzaghi; Davide Leardini; Quentin Philippot; Francesco Saettini; Jacques Dutrieux; Benedicte de Muylder; Francesca Vendemini; Francesco Baccelli; Albert Catala; Eleonora Gambineri; Marinella Veltroni; Vignesh Pandiarajan; Yurena Aguilar; Filomeen Haerynck; Michael Elliott; Stuart Turville; Fabienne Brillot; Taushif Khan; Filippo Consonni; Laureline Berteloot; William A. Sewell; Geetha Rao; Laetitia Largeaud; Francesca Conti; Cecile Roullion; Cécile Masson; Francesco Pegoraro; Tianyi Ye; Samantha Joubran; Emily Villalpando; Boris Bessot; Yoann Seeleuthner; Tom Le Voyer; Jérémie Rosain; Hailun Li; Zarah Janda; Edoardo Muratore; Camille Soudée; Eric Delabesse; Claire Goulvestre; Mohammad Shahrooei; Anne Puel; Isabelle André; Christine Bole-Feysot; Laurent Abel; Miriam Erlacher; Vivien Béziat; Chantal Lagresle-Peyrou; Remi Cheynier; Emmanuelle Six; Nico Marr; Marlène Pasquet; Laia Alsina; Christopher C. Goodnow; Nils Landegren; Alessandro Aiuti; Peng Zhang; Riccardo Masetti; Danny T. Huang; Cindy S. Ma; Jean-Laurent Casanova; Vijay G. Sankaran; Jacinta Bustamante; Stuart G. Tangye; Jonathan Bohlen

Humoral epitope dominance and immune imprinting by SARS-CoV-1 and SARS-CoV-2 vaccines

SARS-CoV-1和SARS-CoV-2疫苗诱导的体液表位优势和免疫印迹

Immunology and Cell Biology

IF3

2026-01-010

OAAI

A transcriptomic signature of self-reactivity in the germinal center

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-010

PRE

Refractory coeliac disease or something else?

难治性乳糜泻还是其他情况？

Pathology

IF5.2

2025-10-100

PRE

Lymphoma driver mutations at the root of somatic evolution of nerve-damaging autoantibodies in myelin associated glycoprotein neuropathy

髓鞘相关糖蛋白神经病变中，导致损伤神经自身抗体体细胞进化的淋巴瘤驱动突变。

Journal of Autoimmunity

IF7

2025-09-060

OAAI

A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease

一种体细胞诱变的三联因素在自身反应性B细胞中汇聚，导致病毒诱导的自身免疫性疾病。

IMMUNITY

IF26.3

2025-02-010

OAAI

The CD8+T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

IMMUNITY

IF26.3

2024-06-012

PRE

EVIDENCE FOR SOMATIC MUTATION IN LYMPHOMA DRIVER GENES AT THE ROOT OF CLONAL EVOLUTION OF PATHOGENIC AUTOANTIBODIES IN MAG NEUROPATHY

髓鞘碱性蛋白神经病变中致病性自身抗体克隆进化的根源处，淋巴瘤驱动基因体细胞突变的证据

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2024-06-010

PRE

Helper T cell immunity in humans with inherited CD4 deficiency

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-04-013

OAAI

Guerin, Antoine; Moncada-Velez, Marcela; Jackson, Katherine; Ogishi, Masato; Rosain, Jeremie; Mancini, Mathieu; Langlais, David; Nunez, Andrea; Webster, Samantha; Goyette, Jesse; Khan, Taushif; Marr, Nico; Avery, Danielle T.; Rao, Geetha; Waterboer, Tim; Michels, Birgitta; Neves, Esmeralda; Morais, Catia Iracema; London, Jonathan; Mestrallet, Stephanie; Maire, Pierre Quartier Dit; Neven, Benedicte; Rapaport, Franck; Seeleuthner, Yoann; Lev, Atar; Simon, Amos J.; Montoya, Jorge; Barel, Ortal; Gomez-Rodriguez, Julio; Orrego, Julio C.; L'Honneur, Anne-Sophie; Soudee, Camille; Rojas, Jessica; Velez, Alejandra C.; Sereti, Irini; Terrier, Benjamin; Marin, Nancy; Garcia, Luis F.; Abel, Laurent; Boisson-Dupuis, Stephanie; Reis, Joel; Marinho, Antonio; Lisco, Andrea; Faria, Emilia; Goodnow, Christopher C.; Vasconcelos, Julia; Beziat, Vivien; Ma, Cindy S.; Somech, Raz; Casanova, Jean-Laurent; Bustamante, Jacinta; Franco, Jose Luis; Tangye, Stuart G.

A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome

AICDA中的一种新的杂合变体会损害人b细胞中的Ig类别转换和体细胞超突变，并与常染色体显性HIGM2综合征相关

JOURNAL OF CLINICAL IMMUNOLOGY

IF5.7

2024-02-160

OAAI

DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection

DOCK2缺乏导致抗病毒T细胞反应缺陷和单纯疱疹病毒感染的控制受损

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2024-02-152

OAAI

Isolation and characterisation of PR3-specific B cells and their immunoglobulin sequences

JOURNAL OF AUTOIMMUNITY

IF7

2024-01-010

Germline mutations in a G protein identify signaling cross-talk in T cells

G蛋白配体生殖系突变确定了T细胞中的信号交叉对话

Science

IF45.8

2024-01-010

Hyoungjun Ham; Huie Jing; Ian T. Lamborn; Megan M. Kober; Alexey Koval; Yamina A. Berchiche; David Eric Anderson; Kirk M. Druey; Judith N. Mandl; Bertrand Isidor; Carlos R. Ferreira; Alexandra F. Freeman; Sundar Ganesan; Meliha Karsak; Peter Mustillo; Juliana Teo; Zarazuela Zolkipli‐Cunningham; Nicolas Chatron; François Lecoquierre; Andrew J. Oler; Jana Pachlopnik Schmid; Douglas Byron Kuhns; Xuehua Xu; Fabian H. Hauck; Waleed Al–Herz; Matias Wagner; Paulien A. Terhal; Mari Muurinen; Vincent Barlogis; Phillip Cruz; Jeffrey J. Danielson; Helen Stewart; Petra Loid; Sebastian Rading; Boris Keren; Rolph Pfundt; Kol A. Zarember; Katharina Vill; Lorraine Potocki; Kenneth N. Olivier; Gaëtan Lesca; Laurence Olivier Faivre; Melanie Wong; Anne Puel; Janet S. Chou; Maud Tusseau; Niki Maria Moutsopoulos; Helen F Matthews; Cas Simons; Ryan J. Taft; Ariane G. Soldatos; Etienne Masle‐Farquhar; Stefania Pittaluga; Robert Adrian Brink; Danielle L. Fink; Heidi H. Kong; Juraj Kabát; Woo Sung Kim; Tatjana Bierhals; Kazuyuki Meguro; Amy P. Hsu; Jingwen Gu; Jennifer L. Stoddard; Benito Baños-Piñero; Maria A. Slack; Giampaolo Trivellin; Benoît Mazel; Maarja Soomann; Samuel T. Li; Val J. Watts; Constantine A. Stratakis; Maria F. Rodriguez-Quevedo; Ange‐Line Bruel; Marita Lipsanen‐Nyman; Paul Saultier; Rashmi Jain; Daphné Lehalle; Daniel Torres; Kathleen E. Sullivan; S. Barbarot; Axel Dietmar Neu; Yannis Duffourd; Morgan N. Similuk; Kirsty M. McWalter; Pierre Blanc; Stéphane Bezieau; Tian Jin; Raif S. Geha; Jean‐Laurent Casanova; Outi Mäkitie; Christian Kubisch; Patrick Edery; John Christodoulou; Ronald N. Germain; Christopher Carl Goodnow; Thomas P. Sakmar; Daniel D. Billadeau; Sébastien Küry; Vladimir L. Katanaev; Yu Zhang; Michael J. Lenardo; Helen C. Su

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

具有替代性nf-κb途径缺陷的人类针对I型ifn的自身抗体

Nature

IF48.5

2023-11-080

OAAI

Tom Le Voyer; Audrey V. Parent; Xian Liu; Axel Cederholm; Adrian Gervais; Jérémie Rosain; Tina Nguyen; Malena Perez Lorenzo; Elze Rackaityte; Darawan Rinchai; Peng Zhang; Lucy Bizien; Gonca Hancioglu; Pascale Ghillani-Dalbin; Jean-Luc Charuel; Quentin Philippot; Mame Sokhna Gueye; Majistor Raj Luxman Maglorius Renkilaraj; Masato Ogishi; Camille Soudée; Mélanie Migaud; Flore Rozenberg; Mana Momenilandi; Quentin Riller; Luisa Imberti; Ottavia M. Delmonte; Gabriele Müller; Baerbel Keller; Julio Orrego; William Alexander Franco Gallego; Tamar Rubin; Melike Emiroglu; Nima Parvaneh; Daniel Eriksson; Maribel Aranda-Guillen; David I. Berrios; Linda Vong; Constance H. Katelaris; Peter Mustillo; Johannes Raedler; Jonathan Bohlen; Jale Bengi Celik; Camila Astudillo; Sarah Winter; Catriona McLean; Aurélien Guffroy; Joseph L. DeRisi; David Yu; Corey Miller; Yi Feng; Audrey Guichard; Vivien Béziat; Jacinta Bustamante; Qiang Pan-Hammarström; Yu Zhang; Lindsey B. Rosen; Steve M. Holland; Marita Bosticardo; Heather Kenney; Riccardo Castagnoli; Charlotte A. Slade; Kaan Boztuğ; Nizar Mahlaoui; Sylvain Latour; Roshini S. Abraham; Vassilios Lougaris; Fabian Hauck; Anna Sediva; Faranaz Atschekzei; Georgios Sogkas; M. Cecilia Poli; Mary A. Slatter; Boaz Palterer; Michael D. Keller; Alberto Pinzon-Charry; Anna Sullivan; Luke Droney; Daniel Suan; Melanie Wong; Alisa Kane; Hannah Hu; Cindy Ma; Hana Grombiříková; Peter Ciznar; Ilan Dalal; Nathalie Aladjidi; Miguel Hie; Estibaliz Lazaro; Jose Franco; Sevgi Keles; Marion Malphettes; Marlene Pasquet; Maria Elena Maccari; Andrea Meinhardt; Aydan Ikinciogullari; Mohammad Shahrooei; Fatih Celmeli; Patrick Frosk; Christopher C. Goodnow; Paul E. Gray; Alexandre Belot; Hye Sun Kuehn; Sergio D. Rosenzweig; Makoto Miyara; Francesco Licciardi; Amélie Servettaz; Vincent Barlogis; Guillaume Le Guenno; Vera-Maria Herrmann; Taco Kuijpers; Grégoire Ducoux; Françoise Sarrot-Reynauld; Catharina Schuetz; Charlotte Cunningham-Rundles; Frédéric Rieux-Laucat; Stuart G. Tangye; Cristina Sobacchi; Rainer Doffinger; Klaus Warnatz; Bodo Grimbacher; Claire Fieschi; Laureline Berteloot; Vanessa L. Bryant; Sophie Trouillet Assant; Helen Su; Benedicte Neven; Laurent Abel; Qian Zhang; Bertrand Boisson; Aurélie Cobat; Emmanuelle Jouanguy; Olle Kampe; Paul Bastard; Chaim M. Roifman; Nils Landegren; Luigi D. Notarangelo; Mark S. Anderson; Jean-Laurent Casanova; Anne Puel

Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy

MOLECULAR THERAPY

IF12

2023-07-0113

OAAI

Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL

网络分析揭示了14q32簇mirna在确定IGHV突变和未突变CLL之间的转录差异中的主要作用

LEUKEMIA

IF13.4

2023-05-111

OAAI

CARD11 gain-of-function mutation drives cell-autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-03-077

OAAI

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

通过基于表位的选择从恢复期患者中广泛中和SARS-CoV-2抗体

NATURE COMMUNICATIONS

IF15.7

2023-02-0819

OAAI

Rouet, Romain; Henry, Jake Y.; Johansen, Matt D.; Sobti, Meghna; Balachandran, Harikrishnan; Langley, David B.; Walker, Gregory J.; Lenthall, Helen; Jackson, Jennifer; Ubiparipovic, Stephanie; Mazigi, Ohan; Schofield, Peter; Burnett, Deborah L.; Brown, Simon H. J.; Martinello, Marianne; Hudson, Bernard; Gilroy, Nicole; Post, Jeffrey J.; Kelleher, Anthony; Jaeck, Hans-Martin; Goodnow, Christopher C.; Turville, Stuart G.; Rawlinson, William D.; Bull, Rowena A.; Stewart, Alastair G.; Hansbro, Philip M.; Christ, Daniel

STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+T cell dysregulation and accumulation

STAT3功能获得性突变通过病理性NKG2Dhi CD8 T细胞失调和积累将白血病与自身免疫性疾病联系起来

IMMUNITY

IF26.3

2022-12-0130

OAAI

Masle-Farquhar, Etienne; Jackson, Katherine J. L.; Peters, Timothy J.; Al-Eryani, Ghamdan; Singh, Mandeep; Payne, Kathryn J.; Rao, Geetha; Avery, Danielle T.; Apps, Gabrielle; Kingham, Jennifer; Jara, Christopher J.; Skvortsova, Ksenia; Swarbrick, Alexander; Ma, Cindy S.; Suan, Daniel; Uzel, Gulbu; Chua, Ignatius; Leiding, Jennifer W.; Heiskanen, Kaarina; Preece, Kahn; Kainulainen, Leena; O'Sullivan, Michael; Cooper, Megan A.; Seppaeuronen, Mikko R. J.; Mustjoki, Satu; Brothers, Shannon; Vogel, Tiphanie P.; Brink, Robert; Tangye, Stuart G.; Reed, Joanne H.; Goodnow, Christopher C.

STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2022-10-0126

PRE

Pelham, Simon J.; Caldirola, Maria Soledad; Avery, Danielle T.; Mackie, Joseph; Rao, Geetha; Gothe, Florian; Peters, Timothy J.; Guerin, Antoine; Neumann, David; Vokurkova, Doris; Hwa, Vivian; Zhang, Wenming; Lyu, Shu-Chen; Chang, Iris; Manohar, Monali; Nadeau, Kari C.; Gaillard, Maria Isabel; Bezrodnik, Liliana; Iotova, Violeta; Zwirner, Norberto Walter; Gutierrez, Mavel; Al-Herz, Waleed; Goodnow, Christopher C.; Vargas-Hernandez, Alexander; Satter, Lisa R. Forbes; Hambleton, Sophie; Deenick, Elissa K.; Ma, Cindy S.; Tangye, Stuart G.

Christopher C. Goodnow

个人简介

教育背景

工作经历

荣誉奖项

研究方向