Gunnar F. Schröder - Publications, H-index & Citations

Gunnar F. Schröder

forschungszentrum juelich

49H指数

168论文数

1.1W被引数

收录论文 67

发表时间

Stochastic misfolding drives the emergence of distinct α-synuclein strains 随机错误折叠驱动不同α-突触核蛋白菌株的出现

Neuron

IF15

2026-02-27

PREAI

Raphaella W.L. So; Benedikt Frieg; José D. Camino; Christopher Situ; Mark N. Metri; Nicholas R.G. Silver; Le yao Li; Alison Mao; Erica Stuart; Gunnar F. Schröder; Joel C. Watts

Cryo-EM studies of amyloid-β fibrils from human and murine brains carrying the Uppsala APP mutation (Δ690–695)携带Uppsala APP突变（Δ690–695）的人和小鼠脑源淀粉样蛋白-β纤维的冷冻电子显微镜研究

Acta Neuropathologica Communications

IF5.7

2025-10-04

OAAI

Mara Zielinski; Fernanda S. Peralta Reyes; Lothar Gremer; Simon Sommerhage; María Pagnon de la Vega; Christine Röder; Thomas V. Heidler; Stina Syvänen; Dieter Willbold; Dag Sehlin; Martin Ingelsson; Gunnar F. Schröder

Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation Anle138b主要结合到类脂性Aβ₄₀原纤维的中央空腔，并调节原纤维的形成

Nature Communications

IF15.7

2025-10-03

OAAI

Mookyoung Han; Benedikt Frieg; Dirk Matthes; Andrei Leonov; Sergey Ryazanov; Karin Giller; Evgeny Nimerovsky; Marianna Stampolaki; Kai Xue; Kerstin Overkamp; Christian Dienemann; Dietmar Riedel; Armin Giese; Stefan Becker; Bert L. de Groot; Gunnar F. Schröder; Loren B. Andreas; Christian Griesinger

Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis 基于物理和深度学习的蛋白质工程滤器的解析：一项关于用于工业底物水解的脂肪酶的案例研究

PLOS ONE

IF2.6

2025-09-12

OAAI

Gardiner, Spencer; Dollinger, Peter; Kovacic, Filip; Pietruszka, Jorg; Ess, Daniel H.; Jaeger, Karl-Erich; Schroeder, Gunnar F.; Della Corte, Dennis

Capturing G protein-coupled receptors into native lipid-bilayer nanodiscs using new diisobutylene/maleic acid (DIBMA) copolymers 利用新型二异丁烯/马来酸（DIBMA）共聚物将G蛋白偶联受体捕获到天然脂质双分子层纳米盘中

Methods

IF4.3

2025-09-04

OAAI

Ci Chu; Carolyn Vargas; Maria Carolina Barbosa; Simon Sommerhage; Gerald N. Rechberger; David Pahovnik; Ema Žagar; Gunnar F. Schröder; Sandro Keller; Manuel Etzkorn

Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge

NATURE METHODS

IF32.1

2024-06-25

OAAI

Lawson, Catherine L.; Kryshtafovych, Andriy; Pintilie, Grigore D.; Burley, Stephen K.; Cerny, Jiri; Chen, Vincent B.; Emsley, Paul; Gobbi, Alberto; Joachimiak, Andrzej; Noreng, Sigrid; Prisant, Michael G.; Read, Randy J.; Richardson, Jane S.; Rohou, Alexis L.; Schneider, Bohdan; Sellers, Benjamin D.; Shao, Chenghua; Sourial, Elizabeth; Williams, Chris I.; Williams, Christopher J.; Yang, Ying; Abbaraju, Venkat; Afonine, Pavel V.; Baker, Matthew L.; Bond, Paul S.; Blundell, Tom L.; Burnley, Tom; Campbell, Arthur; Cao, Renzhi; Cheng, Jianlin; Chojnowski, Grzegorz; Cowtan, K. D.; DiMaio, Frank; Esmaeeli, Reza; Giri, Nabin; Grubmueller, Helmut; Hoh, Soon Wen; Hou, Jie; Hryc, Corey F.; Hunte, Carola; Igaev, Maxim; Joseph, Agnel P.; Kao, Wei-Chun; Kihara, Daisuke; Kumar, Dilip; Lang, Lijun; Lin, Sean; Subramaniya, Sai R. Maddhuri Venkata; Mittal, Sumit; Mondal, Arup; Moriarty, Nigel W.; Muenks, Andrew; Murshudov, Garib N.; Nicholls, Robert A.; Olek, Mateusz; Palmer, Colin M.; Perez, Alberto; Pohjolainen, Emmi; Pothula, Karunakar R.; Rowley, Christopher N.; Sarkar, Daipayan; Schaefer, Luisa U.; Schlicksup, Christopher J.; Schroeder, Gunnar F.; Shekhar, Mrinal; Si, Dong; Singharoy, Abhishek; Sobolev, Oleg V.; Terashi, Genki; Vaiana, Andrea C.; Vedithi, Sundeep C.; Verburgt, Jacob; Wang, Xiao; Warshamanage, Rangana; Winn, Martyn D.; Weyand, Simone; Yamashita, Keitaro; Zhao, Minglei; Schmid, Michael F.; Berman, Helen M.; Chiu, Wah

Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease

BRAIN

IF11.7

2024-03-01

OAAI

Pesch, Verena; Flores-Fernandez, Jose Miguel; Reithofer, Sara; Ma, Liang; Oezduezenciler, Pelin; Busch, Yannick; Sriraman, Aishwarya; Wang, YongLiang; Amidian, Sara; Kroepel, Chiara V. M.; Mueller, Laura; Lien, Yi; Rudtke, Olivia; Frieg, Benedikt; Schroeder, Gunnar F.; Wille, Holger; Tamgueney, Gueltekin

Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)

NATURE COMMUNICATIONS

IF15.7

2024-02-13

OAAI

Frieg, Benedikt; Han, Mookyoung; Giller, Karin; Dienemann, Christian; Riedel, Dietmar; Becker, Stefan; Andreas, Loren B.; Griesinger, Christian; Schroeder, Gunnar F.

The 3D structure of lipidic fibrils of α-synuclein

NATURE COMMUNICATIONS

IF15.7

2022-11-10

OAAI

Frieg, Benedikt; Antonschmidt, Leif; Dienemann, Christian; Geraets, James A.; Najbauer, Eszter E.; Matthes, Dirk; de Groot, Bert L.; Andreas, Loren B.; Becker, Stefan; Griesinger, Christian; Schroeder, Gunnar F.

Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein

COMMUNICATIONS BIOLOGY

IF5.1

2022-09-30

OAAI

Frieg, Benedikt; Geraets, James A.; Strohaeker, Timo; Dienemann, Christian; Mavroeidi, Panagiota; Jung, Byung Chul; Kim, Woojin S.; Lee, Seung-Jae; Xilouri, Maria; Zweckstetter, Markus; Schroeder, Gunnar F.

Molecular interactions of FG nucleoporin repeats at high resolution

NATURE CHEMISTRY

IF20.2

2022-09-22

OAAI

de Opakua, Alain Ibanez; Geraets, James A.; Frieg, Benedikt; Dienemann, Christian; Savastano, Adriana; Rankovic, Marija; Cima-Omori, Maria-Sol; Schroeder, Gunnar F.; Zweckstetter, Markus

The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils

NATURE COMMUNICATIONS

IF15.7

2022-09-14

OAAI

Antonschmidt, Leif; Matthes, Dirk; Dervisoglu, Riza; Frieg, Benedikt; Dienemann, Christian; Leonov, Andrei; Nimerovsky, Evgeny; Sant, Vrinda; Ryazanov, Sergey; Giese, Armin; Schroeder, Gunnar F.; Becker, Stefan; de Groot, Bert L.; Griesinger, Christian; Andreas, Loren B.

Major tail proteins of bacteriophages of the order Caudovirales

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-01-01

OAAI

Zinke, Maximilian; Schroeder, Gunnar F.; Lange, Adam

Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses

TRANSLATIONAL PSYCHIATRY

IF6.2

2021-12-17

OAAI

Cukkemane, Abhishek; Becker, Nina; Zielinski, Mara; Frieg, Benedikt; Lakomek, Nils-Alexander; Heise, Henrike; Schroeder, Gunnar F.; Willbold, Dieter; Weiergraeber, Oliver H.

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-08-11

OAAI

de la Vega, Maria Pagnon; Giedraitis, Vilmantas; Michno, Wojciech; Kilander, Lena; Guener, Goekhan; Zielinski, Mara; Lowenmark, Malin; Brundin, RoseMarie; Danfors, Torsten; Soderberg, Linda; Alafuzoff, Irina; Nilsson, Lars N. G.; Erlandsson, Anna; Willbold, Dieter; Mueller, Stephan A.; Schroeder, Gunnar F.; Hanrieder, Jorg; Lichtenthaler, Stefan F.; Lannfelt, Lars; Sehlin, Dag; Ingelsson, Martin

Challenges in sample preparation and structure determination of amyloids by cryo-EM

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-08-01

OAAI

Zielinski, Mara; Roeder, Christine; Schroeder, Gunnar F.

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting 内溶酶体a β 浓度和pH触发a β 寡聚体的形成，从而有效诱导Tau错误分选

NATURE COMMUNICATIONS

IF15.7

2021-07-30

OAAI

Schutzmann, Marie P.; Hasecke, Filip; Bachmann, Sarah; Zielinski, Mara; Haensch, Sebastian; Schroeder, Gunnar F.; Zempel, Hans; Hoyer, Wolfgang

Clustering polymorphs of tau and IAPP fibrils with the CHEP algorithm

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

IF4.5

2021-03-01

PREAI

Pothula, Karunakar R.; Geraets, James A.; Ferber, Inda I.; Schroeder, Gunnar F.

Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge

NATURE METHODS

IF32.1

2021-02-04

OAAI

Lawson, Catherine L.; Kryshtafovych, Andriy; Adams, Paul D.; Afonine, Pavel, V; Baker, Matthew L.; Barad, Benjamin A.; Bond, Paul; Burnley, Tom; Cao, Renzhi; Cheng, Jianlin; Chojnowski, Grzegorz; Cowtan, Kevin; Dill, Ken A.; DiMaio, Frank; Farrell, Daniel P.; Fraser, James S.; Herzik, Mark A., Jr.; Hoh, Soon Wen; Hou, Jie; Hung, Li-Wei; Igaev, Maxim; Joseph, Agnel P.; Kihara, Daisuke; Kumar, Dilip; Mittal, Sumit; Monastyrskyy, Bohdan; Olek, Mateusz; Palmer, Colin M.; Patwardhan, Ardan; Perez, Alberto; Pfab, Jonas; Pintilie, Grigore D.; Richardson, Jane S.; Rosenthal, Peter B.; Sarkar, Daipayan; Schafer, Luisa U.; Schmid, Michael F.; Schroder, Gunnar F.; Shekhar, Mrinal; Si, Dong; Singharoy, Abishek; Terashi, Genki; Terwilliger, Thomas C.; Vaiana, Andrea; Wang, Liguo; Wang, Zhe; Wankowicz, Stephanie A.; Williams, Christopher J.; Winn, Martyn; Wu, Tianqi; Yu, Xiaodi; Zhang, Kaiming; Berman, Helen M.; Chiu, Wah

Architecture of the flexible tail tube of bacteriophage SPP1

NATURE COMMUNICATIONS

IF15.7

2020-11-13

OAAI

Zinke, Maximilian; Sachowsky, Katrin A. A.; Oester, Carl; Zinn-Justin, Sophie; Ravelli, Raimond; Schroeder, Gunnar F.; Habeck, Michael; Lange, Adam

研究方向