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P

Philip J. Day

astex pharmaceuticals

56H指数
242论文数
1.1W被引数
收录论文 64
发表时间
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From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design从KRASG12D到泛KRAS抑制剂─一项由合成创新和基于结构的药物设计所推动的旅程
errJournal of Medicinal Chemistry
IF6.8
err2026-04-09
err0
PREAI
errXiaoshen Ma; David L. Sloman; Timothy J. Henderson; D. Jonathan Bennett; Gianni Chessari; Philip J. Day; Ruchia Duggal; Emma Edelstein; Symon Gathiaka; Andrew Hoover; Steven Howard; Shuhei Kawamura; Yu Kobayakawa; Brian M. Lacey; Thomas W. Lyons; My S. Mansueto; Richard Miller; Shinji Mizuarai; Erik V. Munsell; Marc O’Reilly; Tsuyoshi Oshima; Ryan D. Otte; Anandan Palani; David C. Rees; Takeshi Sagara; Aaron Sather; Patrick Schopf; Kazuaki Shibata; Yuki Shikata; Nicolas Solban; Sriraman Venkataraman; Dan Su; Uma Swaminathan; Yingchun Ye; Alexander Stoeck; Yongxin Han
err分享
err收藏
Exploring ethical; sustainable and effective foetal bovine serum alternatives for in vitro mammalian cell culture探索适用于体外哺乳动物细胞培养的符合伦理、可持续且有效的胎牛血清替代品
errFrontiers in Toxicology
IF4.6
err2026-03-12
err0
errOAAI
errHM Huiyuan Meng; PJ Philip J. R. Day
err分享
err收藏
Sensitising PDAC to Gemcitabine by Suppressing NF-κB Pathway and Enhancing Apoptosis
errPharmaceuticals
IF4.8
err2026-01-30
err0
errOAAI
errEnhui Jin; Maria Rita Gil da Silva Simões; Steve O’Hagan; Enzhi Jin; Philip J. Day
err分享
err收藏
Tunable Release of Ions from Graphene Oxide Laminates for Sustained Antibacterial Activity in a Biomimetic Environment (Small 28/2025)氧化石墨烯层合材料的可调离子释放以实现在仿生环境中的持续抗菌活性（Small 28/2025）
errSmall
IF12.1
err2025-07-18
err0
PREAI
errSwathi Suran; Negin Kamyar; Kun Huang; Farzad Foroutan; Premlal Balakrishna Pillai; Xuzhao Liu; John Vaughan; Darren Wilson; Philip J. Day; Rahul R. Nair
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err收藏
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2) (vol 67, pg 4655, 2024)基于片段的SH2结构域蛋白酪氨酸磷酸酶-2（SHP2）别构抑制剂的发现（vol 67, pg 4655, 2024）
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-05-08
err0
PREAI
errDay, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; Denis, Jeffrey D. St; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N.
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Phylogeny and virulence determinant detection of Fusobacterium necrophorum strains isolated at the UK Anaerobe Reference Unit between 1982 and 2019弗氏梭杆菌 (Fusobacterium necrophorum) 菌株的系统发育和毒力决定因子检测（1982年至2019年于英国厌氧菌参考单位分离）
errCLINICAL MICROBIOLOGY AND INFECTION
IF8.5
err2025-01-01
err0
PREAI
errPerry, Michael D.; Vranckx, Katleen; Copsey-Mawer, Sarah; Scotford, Selina; Anderson, Bethan; Day, Philip J.; Watkins, Joanne; Corden, Sally; Hughes, Harriet; Morris, Trefor E.
err分享
err收藏
Primary Sequence and Three-Dimensional Structural Comparison between Malanin and Ricin, a Type II Ribosome-Inactivating Protein
errTOXINS
IF4
err2024-10-13
err0
errOAAI
errYuan, Yan; Wu, Shuxiao; Day, Philip J. R.
err分享
err收藏
Use of Drug Sensitisers to Improve Therapeutic Index in Cancer
errPHARMACEUTICS
IF5.5
err2024-07-11
err2
errOAAI
errChen, Yu-Shan; Jin, Enhui; Day, Philip J.
err分享
err收藏
Tunable Release of Ions from Graphene Oxide Laminates for Sustained Antibacterial Activity in a Biomimetic Environment
errSMALL
IF12.1
err2024-04-30
err2
errOAAI
errSuran, Swathi; Kamyar, Negin; Huang, Kun; Foroutan, Farzad; Pillai, Premlal Balakrishna; Liu, Xuzhao; Vaughan, John; Wilson, Darren; Day, Philip J.; Nair, Rahul R.
err分享
err收藏
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-03-11
err3
PREAI
errDay, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; St. Denis, Jeffrey D.; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N.
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An Analysis of Mechanisms for Cellular Uptake of miRNAs to Enhance Drug Delivery and Efficacy in Cancer Chemoresistance
errnon coding rna research
IF3
err2021-04-16
err3
errOAAI
errGrixti, Justine M.; Ayers, Duncan; Day, Philip J. R.
err分享
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Viral Involvement in Alzheimer's Disease
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-03-09
err60
errOAAI
errSait, Ahmad; Angeli, Cristian; Doig, Andrew J.; Day, Philip J. R.
err分享
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An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines
errMETABOLOMICS
IF3.3
err2020-10-07
err30
errOAAI
errMuelas, Marina Wright; Roberts, Ivayla; Mughal, Farah; O'Hagan, Steve; Day, Philip J.; Kell, Douglas B.
err分享
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Fragment-based drug discovery to identify small molecule allosteric inhibitors of SHP2
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errDay, Philip J.; Berdini, Valerio; Castro, Juan; Chessari, Gianni; Davies, Thomas G.; Day, James E.; Fukaya, Satoshi; Hamlett, Chris; Hearn, Keisha; Hiscock, Steve; Holvey, Rhian; Ito, Satoru; Kodama, Yasuo; Matsuo, Kenichi; Nakatsuru, Yoko; Palmer, Nick; Price, Amanda; Shimamura, Tadashi; St Denis, Jeffrey D.; Wallis, Nicola G.; Williams, Glyn; Johnson, Christopher N.
err分享
err收藏
The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data基尼系数作为选择用于归一化表达谱数据的基尼基因的无偏工具的作用和稳健性
errSCIENTIFIC REPORTS
IF3.9
err2019-11-29
err28
errOAAI
errMuelas, Marina Wright; Mughal, Farah; O'Hagan, Steve; Day, Philip J.; Kell, Douglas B.
err分享
err收藏
Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli多个流入和流出转运蛋白参与大肠杆菌阳离子荧光染料的积累
errBMC MICROBIOLOGY
IF4.2
err2019-08-22
err30
errOAAI
errJindal, Srijan; Yang, Lei; Day, Philip J.; Kell, Douglas B.
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err收藏
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites神经退行性疾病靶标犬尿氨酸3-单加氧酶的脑渗透性抑制剂可防止神经毒性代谢产物的积累
errCOMMUNICATIONS BIOLOGY
IF5.1
err2019-07-24
err43
errOAAI
errZhang, Shaowei; Sakuma, Michiyo; Deora, Girdhar S.; Levy, Colin W.; Klausing, Alex; Breda, Carlo; Read, Kevin D.; Edlin, Chris D.; Ross, Benjamin P.; Muelas, Marina Wright; Day, Philip J.; O'Hagan, Stephen; Kell, Douglas B.; Schwarcz, Robert; Leys, David; Heyes, Derren J.; Giorgini, Flaviano; Scrutton, Nigel S.
err分享
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GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries
errACS SYNTHETIC BIOLOGY
IF3.9
err2019-05-27
err10
errOAAI
errCurrin, Andrew; Kwok, Jane; Sadler, Joanna C.; Bell, Elizabeth L.; Swainston, Neil; Ababi, Maria; Day, Philip; Turner, Nicholas J.; Kell, Douglas B.
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GeneGini: Assessment via the Gini Coefficient of Reference Housekeeping'' Genes and Diverse Human Transporter Expression Profiles
errCELL SYSTEMS
IF7.7
err2018-02-01
err54
errOAAI
errO'Hagan, Steve; Muelas, Marina Wright; Day, Philip J.; Lundberg, Emma; Kell, Douglas B.
err分享
err收藏
CodonGenie: optimised ambiguous codon design tools
errPEERJ COMPUTER SCIENCE
IF2.5
err2017-07-10
err9
errOAAI
errSwainston, Neil; Currin, Andrew; Green, Lucy; Breitling, Rainer; Day, Philip J.; Kell, Douglas B.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
R
Ralf Paus
H 指数: 128 · 论文数: 1.7K
D
Douglas B. Kell
H 指数: 121 · 论文数: 846
I
Irene Oi‐Lin Ng
H 指数: 110 · 论文数: 990
A
A. Manz
H 指数: 99 · 论文数: 566
J
Jo Vandesompele
H 指数: 96 · 论文数: 803
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