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Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin Hu, Li-Yen R.; Ackermann, Maegen A.; Hecker, Peter A.; Prosser, Benjamin L.; King, Brendan; O'Connell, Kelly A.; Grogan, Alyssa; Meyer, Logan C.; Berndsen, Christopher E.; Wright, Nathan T.; Lederer, W. Jonathan; Kontrogianni-Konstantopoulos, Aikaterini 分享 收藏
Small Obscurins at the Intercalated Disc Mediate Structure, Cell Size, and Adhesion Ackermann, Maegen; King, Brendan; Perry, Nicole; Rudloff, Michael; Berndsen, Christopher; Wright, Nathan; Hecker, Peter; Kontrogianni-Konstantopoulos, Aikaterini 分享 收藏
A Missense Mutation in the Obscurin Gene Leads to Hypertrophic Cardiomyopathy due to Deregulated Calcium Cycling Hu, Li-Yen R.; Ackermann, Maegen; Hecker, Peter; Prosser, Benjamin; King, Brendan; O'Connell, Kelly; Asico, Larry; Jose, Pedro; Wright, Nathan; Lederer, Jonathan; Kontrogianni-Konstantopoulos, Aikaterini 分享 收藏
Cardiac mitochondrial proteome dynamics with heavy water reveals stable rate of mitochondrial protein synthesis in heart failure despite decline in mitochondrial oxidative capacity Shekar, Kadambari Chandra; Li, Ling; Dabkowski, Erinne R.; Xu, Wenhong; Ribeiro, Rogerio Faustino, Jr.; Hecker, Peter A.; Recchia, Fabio A.; Sadygov, Rovshan G.; Willard, Belinda; Kasumov, Takhar; Stanley, William C. 分享 收藏
Docosahexaenoic Acid Supplementation Alters Key Properties of Cardiac Mitochondria and Modestly Attenuates Development of Left Ventricular Dysfunction in Pressure Overload-Induced Heart Failure Dabkowski, Erinne R.; O'Connell, Kelly A.; Xu, Wenhong; Ribeiro, Rogerio F., Jr.; Hecker, Peter A.; Shekar, Kadambari Chandra; Daneault, Caroline; Rosiers, Christine Des; Stanley, William C. 分享 收藏
Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction Wang, Hong; Sreenivasan, Urmila; Gong, Da-Wei; O'Connell, Kelly A.; Dabkowski, Erinne R.; Hecker, Peter A.; Ionica, Nicoleta; Konig, Manige; Mahurkar, Anup; Sun, Yezhou; Stanley, William C.; Sztalryd, Carole 分享 收藏
Glucose 6-Phosphate Dehydrogenase Deficiency Increases Redox Stress and Moderately Accelerates the Development of Heart Failure Hecker, Peter A.; Lionetti, Vincenzo; Ribeiro, Rogerio F., Jr.; Rastogi, Sharad; Brown, Bethany H.; O'Connell, Kelly A.; Cox, James W.; Shekar, Kadambari C.; Gamble, Dionna M.; Sabbah, Hani N.; Leopold, Jane A.; Gupte, Sachin A.; Recchia, Fabio A.; Stanley, William C. 分享 收藏
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Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition Khairallah, Ramzi J.; Sparagna, Genevieve C.; Khanna, Nishanth; O'Shea, Karen M.; Hecker, Peter A.; Kristian, Tibor; Fiskum, Gary; Des Rosiers, Christine; Polster, Brian M.; Stanley, William C. 分享 收藏