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A

Andrew R. Thompson

University of Minnesota

H指数:17

被引数:2,358

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Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics

大规模高通量筛选针对心脏ryanodine受体靶向治疗药物

Journal of Biological Chemistry

IF3.9

2025-11-170

OAAI

Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

IF0

2024-05-141

OAAI

Drug discovery for heart failure targeting myosin-binding protein C

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-12-016

OAAI

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

SCIENTIFIC REPORTS

IF3.9

2023-07-0110

OAAI

Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-12-011

OAAI

Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-07-0111

OAAI

Allostery governs Cdk2 activation and differential recognition of CDK inhibitors

NATURE CHEMICAL BIOLOGY

IF13.7

2021-02-0123

OAAI

Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules That Enhance Ca2+ Transport

IF5.2

2020-05-0816

OAAI

Atomistic Models from Orientation and Distance Constraints Using EPR of a Bifunctional Spin Label

BIOPHYSICAL JOURNAL

IF3.1

2019-07-011

OAAI

Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2019-06-217

OAAI

Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states

激酶抑制剂的定量构象分析揭示了极光激酶激活状态的选择性起源

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-0551

OAAI

Structural dynamics of calmodulin-ryanodine receptor interactions: electron paramagnetic resonance using stereospecific spin labels

SCIENTIFIC REPORTS

IF3.9

2018-07-1612

OAAI

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

IF0

2018-02-2155

OAAI

Structural Basis for High-Affinity Actin Binding Revealed by a B-III-Spectrin SCA5 Missense Mutation

BIOPHYSICAL JOURNAL

IF3.1

2018-02-010

OAAI

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

NATURE COMMUNICATIONS

IF15.7

2017-11-0741

OAAI

High-Resolution Structural Dynamics of Bifunctionally Spin-Labeled Myosin by EPR of Oriented Muscle Fibers

BIOPHYSICAL JOURNAL

IF3.1

2017-02-010

OAAI

Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-02-2348

OAAI

Structural Transitions in Myosin I Detected by Conventional and Pulsed EPR of a Bifunctional Spin Label

BIOPHYSICAL JOURNAL

IF3.1

2016-02-010

OAAI

Detecting Structural Changes in Myosin using Bifunctional Spin Labels

BIOPHYSICAL JOURNAL

IF3.1

2016-02-010

OAAI

High-resolution helix orientation in actin-bound myosin determined with a bifunctional spin label

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-06-0814

OAAI