Christian L. Lino Cardenas

Massachusetts General Hospital

27H指数

71论文数

2.8K被引数

收录论文 31

发表时间

Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice 使用定制的CRISPR–Cas9碱基编辑器治疗小鼠中的严重血管疾病

Nature Biomedical Engineering

IF26.6

2025-09-11

PREAI

Christiano R. R. Alves; Sabyasachi Das; Vijai Krishnan; Leillani L. Ha; Lauren R. Fox; Hannah E. Stutzman; Claire E. Shamber; Pazhanichamy Kalailingam; Siobhan McCarthy; Christian L. Lino Cardenas; Claire E. Fong; Takahiko Imai; Sunayana Mitra; Shuqi Yun; Rachael K. Wood; Friederike M. C. Benning; Kangsan Roh; Joseph Lawton; Nahye Kim; Rachel A. Silverstein; Joana Ferreira da Silva; Demitri de la Cruz; Rashmi Richa; Jun Xie; Heather L. Gray-Edwards; Rajeev Malhotra; David Y. Chung; Luke H. Chao; Shengdar Q. Tsai; Casey A. Maguire; Mark E. Lindsay; Benjamin P. Kleinstiver; Patricia L. Musolino

Profiling the metabolome of older adults who live with overweight/obesity and undiagnosed cognitive impairment 对伴有超重/肥胖和未诊断认知障碍的老年人群进行代谢组学分析

neuroscience

IF2.8

2025-07-21

PREAI

Karla Lucia F. Alvarez; Michelle M. Ortiz-Manrique; Gonzalo Davila-Del-Carpio; Antero Peralta-Mestas; Christian L. Lino Cardenas

Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification 全基因组测序揭示了冠状动脉钙化的两个基因座，并将ARSE鉴定为血管钙化的调节剂

cardiovascular research

IF10.8

2023-12-04

OAAI

de Vries, Paul S.; Conomos, Matthew P.; Singh, Kuldeep; Nicholson, Christopher J.; Jain, Deepti; Hasbani, Natalie R.; Jiang, Wanlin; Lee, Sujin; Lino Cardenas, Christian L.; Lutz, Sharon M.; Wong, Doris; Guo, Xiuqing; Yao, Jie; Young, Erica P.; Tcheandjieu, Catherine; Hilliard, Austin T.; Bis, Joshua C.; Bielak, Lawrence F.; Brown, Michael R.; Musharoff, Shaila; Clarke, Shoa L.; Terry, James G.; Palmer, Nicholette D.; Yanek, Lisa R.; Xu, Huichun; Heard-Costa, Nancy; Wessel, Jennifer; Selvaraj, Margaret Sunitha; Li, Rebecca H.; Sun, Xiao; Turner, Adam W.; Stilp, Adrienne M.; Khan, Alyna; Newman, Anne B.; Rasheed, Asif; Freedman, Barry I.; Kral, Brian G.; McHugh, Caitlin P.; Hodonsky, Chani; Saleheen, Danish; Herrington, David M.; Jacobs, David R., Jr.; Nickerson, Deborah A.; Boerwinkle, Eric; Wang, Fei Fei; Heiss, Gerardo; Jun, Goo; Kinney, Greg L.; Sigurslid, Haakon H.; Doddapaneni, Harshavardhan; Hall, Ira M.; Bensenor, Isabela M.; Broome, Jai; Crapo, James D.; Wilson, James G.; Smith, Jennifer A.; Blangero, John; Vargas, Jose D.; Mosquera, Jose Verdezoto; Smith, Joshua D.; Viaud-Martinez, Karine A.; Ryan, Kathleen A.; Young, Kendra A.; Taylor, Kent D.; Lange, Leslie A.; Emery, Leslie S.; Bittencourt, Marcio S.; Budoff, Matthew J.; Montasser, May E.; Yu, Miao; Mahaney, Michael C.; Mahamdeh, Mohammed S.; Fornage, Myriam; Franceschini, Nora; Lotufo, Paulo A.; Natarajan, Pradeep; Wong, Quenna; Mathias, Rasika A.; Gibbs, Richard A.; Do, Ron; Mehran, Roxana; Tracy, Russell P.; Kim, Ryan W.; Nelson, Sarah C.; Damrauer, Scott M.; Kardia, Sharon L. R.; Rich, Stephen S.; Fuster, Valentin; Napolioni, Valerio; Zhao, Wei; Tian, Wenjie; Yin, Xianyong; Min, Yuan-, I; Manning, Alisa K.; Peloso, Gina; Kelly, Tanika N.; O'Donnell, Christopher J.; Morrison, Alanna C.; Curran, Joanne E.; Zapol, Warren M.; Bowden, Donald W.; Becker, Lewis C.; Correa, Adolfo; Mitchell, Braxton D.; Psaty, Bruce M.; Carr, John Jeffrey; Pereira, Alexandre C.; Assimes, Themistocles L.; Stitziel, Nathan O.; Hokanson, John E.; Laurie, Cecelia A.; Rotter, Jerome I.; Vasan, Ramachandran S.; Post, Wendy S.; Peyser, Patricia A.; Miller, Clint L.; Malhotra, Rajeev

Transcriptomic Analysis of Calciphylaxis Tissue Reveals Novel Genes Related to Vascular Calcification and Overlap With Coronary Artery Disease

CIRCULATION

IF38.6

2023-11-07

PREAI

Lee, Sujin; Roh, Kangsan; Singh, Kuldeep; Jiang, Wanlin; Ostrom, Katrina; Birchenough, Claire; Kajuluri, Lova; Johnson, Adam L.; Krinsky, Scott; Bouchouari, Houda; Cardenas, Christian L. Lino

Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis

CELL REPORTS

IF6.9

2023-11-01

OAAI

Mosquera, Jose Verdezoto; Auguste, Gaelle; Wong, Doris; Turner, Adam W.; Hodonsky, Chani J.; Alvarez-Yela, Astrid Catalina; Song, Yipei; Cheng, Qi; Cardenas, Christian L. Lino; Theofilatos, Konstantinos; Bos, Maxime; Kavousi, Maryam; Peyser, Patricia A.; Mayr, Manuel; Kovacic, Jason C.; Bjorkegren, Johan L. M.; Malhotra, Rajeev; Stukenberg, P. Todd; Finn, Aloke, V; van der Laan, Sander W.; Zang, Chongzhi; Sheffield, Nathan C.; Miller, Clint L.

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification 多血统全基因组研究确定冠状动脉钙化的效应基因和药物途径

NATURE GENETICS

IF31.8

2023-09-28

OAAI

Kavousi, Maryam; Bos, Maxime M.; Barnes, Hanna J.; Cardenas, Christian L. Lino; Wong, Doris; Lu, Haojie; Hodonsky, Chani J.; Landsmeer, Lennart P. L.; Turner, Adam W.; Kho, Minjung; Hasbani, Natalie R.; de Vries, Paul S.; Bowden, Donald W.; Chopade, Sandesh; Deelen, Joris; Benavente, Ernest Diez; Guo, Xiuqing; Hofer, Edith; Hwang, Shih-Jen; Lutz, Sharon M.; Lyytikainen, Leo-Pekka; Slenders, Lotte; Smith, Albert V.; Stanislawski, Maggie A.; van Setten, Jessica; Wong, Quenna; Yanek, Lisa R.; Becker, Diane M.; Beekman, Marian; Budoff, Matthew J.; Feitosa, Mary F.; Finan, Chris; Hilliard, Austin T.; Kardia, Sharon L. R.; Kovacic, Jason C.; Kral, Brian G.; Langefeld, Carl D.; Launer, Lenore J.; Malik, Shaista; Hoesein, Firdaus A. A. Mohamed; Mokry, Michal; Schmidt, Reinhold; Smith, Jennifer A.; Taylor, Kent D.; Terry, James G.; van der Grond, Jeroen; van Meurs, Joyce; Vliegenthart, Rozemarijn; Xu, Jianzhao; Young, Kendra A.; Zilhao, Nuno R.; Zweiker, Robert; Assimes, Themistocles L.; Becker, Lewis C.; Bos, Daniel; Carr, J. Jeffrey; Cupples, L. Adrienne; de Kleijn, Dominique P. V.; de Winther, Menno; den Ruijter, Hester M.; Fornage, Myriam; Freedman, Barry I.; Gudnason, Vilmundur; Hingorani, Aroon D.; Hokanson, John E.; Ikram, M. Arfan; Isgum, Ivana; Jacobs, David R., Jr.; Kahonen, Mika; Lange, Leslie A.; Lehtimaki, Terho; Pasterkamp, Gerard; Raitakari, Olli T.; Schmidt, Helena; Slagboom, P. Eline; Uitterlinden, Andre G.; Vernooij, Meike W.; Bis, Joshua C.; Franceschini, Nora; Psaty, Bruce M.; Post, Wendy S.; Rotter, Jerome I.; Bjorkegren, Johan L. M.; O'Donnell, Christopher J.; Bielak, Lawrence F.; Peyser, Patricia A.; Malhotra, Rajeev; van der Laan, Sander W.; Miller, Clint L.

Integrative Single-cell Meta-analysis Reveals Diseaserelevant Vascular Cell States and Markers in Human Atherosclerosis

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2023-05-01

PREAI

Mosquera, Jose E. Verdezoto; Wong, Doris; Auguste, Gaelle; Turner, Adam; Hodonsky, Chani J.; Cardenas, Christian L. Lino; Theofilatos, Konstantinos; Bos, Maxime; Kavousi, Maryam; Peyser, Patricia R.; Mayr, Manuel; Kovacic, Jason; Bjorkegren, Johan; Malhotra, Rajeev; van der Laan, Sander; Zang, Chongzhi; Sheffield, Nathan; Miller, Clint

FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells

CIRCULATION RESEARCH

IF16.2

2023-04-28

OAAI

Wong, Doris; Auguste, Gaelle; Lino Cardenas, Christian L.; Turner, Adam W.; Chen, Yixuan; Song, Yipei; Ma, Lijiang; Perry, R. Noah; Aherrahrou, Redouane; Kuppusamy, Maniselvan; Yang, Chaojie; Mosquera, Jose Verdezoto; Dube, Collin J.; Khan, Mohammad Daud; Palmore, Meredith; Kalra, Jaspreet; Kavousi, Maryam; Peyser, Patricia A.; Matic, Ljubica; Hedin, Ulf; Manichaikul, Ani; Sonkusare, Swapnil K.; Civelek, Mete; Kovacic, Jason C.; Bjorkegren, Johan L. M.; Malhotra, Rajeev; Miller, Clint L.

A seed sequence variant in miR-145-5p causes multisystem smooth muscle dysfunction syndrome

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-03-01

OAAI

Cardenas, Christian Lacks Lino; Briere, Lauren C.; Sweetser, David A.; Lindsay, Mark E.; Musolino, Patricia L.

Co-occurring pathogenic variants in 6q27 associated with dementia spectrum disorders in a Peruvian family

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2023-02-16

OAAI

Alvarez, Karla Lucia F.; Aguilar-Pineda, Jorge Alberto; Ortiz-Manrique, Michelle M.; Paredes-Calderon, Marluve F.; Cardenas-Quispe, Bryan C.; Vera-Lopez, Karin Jannet; Goyzueta-Mamani, Luis D.; Chavez-Fumagalli, Miguel Angel; Davila-Del-Carpio, Gonzalo; Peralta-Mestas, Antero; Musolino, Patricia L.; Lino Cardenas, Christian Lacks

Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2022-11-01

OAAI

Chou, Elizabeth L.; Chaffin, Mark; Simonson, Bridget; Pirruccello, James P.; Akkad, Amer-Denis; Nekoui, Mahan; Cardenas, Christian Lacks Lino; Bedi, Kenneth C., Jr.; Nash, Craig; Juric, Dejan; Stone, James R.; Isselbacher, Eric M.; Margulies, Kenneth B.; Klattenhoff, Carla; Ellinor, Patrick T.; Lindsay, Mark E.

Fibrillar Collagen Variants in Spontaneous Coronary Artery Dissection

JAMA CARDIOLOGY

IF14.1

2022-04-01

OAAI

Zekavat, Seyedeh Maryam; Chou, Elizabeth L.; Zekavat, Melica; Pampana, Akhil; Paruchuri, Kaavya; Cardenas, Christian Lacks Lino; Koyama, Satoshi; Ghazzawi, Yousef; Kii, Erina; Uddin, Md Mesbah; Pirruccello, James; Zhao, Hongyu; Wood, Malissa; Natarajan, Pradeep; Lindsay, Mark E.

Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2022-02-01

OAAI

Malhotra, Rajeev; Nicholson, Christopher J.; Wang, Dongyu; Bhambhani, Vijeta; Paniagua, Samantha; Slocum, Charles; Sigurslid, Haakon H.; Cardenas, Christian L. Lino; Li, Rebecca; Boerboom, Sophie L.; Chen, Yin-Ching; Hwang, Shih-Jen; Yao, Chen; Ichinose, Fumito; Bloch, Donald B.; Lindsay, Mark E.; Lewis, Gregory D.; Aragam, Jayashri R.; Hoffmann, Udo; Mitchell, Gary F.; Hamburg, Naomi M.; Vasan, Ramchandran S.; Benjamin, Emelia J.; Larson, Martin G.; Zapol, Warren M.; Cheng, Susan; Roh, Jason D.; O'Donnell, Christopher J.; Nguyen, Christopher; Levy, Daniel; Ho, Jennifer E.

In Silico Analysis of Metabolites from Peruvian Native Plants as Potential Therapeutics against Alzheimer's Disease

MOLECULES

IF4.6

2022-01-28

OAAI

Goyzueta-Mamani, Luis Daniel; Barazorda-Ccahuana, Haruna Luz; Chavez-Fumagalli, Miguel Angel; F. Alvarez, Karla Lucia; Aguilar-Pineda, Jorge Alberto; Vera-Lopez, Karin Jannet; Lino Cardenas, Christian Lacks

Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm

CIRCULATION

IF38.6

2021-05-25

OAAI

Oller, Jorge; Gabande-Rodriguez, Enrique; Ruiz-Rodriguez, Maria Jesus; Desdin-Mico, Gabriela; Aranda, Juan Francisco; Rodrigues-Diez, Raquel; Ballesteros-Martinez, Constanza; Blanco, Eva Maria; Roldan-Montero, Raquel; Acuna, Pedro; Forteza Gil, Alberto; Martin-Lopez, Carlos E.; Nistal, J. Francisco; Lino Cardenas, Christian L.; Lindsay, Mark Evan; Martin-Ventura, Jose Luis; Briones, Ana M.; Miguel Redondo, Juan; Mittelbrunn, Maria

Estimating risk of mechanical ventilation and in-hospital mortality among adult COVID-19 patients admitted to Mass General Brigham: The VICE and DICE scores

ECLINICALMEDICINE

IF10

2021-03-01

OAAI

Nicholson, Christopher J.; Wooster, Luke; Sigurslid, Haakon H.; Li, Rebecca H.; Jiang, Wanlin; Tian, Wenjie; Cardenas, Christian L. Lino; Malhotra, Rajeev

Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits 紫杉醇药物涂层球囊血管成形术抑制兔实验性动脉粥样硬化的进展和炎症

JACC-BASIC TO TRANSLATIONAL SCIENCE

IF7.2

2020-07-01

OAAI

Chowdhury, Mohammed M.; Singh, Kanwarpal; Albaghdadi, Mazen S.; Khraishah, Haitham; Mauskapf, Adam; Kessinger, Chase W.; Osborn, Eric A.; Kellnberger, Stephan; Piao, Zhonglie; Cardenas, Christian L. Lino; Grau, Madeleine S.; Jaff, Michael R.; Rosenfield, Kenneth; Libby, Peter; Edelman, Elazer R.; Lindsay, Mark E.; Tearney, Guillermo J.; Jaffer, Farouc A.

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease

SCIENTIFIC REPORTS

IF3.9

2020-06-19

OAAI

Thayer, Timothy E.; Cardenas, Christian L. Lino; Martyn, Trejeeve; Nicholson, Christopher J.; Traeger, Lisa; Wunderer, Florian; Slocum, Charles; Sigurslid, Haakon; Shakartzi, Hannah R.; O'Rourke, Caitlin; Shelton, Georgia; Buswell, Mary D.; Barnes, Hanna; Neitzel, Leif R.; Ledsky, Clara D.; Li, Jason Pingcheng; Burke, Megan F.; Farber-Eger, Eric; Perrien, Daniel S.; Kumar, Ravindra; Corey, Kathleen E.; Wells, Quinn S.; Bloch, Kenneth D.; Hong, Charles C.; Bloch, Donald B.; Malhotra, Rajeev

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

NATURE GENETICS

IF31.8

2019-10-28

106

OAAI

Malhotra, Rajeev; Mauer, Andreas C.; Cardenas, Christian L. Lino; Guo, Xiuqing; Yao, Jie; Zhang, Xiaoling; Wunderer, Florian; Smith, Albert, V; Wong, Quenna; Pechlivanis, Sonali; Hwang, Shih-Jen; Wang, Judy; Lu, Lingyi; Nicholson, Christopher J.; Shelton, Georgia; Buswell, Mary D.; Barnes, Hanna J.; Sigurslid, Haakon H.; Slocum, Charles; O'Rourke, Caitlin; Rhee, David K.; Bagchi, Aranya; Nigwekar, Sagar U.; Buys, Emmanuel S.; Campbell, Catherine Y.; Harris, Tamara; Budoff, Matthew; Criqui, Michael H.; Rotter, Jerome, I; Johnson, Andrew D.; Song, Ci; Franceschini, Nora; Debette, Stephanie; Hoffmann, Udo; Kaelsch, Hagen; Noethen, Markus M.; Sigurdsson, Sigurdur; Freedman, Barry, I; Bowden, Donald W.; Jckel, Karl-Heinz; Moebus, Susanne; Erbel, Raimund; Feitosa, Mary F.; Gudnason, Vilmundur; Thanassoulis, George; Zapol, Warren M.; Lindsay, Mark E.; Bloch, Donald B.; Post, Wendy S.; O'Donnell, Christopher J.

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2019-07-15

PREAI

Savary, Gregoire; Dewaeles, Edmone; Diazzi, Serena; Buscot, Matthieu; Nottet, Nicolas; Fassy, Julien; Courcot, Elisabeth; Henaoui, Imene-Sarah; Lemaire, Julie; Martis, Nihal; Van der Hauwaert, Cynthia; Pons, Nicolas; Magnone, Virginie; Leroy, Sylvie; Hofman, Veronique; Plantier, Laurent; Lebrigand, Kevin; Paquet, Agnes; Cardenas, Christian L. Lino; Vassaux, Georges; Hofman, Paul; Guenther, Andreas; Crestani, Bruno; Wallaert, Benoit; Rezzonico, Roger; Brousseau, Thierry; Glowacki, Francois; Bellusci, Saverio; Perrais, Michael; Broly, Franck; Barbry, Pascal; Marquette, Charles-Hugo; Cauffiez, Christelle; Mari, Bernard; Pottier, Nicolas

研究方向