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C

Chris Soon Heng Tan

college of science

25H指数
103论文数
2.9K被引数
收录论文 40
发表时间
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Proteome stability and dynamic protein complex profiling identified EEF1A1 as a novel translation regulator of autophagy and mitophagy蛋白质组稳定性及动态蛋白质复合物分析鉴定EEF1A1为自噬和线粒体自噬的新型翻译调控因子
errCell Communication and Signaling
IF8.9
err2026-08-19
err0
errOAAI
errShuang Zhang; Ya Zeng; Fengming Li; Bin Liao; Jun Wang; Jiahong Lu; Chris Soon Heng Tan
err分享
err收藏
Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D使用SNPdrug3D分析不同人群中药物结合与药物遗传变异的基因组景观
errNature Communications
IF15.7
err2026-06-09
err0
errOAAI
errAshar J. Malik; Dimitar Kenanov; Cheng-Shoong Chong; Mert Burak Ozturk; Qiqi Wang; Hong-Yun Chang; Maxime Hebrard; Ying Swan Ho; Zhenxun Wang; Vachiranee Limviphuvadh; Jhoann M. T. Miyajima; Srinivasaraghavan Kannan; Roberto Tirado Magallanes; Xueling Sim; Jin Fang Chai; Sonia Davila; Khung Keong Yeo; Khai Pang Leong; Liuh Ling Goh; Neerja Karnani; Johan Gunnar Eriksson; Ching-Yu Cheng; Tien Yin Wong; Marie Loh; Rinkoo Dalan; Chiea Chuen Khor; Guo-Liang Chew; Weng Khong Lim; Joanne Ngeow; John C. Chambers; E. Shyong Tai; Nicolas Bertin; Chris Soon Heng Tan; Judice Koh; Patrick Tan; Chandra S. Verma; Sebastian Maurer-Stroh
err分享
err收藏
DeepDrugDiscovery identifies blood–brain barrier permeable autophagy enhancers for Alzheimer’s diseaseDeepDrugDiscovery鉴定出可透过血脑屏障的自噬增强剂，用于阿尔茨海默病治疗
errNature Biomedical Engineering
IF26.6
err2026-04-24
err0
PREAI
errYu Dong; Xianglu Xiao; Xu-Xu Zhuang; Wenfan Wu; Zi-Ying Wang; Shuang Zhang; Jin-Tao Li; Ke Zhang; Wen-Yu Fu; Jun-Ming Chen; Shi Hang Xiong; Shenglong Deng; Krinos Li; Chao Ma; Wangzhen Jin; Xurui Jin; Qiwei Cai; Han-Ming Shen; Min Li; Huanxing Su; Jian-Bo Wan; Hua Yu; Defang Ouyang; Keqiang Ye; Evandro F. Fang; Chris Soon Heng Tan; Guang Yang; Zhangming Niu; Jia-Hong Lu
err分享
err收藏
Machine learning-enhanced discovery of contextual biomolecular interactions from diverse large-scale perturbation data基于机器学习的多样大规模扰动数据中上下文生物分子相互作用的发现
errKnowledge-Based Systems
IF7.6
err2026-03-05
err0
PREAI
errYa Zeng; Qiqi Wang; Shuang Zhang; Fengming Li; Qiufen Chen; Jun (Joelle) Wang; Chris Soon Heng Tan
err分享
err收藏
Covalent Organic Framework with Acid Precipitation Enhances Microprotein Enrichment and Discovery of Ferroptosis-Associated Microproteins共价有机骨架与酸沉淀增强微蛋白富集及铁死亡相关微蛋白的发现
errAnalytical Chemistry
IF6.7
err2026-03-03
err0
PREAI
errFengming Li; Jingchen Sui; Xiaoqian Wang; Bin Liao; Ying Zhang; Shuang Zhang; Hailiang Hu; Teck Yew Low; Changzheng Du; Chris Soon Heng Tan
err分享
err收藏
Unnatural amino acid-based miniPROTACs enable efficient oncoprotein degradation非天然氨基酸基微型PROTACs实现癌蛋白高效降解
errActa Pharmaceutica Sinica B
IF14.6
err2026-03-02
err0
errOAAI
errJianchao Zhang; Xiao Chen; Congli Chen; Fengming Li; Kefan Liao; Xiaoxiao Song; Ya Zeng; Jie Wang; Ming-Yuan Su; Chris Soon Heng Tan; Lijing Fang; Hai Rao
err分享
err收藏
BioFusionDTI: Assimilating Graph and Sequence Modalities for Generalizable Drug-Target Interaction Prediction
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-12-01
err0
PREAI
errChen, Qiufen; Nie, Guanyan; Li, Xiaoli; Xu, Ying; Tan, Chris Soon Heng
err分享
err收藏
Fangchinoline suppresses melanoma metastasis by inducing senescence of circulating tumor cellsFangchinoline通过诱导循环肿瘤细胞衰老抑制黑色素瘤转移。
errBiomedicine & Pharmacotherapy
IF7.5
err2025-11-15
err0
errOAAI
errJunhao Chen; Jianyang Hu; Jiapeng He; Binyu Zhang; Haoyuan Tan; Qiqi Wang; Hailiang Hu; Suling Xu; Chris Soon Heng Tan; Jianglin Zhang; Xin Hong
err分享
err收藏
A Pseudomonas aeruginosa quorum-sensing metabolite manipulates macrophage ferroptosis through a methylation pathway铜绿假单胞菌（Pseudomonas aeruginosa）的一种群体感应代谢物通过甲基化通路调控巨噬细胞铁死亡。
errNature Communications
IF15.7
err2025-11-13
err0
errOAAI
errTianyuan Jia; Fengming Li; Tianzhen Li; Anmin Ren; Peiyi Lu; Yiling Liu; Yachun Zhou; Xiangke Duan; Yang Liu; Lin Zhong; Zhirong Zhang; Chris Soon Heng Tan; Liang Yang
err分享
err收藏
Integrated thermal proteome and thermal proximity co-aggregation profiling identifies ATP6V1C1 as a novel anti-cancer drug target整合热蛋白质组学和热邻近共聚集谱分析鉴定ATP6V1C1为一种新型的抗肿瘤药物靶点
errINTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
IF10
err2025-04-28
err0
errOAAI
errZhang, Shuang; Li, Feng-Ming; Wang, Jun; Dong, Yu; Luo, Jing-Fang; Huang, Xiao-Fang; Li, Yue; Zhu, Guo-Yuan; Qi, Shi-Qian; Shen, Han-Ming; Zhong, Qing; Ming, Chen; Zeng, Ke-Wu; Yao, Xiao-Jun; Tan, Chris Soon Heng; Lu, Jia-Hong
err分享
err收藏
A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging (vol 11, pg 76, 2025)一种通过互补成像实现精确诊断肝癌的荧光探针组合 (vol 11, pg 76, 2025)
errACS CENTRAL SCIENCE
IF10.4
err2025-03-04
err0
errOAAI
errGao, M; Lee, SH; Kwon, HY; Ciaramicoli, LM; Jo, E; Yu, YH; Li, FM; Kim, B; Hong, K; Lee, JS; Kim, N; Oh, Y; Im, CY; Tan, CSH; Ha, HH; Chang, YT
err分享
err收藏
A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging
errACS CENTRAL SCIENCE
IF10.4
err2024-12-16
err0
errOAAI
errGao, Min; Lee, Sun Hyeok; Kwon, Haw-Young; Ciaramicoli, Larissa Miasiro; Jo, Eunsol; Yu, Young Hyun; Li, Fengming; Kim, Beomsue; Hong, Kyungtae; Lee, Jun-Seok; Kim, Namhui; Oh, Yoojin; Im, Chun Young; Tan, Chris Soon Heng; Ha, Hyung-Ho; Chang, Young-Tae
err分享
err收藏
Spike-In Proteome Enhances Data-Independent Acquisition for Thermal Proteome Profiling
errANALYTICAL CHEMISTRY
IF6.7
err2024-12-02
err0
PREAI
errWang, Qiqi; Chen, Qiufen; Lin, Yue; He, Dan; Ji, Hongchao; Tan, Chris Soon Heng
err分享
err收藏
Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-08
err0
PREAI
errZhang, Jianchao; Chen, Xiao; Chen, Congli; Li, Fengming; Song, Xiaoxiao; Liu, Chaowei; Liao, Kefan; Su, Ming-Yuan; Tan, Chris Soon Heng; Fang, Lijing; Rao, Hai
err分享
err收藏
Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers
errCANCER DISCOVERY
IF33.3
err2024-06-17
err0
PREAI
errShanmugam, Raghuvaran; Majee, Prativa; Shi, Wei; Ozturk, Mert B.; Vaiyapuri, Thamil S.; Idzham, Khaireen; Raju, Anandhkumar; Shin, Seung H.; Fidan, Kerem; Low, Joo-Leng; Chua, Joelle Y. H.; Kong, Yap C.; Qi, Ong Y.; Tan, Emile; Chok, Aik Y.; Seow-En, Isaac; Wee, Ian; Macalinao, Dominique C.; Chong, Dawn Q.; Chang, Hong Y.; Lee, Fiona; Leow, Wei Q.; Murata-Hori, Maki; Xiaoqian, Zhang; Shumei, Chia; Tan, Chris S. H.; Dasgupta, Ramanuj; Tan, Iain B.; Tergaonkar, Vinay
err分享
err收藏
High-throughput drug target discovery using a fully automated proteomics sample preparation platform
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err4
errOAAI
errWu, Qiong; Zheng, Jiangnan; Sui, Xintong; Fu, Changying; Cui, Xiaozhen; Liao, Bin; Ji, Hongchao; Luo, Yang; He, An; Lu, Xue; Xue, Xinyue; Tan, Chris Soon Heng; Tian, Ruijun
err分享
err收藏
Protein painting for structural and binding site analysis via intracellular lysine reactivity profiling with o-phthalaldehyde
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err2
errOAAI
errZheng, Zhenxiang; Zeng, Ya; Lai, Kunjia; Liao, Bin; Li, Pengfei; Tan, Chris Soon Heng
err分享
err收藏
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation
errNATURE COMMUNICATIONS
IF15.7
err2023-11-24
err4
errOAAI
errSun, Siyuan; Zheng, Zhenxiang; Wang, Jun; Li, Fengming; He, An; Lai, Kunjia; Zhang, Shuang; Lu, Jia-Hong; Tian, Ruijun; Tan, Chris Soon Heng
err分享
err收藏
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions
errCELL CHEMICAL BIOLOGY
IF7.2
err2023-11-01
err7
errOAAI
errJi, Hongchao; Lu, Xue; Zhao, Shiji; Wang, Qiqi; Liao, Bin; Bauer, Ludwig G.; Huber, Kilian V. M.; Luo, Ray; Tian, Ruijun; Tan, Chris Soon Heng
err分享
err收藏
Scaled-Down Thermal Profiling and Coaggregation Analysis of the Proteome for Drug Target and Protein Interaction Analysis
errANALYTICAL CHEMISTRY
IF6.7
err2023-09-01
err8
PREAI
errLu, Xue; Liao, Bin; Sun, Siyuan; Mao, Yiheng; Wu, Qiong; Tian, Ruijun; Tan, Chris Soon Heng
err分享
err收藏

研究方向

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