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M

Michael‐Christopher Keogh

Laval University
H指数:34
被引数:7,327
浏览量:0

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Nucleosome context regulates chromatin reader preference

核小体环境调控染色质读码器偏好

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-110
PRE
Marunde, Matthew R.; Popova, Irina K.; Hall, Nathan W.; Vaidya, Anup; Bone, James R.; Boone, Brandon A.; Brown, Peter J.; Ezell, Ryan J.; Firestone, Tessa M.; Fuchs, Harrison A.; Gibson, Elisa; Gillespie, Zachary B.; Gloor, Susan L.; Hickman, Allison R.; Howard, Sarah A.; Husby, Natalia Ledo; Hsiung, Victoria T.; Johnstone, Andrea L.; Khan, Laiba F.; Krajewski, Krzysztof; Lee, Alexander S.; Mcanarney, Eileen T.; Maier, Keith E.; Maryanski, Danielle N.; McCuiston, Jamie L.; Noll, Kelsey E.; Novitzky, Katherine; Patteson, Emily F.; Rodriguez, Keli L.; Sanchez, Julio C.; Schachner, Luis F.; Smith, Catherine E.; Sun, Lu; Taylor, Hailey F.; Watson, Rachel; Willis, Hannah E.; Musselman, Catherine A.; Venters, Bryan J.; Cheek, Marcus A.; Meiners, Matthew J.; Sun, Zu-Wen; Kelleher, Neil L.; Cowles, Martis W.; Weinzapfel, Ellen N.; Keogh, Michael-Christopher; Burg, Jonathan M.
NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers

NSD2抑制剂通过重塑染色质来治疗肺癌和胰腺癌

Nature
IF48.5
2025-08-060
PRE
Jinho Jeong; Simone Hausmann; Hanyang Dong; Kacper Szczepski; Natasha M. Flores; Andy Garcia Gonzalez; Liyang Shi; Xiaoyin Lu; Joanna Lempiäinen; Moritz Jakab; Liyong Zeng; Tourkian Chasan; Eric Bareke; Rui Dong; Emma Carlson; Reinnier Padilla; Dylan Husmann; Julia Thompson; Gerry A. Shipman; Emily Zahn; Courtney A. Barnes; Laiba F. Khan; Liz Marie Albertorio-Sáez; Eva Brill; Vishnu Udayakumar Sunita Kumary; Matthew R. Marunde; Danielle N. Maryanski; Cheryl C. Szany; Bryan J. Venters; Carolina Lin Windham; Michal Eligiusz Nowakowski; Iwona Czaban; Mariusz Jaremko; Michael-Christopher Keogh; Kang Le; Michael J. Soth; Benjamin A. Garcia; Łukasz Jaremko; Jacek Majewski; Pawel K. Mazur; Or Gozani
Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response

PHRF1的PHD finger对组蛋白H3 N末端的识别对于正常的DNA损伤应答是必需的。

NUCLEIC ACIDS RESEARCH
IF13.1
2025-07-220
PRE
Jain, Kanishk; Tchara, Pata-Eting Kougnassoukou; Khan, Abid; Mengistalem, Amanuel B.; Holland, Aidan P.; Bowman, Christopher N.; Marunde, Matthew R.; Engel, Tiffany A.; Popova, Irina K.; Cooke, Spencer W.; Krajewski, Krzysztof; Keogh, Michael-Christopher; Lambert, Jean-Philippe; Strahl, Brian D.
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch
SCIENCE ADVANCES
IF12.5
2024-08-302
OAAI
Gretarsson, Kristjan H.; Abini-Agbomson, Stephen; Gloor, Susan L.; Weinberg, Daniel N.; McCuiston, Jamie L.; Kumary, Vishnu Udayakumar Sunitha; Hickman, Allison R.; Sahu, Varun; Lee, Rachel; Xu, Xinjing; Lipieta, Natalie; Flashner, Samuel; Adeleke, Oluwatobi A.; Popova, Irina K.; Taylor, Hailey F.; Noll, Kelsey; Windham, Carolina Lin; Maryanski, Danielle N.; Venters, Bryan J.; Nakagawa, Hiroshi; Keogh, Michael-Christopher; Armache, Karim-Jean; Lu, Chao
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation (vol 30, pg 1503, 2023)
CELL STEM CELL
IF20.4
2024-02-010
OA
Chen, Chun-Wei; Zhang, Linda; Dutta, Ravi; Niroula, Abhishek; Miller, Peter G.; Gibson, Christopher J.; Bick, Alexander G.; Reyes, Jaime M.; Lee, Yi -Tang; Tovy, Ayala; Gu, Tianpeng; Waldvogel, Sarah; Chen, Yi-Hung; Venters, Bryan J.; Esteve, Pierre -Olivier; Pradhan, Sriharsa; Keogh, Michael-Christopher; Natarajan, Pradeep; Takahashi, Koichi; Sperling, Adam S.; Goodell, Margaret A.
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
CANCER RESEARCH
IF16.6
2024-01-090
PRE
Leuzzi, Giuseppe; Vasciaveo, Alessandro; Taglialatela, Angelo; Chen, Xiao; Firestone, Tessa M.; Hickman, Allison R.; Mao, Wendy; Thakar, Tanay; Vaitsiankova, Alina; Huang, Jen-Wei; Cuella-Martin, Raquel; Hayward, Samuel B.; Kesner, Jordan S.; Ghasemzadeh, Ali; Nambiar, Tarun S.; Ho, Patricia; Rialdi, Alexander; Hebrard, Maxime; Li, Yinglu; Gao, Jinmei; Gopinath, Saarang; Adeleke, Oluwatobi A.; Venters, Bryan; Drake, Charles G.; Baer, Richard; Izar, Benjamin; Guccione, Ernesto; Keogh, Michael-Christopher; Guerois, Raphael; Sun, Lu; Lu, Chao; Califano, Andrea; Ciccia, Alberto
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
SCIENCE ADVANCES
IF12.5
2023-08-1113
OAAI
Thomas, Jonathan F.; Valencia-Sanchez, Marco Igor; Tamburri, Simone; Gloor, Susan L.; Rustichelli, Samantha; Godinez-Lopez, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M.; Hickman, Allison R.; Sun, Lu; Gopinath, Saarang; Taylor, Hailey F.; Sun, Zu-Wen; Ezell, Ryan J.; Vaidya, Anup; Meiners, Matthew J.; Cheek, Marcus A.; Rice, William J.; Svetlov, Vladimir; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean
An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
ELIFE
IF0
2023-05-1915
OA
Jain, Kanishk; Marunde, Matthew R.; Burg, Jonathan M.; Gloor, Susan L.; Joseph, Faith M.; Poncha, Karl F.; Gillespie, Zachary B.; Rodriguez, Keli L.; Popova, Irina K.; Hall, Nathan W.; Vaidya, Anup; Howard, Sarah A.; Taylor, Hailey F.; Mukhsinova, Laylo; Onuoha, Ugochi C.; Patteson, Emily F.; Cooke, Spencer W.; Taylor, Bethany C.; Weinzapfel, Ellen N.; Cheek, Marcus A.; Meiners, Matthew J.; Fox, Geoffrey C.; Namitz, Kevin E. W.; Cowles, Martis W.; Krajewski, Krzysztof; Sun, Zu-Wen; Cosgrove, Michael S.; Young, Nicolas L.; Keogh, Michael-Christopher; Strahl, Brian D.

研究方向

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M
Matthew R. Marunde
H 指数:15论文数:57被引数:1,345
N
Nevan J. Krogan
H 指数:129论文数:756被引数:6.8万
J
Jonathan M. Burg
H 指数:12论文数:40被引数:922
Z
Zu‐Wen Sun
H 指数:19论文数:41被引数:5,401
B
Bryan J. Venters
H 指数:20论文数:79被引数:3,528
S
Stephen Buratowski
H 指数:73论文数:184被引数:2.3万
M
Matthew J. Meiners
H 指数:12论文数:30被引数:1,312
A
Allison R. Hickman
H 指数:7论文数:24被引数:218
M
Marcus A. Cheek
H 指数:13论文数:33被引数:1,414
M
Martis W. Cowles
H 指数:15论文数:49被引数:902