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N

Nevan J. Krogan

gladstone institutes
H指数:129
被引数:6.8万

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Whole-exome sequencing in individuals with obsessive–compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes

对强迫症和慢性抽动障碍个体进行全外显子组测序鉴定出36个具有大效应的风险基因

2026-09-010
OA
The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism

微环境通过HSF1介导的代谢调控糖免疫监视

2026-08-070
OA
A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells

人类诱导多能干细胞的基因组规模CRISPRi扰动图谱

2026-07-010
PRE
Human genetic variation associates with infection by derived Ugandan M. tuberculosis lineage

人类遗传变异与派生乌干达分枝杆菌结核分枝杆菌谱系的感染相关

2026-01-010
OA
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
2025-12-010
PRE
The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

Mac1 ADP-核糖基水解酶是SARS-CoV-2的 therapeutic target。

2025-11-191
OA
Author Correction: Brahma safeguards canalization of cardiac mesoderm differentiation

作者更正: 梵文保护心脏中胚层分化的渠化

Nature
IF48.5
2025-11-180
OAAI
Pharmacological reprogramming of plitidepsin as a SARS-CoV-2 inhibitor

plitidepsin的药理重编程作为SARS-CoV-2抑制剂

2025-11-100
PRE
Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction

溶酶体蛋白质组学揭示了神经元APOE4相关溶酶体功能障碍的机制

Autophagy
IF14.3
2025-11-070
OAAI
Integrative Multi-Omics Analysis In Vivo Identifies Influenza A Virus Host Factors

整合多组学活体分析鉴定出甲型流感病毒宿主因子

2025-09-240
OAAI
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy

基于结构的具有高生物利用度、共价键、广谱冠状病毒MPro抑制剂的发现,并具有强体内效力

2025-04-250
OA
Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders

整合的多组学表征揭示了与神经发育障碍相关的突触RNA加工因子和泛素连接酶。

2025-04-011
OAAI
The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection

Chlamydia效应蛋白Dre1通过与动力蛋白相关蛋白复合体(dynactin)结合,在感染过程中重新定位宿主细胞器。

2025-04-010
OAAI
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6
2025-03-010
OAAI
Affinity Purification Mass Spectrometry on the Orbitrap-Astral Mass Spectrometer Enables High-Throughput Protein-Protein Interaction Mapping

Orbitrap-Astral质谱仪上的亲和纯化质谱可实现高通量蛋白质-蛋白质相互作用图谱

2025-03-010
OA