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DEREGULATION OF SPINDLE ASSEMBLY CHECKPOINTS VIA TRIP13 UPREGULATION LEADS TO LOSS OF HETEROZYGOSITY IN AGGRESSIVE CHROMOPHOBE RENAL CELL CARCINOMA AND MAY BE A PROMISING THERAPEUTIC TARGET 通过TRIP13上调调控有丝分裂纺锤体装配检查点导致恶性肾嫌色细胞癌杂合性缺失，并可能成为有前景的治疗靶点 Ellis, Elizabeth; Maulding, Nathan; Akagi, Keiko; Yu, Zhiyuan; Karki, Menuka; Scott, Nicholas; Pesquera, Pedro; Qian, Jing; Duan, Fei; Grover, Abha; Beauchamp, Kyle; Karbasi, Kaveh; Guinney, Justin; Sedgewick, Andrew; Sircar, Kanishka; Soto, Luisa Solis; Karam, Jose; Msaouel, Pavlos; Zacharias, Niki 分享 收藏
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Phase 2 trial of metastasis directed radiotherapy without systemic therapy (MRWS) for oligometastatic clear cell renal cell carcinoma (ccRCC) and investigation of circulating tumor DNA (ctDNA) 针对寡转移性透明细胞肾细胞癌(ccRCC)的靶向转移放疗(MRWS)且不联合系统治疗的Ⅱ期临床试验，并探究循环肿瘤DNA(ctDNA) Tang, Chad; Sherry, Alex; Seo, Aaron; Hara, Kieko; Choi, Haesun; Liu, Suyu; Sun, Xiaowen; Montoya, Anya; Ludmir, Ethan; Shah, Amishi Y.; Jonasch, Eric; Zurita-Saavedra, Amado J.; Kovitz, Craig; Battey, Christopher; Ratzel, Sarah; Genovese, Giannicola; Sircar, Kanishka; Karam, Jose; Tannir, Nizar; Msaouel, Pavlos 分享 收藏
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Testicular Cancer, Version 2.2025 Featured Updates to the NCCN Guidelines 睾丸癌，版本 2.2025 NCCN 指南特色更新 Gilligan, Timothy; Lin, Daniel W.; Adra, Nabil; Bagrodia, Aditya; Feldman, Darren R.; Yamoah, Kosj; Aggarwal, Rahul; Chandrasekar, Thenappan; Costa, Daniel; Drakaki, Alexandra; Eggener, Scott; Emamekhoo, Hamid; Geynisman, Daniel M.; Graham, Laura; Humphrey, Peter; Leuva, Harshraj; Levine, Ellis G.; Luckenbaugh, Amy; Maughan, Benjamin L.; Mcgregor, Bradley; Monk, Paul; Picus, Jool; Pierorazio, Phillip; Rais-Bahrami, Soroush; Reichert, Zachery; Rwigema, Jean-Claude; Saylor, Philip; Shah, Ankeet; Shah, Sumit; Singla, Nirmish; Sircar, Kanishka; Vanderweele, David; Zhumkhawala, Ali; Montgomery, Sarah; Sliker, Bailee 分享 收藏
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Delta-like ligand 3 (DLL3) landscape in pulmonary and extra-pulmonary neuroendocrine neoplasms Serrano, Alejandra G.; Rocha, Pedro; Lima, Cibelle Freitas; Stewart, Allison; Zhang, Bingnan; Diao, Lixia; Fujimoto, Junya; Cardnell, Robert J.; Lu, Wei; Khan, Khaja; Sable, Beate; Ellison, Aaron R.; Wistuba, Ignacio I.; Concannon, Kyle F.; Halperin, Daniel M.; Bogdan, Czerniak; Sircar, Kanishka; Zhang, Miao; Cargill, Kasey; Wang, Qi; Aparicio, Ana; Lazar, Alexander; Hernandez, Sharia; Estrella, Jeannelyn; Ramalingam, Preetha; El-Naggar, Adel; Kalhor, Neda; Gay, Carl M.; Byers, Lauren Averett; Soto, Luisa M. Solis 分享 收藏
Design of high-performance tumor-informed minimal residual disease (MRD) panels from low FFPE tumor input LaBella, Matt; Acevedo, Ashley; Patel, Ravi; Haug, Kiefer; Ganesh, Sangita; Buser, Elise; Xu, Nafei; Carlson, Shalee; Trettin, Kyle; Ratzel, Sarah; Hara, Kieko; Msaouel, Pavlos; Sircar, Kanishka; Tang, Chad; Muzzey, Dale; Gould, Genevieve 分享 收藏
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer 干扰素信号促进肾癌转移进化过程中对染色体不稳定性的耐受性 Perelli, Luigi; Carbone, Federica; Zhang, Li; Huang, Justin K. K.; Le, Courtney; Khan, Hania; Citron, Francesca; Del Poggetto, Edoardo; Gutschner, Tony; Tomihara, Hideo; Soeung, Melinda; Minelli, Rosalba; Srinivasan, Sanjana; Peoples, Michael; Lam, Truong Nguyen Anh; Lundgren, Sebastian; Xia, Ruohan; Zhu, Cihui; Mohamed, Alaa M. T.; Zhang, Jianhua; Sircar, Kanishka; Sgambato, Alessandro; Gao, JianJun; Jonasch, Eric; Draetta, Giulio F.; Futreal, Andrew; Bakouny, Ziad; Van Allen, Eliezer M.; Choueiri, Toni; Signoretti, Sabina; Msaouel, Pavlos; Litchfield, Kevin; Turajlic, Samra; Wang, Linghua; Chen, Ying Bei; Di Natale, Renzo G.; Hakimi, A. Ari; Giuliani, Virginia; Heffernan, Timothy P.; Viale, Andrea; Bristow, Christopher A.; Tannir, Nizar M.; Carugo, Alessandro; Genovese, Giannicola 分享 收藏
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A phase 1-2 trial of sitravatinib and nivolumab in clear cell renal cell carcinoma following progression on antiangiogenic therapy 抗血管生成治疗进展后，sitratinib和nivolumab在透明细胞肾细胞癌中的1-2期试验 Msaouel, Pavlos; Goswami, Sangeeta; Thall, Peter F.; Wang, Xuemei; Yuan, Ying; Jonasch, Eric; Gao, Jianjun; Campbell, Matthew T.; Shah, Amishi Yogesh; Corn, Paul Gettys; Tam, Alda L.; Ahrar, Kamran; Rao, Priya; Sircar, Kanishka; Cohen, Lorenzo; Basu, Sreyashi; Duan, Fei; Jindal, Sonali; Zhang, Yuwei; Chen, Hong; Yadav, Shalini S.; Shazer, Ronald; Der-Torossian, Hirak; Allison, James P.; Sharma, Padmanee; Tannir, Nizar M. 分享 收藏
Testicular Cancer, Version 2.2020 Gilligan, Timothy; Lin, Daniel W.; Aggarwal, Rahul; Chism, David; Cost, Nicholas; Derweesh, Ithaar H.; Emamekhoo, Hamid; Feldman, Darren R.; Geynisman, Daniel M.; Hancock, Steven L.; LaGrange, Chad; Levine, Ellis G.; Longo, Thomas; Lowrance, Will; McGregor, Bradley; Monk, Paul; Picus, Joel; Pierorazio, Phillip; Rais-Bahrami, Soroush; Saylor, Philip; Sircar, Kanishka; Smith, David C.; Tzou, Katherine; Vaena, Daniel; Vaughn, David; Yamoah, Kosj; Yamzon, Jonathan; Johnson-Chilla, Alyse; Keller, Jennifer; Pluchino, Lenora A. 分享 收藏
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Integrated transcriptomic-genomic tool Texomer profiles cancer tissues Wang, Fang; Zhang, Shaojun; Kim, Tae-Beom; Lin, Yu-yu; Iqbal, Ramiz; Wang, Zixing; Mohanty, Vakul; Sircar, Kanishka; Karam, Jose A.; Wendl, Michael C.; Meric-Bernstam, Funda; Weinstein, John N.; Ding, Li; Mills, Gordon B.; Chen, Ken 分享 收藏
Uc.416+A promotes epithelial-to-mesenchymal transition through miR-153 in renal cell carcinoma Sekino, Yohei; Sakamoto, Naoya; Goto, Keisuke; Honma, Ririno; Shigematsu, Yoshinori; Thang Pham Quoc; Sentani, Kazuhiro; Oue, Naohide; Teishima, Jun; Kawakami, Fumi; Karam, Jose A.; Sircar, Kanishka; Matsubara, Akio; Yasui, Wataru 分享 收藏
Protein Expression of PTTG1 as a Diagnostic Biomarker in Adrenocortical Carcinoma Arenas, Minerva Angelica Romero; Whitsett, Timothy G.; Aronova, Anna; Henderson, Samuel A.; LoBello, Janine; Habra, Mouhammed Amir; Grubbs, Elizabeth G.; Lee, Jeffrey E.; Sircar, Kanishka; Zarnegar, Rasa; Scognamiglio, Theresa; Fahey, Thomas J.; Perrier, Nancy D.; Demeure, Michael J. 分享 收藏
Outcomes of Patients with Renal Cell Carcinoma and Sarcomatoid Dedifferentiation Treated with Nephrectomy and Systemic Therapies: Comparison between the Cytokine and Targeted Therapy Eras Keskin, Sarp K.; Msaouel, Pavlos; Hess, Kenneth R.; Yu, Kai-Jie; Matin, Surena F.; Sircar, Kanishka; Tamboli, Pheroze; Jonasch, Eric; Wood, Christopher G.; Karam, Jose A.; Tannir, Nizar M. 分享 收藏
Programmed cell death ligand 1 and tumor-infiltrating lymphocyte status in patients with renal cell carcinoma and sarcomatoid dedifferentiation Kawakami, Fumi; Sircar, Kanishka; Rodriguez-Canales, Jaime; Fellman, Bryan M.; Urbauer, Diana L.; Tamboli, Pheroze; Tannir, Nizar M.; Jonasch, Eric; Wistuba, Ignacio I.; Wood, Christopher G.; Karam, Jose A. 分享 收藏
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